Brazilian elections: voting for a scaling democracy

The proportional elections held in Brazil in 1998 and 2002 display identical statistical signatures. In particular, the distribution of votes among candidates includes a power-law regimen. We suggest that the rationale behind this robust scaling invariance is a multiplicative process in which the voter's choice for a candidate is governed by a product of probabilities.Comment: 4 pages, 2 figure

Is the underwater gliding test a valid procedure to estimate the swimmers’ drag?

The aim of this study was to develop a structural equation model for underwater gliding distance based on its determinant variables, in order to confirm whether it is an informative test of young swimmers’ hydrodynamic profile. Methods: Twenty-three subjects (twelve boys and eleven girls with a mean age of 13.61 ± 0.83 years old) were evaluated. The following were determined: (i) the underwater gliding distance; (ii) the squat jump performance; (iii) the passive drag; (iv) the passive drag coefficient; (v) the trunk transverse surface area and; (vi) the gliding velocity. Results: The underwater gliding distance was significantly correlated with the squat jump (rs = 0.47; p = 0.038) and with the coefficient of passive drag (rs = -0.55; p < 0.01) but not with passive drag (rs = 0.41; p = 0.09). The overall model explained 45% of the underwater gliding distance (x2/df = 3.138). Conclusion: The underwater gliding distance seems to be more dependent from the squat jump than from the passive drag. Therefore it seems as if the underwater gliding test is not representative of the swimmers’ passive drag or his /her passive drag coefficient

Pressure-induced Phase Transitions In Linh4so4

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Raman spectra of LiNH4SO4 in frequency range from 600 to 1200 cm-1 were measured from atmospheric pressure up to a pressure at 82 kbar. Two distinct phases are identified in the ranges below 13 kbar (phase) and above 35 kbar (phase). In the range between 13 and 35 kbar the spectrum changes qualitatively in a continuous manner, both as a function of time for fixed pressure and as a function of pressure when the latter is rapidly changed. The results suggest a dynamical reorientation of the SO4 2- ions taking place in this pressure interval. © 1988 The American Physical Society.37422622265CAPES; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; CNPq; Coordenação de Aperfeiçoamento de Pessoal de Nível SuperiorConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq

How informative are the vertical buoyancy and the prone gliding tests to assess young swimmers hydrostatic and hydrodynamic profiles?

The aim of this research was to develop a path-flow analysis model to highlight the relationships between buoyancy and prone gliding tests and some selected anthropometrical and biomechanical variables. Thirty-eight young male swimmers (12.97 ± 1.05 years old) with several competitive levels were evaluated. It were assessed the body mass, height, fat mass, body surface area, vertical buoyancy, prone gliding after wall push-off, stroke length, stroke frequency and velocity after a maximal 25 [m] swim. The confirmatory model included the body mass, height, fat mass, prone gliding test, stroke length, stroke frequency and velocity. All theoretical paths were verified except for the vertical buoyancy test that did not present any relationship with anthropometrical and biomechanical variables nor with the prone gliding test. The good-of-fit from the confirmatory path-flow model, assessed with the standardized root mean square residuals (SRMR), is considered as being close to the cut-off value, but even so not suitable of the theory (SRMR = 0.11). As a conclusion, vertical buoyancy and prone gliding tests are not the best techniques to assess the swimmer’s hydrostatic and hydrodynamic profile, respectively

Young swimmers’ kinematic and hydrodynamic detraining between a two seasons’ break

Young swimmers usually have sever-al weeks of school break in the sum-mer. During such period no swim training is conducted until the begin-ning of the next season. According to training principles, the prolonged absence of a regular ex-ternal load may decrease the form status built up in a previous training period. Since the major focus of swim training in children is their technical enhancement, it is ex-pected that some adaptations will occur namely in kinematics and hy-drodynamic outcomes.info:eu-repo/semantics/publishedVersio

Desarrollo del sistema de información sobre el litoral y el medio marino de la red de información ambiental de Andalucía (REDIAM)

