516 research outputs found

    Empleo de áridos reciclados en el sector de la construcción: un análisis bibliométrico científico

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    The authors would like to thank Jose Miguel Lao-Egea from “Promoción de Empleo Joven e Implantación de la Garantía Juvenil en I+D+I” of Spanish Ministry for Science Innovation and Universities, the Departments of Building Construction and Civil Engineering and Research Group TEP-968 “Tecnologías para la Economía Circular” (Technologies for Circular Economy) of Granada University for their contribution to this research.The environmental problems associated with the construction sector have promoted the worldwide scientific community to pay attention to the use of recycled aggregates from construction and demolition waste. SciMAT and VOSviewer bibliometric tools have been applied in order to analyse, quantify and visualise the conceptual and social aspects of this scientific field, as well as its evolution between 1973 and 2019. The study of 843 scientific papers in this field has shown that the most important thematic area has been Recycling. In general, the common objective of the published papers was to study the efficient use of resources contained in construction and demolition waste due to their treatment to produce recycled aggregates, particularly for use in concrete. Likewise, some lacks have been observed in other areas of the analysed field, e.g. the use recycled aggregates in applications subject to less demanding regulations (mortars, precast concrete products, or green roofs).Los problemas medioambientales asociados al sector de la construcción han promovido que la comunidad científica mundial preste una mayor atención al uso de áridos reciclados procedentes de residuos de construcción y demolición. Para analizar, cuantificar y visualizar los aspectos más relevantes de este campo científico, así como su evolución entre 1973 y 2019, se han aplicado las herramientas bibliométricas SciMAT y VOSviewer. La revisión bibliométrica de 843 trabajos científicos publicados en este campo ha mostrado que el área temática más importante ha sido el Reciclaje. El objetivo común de los mismos ha sido el estudio del uso eficiente de los recursos contenidos en los residuos de construcción y demolición para producir áridos reciclados y ser usados en hormigón. Asimismo, se han observado algunas carencias en otros ámbitos del campo analizado, como el uso de áridos reciclados en aplicaciones sujetas a normativas menos exigentes (morteros, prefabricados no estructurales o cubiertas verdes).Spanish Ministry for Science Innovation and UniversitiesDepartments of Building Construction and Civil EngineeringResearch Group TEP-968 “Tecnologías para la Economía Circular” (Technologies for Circular Economy) of Granada Universit

    Metric dimension of maximal outerplanar graphs

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    In this paper, we study the metric dimension problem in maximal outerplanar graphs. Concretely, if ß(G) denotes the metric dimension of a maximal outerplanar graph G of order n, we prove that 2=ß(G)=¿2n5¿ and that the bounds are tight. We also provide linear algorithms to decide whether the metric dimension of G is 2 and to build a resolving set S of size ¿2n5¿ for G. Moreover, we characterize all maximal outerplanar graphs with metric dimension 2.Peer ReviewedPostprint (author's final draft

    Factors influencing the presence of sand flies in Majorca (Balearic Islands, Spain) with special reference to Phlebotomus pernicious, vector of Leishmania infantum

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    Background: Although the Mediterranean island of Majorca is an endemic area of leishmaniosis, there is a lack of up-to-date data on its sand fly fauna, the last report dating from 1989. The aim of the present study was to provide information on the current sand fly distribution, the potential environmental factors favoring the presence of Phlebotomus perniciosus and which areas are at risk of leishmaniosis. Methods: In July 2008 sand fly captures were carried out in Majorca with sticky castor oil interception traps. The capture stations were distributed in 77 grids (5x5 km2) covering the entire island. A total of 1,882 sticky traps were set among 111 stations. The characteristics of the stations were recorded and maps were designed using ArcGIS 9.2 software. The statistical analysis was carried out using a bivariate and multivariate logistic regression model. Results: The sand fly fauna of Majorca is composed of 4 species: Phlebotomus perniciosus, P sergenti, P. papatasi and Sergentomyia minuta. P. perniciosus, responsible for Leishmania infantum transmission, was captured throughout the island (frequency 69.4 %), from 6 to 772 m above sea level. Through logistic regression we estimated the probability of P. perniciosus presence at each sampling site as a function of environmental and meteorological factors. Although in the initial univariate analyses the probability of P. perniciosus presence appeared to be associated with a wide variety of factors, in the multivariate logistic regression model only altitude, settlement, aspect, drainage hole construction, adjacent flora and the proximity of a sheep farm were retained as positive predictors of the distribution of this species. Conclusions: P. perniciosus was present throughout the island, and thereby the risk of leishmaniosis transmission. The probability of finding P. perniciosus was higher at altitudes ranging from 51 to 150 m.a.s.l., with adjacent garrigue shrub vegetation, at the edge of or between settlements, and in proximity to a sheep farm

    Nutraceutical Extract from Dulse (Palmaria palmata L.) Inhibits Primary Human Neutrophil Activation

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    Palmaria palmata L. (Palmariaceae), commonly known as "dulse", is a red alga that grows on the northern coasts of the Atlantic and Pacific oceans, and is widely used as source of fiber and protein. Dulse is reported to contain anti-inflammatory and antioxidant compounds, albeit no study has investigated these effects in primary human neutrophils. Implication strategies to diminish neutrophil activation have the potential to prevent pathological states. We evaluated the ability of a phenolic dulse extract (DULEXT) to modulate the lipopolysaccharide (LPS)-mediated activation of primary human neutrophils. Intracellular reactive oxygen species (ROS) were measured by fluorescence analysis and nitric oxide (NO) production using the Griess reaction. Inflammatory enzymes and cytokines were detected by ELISA and RT-qPCR. The results show that DULEXT diminished the neutrophil activation related to the down-regulation of TLR4 mRNA expression, deceased gene expression and the LPS-induced release of the chemoattractant mediator IL-8 and the pro-inflammatory cytokines IL-1β, IL-6 and TNF-α. ROS, NO, and myeloperoxidase (MPO) were also depressed. The data indicated that DULEXT has the potential to disrupt the activation of human primary neutrophils and the derived inflammatory and prooxidant conditions, and suggest a new role for Palmaria palmata L. in the regulation of the pathogenesis of health disorders in which neutrophils play a key role, including atherosclerosisSpanish Ministry of Science, Innovation and Universities grant CYTED-2019 119RT056

