Relationship of age and liveweight at first calving to subsequent lactation yields of Friesian heifers grazing tropical pastures

The relationship between age at first calving, liveweight at first calving and milk yield in the first lactation was studied on 78 purebred Friesian heifers grazing tropical pastures without supplementation. In addition, 61 and 41 records of milk yield in the second and third lactations respectively were analysed for relationship to liveweight at first calving. Age at calving was not significantly related to milk yield in the first lactation, though liveweight at first calving was significantly related to milk yield in the first (r = 0·57; P < 0·01), second (r = 0·51; P < 0·01) and third (r = 0·46; P < 0·01) lactations. The regression coefficient showed a slight, though non-significant, decrease with succeeding lactations. Possible explanations for this relationship and application of the results are discussed

Performance of temperate perennial pastures in the Australian subtropics 2. Milk production

Milk production from irrigated, pure stands of perennial ryegrass (Lolium perenne cv. Yatsyn), prairie grass (Bromus willdenodii cv. Matua) and tall fescue (Festuca arundinacea cv. AU Triumph) were compared with that achieved from Italian ryegrass (L. multiflorum cv. Concord) over 3 lactations of multiparous Holstein–Friesian cows at Mutdapilly in south-east Queensland. Pastures were fertilised with 50 kg nitrogen/ha . month as urea and annual dressings of 20 kg phosphorus/ha and 50 kg potassium/ha (as superphosphate and muriate of potash respectively). There were 4 pasture treatments grazed at 3 cows/ha in a 1-week-on, 3-weeks-off rotation with 2 replicates and 3 cows/treatment block. Cows grazed the pastures day and night from May to November. Over summer, cows grazed the pastures during the night and were fed supplements (silage in the first lactation, and lucerne hay in the second and third lactations) during the day because there was no shade available in the irrigation areas. In autumn, the animals were removed from the ryegrass and prairie grass pastures for 8 weeks to allow seedling re-establishment, either by oversowing (ryegrasses) or natural reseeding (prairie grass). Cows continued to graze the fescue pastures at night during autumn. All cows received a ration of 4 kg/cow of a grain–minerals mixture in the first lactation and 5 kg/cow in the second and third lactations. Milk production from perennial ryegrass was higher than from fescue in the first lactation and Italian ryegrass in the second and third lactations. Prairie grass gave similar milk production to perennial ryegrass in all 3 years. In the third year, perennial ryegrass, prairie grass and fescue gave similar milk production. Milk quality from the 4 grasses was similar except in the third lactation when the lactose content of milk from perennial ryegrass pastures was lowest. There were also small and inconsistent differences in milk component yields between the 4 grasses. Liveweight changes were small except in the second lactation when the cows grazing fescue lost weight relative to the other treatments. Mean liveweight at calving increased over the 3 lactations. It was concluded that all 3 temperate perennial grasses demonstrated useful traits for use in subtropical dairy pastures. Perennial ryegrass produced the most milk from the lowest amount of dry matter on offer. Prairie grass produced similar milk yields to perennial ryegrass, was well eaten by cattle and was self regenerating. Although fescue was slower to establish and needed more intensive management to control maturity, it was the most persistent and was the only grass to provide autumn grazing. In the second year this attribute resulted in a lower requirement for supplementary feeding. Fescue produced the highest gross margin in the second lactation and was only marginally less than prairie grass in the third. The performance of Italian ryegrass was as good as that of perennial ryegrass in the first lactation but fell substantially in the second and third lactations as the level of summer grass invasion increased

Mycobacterium tuberculosis lineage: a naming of the parts

There have been many reports of groups of related Mycobacterium tuberculosis strains described variously as lineages, families or clades. There is no objective definition of these groupings making it impossible to define relationships between those groups with biological advantages. Here we describe two groups of related strains obtained from an epidemiological study in Tanzania which we define as the Kilimanjaro and Meru lineages on the basis of IS6110 restriction fragment length polymorphism (RFLP), polymorphic GC rich sequence (PGRS) RFLP and mycobacterial interspersed repeat unit (MIRU) typing. We investigated the concordance between each of the typing techniques and the dispersal of the typing profiles from a core pattern. The Meru lineage is more dispersed than the Kilimanjaro lineage and we speculate that the Meru lineage is older. We suggest that this approach provides an objective definition that proves robust in this epidemiological study. Such a framework will permit associations between a lineage and clinical or bacterial phenomenon to be tested objectively. This definition will also enable new putative lineages to be objectively tested

Perspectives and Update on the Global Shortage of Verteporfin (Visudyne).

An ongoing global shortage of verteporfin (Visudyne &lt;sup&gt;®&lt;/sup&gt; ) limits the treatment possibilities for several chorioretinal diseases, including central serous chorioretinopathy, choroidal hemangioma, and polypoidal choroidal vasculopathy. Verteporfin is required to perform photodynamic therapy in these ocular diseases. Therefore, the current situation has a substantial impact on eye care worldwide. The worldwide supply of verteporfin appears to be manufactured by a single factory, which is situated in the United States. The distribution of verteporfin is done by different companies for different regions of the world. Official communication on the shortage by the responsible companies has been scarce and over the past years several promises with regards to resolution of the shortage have not been fulfilled. The delivery of new batches of verteporfin is at irregular intervals, unpredictable, and may not be fairly balanced between different regions or countries in the world. To ensure a fair distribution of available verteporfin within a country, several measures can be taken. In the Netherlands, a national committee, consisting of ophthalmologists, is in place to arrange this. On the European level, the European Union and European Medicine Agency have plans to monitor medicine shortages more closely and to intervene if necessary. With a more intensified monitoring and regulation of medicine supplies, future impending shortages may be prevented. Remarkably, the amount of medicine shortages is increasing, having a significant and sometimes irreversible impact on patient care. Thus, efforts should be undertaken to minimize the consequences and, whenever possible, to prevent future medicine shortages

