Analysis of the Historical Settlements of the Giralda

The preservation of the cultural heritage is a current challenge for modern societies. Thus, it is important to analyse the structural behaviour of historical buildings in order to detect and prevent future damage. This paper analyses the historical settlements of the Giralda tower of the Cathedral of Seville. Currently, it has a tilt which might have been caused by a differential settlement. With this aim, a detailed characterisation of the foundation and its geotechnical model has been carried out. An accurate 3D Finite Elements Model (FEM) has been used to analyse the settlements, taking into account the different construction phases, the loads, the time of execution and consolidation between phases. Finally, the 3D FEM results have been compared with other previous works and the in-situ measurements of the verticality of the tower. Therefore, the authors have found that the tilt to the south-east direction has been caused by the thicker, soft strata under this corner, which has caused differential settlement in this direction. Moreover, it should be highlighted that a good agreement between the settlements of the model and its real top displacements has been obtained

Self-report prevalence and associated factors to drug hypersensitivity in Mexican young adults

Background: Drug hypersensitivity is defined as any unfavorable reaction that occurs after the administration of any drug. It may or may not be mediated by the involvement of the immune system. Epidemiological data related to drug hypersensitivity reactions in our country are scarce. Objective: To determine the prevalence of drug hypersensitivity in a group of young adults, as well as to identify associated factors. Methods: A structured questionnaire was applied to young people aged 18 to 25 years. The instrument was oriented to identify reactions of drug hypersensitivity, as well as the most prevalent drugs involved. In addition, a personal and family history of atopic diseases was included. Analysis for associations between variables was been done through logistic regression. Results: The prevalence of drug hypersensitivity reactions was 12% (144 of 1,200). The antibiotics were the agents most related to hypersensitivity reactions (9.8%) followed by nonsteroidal anti-inflammatory drugs (1.6%). Factors associated with drug hypersensitivity were a personal history of asthma, odds ratio (OR) 3.15 (95% confidence interval [CI], 1.44–6.91), maternal and paternal history of drug hypersensitivity, OR 2.33 (95% CI, 1.21–4.48) and OR 3.11 (95% CI, 1.22–7.92), respectively. Conclusion: The results of this research show that drug hypersensitivity in young adults is a highly prevalent event and it is associated with personal history of asthma and history of drug hypersensitivity in parents

Aplicación de dispositivos móviles para la monitorización y seguimiento de pacientes con hipertensión arterial polimedicados y diabetes mellitus insulinodependiente con factores de riesgo

Las enfermedades cardiovasculares son la primera causa de muerte en personas mayores de 45 años en el mundo, por lo que es necesaria la implementación de actividades e intervenciones que contribuyan a la detección, diagnóstico temprano y seguimiento ambulatorio adecuado de estos padecimientos.Dentro del propósito más importante de este trabajo, es detectar y realizar un seguimiento adecuado a estos usuarios diagnosticados, a través de diferentes vías y estrategias de captación y control, con el objetivo de realizar un plan terapeútico adecuado de acuerdo a los factores de riesgo identificados

Effects of dietary polyunsaturated fatty acid sources on expression of lipid-related genes in bovine milk somatic cells

© 2020, The Author(s). The objective of this study was to compare the effect of contrasting sources of dietary n-6 and n-3 PUFA on expression of genes related to lipid metabolism in dairy cows. During 63days, fifteen lactating cows were assigned to a control or basal diet containing no added lipid (n = 5 cows); and treatment diets supplemented with SO (n = 5 cows; unrefined soybean oil; 2.9% of DM) or FO (n = 5 cows; fish oil manufactured from salmon oil; 2.9% of DM). Plasma for fatty acid (FA) analysis and milk somatic cells (MSC) were obtained from all cows at the beginning of the study (day 0) and on days 21, 42 and 63. Plasma was used to determine FA transport dynamics. Compared with control and FO, plasma from SO had increased contents of C18:1 cis-9, C18:1 trans-11, C18:2 cis-9, trans-11 and total monounsaturated FA. On the other hand, compared with control and SO, FO increased plasma contents of C20:3 n-3, C20:3 n-6, C20:4 n-6, C20:5 n-3, C22:6 n-3 and total polyunsaturated FA. Moreover, plasma C18:3 n-3 and C20:5 n-3 increased over time for all diets. Compared with control, SO downregulated ACACA, INSIG1, and DGAT1, whereas FO downregulated ACACA, PPARGC1, LPIN1 and FABP3 on day 63, in MSC. At different time-points, SO and FO downregulated genes related to synthesis and intracellular transport of FA, synthesis of triglycerides, and transcription factors