    Identifying High-risk Individuals For Lung Cancer Screening: Going Beyond Nlst Criteria

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    Background There are two main types of strategies to identify target population for lung cancer screening: 1) strategies based on age and cumulative smoking criteria, 2) risk prediction models allowing the calculation of an individual risk. The objective of this study was to compare different strategies to identify the proportion of the Spanish population at high risk of developing lung cancer, susceptible to be included in a lung cancer screening programme. Methods Cross-sectional study. We used the data of the Spanish National Interview Health Survey (ENSE) of 2011-2012 (21,006 individuals) to estimate the proportion of participants at high risk of developing lung cancer. This estimation was performed using the U.S. national lung screening trial (NLST) criteria and a 6-year prediction model (PLCOm2012), both independently and in combination. Results The prevalence of individuals at high risk of developing lung cancer according to the NLST criteria was 4.9% (7.9% for men, 2.4% for women). Among the 1,034 subjects who met the NLST criteria, 533 (427 men and 106 women) had a 6-year lung cancer risk >= 2.0%. The combination of these two selection strategies showed that 2.5% of the Spanish population had a high risk of developing lung cancer. However, this selection process did not take into account different groups of subjects = 2%, such as heavy smokers <55 years old who were long-time former smokers, and ever smokers having smoked <30 pack-years with other risk factors. Conclusions Further research is needed to determine which selection strategy achieves a higher benefit/harm ratio and to assess other prevention strategies for individuals with elevated risk for lung cancer but who do not meet the screening eligibility criteria

    Paired and semipaired domination in near-triangulations

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    A dominating set of a graph G is a subset D of vertices such that every vertex not in D is adjacent to at least one vertex in D. A dominating set D is paired if the subgraph induced by its vertices has a perfect matching, and semipaired if every vertex in D is paired with exactly one other vertex in D that is within distance 2 from it. The paired domination number, denoted by ¿pr(G), is the minimum cardinality of a paired dominating set of G, and the semipaired domination number, denoted by ¿pr2(G), is the minimum cardinality of a semipaired dominating set of G. A near-triangulation is a biconnected planar graph that admits a plane embedding such that all of its faces are triangles except possibly the outer face. We show in this paper that ¿pr(G) = 2b n 4 c for any neartriangulation G of order n = 4, and that with some exceptions, ¿pr2(G) = b 2n 5 c for any near-triangulation G of order n = 5.Peer ReviewedPreprin

    cmv1 is a gate for Cucumber mosaic virus transport from bundle sheath cells to phloem in melon

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    Cucumber mosaic virus (CMV) has the broadest host range among plant viruses, causing enormous losses in agriculture. In melon, strains of subgroup II are unable to establish a systemic infection in the near‐isogenic line SC12‐1‐99, which carries the recessive resistance gene cmv1 from the accession PI 161375, cultivar ‘Songwhan Charmi’. Strains of subgroup I overcome cmv1 resistance in a manner dependent on the movement protein. We characterized the resistance conferred by cmv1 and established that CMV‐LS (subgroup II) can move from cell to cell up to the veins in the inoculated leaf, but cannot enter the phloem. Immunogold labelling at transmission electron microscopy level showed that CMV‐LS remains restricted to the bundle sheath (BS) cells in the resistant line, and does not invade vascular parenchyma or intermediary cells, whereas, in the susceptible line ‘Piel de Sapo’ (PS), the virus invades all vein cell types. These observations indicate that the resistant allele of cmv1 restricts systemic infection in a virus strain‐ and cell type‐specific manner by acting as an important gatekeeper for virus progression from BS cells to phloem cells. Graft inoculation experiments showed that CMV‐LS cannot move from the infected PS stock into the resistant cmv1 scion, thus suggesting an additional role for cmv1 related to CMV transport within or exit from the phloem. The characterization of this new form of recessive resistance, based on a restriction of virus systemic movement, opens up the possibility to design alternative approaches for breeding strategies in melon.Fil: Guiu Aragonés, Cèlia. Consejo Superior de Investigaciones Científicas; España. Institut de Recerca i Tecnologia Agroalimentàries; España. Universitat Autònoma de Barcelona; EspañaFil: Sánchez Pina, María Amelia. Consejo Superior de Investigaciones Científicas; España. Centro de Edafología y Biología Aplicada del Segura; EspañaFil: Díaz Pendón, Juan Antonio. Consejo Superior de Investigaciones Científicas; España. Universidad de Málaga; EspañaFil: Peña, Eduardo José. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Biotecnología y Biología Molecular. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Biotecnología y Biología Molecular; Argentina. Centre National de la Recherche Scientifique. Institut de Biologie Moléculaire des Plantes; FranciaFil: Heinlein, Manfred. Centre National de la Recherche Scientifique. Institut de Biologie Moléculaire des Plantes; FranciaFil: Martín Hernández, Ana Montserrat. Consejo Superior de Investigaciones Científicas; España. Institut de Recerca i Tecnologia Agroalimentàries; España. Universitat Autònoma de Barcelona; Españ
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