198 research outputs found

    Employee Well-Being During COVID-19 Pandemic: The Role of Adaptability, Work-Family Conflict, and Organizational Response

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    Well-being has always been a topic of interest for individuals, organizations, and policy-makers. COVID-19 pandemic made it tremendously relevant as employees were forced to work from home due to the successive lockdowns that governments have implemented to curb the spread of the virus. This crisis has raised concerns about employees’ well-being due to the implementation of these tight measures. In the present study, we examined the direct and indirect effects of employees’ adaptability, work-family conflict, and organizational response on employees’ well-being through the mediating role of perceived stress. Data have been collected from 184 employees working in various organizations in Malaysia and analyzed using Smart-PLS Structural Equation Modeling with the bootstrapping procedure. The results indicated that organizational response, work-family conflict, and adaptability directly affect perceived stress and well-being, except for organizational response, which has no direct effect on well-being. Furthermore, it was found that perceived stress mediates the relationship of organizational response and work-family conflict with well-being but not adaptability

    The influence of doping with Ca and Mg in YBa2Cu3O7-δ ceramic

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    We have investigated the effect of partial substitution of Ca for Y and/or Mg for Cu on structural, compositional and magnetic properties in γBa 2 Cu 3 O 7-δ polycrystalline compounds. All prepared samples were found to be single phase with small fraction of Ba-secondary phases. Substitution by more than 2% of magnesium causes an increase of spurious phases. Energy Dispersive Spectroscopy (EDS) revealed that the distribution of Ca in the sample is quite homogenous. DC susceptibility measurements show that superconducting transition temperature Tc is reduced much more by Ca than Mg. Hysteresis loops reveal that magnetic irreversibility is decreased by Ca and Mg content. The deduced critical current density Jc does not follow the same variation. Ca alone reduces Jc for x=0.1 and x=0.2. Together with Ca, Mg compensates the reduction of Jc and increasing its content near the solubility limit gives higher Jc than in the undoped sample

    The required knowledge and skills from Libyan university accounting education and barriers to development: A mixed methods study using an institutional theory lens

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    The business environment worldwide has witnessed remarkable changes, which require education to respond. However, accounting bodies and organisations have become concerned about the expansion of the gap between what is being taught in accounting education programmes (AEPs) and what are the requirements of the labour market. Much of this debate has focused on developed countries, but the same issues are likely to apply, but perhapsin different form, in emerging economies too. Using Libya as an example of an emerging economy, this research examines professionals’, practitioners’ and educators’ perceptions regarding three things: the required knowledge and skills; the gap that exists in both university accounting students and employees; and the institutional influences and barriers that may affect the development of university AEPs. Institutional theory was adopted as a lens to help guide and explain the findings. In order to fulfil the research objectives, a mixed method exploratory study design was used. This design included two phases: twelve Viber and Skype interviews were conducted, then 262 valid online questionnaire responses were collected. Thematic analysis of the interview transcripts was conducted, then the questionnaire responses were analysed, mainly using Welch’s ANOVA. The emerged themes showed that what is considered important for AEPs can be classified into three areas: technical knowledge (e.g. financial accounting, auditing, and awareness of ethical issues in accounting and auditing); generic skills such as teamwork, reading with understanding, and analysis skills; and IT skills (e.g. electronic accounting systems and World Wide Web). Most stakeholders were not satisfied with the development level that students exhibited in important competencies. The failures of Libyan AEPs were attributed to teaching and faculty member-related issues, student-related issues, curricula-related issues, and collaboration-related issues. Different institutional influences shape and affect AEPs. Coercive isomorphic pressures stem from the dependency of the universities upon government funding, and the previous regime’s attempts to politicize education. Mimetic isomorphic influences result from different channels, including curricula, teaching methods experience brought by abroad-educated academics, and the good relationship between Libya and the previous colonizer. The study contributes to a knowledge gap in the accounting education literature from an emerging economy context, where educators consider the gap between the required skills and development level in their students even larger than that perceived by professionals and practitioners. Using institutional theory as a lens to answer the research questions provides evidence of the influences that accounting educators in Libya face. As well as following up this project in other emerging economies, further research should consider the voices of students and recent graduates as key stakeholders

    Visualization of Distributed Algorithms Based on Graph Relabelling Systems1 1This work has been supported by the European TMR research network GETGRATS, and by the “Conseil Régional d' Aquitane”.

