Risk communication approaches for preventing private groundwater contamination in the Republic of Ireland: a mixed-methods study of multidisciplinary expert opinion

The mechanisms of private-well groundwater contamination are uniquely complex, necessitating a multisector communicative approach to risk management, premised on behaviour promotion. In countries such as the Republic of Ireland (ROI), characterised by oftentimes high groundwater contamination risk and concurrently limited user awareness, incorporation of multidisciplinary, ‘expert-based’ knowledge may facilitate design of evidence-based, practical interventions. Expert interviews represent an efficient form of expert consultation, enabling ease of access to niche information and comparison of procedure, but remain under-utilised within the groundwater management literature. In response, the current study elicited opinion from 50 experts across four broad categories (communications, engineering/science, policy, and risk assessment) via a mixed-methods interview study. Semi-structured qualitative interviews were undertaken with experts from the ROI (n = 25) and European/North American countries (n = 25) and examined using thematic (qualitative) and bivariate statistical (quantitative) analyses. Experts noted financial cost, knowledge and social norms as primary barriers to adopting private-groundwater and other health risk-prevention behaviours. Lack of organisational knowledge as a communication barrier was significantly related to expert category (p = 0.034) and highlighted by a majority of communications experts (95%) compared to policy (75%), risk assessment (67%) and engineering/science (50%) experts. The most frequently suggested communication activities comprised events (24%), radio segments (22%), workshops (24%) and community meetings (30%), allied with family-oriented, discursive approaches to information delivery. Study findings may be used by both national (Irish) and international stakeholders in myriad hydrogeological contexts to develop educational outreach strategies and contribute to the existing groundwater-management-knowledge base

Private Groundwater Management and Risk Awareness: A cross-sectional analysis of two age-related subsets in the Republic of Ireland

Risk communication represents the optimal instrument for decreasing the incidence of private groundwater contamination and associated waterborne illnesses. However, despite attempts to promote voluntary well maintenance in high groundwater-reliant regions such as the Republic of Ireland, awareness levels of supply status (e.g. structural integrity) have remained low. As investigations of supply awareness are often thematically narrow and homogeneous with respect to sub-population, revised analyses of awareness among both current and future supply owners (i.e. adults of typical well owner and student age) are necessary. Accordingly, the current study utilised a national survey of well users and an age-based comparison of supply awareness. Awareness was measured among 560 Irish private well users using a multi-domain scoring framework and analysed in conjunction with experiential variables including experience of extreme weather events and previous household infections, and perceived self-efficacy in maintaining supply. Respondents displayed a median overall awareness score of 66.7%, with supply owners (n = 399) and students (n = 161) exhibiting median scores of 75% and 58.3%. Awareness among both combined respondent subsets and well owners was significantly related to gender, well use factors and self-perceived behavioural efficacy while awareness among students was not correlated with any independent variable. Cluster analysis identified three distinct respondent groups characterised by awareness score and gender in both current and future well owner subsets. Male well owners and students displayed higher perceived self-efficacy irrespective of awareness score while female well owners that demonstrated high awareness were significantly more likely to report postgraduate educational (p \u3c 0.001). Findings suggest that recent experience of extreme weather events does not significantly influence supply awareness and mirror previously identified knowledge differences between well owners and young adults

Role of Vascular Endothelial Growth Factor in Bone Marrow Stromal Cell Modulation of Endothelial Cells

One of the fundamental principles that underlies tissue-engineering strategies using cell transplantation is that a newly formed tissue must acquire and maintain sufficient vascularization in order to support its growth. Enhancing angiogenesis through delivery of growth factors is one approach to establishing a vascular network to these tissues. In this study, we tested the potential of bone marrow stromal cells (BMSCs) to modulate the growth and differentiation activities of blood vessel precursors, endothelial cells (ECs), by their secretion of soluble angiogenic factors. The growth and differentiation of cultured ECs were enhanced in response to exposure to BMSC conditioned medium (CM). Enzyme-linked immunosorbent assays demonstrated that both mouse and human BMSCs secreted significant quantities of vascular endothelial growth factor (VEGF) (2.4-3.1 ng/106 cells per day). Furthermore, eliminating the activity of BMSC-secreted VEGF with blocking antibodies completely blocked the CM effects on cultured ECs. These data demonstrate that human BMSCs secrete sufficient quantities of VEGF to enhance survival and differentiation of endothelial cells in vitro, and suggest they may be capable of directly orchestrating angiogenesis in vivo.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/63256/1/107632703762687573.pd

Starting and Sustaining Successful Faculty Development Programs at Small Colleges

This chapter complements a recent chapter in To Improve the Academy by Mooney and Reder (2008) that discusses the distinctive features and challenges of faculty development at small and liberal arts colleges. As a continuation and expansion of that more conceptual discussion, we aim to convey practical strategies for relatively new faculty developers at small institutions with incipient programs. The suggestions offered in this chapter are grounded in our experiences as faculty developers at liberal arts colleges and developed through numerous national conference presentations and conversations with colleagues in the field over the past decade. Although our recommendations are particularly salient for faculty developers working in a small college setting, our ideas should be applicable across institutional types