El Subsistema de Información del Litoral y el Medio Marino (SSLyMM) surge por la necesidad de reconversión de un proyecto, el SIGLA, previamente desarrollado de forma conjunta por la Universidad de Sevilla y las Consejerías de Medio Ambiente y Obras Públicas y que habría de ser transformado en un sistema integrado en la REDIAM que vinculara la información sobre litoral y medio marino con los otros subsistemas que configuran esta red (biodiversidad, clima, humedales, etc.), garantizando la actualización permanente y conjunta de los datos, considerando todos los estándares que fijan las nuevas directrices europeas. Con ello, el subsistema debe alcanzar su objetivo de normalización, metadatado y puesta en explotación de la información espacializada relativa a estos medios, dando así cobertura a la estrategia de Gestión Integrada de Zonas Costeras (GIZC), empleando para ello diversas herramientas SIG, de generación de servicios OGC y de integración en web.The Coastal and Marine Environment Subsystem (SSLyMM) has arise by the need of rationalization from a previous project, the SIGLA, which was developed between the University of Sevilla and the Regional Governments in Environment and Works in Andalusia. The SIGLA must be transformed in an integrated system in the REDIAM (Red de Información Ambiental de Andalucía) capable to link spatial coastal and marine data with others subsystems that shape this network (biodiversity, climatology, wetlands, etc.) guaranteeing a continuous and joint updating, and taking into account the grounds from the last european directives. So, the subsystem must achieve the aim of normalization, metadata production and exploitation relating to spatial information in those environments, giving coverage, in this way, to the ICZM strategy (Integrated Coastal Zone Management). With that purpose, it is putting in practice several SIG tools, OGC services generators and web applications

Synthesis, in vitro antiproliferative and anti-mycobacterium tuberculosis activities of novel β-carboline derivatives

A series of β-carboline derivatives with amino or guanidinium were synthesized and evaluated in vitro against anti-Mycobacterium tuberculosis and for antiproliferative activities against nine human cancer cell lines. The compounds 1-(4-hydroxyphenyl)-3-carboxamide(ethylamine) β-carboline (24.9 μg mL-1) and 1-(4-methoxyphenyl)-3-carboxamide(ethylamine) β-carboline (26.9 μg mL-1) were the most active against M. Tuberculosis (MTB). Compounds 1-(4-hydroxyphenyl)-3-carboxamide(ethylamine) β-carboline and 1-(4-methoxyphenyl)-3-carboxamide(propylamine) β-carboline, which had the same substituted groups, inhibited the growth of all human tumor cell lines with growth inhibitory activity (GI50) values from 1.37 to 9.20 mmol L-1. Also in this series, compounds 1-(4-hydroxyphenyl)-3-carboxamide(propylamine) β-carboline and 1-(3-nitrophenyl)-3-carboxamide(propylamine) β-carboline demonstrated significant activity against NCI/ADR cells. Among compounds with a terminal guanidine group, compounds 1-(4-hydroxyphenyl)-3-carboxamide(ethyl)guanidine β-carboline (27.8 μg mL-1) and 1-(3-nitrophenyl)-3-carboxamide(ethyl) guanidine β-carboline (37.4 μg mL-1) demonstrated the greatest activity against MTB. Additionally, compounds 1-(4-methoxyphenyl)-3-carboxamide(ethyl)guanidine β-carboline (GI50 = 0.45 mmol L-1) effectively inhibited growth and was highly selective against NCI/ADR. The in silico study revealed that 1-(4-hydroxyphenyl)-3-carboxamide(ethylamine) β-carboline, 1-(4-methoxyphenyl)-3-carboxamide(ethylamine) β-carboline, 1-(4-hydroxyphenyl)-3-carboxamide(propylamine) β-carboline, 1-(4-methoxyphenyl)-3-carboxamide(propylamine) β-carboline and 1-(3-nitrophenyl)-3-carboxamide(propylamine) β-carboline compounds follow the rules established by Lipinski, suggesting that this compound has no problems with oral bioavailability.27813981405CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQCOORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPESSem informaçãoSem informaçã

Synthesis, In Vitro Antiproliferative And Anti-mycobacterium Tuberculosis Activities Of Novel β-carboline Derivatives