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    AbstractIn this paper, we present a uniform approach to simulate and visualize distributed algorithms encoded by graph relabelling systems. In particular, we use the distributed applications of local relabelling rules to automatically display the execution of the whole distributed algorithm. We have developed a Java prototype tool for implementing and visualizing distributed algorithms. We illustrate the different aspects of our framework using various distributed algorithms including election and spanning trees

    Intermittent selective clamping improves rat liver regeneration by attenuating oxidative and endoplasmic reticulum stress.

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    International audienceIntermittent clamping of the portal trial is an effective method to avoid excessive blood loss during hepatic resection, but this procedure may cause ischemic damage to liver. Intermittent selective clamping of the lobes to be resected may represent a good alternative as it exposes the remnant liver only to the reperfusion stress. We compared the effect of intermittent total or selective clamping on hepatocellular injury and liver regeneration. Entire hepatic lobes or only lobes to be resected were subjected twice to 10 min of ischemia followed by 5 min of reperfusion before hepatectomy. We provided evidence that the effect of intermittent clamping can be damaging or beneficial depending to its mode of application. Although transaminase levels were similar in all groups, intermittent total clamping impaired liver regeneration and increased apoptosis. In contrast, intermittent selective clamping improved liver protein secretion and hepatocyte proliferation when compared with standard hepatectomy. This beneficial effect was linked to better adenosine-5'-triphosphate (ATP) recovery, nitric oxide production, antioxidant activities and endoplasmic reticulum adaptation leading to limit mitochondrial damage and apoptosis. Interestingly, transient and early chaperone inductions resulted in a controlled activation of the unfolded protein response concomitantly to endothelial nitric oxide synthase, extracellular signal-regulated kinase-1/2 (ERK1/2) and p38 MAPK activation that favors liver regeneration. Endoplasmic reticulum stress is a central target through which intermittent selective clamping exerts its cytoprotective effect and improves liver regeneration. This procedure could be applied as a powerful protective modality in the field of living donor liver transplantation and liver surgery

    IGL-1 solution reduces endoplasmic reticulum stress and apoptosis in rat liver transplantation

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    Injury due to cold ischemia reperfusion (I/R) is a major cause of primary graft non-function following liver transplantation. We postulated that I/R-induced cellular damage during liver transplantation might affect the secretory pathway, particularly at the endoplasmic reticulum (ER). We examined the involvement of ER stress in organ preservation, and compared cold storage in University of Wisconsin (UW) solution and in Institute Georges Lopez-1 (IGL-1) solution. In one group of rats, livers were preserved in UW solution for 8 h at 4 °C, and then orthotopic liver transplantation was performed according to Kamada's cuff technique. In another group, livers were preserved in IGL-1 solution. The effect of each preservation solution on the induction of ER stress, hepatic injury, mitochondrial damage and cell death was evaluated. As expected, we found increased ER stress after liver transplantation. IGL-1 solution significantly attenuated ER damage by reducing the activation of three pathways of unfolded protein response and their effector molecules caspase-12, C/EBP homologous protein-10, X-box-binding protein 1, tumor necrosis factor-associated factor 2 and eukaryotic translation initiation factor 2. This attenuation of ER stress was associated with a reduction in hepatic injury and cell death. Our results show that IGL-1 solution may be a useful means to circumvent excessive ER stress reactions associated with liver transplantation, and may optimize graft quality

    Striae Distensae: In Vitro Study and Assessment of Combined Treatment With Sodium Ascorbate and Platelet-Rich Plasma on Fibroblasts

