Two new species of Synidotea (Crustacea, Isopoda, Valvifera) from Brazil

No presente trabalho são descritas duas novas espécies de isópodes marinhos pertencentes ao gênero Synidotea Harger, 1878, i.e., Synidotea littoralis sp. n. e Synidotea brunnea sp. n.. As espécies foram coletadas nos Estados de Alagoas (S. littoralis sp. n.), Bahia e Espírito Santo (S. brunnea sp. n.), entre algas, na região entre-marés.Two new species of marine isopods referred to the genus Synidotea Harger, 1878, are described from Brazil. The species are Synidotea littoralis sp. n. and Synidotea brunnea sp. n. Both species were collected in the intertidal zone, from amongst seaweeds

Biodegradation of bisphenol A and bisphenol S by labrys portucalensis strain F11

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Resveratrol affects differently rat liver and brain mitochondrial bioenergetics and oxidative stress in vitro: Investigation of the role of gender

Resveratrol (3,5,40-trihydroxy-trans stilbene) is commonly recognized by its antioxidant properties. Despite its beneficial qualities, the toxic effects of this natural compound are still unknown. Since mitochondria are essential to support the energy-dependent regulation of several cell functions, the objective of this study was to evaluate resveratrol effects on rat brain and liver mitochondrial fractions from male and females regarding oxidative stress and bioenergetics. No basal differences were observed between mitochondrial fractions from males and females, except in liver mitochondria, the generation of H2O2 by the respiratory chain is lower for female preparations. Resveratrol inhibited lipid peroxidation in preparations from both genders and organs. Furthermore, brain mitochondria in both gender groups appeared susceptible to resveratrol as seen by a decrease in state 3 respiration and alterations in mitochondrial membrane potential fluctuations during ADP phosphorylation. As opposed, liver mitochondria were less affected by resveratrol. Our data also demonstrates that resveratrol inhibits complex I activity in all mitochondrial preparations. The results suggest that brain mitochondria appear to be more susceptible to resveratrol effects, and gender appears to play a minor role. It remains to be determined if resveratrol effects on brain mitochondria contribute to deterioration of mitochondrial function or instead to mediate hormesis-mediated events.This work is supported by PTDC/AGR-ALI/108326/2008 to M.S.S. from the Portuguese Foundation for Science and Technology, FEDER/ Compete/National Funds. A.C.M., A.M.S. and V.A.S. are recipient of SFRH/BD/33892/2009, SFRH/BD/76086/2011 and SFRH/BPD/ 31549/2006 fellowships, respectively

Analysis of entrepreneurial propensity of students from the Viseu pole of Portuguese Catholic University

Este artigo pretende mostrar a importância do ensino superior na promoção do empreendedorismo. Assim, começa-se com uma análise teórica dos conceitos de empreendedorismo e de empreendedor e dos principais motivos que conduzem ao empreendedorismo, bem como dos obstáculos que o dificultam. Salienta-se também a importância que o ensino superior tem na promoção do empreendedorismo. Faz-se, por fim, uma breve evolução histórica da educação para o empreendedorismo no ensino superior e do que tem sido feito em Portugal nesta área. Em termos metodológicos, apresentam-se os resultados de um estudo efetuado com 348 alunos do Pólo de Viseu da Universidade Católica Portuguesa. Este estudo teve como principal objetivo conhecer a propensão empreendedora dos seus alunos. Os resultados obtidos neste estudo sugerem que os alunos têm pouca tendência empreendedora, o que se poderá dever aos receios e às dificuldades em desenvolver um negócio próprio, assim como a alguns fatores que condicionam a criação e o sucesso de uma empresa. Assim, é fundamental evidenciar a importância do empreendedorismo, quer para os indivíduos, quer para a sociedade, e, por isso, é indispensável fomentar a sua promoção, sobretudo junto da comunidade escolar.This article aims to show the importance of higher education in promoting entrepreneurship. So, we start with a theoretical analysis of the concepts of entrepreneurship and entrepreneur and the main reasons that lead to entrepreneurship, such as the obstacles to it. Also highlight the importance that higher education has to promote entrepreneurship, and, finally, a brief historical development of entrepreneurship education in higher education and what has been done in this area in Portugal. In methodological terms, we present the results of a study conducted with 348 students from Viseu pole of the Portuguese Catholic University. This study aimed to know the entrepreneurial propensity of their students. The results of this study suggest that students have little entrepreneurial trend, which could be due to the fears and difficulties in developing their own business, as well as some factors that influence the creation and success of a company. Thus, it is crucial to highlight the importance of entrepreneurship, both for individuals and for society, and therefore it is essential to foster its promotion especially among the school community.info:eu-repo/semantics/publishedVersio

Sulfide oxidation by heterotrophic P. Koreensis A9 under aerobic conditions

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Overview of stimuli-responsive mesoporous organosilica nanocarriers for drug delivery

The application of nanomaterials is regarded nowadays as a highly promising approach for overcoming the limitations of the currently available cancer treatments, contributing for the creation of more effective, precise, and safer therapies. In the last years, organosilica nanoparticles arisen as alternatives to the most common mesoporous silica nanoparticles. The organosilica nanoparticles combine the advantages of the mesoporous silica, such as structural stability and mesoporous structure, with the increased biocompatibility and biodegradability of organic materials. Therefore, the variety of organic bridges that can be incorporated into the silica matrix allowed the development of new and exciting compositions, properties, and functions for improving the therapeutic effectiveness of the anticancer nanomedicines. In this review, the strategies that have been explored to create stimuli-responsive organosilica-based drug delivery systems are highlighted, describing the practical approaches and mechanisms controlling the drug release. Additionally, the organosilica nanoparticles surface modifications aimed for increasing the blood circulation time and the tumor targeting are also described.info:eu-repo/semantics/publishedVersio