137 research outputs found

    Reconsidering Israel's Past

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    Un des chefs de file de la nouvelle histoire en Israël, qu'on qualifie également de post-sioniste, met en question la rhétorique sionisto-nationaliste qui, pour des raisons idéologiques, quitte à faire une lecture des faits souvent unilatérale, a produit une historiographie conforme à ses vœux. L'ouverture de nouveaux fonds d'archives, l'évolution des mentalités en Israël, l'affaiblissement de l'idéologie sioniste font qu'aujourd'hui s'impose dans certains cercles intellectuels une nouvelle grille de lecture des événements, notamment ceux qui concernent les Arabes au premier chef

    Reconsidering Israel's Past

    Get PDF
    Un des chefs de file de la nouvelle histoire en Israël, qu'on qualifie également de post-sioniste, met en question la rhétorique sionisto-nationaliste qui, pour des raisons idéologiques, quitte à faire une lecture des faits souvent unilatérale, a produit une historiographie conforme à ses vœux. L'ouverture de nouveaux fonds d'archives, l'évolution des mentalités en Israël, l'affaiblissement de l'idéologie sioniste font qu'aujourd'hui s'impose dans certains cercles intellectuels une nouvelle grille de lecture des événements, notamment ceux qui concernent les Arabes au premier chef

    Nonmyeloablative regimen preserves "niches" allowing for peripheral expansion of donor T-cells

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    AbstractT-cell recovery following myeloablative preparatory regimens and cord blood transplantation in adult patients gen erally occurs between 1 and 3 years following allogeneic bone marrow transplantation. T-cell reconstitution may involve thymic education of donor-derived precursors or peripheral expansion of mature T-cells transferred in the graft. We measured quantitative and qualitative immunologic reconstitution, T-cell receptor spectratyping, and T-cell receptor excision circle (TREC) levels in adult recipients of umbilical cord blood transplants following a novel nonmyeloablative regimen. These results were compared to previously published results of similar patients receiving a myeloablative regimen and cord blood stem cells. With small numbers of patients treated so far, T-cells (CD3+) reached normal levels in adults 6 to 12 months following nonmyeloablative transplantation compared with 24 months in adults receiving a myeloablative regimen. At 12 months after transplantation, the numbers of phenotypically naive (CD45RA) T-cells were higher in those receiving the nonmyeloablative regimen. The T-cell repertoire in cord blood recipients treated with a nonmyeloablative regimen was markedly more diverse and robust compared with the repertoire in those receiving the myeloablative regimen at similar time points. TRECs (which are generated within the thymus and identify new thymic emigrants and those that have not divided) were detected 12 months after transplantation in the nonmyeloablative recipients, whereas TRECs were not detected in adults until 18 to 24 months in those receiving myeloablative regimens. Thus, in adults receiving a nonmyeloablative preparatory regimen, the quantitative and qualitative recovery of T-cells occurs through rapid peripheral expansion. The ability of patients receiving a nonmyeloablative regimen to recover within a few months suggests that the peripheral niches in which T-cells can proliferate are preserved in these patients compared to those receiving ablative regimens. Moreover, the presence of TREC-positive cells within 1 year suggests that thymic recovery is likewise accelerated in non myeloablative compared to myeloablative regimens.Biol Blood Marrow Transplant 2002;8(5):249-56

    Abiotic Input of Fixed Nitrogen by Bolide Impacts to Gale Crater During the Hesperian : Insights From the Mars Science Laboratory

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    We acknowledge the NASA Mars Science Laboratory Program, Centre National d'Études Spatiales, the Universidad Nacional Autónoma de México (PAPIIT IN109416, IN111619, and PAPIME PE103216), and the Consejo Nacional de Ciencia y Tecnología de México (CONACyT 220626) for their support. We thank Fred Calef for constructing Figure 4 and appreciate the interest and support received from John P. Grotzinger and Joy A. Crisp throughout the Curiosity mission. The authors are grateful to the SAM and MSL teams for successful operation of the SAM instrument and the Curiosity rover. The data used in this paper are listed in the supporting information, figures, and references. SAM Data contained in this paper are publicly available through the NASA Planetary Data System at http://pds‐geosciences.wustl.edu/missions/msl/sam.htm. We would like to express gratitude to Pierre‐Yves Meslin from the Research Institute in Astrophysics and Planetology at Toulouse, France, and five anonymous reviewers whose comments/suggestions on earlier drafts helped improve and clarify this manuscript. The authors declare no conflicts of interests.Peer reviewedPublisher PD

    Notes for genera: basal clades of Fungi (including Aphelidiomycota, Basidiobolomycota, Blastocladiomycota, Calcarisporiellomycota, Caulochytriomycota, Chytridiomycota, Entomophthoromycota, Glomeromycota, Kickxellomycota, Monoblepharomycota, Mortierellomycota, Mucoromycota, Neocallimastigomycota, Olpidiomycota, Rozellomycota and Zoopagomycota)

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    Compared to the higher fungi (Dikarya), taxonomic and evolutionary studies on the basal clades of fungi are fewer in number. Thus, the generic boundaries and higher ranks in the basal clades of fungi are poorly known. Recent DNA based taxonomic studies have provided reliable and accurate information. It is therefore necessary to compile all available information since basal clades genera lack updated checklists or outlines. Recently, Tedersoo et al. (MycoKeys 13:1--20, 2016) accepted Aphelidiomycota and Rozellomycota in Fungal clade. Thus, we regard both these phyla as members in Kingdom Fungi. We accept 16 phyla in basal clades viz. Aphelidiomycota, Basidiobolomycota, Blastocladiomycota, Calcarisporiellomycota, Caulochytriomycota, Chytridiomycota, Entomophthoromycota, Glomeromycota, Kickxellomycota, Monoblepharomycota, Mortierellomycota, Mucoromycota, Neocallimastigomycota, Olpidiomycota, Rozellomycota and Zoopagomycota. Thus, 611 genera in 153 families, 43 orders and 18 classes are provided with details of classification, synonyms, life modes, distribution, recent literature and genomic data. Moreover, Catenariaceae Couch is proposed to be conserved, Cladochytriales Mozl.-Standr. is emended and the family Nephridiophagaceae is introduced

    L'historiographie de Deir Yassin

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    Reconsidering Israel's Past

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    Un des chefs de file de la nouvelle histoire en Israël, qu'on qualifie également de post-sioniste, met en question la rhétorique sionisto-nationaliste qui, pour des raisons idéologiques, quitte à faire une lecture des faits souvent unilatérale, a produit une historiographie conforme à ses vœux. L'ouverture de nouveaux fonds d'archives, l'évolution des mentalités en Israël, l'affaiblissement de l'idéologie sioniste font qu'aujourd'hui s'impose dans certains cercles intellectuels une nouvelle grille de lecture des événements, notamment ceux qui concernent les Arabes au premier chef. EB.Morris Benny. Reconsidering Israel's Past. In: CEMOTI, n°28, 1999. Turquie Israël. pp. 119-126

    1948: a history of the first Arab-Israeli war

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