The National Health Insurance Bill: Responses and options for the Portfolio Committee on Health

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The effect of trepanning speed of laser drilled acute angled cooling holes on the high temperature low cycle corrosion fatigue performance of CMSX-4 at 850 °C

The effect of laser trepanning speed and, as a result, recast layer thickness on the high temperature corrosion fatigue behaviour of CMSX-4 superalloy acute angled holes was investigated. The experimental test results show that an increasing laser drilling speed caused a reduction in corrosion fatigue life by 35–50% at 850 °C, under low cycle fatigue regime. This reduction was found to correlate directly with the recast layer thickness and surface anomalies within the recast layer produced during the laser drilling process. Corrosion had a smaller effect on the overall life of the laser drilled specimens under the conditions tested. The results presented show that laser trepanning speed is influential in limiting the life performance of laser drilled components in service

The Competition Commission Health Market Inquiry Report: An overview and key imperatives

The Competition Commission’s Health Market Inquiry (HMI) is the most systematic and comprehensive investigation carried out into the South African private health sector. The recommendations as set out in the HMI Final Report merit extensive discussion and debate, as they could – if implemented – have far-reaching consequences for the future of the healthcare system. The objective of this article is to contribute to this discussion by providing an overview of the key findings and recommendations of the HMI and highlighting the resultant key imperatives at this critical juncture of policy development

Online on-board Optimization of Cutting Parameter for Energy Efficient CNC Milling

Energy efficiency is one of the main drivers for achieving sustainable manufacturing. Advances in machine tool design have reduced the energy consumption of such equipment, but still machine tools remain one of the most energy demanding equipment in a workshop. This study presents a novel approach aimed to improve the energy efficiency of machine tools through the online optimization of cutting conditions. The study is based on an industrial CNC controller with smart algorithms optimizing the cutting parameters to reduce the overall machining time while at the same time minimizing the peak energy consumption

Burkholderia cepacia complex and limited cutaneous vasculitis in patients with cystic fibrosis : a case series

There is a high association of reactive skin presentations, mainly limited cutaneous vasculitis in patients with cystic fibrosis and Burkholderia cepcia complex chronic infection. This may be due to raised levels of circulating inflammatory mediators.Publisher PDFPeer reviewe

First-principle study of excitonic self-trapping in diamond

We present a first-principles study of excitonic self-trapping in diamond. Our calculation provides evidence for self-trapping of the 1s core exciton and gives a coherent interpretation of recent experimental X-ray absorption and emission data. Self-trapping does not occur in the case of a single valence exciton. We predict, however, that self-trapping should occur in the case of a valence biexciton. This process is accompanied by a large local relaxation of the lattice which could be observed experimentally.Comment: 12 pages, RevTex file, 3 Postscript figure

Legal and ethical requirements for developing a medical MOOC: Lessons learnt from the Paediatric Physical Examination Skills MOOC

Massive open online courses (MOOCs) are increasingly being integrated into medical education. The production of a MOOC demonstrating physical examinations of children raised the issue of legal and ethical consent for the use of images and video-recordings of children. The present article shares the valuable lessons we learned around the legal and ethical consent required, and the operational issues that will be essential to comply with these legal and ethical considerations. This information may be valuable to other educators, especially those in similar resource-constrained settings,who are planning to create medical MOOCs

Data Mining and Knowledge Reuse for the Initial Systems Design and Manufacturing: Aero-engine Service Risk Drivers

Service providers of civil aero engines are typically confronted with a high cost of maintenance, replacement and refurbishment of the service damaged components. In such context, service experience becomes a key issue for determining the service risk drivers for operational disruptions and maintenance burden. This paper presents an industrial case study to produce new knowledge on the relationships between degradation and component design to manufacture. The study applied semantic data mining as a methodology for an efficient and the consistent data capture, representation, and analysis. The paper aims at identifying the service risk drivers based on service experience and event data. The analysis shows that the 3 top mechanisms accounting for 32% of the mechanism references have a strong Pareto effect. The paper concludes with missing information links and future research directions

A mixed methods and triangulation model for increasing the accuracy of adherence and sexual behaviour data: the Microbicides Development Programme.

Background: The collection of accurate data on adherence and sexual behaviour is crucial in microbicide (and other HIV-related) research. In the absence of a "gold standard" the collection of such data relies largely on participant self-reporting. After reviewing available methods, this paper describes a mixed method/triangulation model for generating more accurate data on adherence and sexual behaviour in a multi-centre vaginal microbicide clinical trial. In a companion paper some of the results from this model are presented [1].Methodology/Principal Findings: Data were collected from a random subsample of 725 women (7.7% of the trial population) using structured interviews, coital diaries, in-depth interviews, counting returned gel applicators, focus group discussions, and ethnography. The core of the model was a customised, semi-structured in-depth interview. There were two levels of triangulation: first, discrepancies between data from the questionnaires, diaries, in-depth interviews and applicator returns were identified, discussed with participants and, to a large extent, resolved; second, results from individual participants were related to more general data emerging from the focus group discussions and ethnography. A democratic and equitable collaboration between clinical trialists and qualitative social scientists facilitated the success of the model, as did the preparatory studies preceding the trial. The process revealed some of the underlying assumptions and routinised practices in "clinical trial culture" that are potentially detrimental to the collection of accurate data, as well as some of the shortcomings of large qualitative studies, and pointed to some potential solutions.Conclusions/Significance: The integration of qualitative social science and the use of mixed methods and triangulation in clinical trials are feasible, and can reveal (and resolve) inaccuracies in data on adherence and sensitive behaviours, as well as illuminating aspects of "trial culture" that may also affect data accuracy