Three-spined stickleback armour predicted by body size, minimum winter temperature and pH

Similar phenotypes evolve under equivalent environmental conditions through parallel evolution. Because they have repeatedly invaded and adapted to new freshwater environments, the three-spined stickleback (Gasterosteus aculeatus) offers a powerful system for understanding the agents of selection in nature that drive parallel evolution. Here we examine the ecological and environmental variables responsible for morphological variation in three-spined stickleback populations across its European range. We collected fish from 85 populations, encompassing much of the European latitudinal range of the species and including lowland rivers and lakes, coastal lagoons, and moorland ponds. We measured biotic and environmental variables at all sites along with morphological traits for 2,358 individuals. Using an information theory approach, we identified body size, minimum average winter temperature and pH as primary predictors of stickleback armour evolution, challenging current hypotheses for stickleback morphological diversification and demonstrating the fundamental role played by body size and scaling in mediating responses to selection. Stickleback lateral plate phenotype represents a potentially powerful tool for monitoring change in climate variables across the northern temperate region

Quasinormal modes from potentials surrounding the charged dilaton black hole

We clarify the purely imaginary quasinormal frequencies of a massless scalar perturbation on the 3D charged-dilaton black holes. This case is quite interesting because the potential-step appears outside the event horizon similar to the case of the electromagnetic perturbations on the large Schwarzschild-AdS black holes. It turns out that the potential-step type provides the purely imaginary quasinormal frequencies, while the potential-barrier type gives the complex quasinormal modes.Comment: 19 pages, 8 figure

Energy Loss versus Shadowing in the Drell-Yan Reaction on Nuclei

We present a new analysis of the E772 and E866 experiments on the nuclear dependence of Drell-Yan (DY) lepton pair production resulting from the bombardment of $^2H$, Be, C, Ca, Fe, and W targets by 800 GeV/c protons at Fermilab. We employ a light-cone formulation of the DY reaction in the rest frame of the nucleus, where the dimuons detected at small values of Bjorken x_2 << 1 may be considered to originate from the decay of a heavy photon radiated from an incident quark in a bremsstrahlung process. We infer the energy loss of the quark by examining the suppression of the nuclear-dependent DY ratios seen as a function of projectile momentum fraction x_1 and dimuon mass M. Shadowing, which also leads to nuclear suppression of dimuons, is calculated within the same approach employing the results of phenomenological fits to deep inelastic scattering data from HERA. The analysis yields -dE/dz =2.73 +/- 0.37 +/- 0.5 GeV/fm for the rate of quark energy loss per unit path length, a value consistent with theoretical expectations including the effects of the inelastic interaction of the incident proton at the surface of the nucleus. This is the first observation of a nonzero energy loss effect in such experiments.Comment: 43 pages including 17 figure

Search for flavor-changing neutral currents and lepton-family-number violation in two-body D0 decays

Results of a search for the three neutral charm decays, D0 -> mu e, D0 -> mu mu, and D0 -> e e, are presented. This study was based on data collected in Experiment 789 at the Fermi National Accelerator Laboratory using 800 GeV/c proton-Au and proton-Be interactions. No evidence is found for any of the decays. Upper limits on the branching ratios, at the 90% confidence level, are obtained.Comment: 28 pages, 18 figures. Submitted to Physical Review

Patterns of aeolian deposition in subtropical Australia through the last glacial and deglacial periods

Published online by Cambridge University Press: 08 February 2021Debate about the nature of climate and the magnitude of ecological change across Australia during the last glacial maximum (LGM; 26.5–19 ka) persists despite considerable research into the late Pleistocene. This is partly due to a lack of detailed paleoenvironmental records and reliable chronological frameworks. Geochemical and geochronological analyses of a 60 ka sedimentary record from Brown Lake, subtropical Queensland, are presented and considered in the context of climate-controlled environmental change. Optically stimulated luminescence dating of dune crests adjacent to prominent wetlands across North Stradbroke Island (Minjerribah) returned a mean age of 119.9 ± 10.6 ka; indicating relative dune stability soon after formation in Marine Isotope Stage 5. Synthesis of wetland sediment geochemistry across the island was used to identify dust accumulation and applied as an aridification proxy over the last glacial-interglacial cycle. A positive trend of dust deposition from ca. 50 ka was found with highest influx occurring leading into the LGM. Complexities of comparing sedimentary records and the need for robust age models are highlighted with local variation influencing the accumulation of exogenic material. An inter-site comparison suggests enhanced moisture stress regionally during the last glaciation and throughout the LGM, returning to a more positive moisture balance ca. 8 ka.Richard J. Lewis, John Tibby, Lee J. Arnold, Patricia Gadd, Geraldine Jacobsen, Cameron Bar

Magnetic Fields in the Milky Way

This chapter presents a review of observational studies to determine the magnetic field in the Milky Way, both in the disk and in the halo, focused on recent developments and on magnetic fields in the diffuse interstellar medium. I discuss some terminology which is confusingly or inconsistently used and try to summarize current status of our knowledge on magnetic field configurations and strengths in the Milky Way. Although many open questions still exist, more and more conclusions can be drawn on the large-scale and small-scale components of the Galactic magnetic field. The chapter is concluded with a brief outlook to observational projects in the near future.Comment: 22 pages, 5 figures, to appear in "Magnetic Fields in Diffuse Media", eds. E.M. de Gouveia Dal Pino and A. Lazaria