Transnational Nationalists: Cosmopolitan Women, Philanthropy, and Italian State-Building, 1850-1890

“Transnational Nationalists: Cosmopolitan Women, Philanthropy and Italian State-Building, 1850-1890” is a study of Protestant and Jewish transnational reforming women who took advantage of a period of fluidity to act as non-state actors and impact Italian unification and liberation, a process known as the Risorgimento, and subsequent Italian state-building. Inspired by Giuseppe Mazzini’s spiritual brand of romantic cosmopolitan nationalism, as well as Giuseppe Garibaldi’s military campaigns, and believing that women had a god-given duty to provide education, morality, and uplift to oppressed groups, they worked to provide Italy not only with physical unification but also moral regeneration. Through an examination of their published and private works, I analyze how they publicized, fundraised, and conspired for the Risorgimento, and how they later worked to continue its legacy through biographical works, early childhood education, and the campaign against state-regulated prostitution. Through this, I challenge the boundaries between national and transnational, between the charitable and the political, and between public and private

Alien Registration- Moore, Diana (Topsham, Sagadahoc County)

https://digitalmaine.com/alien_docs/9371/thumbnail.jp

What is the best approach to the evaluation of hirsutism?

The evaluation of hirsutism should begin with a history and physical examination to identify signs and symptoms suggestive of diseases such as polycystic ovarian syndrome (PCOS), hypothyroidism, hyperprolactinemia, hyperandrogenic insulin-resistant acanthosis nigricans (HAIR-AN) syndrome, androgenic tumors, Cushing's syndrome, or congenital adrenal hyperplasia (CAH). Findings suggestive of these diseases include rapid or early-onset hirsutism, menstrual irregularities, hypertension, severe hirsutism, virilization, or pelvic masses (strength of recommendation [SOR]: B, based on a cohort study in a referral population). Hirsutism with unremarkable history and physical exam findings should be evaluated with a serum total testosterone and dehydroepiandrosterone sulfate (DHEAS) level (SOR: B, based on a cohort study in a referral population)

Finding Hidden Treasures: Research Help in the Library and Archives

At the 2009 Deaf History International Conference, Ulf Hedberg spoke on the preservation of Deaf materials. The objective was to promote the preservation of Deaf materials by individuals, institutions, and organizations and to encourage the donation of Deaf materials to libraries, archives, museums, or organizations. In this chapter our objective is to identify the numerous resources at the Gallaudet University Library Deaf Collections and Archives and the Rochester Institute of Technolo-gy’s (RIT) Wallace Library, which are now on the Internet. The resources discussed here contain biographical materials that relate to this book’s theme of telling Deaf lives. Since the year 2012, when the Eighth Deaf History International conference was hosted, was the three-hundredth anniversary of the Abbé de l’Épée’s birth, several de l’Épée resources are identified. Many of the materials mentioned from the Gallaudet Univer-sity Library Deaf Collections and Archives were made accessible online thanks to a generous grant from the Mellon Foundation

Emerging Technology Tools for Qualitative Data Collection

Emerging technology tools enable qualitative researchers to collect text, audio, and visual data any time and any place. However, given many of these tools are cloud-based, they also present questions regarding security and confidential data collection. The uses, advantages, and drawbacks of emerging technology tools used for note-taking, collecting, managing, and sharing various forms of data will be presented within the context of qualitative data collection in instructional technology

Book Reviews

Book Reviews of: Jerry G. Gaff, General Education Today (Jossey-Bass, 1983) Jeremy Rifkin, Algeny (Viking Press, 1983) Frances Fox Piven and Richard A. Cloward, The New Class War (Pantheon, 1982