Effects of dietary vegetable oils on mammary lipid-related genes in holstein dairy cows

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Comparative analysis between the Spanish and Portuguese seismic codes. Application to a border RC primary school

The Iberian Peninsula is close to the Eurasia-Africa plate boundary resulting in a considerable seismic hazard. In fact, the southwestern Iberian Peninsula is affected by far away earthquakes of long-return period with large-very large magnitude. A project named PERSISTAH (Projetos de Escolas Resilientes aos SISmos no Território do Algarve e de Huelva, in Portuguese) aims to cooperatively assess the seismic vulnerability of primary schools located in the Algarve (Portugal) and Huelva (Spain). Primary schools have been selected due to the considerable amount of similar buildings and their seismic vulnerability. In Portugal, the Decreto Lei 235/83 (RSAEEP) is mandatory while in Spain, the mandatory code is the Seismic Building Code (NCSE-02). In both countries, the Eurocode-8 (EC-8) is recommended. Despite the fact that both regions would be equally affected by an earthquake, both seismic codes are significantly different. This research compares the seismic action of Ayamonte (Huelva) and Vila Real de Santo António (Portugal). Both towns are very close and located at both sides of the border. Moreover, they share the same geology. This analysis has been applied considering a RC primary school building located in Huelva. To do so, the performance-based method has been used. The seismic action and the damage levels are compared and analysed. The results have shown considerable differences in the seismic actions designation, in the performance point values and in the damage levels. The values considered in the Portuguese code are significantly more unfavourable. An agreement between codes should be made for border regions.This work has been supported by the INTERREG-POCTEP Spain-Portugal programme and the European Regional Development Fund through the 0313_PERSISTAH_5_P project and the VI-PPI of the University of Seville by the granting of a scholarship. The grant provided by the Instituto Universitario de Arquitectura y Ciencias de la Construcción is acknowledged.info:eu-repo/semantics/publishedVersio

Practical guide for earthquake resilient schools

This guide is intended to be a resource, and not a manual, for increasing the resilience of an educational community, by showing the community what they can do on their own account and how they can strengthen their ability to handle seismic risk (for example, being informed and familiarised with the characteristics that affect the vulnerability of an area in the event of an earthquake, and prepared to protect the students under their tutelage before the earth shakes).POCTEP-INTERREG España-Portugal e Fundo Europeu de Desenvolvimento Regional (FEDER); 0313_PERSISTAH_5_P, Projetos de Escolas Resilientes aos Sismos no Território do Algarve e de Huelvainfo:eu-repo/semantics/publishedVersio

Effect of feeding cows with unsaturated fatty acid sources on milk production, milk composition, milk fatty acid profile, and physicochemical and sensory characteristics of ice cream

Simple Summary: The objective of this study was to evaluate the effects of supplementation of dairy cows' diets with different fatty acid (FA) sources on milk production, milk composition, milk fatty acid profile, and physicochemical and sensory characteristics of ice cream. Supplementation (3% dry matter (DM)) of diets with soybean oil (SO) and fish oil (FO) did not have detrimental effects on milk production, milk composition, or ice cream physicochemical and sensory characteristics. From a human standpoint, SO and FO improved the FA profile of milk. Abstract: The objective of this study was to evaluate the effects of supplementation of dairy cows with different fatty acid sources (soybean oil (SO) and fish oil (FO)) on milk production, milk composition, milk fatty acid profile, and physicochemical and sensory characteristics of ice cream. During 63 days, fifteen Holstein cows averaging 198 ± 35 days in milk were assigned to three groups: control diet with no added lipid (n = 5 cows); and supplemented diets with SO (n = 5 cows; unrefined SO; 30 g/kg DM) or FO (n = 5 cows; FO from unrefined salmon oil; 30 g/kg DM). Milk production, milk fat, and milk protein were not affected by treatments. Saturated fatty acids in milk fat were decreased with SO and FO compared with control. C18:2 cis-9, cis-12 was increased with SO whereas C18:2 cis-9, trans-11, C20:3n-3, C20:3n-6, C20:5n-3, and C22:6n-3 were the highest with FO. Draw temperature and firmness were higher in SO compared to control and FO ice creams. Melting resistance was higher in FO compared with control and SO ice creams. Supplementation of cow diets with SO and FO did not have detrimental effects on milk production, or ice cream physicochemical and sensory characteristics

Effect of soybean oil and fish oil on lipid-related transcripts in subcutaneous adipose tissue of dairy cows

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