75 research outputs found

    Absentismo laboral en trabajadores públicos de Mallorca

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    Objetivo. Valorar los procesos de absentismo en una empresa pública en el periodo 1991-2008 y la influencia de algunas variables socio demográficas. Material y método. Estudio descriptivo transversal un total de 10154 procesos de absentismo (incapacidad temporal, accidente de trabajo e indisposición) en trabajadores públicos. Se analiza la influencia de la edad y el sexo. Resultados. Se estudian un total de 6542 episodios de incapacidad temporal, 2297 indisposiciones y 615 accidentes laborales. El número total de días perdidos es de 302147. Las mujeres y los trabajadores mayores de 45 años son los grupos que presentan mayor número de procesos de absentismo y los que pierden mayor número de días. Conclusiones. El presente trabajo es uno de los primeros que presenta datos de indisposiciones, un aspecto del absentismo que muy pocas veces se ha analizado.Objective. Assess the processes of absenteeism in a public company between 1991-2008 and the influence of some socio demographic variables. Methods. Cross-sectional study of 10154 absences processes (temporary disability, industrial accident and mild ailments) in public workers. The influence of age and sex is analyzed. Results. 6542 episodes of temporary disability, 2297 mild ailments and 615 industrial accidents were studied. The total number of “lost days” is 302147. Women and workers over 45 are the groups with the highest number of absenteeism processes and more “lost days”. Conclusions. This work is one of the first to present data of mild ailments, one aspect of absenteeism rarely been analyzed

    FTIR-ATR Spectroscopy Combined with Multivariate Regression Modeling as a Preliminary Approach for Carotenoids Determination in Cucurbita spp

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    Quantitative analysis of carotenoids has been extensively reported using UV\u2010Vis spectrophotometry and chromatography, instrumental techniques that require complex extraction protocols with organic solvents. Fourier transform infrared spectroscopy (FTIR) is a potential alternative for simplifying the analysis of food constituents. In this work, the application of FTIR with attenuated total reflectance (ATR) was evaluated for the determination of total carotenoid content (TCC) in Cucurbita spp. samples. Sixty\u2010three samples, belonging to different cultivars of butternut squash (C. moschata) and pumpkin (C. maxima), were selected and analyzed with FTIR\u2010 ATR (attenuated total reflectance). Three different preparation protocols for samples were followed: homogenization (A), freeze\u2010drying (B), and solvent extraction (C). The recorded spectra were used to develop regression models by Partial Least Squares (PLS), using data from TCC, determined by UV\u2010Vis spectrophotometry. The PLS regression model obtained with the FTIR data from the freeze\u2010dried samples, using the spectral range 920\u20133000 cm 121, had the best figures of merit (R2CAL of 0.95, R2PRED of 0.93 and RPD of 3.78), being reliable for future application in agriculture. This approach for carotenoid determination in pumpkin and squash avoids the use of organic solvents. Moreover, these results are a rationale for further exploring this technique for the assessment of specific carotenoids in food matrices

    Evaluación basada en el método del gradiente de las propiedades elásticas de tejidos humanos in vivo

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    [EN] Nowadays the computational simulation of the mechanical behaviour of human tissues in the medical context is a field which has aroused a great interest in the scientific community. The study of the behaviour of those tissues carries a great difficulty, in part, due to the fact that the behaviour of those tissues is different from one patient to another and, in general, it is no possible to make empirical experiments with the tissue to determine its elastic properties. In order to circumvent this issue, in this work we propose a method to evaluate these properties assuming a Mooney-Rivlin constitutive model. The proposed method is based on the information provided by medical images and two different deformation states of the organ and, by using a gradient-based optimization process we accurately obtain the elastic properties of the constitutive model. The numerical experiments show the validity of the method for the example used.[ES] En la actualidad la simulación numérica del comportamiento mecánico de tejidos humanos en el campo de la medicina es un ámbito de estudio que ha despertado gran interés en la comunidad científica. El estudio del comportamiento de dichos tejidos conlleva una gran dificultad, en parte, atribuida al hecho de que su comportamiento cambia de paciente a paciente y en numerosas ocasiones no es posible realizar experimentos directos sobre el tejido para determinar sus propiedades elásticas. Para tal fin, en el presente trabajo se propone un método para hallar dichas propiedades asumiendo un modelo constitutivo de Mooney-Rivlin. Dicho método se basa en la información proporcionada por imágenes médicas en dos situaciones de deformación del órgano y, mediante un proceso de optimización basado en el gradiente se obtienen, con precisión, las propiedades elásticas del modelo constitutivo. Los experimentos numéricos realizados demuestran la validez del método para el ejemplo utilizado, tras comprobar que las propiedades del modelo constituvo de referencia son obtenidas por el método propuesto.Nadal, E.; Rupérez Moreno, MJ.; Martinez-Sanchis, S.; Monserrat Aranda, C.; Tur Valiente, M.; Fuenmayor Fernández, FJ. (2017). Evaluación basada en el método del gradiente de las propiedades elásticas de tejidos humanos in vivo. Revista UIS Ingenierías. 16(1):15-22. doi:10.18273/revuin.v16n1-2017002S152216