Effects of vergence findings on prepresbyopic near spectacle prescriptions

Our study investigated effects of vergence findings on both prepresbyopic and presbyopic near spectacle prescriptions. It is possible that individuals with inadequate convergence abilities, maintain excessive accommodative effort for long periods of time to compensate for the convergence problem. This may result in a greater accommodative amplitude than one would expect based on age alone. If true, perhaps vision therapy programs utilizing sustained positive accommodative techniques, may delay the onset of presbyopia and the need for bifocals or reading glasses. We hypothesize that 36 - 50 year olds with convergence deficits will have larger accommodative amplitudes than an age matched control group. Five hundred forty clinic records were sampled from age 36 - 50 from the Pacific University Family Vision Facilities between October 25, 1998 and January 26, 1999. Data from completed vision examinations were collected and analyzed using the Statview Analysis Systems. A significant correlation was found between age and the add prescription, distance phoria and the add prescription, and the fused cross cylinder and the add prescription. No significant correlation was found between any of the near vergence findings (Base Out, Base In phoria, and NPC) amount of add, however, additional studies are needed to further investigate the role distance phoria plays in the amount of add given to patients

The clinical effectiveness and cost-effectiveness of ablative therapies in the management of liver metastases: systematic review and economic evaluation

Background: Many deaths from cancer are caused by metastatic burden. Prognosis and survival rates vary, but survival beyond 5 years of patients with untreated metastatic disease in the liver is rare. Treatment for liver metastases has largely been surgical resection, but this is feasible in only approximately 20–30% of people. Non-surgical alternatives to treat some liver metastases can include various forms of ablative therapies and other targeted treatments.Objectives: To evaluate the clinical effectiveness and cost-effectiveness of the different ablative and minimally invasive therapies for treating liver metastases.Data sources: Electronic databases including MEDLINE, EMBASE and The Cochrane Library were searched from 1990 to September 2011. Experts were consulted and bibliographies checked.Review methods: Systematic reviews of the literature were undertaken to appraise the clinical effectiveness and cost-effectiveness of ablative therapies and minimally invasive therapies used for people with liver metastases. Studies were any prospective study with sample size greater than 100 participants. A probabilistic model was developed for the economic evaluation of the technologies where data permitted.Results: The evidence assessing the clinical effectiveness and cost-effectiveness of ablative and other minimally invasive therapies was limited. Nine studies of ablative therapies were included in the review; each had methodological shortcomings and few had a comparator group. One randomised controlled trial (RCT) of microwave ablation versus surgical resection was identified and showed no improvement in outcomes compared with resection. In two prospective case series studies that investigated the use of laser ablation, mean survival ranged from 41 to 58 months. One cohort study compared radiofrequency ablation with surgical resection and five case series studies also investigated the use of radiofrequency ablation. Across these studies the median survival ranged from 44 to 52 months. Seven studies of minimally invasive therapies were included in the review. Two RCTs compared chemoembolisation with chemotherapy only. Overall survival was not compared between groups and methodological shortcomings mean that conclusions are difficult to make. Two case series studies of laser ablation following chemoembolisation were also included; however, these provide little evidence of the use of these technologies in combination. Three RCTs of radioembolisation were included. Significant improvements in tumour response and time to disease progression were demonstrated; however, benefits in terms of survival were equivocal. An exploratory survival model was developed using data from the review of clinical effectiveness. The model includes separate analyses of microwave ablation compared with surgery and radiofrequency ablation compared with surgery and one of radioembolisation in conjunction with hepatic artery chemotherapy compared with hepatic artery chemotherapy alone. Microwave ablation was associated with an incremental cost-effectiveness ratio (ICER) of £3664 per quality-adjusted life-year (QALY) gained, with microwave ablation being associated with reduced cost but also with poorer outcome than surgery. Radiofrequency ablation compared with surgical resection for solitary metastases < 3 cm was associated with an ICER of –£266,767 per QALY gained, indicating that radiofrequency ablation dominates surgical resection. Radiofrequency ablation compared with surgical resection for solitary metastases ? 3 cm resulted in poorer outcomes at lower costs and a resultant ICER of £2538 per QALY gained. Radioembolisation plus hepatic artery chemotherapy compared with hepatic artery chemotherapy was associated with an ICER of £37,303 per QALY gained.Conclusions: There is currently limited high-quality research evidence upon which to base any firm decisions regarding ablative therapies for liver metastases. Further trials should compare ablative therapies with surgery, in particular. A RCT would provide the most appropriate design for undertaking any further evaluation and should include a full economic evaluation, but the group to be randomised needs careful selection.Source of funding: Funding for this study was provided by the Health Technology Assessment programme of the National Institute for Health Research