Endothelial cell modulation of bone marrow stromal cell osteogenic potential

In the context of bone development and regeneration, the intimate association of the vascular endothelium with osteogenic cells suggests that endothelial cells (ECs) may directly regulate the differentiation of osteoprogenitor cells. To investigate this question, bone marrow stromal cells (BMSCs) were cultured: in the presence of EC‐conditioned medium, on EC extracellular matrix, and in EC cocultures with and without cell contact. RNA and protein were isolated from ECs and analyzed by reverse transcriptase‐polymerase chain reaction and Western blotting, respectively, for expression of bone morphogenetic protein 2 (BMP‐2). In animal studies, BMSCs and ECs were cotransplanted into severe combined immunodeficient mice on biodegradable polymer matrices, and histomorphometric analysis was performed to determine the extent of new bone and blood vessel formation. ECs significantly increased BMSC osteogenic differentiation in vitro only when cultured in direct contact. ECs expressed BMP‐2, and experiments employing interfering RNA inhibition confirmed its production as contributing to the increased BMSC osteogenic differentiation. In vivo, cotransplantation of ECs with BMSCs resulted in greater bone formation than did transplantation of BMSCs alone. These data suggest that ECs function not only to form the microvasculature that delivers nutrients to developing bone but also to modulate the differentiation of osteoprogenitor cells in vitro and in vivo.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/154319/1/fsb2fj042529fje-sup-0001.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/154319/2/fsb2fj042529fje.pd

Trolling in asynchronous computer-mediated communication: From user discussions to academic definitions

Whilst computer-mediated communication (CMC) can benefit users by providing quick and easy communication between those separated by time and space, it can also provide varying degrees of anonymity that may encourage a sense of impunity and freedom from being held accountable for inappropriate online behaviour. As such, CMC is a fertile ground for studying impoliteness, whether it occurs in response to perceived threat (flaming), or as an end in its own right (trolling). Currently, first and secondorder definitions of terms such as im/politeness (Brown and Levinson 1987; Bousfield 2008; Culpeper 2008; Terkourafi 2008), in-civility (Lakoff 2005), rudeness (Beebe 1995, Kienpointner 1997, 2008), and etiquette (Coulmas 1992), are subject to much discussion and debate, yet the CMC phenomenon of trolling is not adequately captured by any of these terms. Following Bousfield (in press), Culpeper (2010) and others, this paper suggests that a definition of trolling should be informed first and foremost by user discussions. Taking examples from a 172-million-word, asynchronous CMC corpus, four interrelated conditions of aggression, deception, disruption, and success are discussed. Finally, a working definition of trolling is presented

A Systems Approach to Performance Analysis in Women’s Netball: Using Work Domain Analysis to Model Elite Netball Performance

Netball is a newly professional women’s sport, as such there has been little research conducted investigating performance analysis (PA) in elite netball. The aim of this study was to develop a model of the elite netball performance system to identify the complex relationships among key performance indicators. Eleven elite subject matter experts (SMEs) participated in workshops to produce a systems model of the netball match performance. The model was developed using the work domain analysis (WDA) method. A model of the netball match performance system was produced showing the interrelated objects, processes, functions, values, and purposes involved in elite level netball matches. The model identified the components of elite level netball performance and the interactions and relationships between them. The output of this research has identified novel PA measures including passing and possession measures, measures of cognitive performance, and measures related to physical activity. Netball is a complex sport, involving multiple dynamic and interrelated components. Consequently, there is an opportunity to develop holistic PA measures that focus on interacting components, as opposed to components in isolation

Hydrodynamic characterization of soil compaction using integrated electrical resistivity and X‐ray computed tomography

Modern agricultural practices can cause significant stress on soil, which ultimately has degrading effects, such as compaction. There is an urgent need for fast, noninvasive methods to characterize and monitor compaction and its impact on hydraulic processes. Electrical resistivity tomography (ERT) is a well-established method used for the assessment of soil hydraulic properties due to its high temporal resolution and sensitivity to changes in moisture content and salinity, whereas X-ray computed tomography (CT) can be used for high-spatial-resolution imaging of soil structure. We used the combined strengths of both methods to study soil under three different levels of compaction. The soils were X-ray scanned and electrically monitored after the application of a saline solution to the soil surface. The scans revealed the pore network architecture and allowed us to compute its size and connectivity. The ERT models revealed inhibited percolation rates for soils with a lower bulk density, but also how resistivity changes are spatiotemporally distributed within the soil columns. Furthermore, we obtained a quantitative link between the two methods, by which voxels more densely populated with pores were associated with higher temporal variations in electrical resistivity. Building on this, we established a spatial collocation between pore structure and distribution of solution during percolation. This demonstrates the potential of the combined strengths of the two tomographic methods to obtain an enhanced characterization of soil hydrodynamic properties

Evidence for increased expression of the Amundsen Sea Low over the South Atlantic during the late Holocene

The Amundsen Sea Low (ASL) plays a major role in the climate and environment of Antarctica and the Southern Ocean, including surface air temperature and sea ice concentration changes. Unfortunately, a relative dearth of observational data across the Amundsen and Bellingshausen seas prior to the satellite era (post-1979) limits our understanding of the past behaviour and impact of the ASL. The limited proxy evidence for changes in the ASL are primarily restricted to the Antarctic where ice core evidence suggests a deepening of the atmospheric pressure system during the late Holocene. However, no data have previously been reported from the northern side of the ASL. Here we report a high-resolution, multi-proxy study of a 5000-year-long peat record from the Falkland Islands, a location sensitive to contemporary ASL dynamics which modulates northerly and westerly airflow across the southwestern South Atlantic sector of the Southern Ocean. In combination with climate reanalysis, we find a marked period of wetter, colder conditions most likely the result of enhanced southerly airflow between 5000 and 2500 years ago, suggesting limited ASL influence over the region. After 2500 years ago, drier and warmer conditions were established, implying more westerly airflow and the increased projection of the ASL onto the South Atlantic. The possible role of the equatorial Pacific via atmospheric teleconnections in driving this change is discussed. Our results are in agreement with Antarctic ice core records and fjord sediments from the southern South American coast, and suggest that the Falkland Islands provide a valuable location for reconstructing high southern latitude atmospheric circulation changes on multi-decadal to millennial timescales