    Microsatellite Marker in Gamma - Aminobutyric Acid - A Receptor Beta 3 Subunit Gene and Autism Spectrum Disorders in Korean Trios

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    This study aimed to identify the association between gamma-aminobutyric acid-A (GABA-A) receptor subunit β3 (GABRB3) gene and autism spectrum disorders (ASD) in Korea. Fifty-eight children with ASD [47 boys (81.0%), 5.5 ± 4.1 years old], 46 family trios, and 86 healthy control subjects [71 males (82.6%), 33.6 ± 9.3 years old] were recruited. Transmission disequilibrium test revealed that, 183 bp long allele in GABRB3 gene was preferentially transmitted in families with ASD (p = 0.025), whereas a population-based case-control study, however, showed no association between ASD and GABRB3 microsatellite polymorphism. Our data provide preliminary evidence that GABRB3 gene is associated with ASD in Korea

    Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

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    The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

    Evolution and pathology in Chagas disease: a review

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    Round table with Empeños/Trials artists

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    In this round table, Mexican theatre practitioners will discuss their performance and the student members will discuss the process of translation. Note that this is attached to the presentation of the theatre piece that Dr. Cowling is hosting. Dr. Cowling has been in touch with the research office about the possible timing of this event. Faculty Mentor: Dr. Erin Cowling&nbsp

    Composición mineral del músculo longissimus crudo derivado de canales bovinas producidas y clasificadas en Venezuela Mineral composition of raw longissimus muscle derived from beef carcasses produced and graded in Venezuela.

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    RESUMEN. Se categorizaron por el sistema oficial venezolano en práctica, 145 canales bovinas derivadas de ganado de sacrificio, producido bajo condiciones tropicales en diferentes zonas del país. Muestras del lomo (músculo longissimus dorsi), desprovistas de grasa circundante, se procesaron para el análisis espectrofotométrico, a fin de conocer la variación del contenido de cenizas, macro y microminerales, de acuerdo a la categoría oficial en canal. El análisis de varianza no reveló efecto (P0,10) a elevarse, conforme iba disminuyendo la calidad de la canal, de la categoría AA a la categoría C. Se obtuvieron medias ± desviación estándares generales para porcentaje de cenizas (1.06 ± 0.16) y contenido individual (mg/100g) de Ca (2.77 ± 1.57), Mg (21.62 ± 3.11), P (211.4 ± 35.89), Na (76.06 ± 30.88), K (243.81 ± 63.93), Fe (1.93 ± 0.58), Zn (4.13 ± 0.82), Cu (0.084 ± 0.041) y Mn (0.026 ± 0.016). Se concluye que en esta muestra de ganado tropical venezolano, la variación observada en composición mineral del músculo longissimus no puede ser atribuida a la categoría en canal.SUMMARY. A total of 145 beef carcasses derived from cattle produced under tropical conditions in different regions of Venezuela were graded by the current grading system. Rib (longissimus) samples were excised, trimmed to zero fat cover and subjected to spectrophotometric analyses to examine the variation in ash, macro- and micro-mineral contents, according to the beef carcass grade. The analysis of variance indicated that the Venezuelan carcass grade did not affect significantly the ash or individual mineral content of the raw longissimus muscle; only the Na content tended to decrease (P<0.10) as the beef carcass quality decreased from grade AA to grade C. Overall means ± standard deviations are given for ash percentage (1.06 ± 0.16) and content (mg/100g) of Ca (2.77 ± 1.57), Mg (21.62 ± 3.11), P (211.4 ± 35.88), Na (76.06 ± 30.88), K (243.81 ± 63.93), Fe (1.93 ± 0,58), Zn (4.13 ± 0.82), Cu (0.084 ± 0.041) and Mn (0.026 ± 0.016). It was concluded that the variation in mineral composition of beef longissimus observed for this sample of tropical beef cattle, cannot be attributed to the Venezuelan carcass grade

    Aminoacidophathies, Disorders of

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