Multimetric Supergravities

Making use of integral forms and superfield techniques we propose supersymmetric extensions of the multimetric gravity Lagrangians in dimensions one, two, three and four. The supersymmetric interaction potential covariantly deforms the bosonic one, producing in particular suitable super-symmetric polynomials generated by the Berezinian. As an additional application of our formalism we construct supersymmetric multi-Maxwell theories in dimensions three and four.Comment: 37 pages, Latex2e, no figure

Analysis of the Spectral Energy Distributions of Fermi bright blazars

Blazars are a small fraction of all extragalactic sources but, unlike other objects, they are strong emitters across the entire electromagnetic spectrum. In this study we have conducted a detailed investigation of the broad-band spectral properties of the gamma-ray selected blazars of the Fermi-LAT Bright AGN Sample (LBAS). By combining the accurately estimated Fermi gamma-ray spectra with Swift, radio, NIR-Optical and hard-X/gamma-ray data, collected within three months of the LBAS data taking period, we were able to assemble high-quality and quasi-simultaneous Spectral Energy Distributions (SED) for 48 LBAS blazars.Comment: 6 pages, 8 figures, "2009 Fermi Symposium", "eConf Proceedings C091122

Design, synthesis and biological activity of selective hCAs inhibitors based on 2-(benzylsulfinyl)benzoic acid scaffold

A large library of derivatives based on the scaffold of 2-(benzylsulfinyl)benzoic acid were synthesised and tested as atypical inhibitors against four different isoforms of human carbonic anhydrase (hCA I, II, IX and XII, EC 4.2.1.1). The exploration of the chemical space around the main functional groups led to the discovery of selective hCA IX inhibitors in the micromolar/nanomolar range, thus establishing robust structure-activity relationships within this versatile scaffold. HPLC separation of some selected chiral compounds and biological evaluation of the corresponding enantiomers was performed along with molecular modelling studies on the most active derivatives

Generalised linear mixed model analysis via sequential Monte Carlo sampling

We present a sequential Monte Carlo sampler algorithm for the Bayesian analysis of generalised linear mixed models (GLMMs). These models support a variety of interesting regression-type analyses, but performing inference is often extremely difficult, even when using the Bayesian approach combined with Markov chainMonte Carlo (MCMC). The SequentialMonte Carlo sampler (SMC) is a new and generalmethod for producing samples from posterior distributions. In thisarticle we demonstrate use of the SMC method for performing inference for GLMMs. We demonstrate the effectiveness of the method on both simulated and real data, and find that sequential Monte Carlo is a competitive alternative to the available MCMC techniques. © 2008, Institute of Mathematical Statistics. All rights reserved

Quantificação do teor de antocianinas totais da polpa de açaí de diferentes populações de açaizeiro.

bitstream/item/28193/1/BPD60.pdfDisponível também on-line

Proton irradiation of a swept charge device at cryogenic temperature and the subsequent annealing

A number of studies have demonstrated that a room temperature proton irradiation may not be sufficient to provide an accurate estimation of the impact of the space radiation environment on detector performance. This is a result of the relationship between defect mobility and temperature, causing the performance to vary subject to the temperature history of the device from the point at which it was irradiated. Results measured using Charge Coupled Devices (CCD) irradiated at room temperature therefore tend to differ from those taken when the device was irradiated at a cryogenic temperature, more appropriate considering the operating conditions in space, impacting the prediction of in-flight performance. This paper describes the cryogenic irradiation, and subsequent annealing of an e2v technologies Swept Charge Device (SCD) CCD236 irradiated at −35.4°C with a 10 MeV equivalent proton fluence of 5.0 × 108 protons centerdot cm−2. The CCD236 is a large area (4.4 cm2) X-ray detector that will be flown on-board the Chandrayaan-2 and Hard X-ray Modulation Telescope spacecraft, in the Chandrayaan-2 Large Area Soft X-ray Spectrometer and the Soft X-ray Detector respectively. The SCD is readout continually in order to benefit from intrinsic dither mode clocking, leading to suppression of the surface component of the dark current and allowing the detector to be operated at warmer temperatures than a conventional CCD. The SCD is therefore an excellent choice to test and demonstrate the variation in the impact of irradiation at cryogenic temperatures in comparison to a more typical room temperature irradiation

Fertilidade de cabras leiteiras exploradas na região semi-árida do Nordeste do Brasil após inseminação artificial e utilização por até três vezes do dispositivo de liberação controlada de drogas (CIDR) para sincronização do estro.

O objetivo desse trabalho foi avaliar o efeito da utilização do dispositivo de liberação controlada de drogas (CIDR) por até três vezes sobre o desempenho reprodutivo de cabras leiteiras exploradas no semi-árido do Nordeste do Brasil. Foram utilizadas 45 cabras divididas em três tratamentos de sincronização do estro, sendo: CIDR1x (n = 15), tratadas com CIDR novo contendo 0,3 g de progesterona que permaneceu na porção cranial da vagina durante nove dias. Dois dias antes da retirada do dispositivo, foi aplicado 75 µg de d-cloprostenol e 300 UI de gonadotrofina coriônica eqüina (eCG). Para os demais tratamentos, foi utilizado o mesmo protocolo hormonal, diferindo apenas pelo uso do CIDR pela segunda vez no CIDR2x (n = 15) e uso pela terceira vez no CIDR3x (n = 15). Todos os animais manifestaram estro nos três tratamentos. O intervalo entre a retirada do dispositivo e o início do estro (13,3 ± 1,9 h vs. 13,8 ± 4,5 h vs. 13,3 ± 2,5 h), bem como, a duração do estro (33,6 ± 12,7 h vs. 29,6 ± 5,6 h vs. 32,8 ± 7,9 h) não diferiram (P>0,05) entre os tratamentos CIDR1x, CIDR2x e CIDR3x, respectivamente. Os tratamentos mostraram uma forte sincronia, pois 93,3 % (42/45) das fêmeas manifestaram estro em até 16 h após a retirada do CIDR. A fertilidade média após inseminação artificial foi superior a 82,0 %, não havendo diferença significativa (P>0,05) entre os tratamentos. A utilização do CIDR por até três vezes foi viável na sincronização do estro de caprinos leiteiros

IGRA test for TB in COVID-19: role of corticosteroids

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