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)A series of β-carboline derivatives with amino or guanidinium were synthesized and evaluated in vitro against anti-Mycobacterium tuberculosis and for antiproliferative activities against nine human cancer cell lines. The compounds 1-(4-hydroxyphenyl)-3-carboxamide(ethylamine) β-carboline (24.9 μg mL-1) and 1-(4-methoxyphenyl)-3-carboxamide(ethylamine) β-carboline (26.9 μg mL-1) were the most active against M. Tuberculosis (MTB). Compounds 1-(4-hydroxyphenyl)-3-carboxamide(ethylamine) β-carboline and 1-(4-methoxyphenyl)-3-carboxamide(propylamine) β-carboline, which had the same substituted groups, inhibited the growth of all human tumor cell lines with growth inhibitory activity (GI50) values from 1.37 to 9.20 mmol L-1. Also in this series, compounds 1-(4-hydroxyphenyl)-3-carboxamide(propylamine) β-carboline and 1-(3-nitrophenyl)-3-carboxamide(propylamine) β-carboline demonstrated significant activity against NCI/ADR cells. Among compounds with a terminal guanidine group, compounds 1-(4-hydroxyphenyl)-3-carboxamide(ethyl)guanidine β-carboline (27.8 μg mL-1) and 1-(3-nitrophenyl)-3-carboxamide(ethyl) guanidine β-carboline (37.4 μg mL-1) demonstrated the greatest activity against MTB. Additionally, compounds 1-(4-methoxyphenyl)-3-carboxamide(ethyl)guanidine β-carboline (GI50 = 0.45 mmol L-1) effectively inhibited growth and was highly selective against NCI/ADR. The in silico study revealed that 1-(4-hydroxyphenyl)-3-carboxamide(ethylamine) β-carboline, 1-(4-methoxyphenyl)-3-carboxamide(ethylamine) β-carboline, 1-(4-hydroxyphenyl)-3-carboxamide(propylamine) β-carboline, 1-(4-methoxyphenyl)-3-carboxamide(propylamine) β-carboline and 1-(3-nitrophenyl)-3-carboxamide(propylamine) β-carboline compounds follow the rules established by Lipinski, suggesting that this compound has no problems with oral bioavailability. © 2016 Sociedade Brasileira de Química.27813981405CAPES, Coordenação de Aperfeiçoamento de Pessoal de Nível SuperiorCNPq, Conselho Nacional de Desenvolvimento Científico e TecnológicoCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq

Variability in young swimmer’ performance and its determinant factors: a two-year follow-up

Predicting sports performance and identifying talented athletes at early ages seems to be a challenging task for practioners and researchers. Based on this, the follow-up of individual pathway to exper?se should be a regular procedure among sports practioners.info:eu-repo/semantics/publishedVersio

Estudo da Sensibilização aos Aeroalergenos Phl p 1, Phl p 5, Ole e 1 e Ole e 2 em Doentes com Patologia Alérgica Sazonal

Introdução: A sensibilização aos pólenes depende de vários factores nomeadamente do tipo de vegetação local e sabe-se que a sintomatologia não está apenas associada à exposição aos pólens mas também a partículas, algumas das quais resultantes da rotura dos grãos de pólen sendo posteriormente aerossolizadas. Objectivos: Relacionar a sensibilização de doentes com a concentração polínica atmosférica e a concentração de alguns dos respectivos aerolergenos. Métodos: Das consultas externas de Imunoalergologia dos hospitais de Évora e Elvas seleccionaram-se doentes que apresentavam queixas sazonais de rinite alérgica e asma brônquica, aos quais foram realizados testes cutâneos em Prick, standardizados, aos pólenes identificados na região. A 55 doentes foram realizados testes ao extracto de Phleum, aos seus alergénios Phl p 1 e Phl p 5, bem como aos extractos das restantes gramíneas e a 47 doentes foram realizados testes ao extracto de Olea, aos seus alergénios Ole e 1 e Ole e 2. Monitorizaram-se diariamente as partículas polínicas e os aeroalergenos mediante 2 colectores específicos para cada tipo. Resultados: A percentagem de doentes que é sensível aos 3 extractos de Phleum (Phleum total, Phl p 1 e Phl p 5) é de 51% , a dos que são sensíveis aos extractos de Phleum total e Phl p 1 é de 16 % e a dos que são sensíveis a Phleum total e Phl p5 é de 2%. A percentagem de doentes que é sensível a somente um dos extractos é de 20% e os que não têm qualquer sensibilidade são 11%. A percentagem de doentes que é sensível aos 3 extractos de Olea (Olea total, Ole e 1 e Ole e 2) é de 23%, a dos que são sensíveis à Olea total e Ole e 1 é de 21 % e a dos que são sensíveis à Olea total e Ole e 2 é de apenas 4%. A percentagem dos que são sensíveis a um dos extractos é de 19% e a dos que não apresentaram qualquer sensibilidade é de 32%. Conclusões: Podemos concluir que 89% dos doentes mostraram ser sensíveis aos alergénios da gramínea Phleum pratense pois mostraram positividade tanto ao extracto de Phleum e/ou aos seus alergénios Phl p 1 e Phl p 5. Em relação à oliveira, 44% dos doentes são alérgicos a este pólen pois são sensíveis ao seu alergénio major, Ole e 1. Em ambos os casos estão correlacionados com os aeroalergenos detectados nas amostras de ar, sendo a sensibilidade aos pólenes de gramíneas maior que a sensibilidade ao pólen de oliveira. Mais estudos devem ser realizados para despiste de reacções cruzadas nomeadamente quanto à Olea com outras plantas da região