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    Introduction: Striae distensae (SD) appear clinically as parallel striae, lying perpendicular to the tension lines of the skin. SD evolve into two clinical phases, an initial inflammatory phase in which they are called “striae rubrae” (SR) and a chronic phase in which they are called striae albae (SA). Fibroblasts seem to play a key role in the pathogenesis of stretch marks. This study was aimed at describing and analyzing stretch marks-derived fibroblasts (SMF), the differences between SR- and SA-derived fibroblasts (SRF, SAF), testing two treatments in vitro (sodium ascorbate and PrP) on SAF. Material and Methods: To characterize the SMF, the expression of alpha smooth muscle actin (alpha SMA) was investigated. Type I collagen expression was measured in SAF, before and after adding different PrP concentrations and sodium ascorbate in the culture medium. Results were processed through statistical analysis models using the Student’s t-test. Results: A significant increase in alpha SMA (P <0.001) was observed in SRF. SAF treated with PrP and sodium ascorbate showed a resumption of their metabolic activity by an increase in collagen type I production and cell proliferation. After 24 h of incubation with PrP 1% and PrP 5% + sodium ascorbate, cell viability was increased by 140% and 151% and by 156 and 178% after 48 h, respectively, compared to the control. Conclusion: Our study shows that a biologically mediated improvement in SMF metabolic activity is possible. Our promising results require further trials to be able to confirm the reproducibility of this combined treatment, particularly in vivo. No Level Assigned: This journal requires that authors assign a level of evidence to each submission to which Evidence-Based Medicine rankings are applicable

    First analysis of a numerical benchmark for 2D columnar solidification of binary alloys

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    International audienceDuring the solidification of metal alloys, chemical heterogeneities at the product scale (macrosegregation) develop. Numerical simulation tools are beginning to appear in the industry, however their predictive capabilities are still limited. We present a numerical benchmark exercise treating the performance of models in the prediction of macrosegregation. In a first stage we defined a "minimal" (i.e. maximally simplified) solidification model, describing the coupling of the solidification of a binary alloy and of the transport phenomena (heat, solute transport and fluid flow) that lead to macrosegregation in a fully columnar ingot with a fixed solid phase. This model is solved by four different numerical codes, employing different numerical methods (FVM and FEM) and various solution schemes. We compare the predictions of the evolution of macrosegregation in a small (10Ă—6 cm) ingot of Sn-10wt%Pb alloys. Further, we present the sensitivities concerning the prediction of instabilities leading to banded channel mesosegregations

    Compact and Highly Sensitive Bended Microwave Liquid Sensor Based on a Metamaterial Complementary Split-Ring Resonator

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    YesIn this paper, we present the design of a compact and highly sensitive microwave sensor based on a metamaterial complementary split-ring resonator (CSRR), for liquid characterization at microwave frequencies. The design consists of a two-port microstrip-fed rectangular patch resonating structure printed on a 20 × 28 mm2 Roger RO3035 substrate with a thickness of 0.75 mm, a relative permittivity of 3.5, and a loss tangent of 0.0015. A CSRR is etched on the ground plane for the purpose of sensor miniaturization. The investigated liquid sample is put in a capillary glass tube lying parallel to the surface of the sensor. The parallel placement of the liquid test tube makes the design twice as efficient as a normal one in terms of sensitivity and Q factor. By bending the proposed structure, further enhancements of the sensor design can be obtained. These changes result in a shift in the resonant frequency and Q factor of the sensor. Hence, we could improve the sensitivity 10-fold compared to the flat structure. Subsequently, two configurations of sensors were designed and tested using CST simulation software, validated using HFSS simulation software, and compared to structures available in the literature, obtaining good agreement. A prototype of the flat configuration was fabricated and experimentally tested. Simulation results were found to be in good agreement with the experiments. The proposed devices exhibit the advantage of exploring multiple rapid and easy measurements using different test tubes, making the measurement faster, easier, and more cost-effective; therefore, the proposed high-sensitivity sensors are ideal candidates for various sensing applications.This work was supported by the Moore4Medical project, funded within ECSEL JU in collaboration with the EU H2020 Framework Programme (H2020/2014–2020) under grant agreement H2020-ECSEL-2019-IA-876190, and the Fundação para a Ciência e Tecnologia (ECSEL/0006/2019). This project received funding in part from the DGRSDT (Direction Générale de la Recherche Scientifique et du Développement Technologique), MESRS (Ministry of Higher Education and Scientific Research), Algeria. This work was also supported by the General Directorate of Scientific Research and Technological Development (DGRSDT)–Ministry of Higher Education and Scientific Research (MESRS), Algeria, and funded by the FCT/MEC through national funds and, when applicable, co-financed by the ERDF, under the PT2020 Partnership Agreement under the UID/EEA/50008/2020 project
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