The Effects of Stress on Distance Perception

Although there has been a great deal of research on binocular distance perception (Foley, 1980; Gogel, 1977), a number of questions remain unexplored. One such question involves how our ability to perceive distances is influenced by fitness and stress (internal and external). Previous research has shown that kinesthetic stress (via backpack weight) influences a person’s ability to accurately guess distances (Proffitt, Bhalla, Gossweiler, & Midgett, 2003). This research did not only attempt to replicate previous work, but also extend it by exploring potential interactions between fitness level and mental stress on distance perception, a combination that is often encountered by soldiers, firefighters, and rescue workers. Mental stress was measured using the State Anxiety Inventory test (Spielberger, Reheiser, & Sydeman, 1995) and cardiovascular fitness was measured using MET scores (Jurca et al., 2005). Physical stress was manipulated by asking participants to estimate distances and then walk blindly to the target while carrying a backpack weighing 20% of their weight. We were unable to replicate Proffitt. We did however find a positive correlation between cardiovascular fitness and error in the second block of the blind walking task for the heavy backpack condition, r(22) = -.45, p = 0.03

Transversal dances across time and space: Feminist strategies for a critical heritage studies

Transversal dances across time and space: Feminist strategies for a critical heritage studie

Winds in Star Clusters Drive Kolmogorov Turbulence

Intermediate and massive stars drive fast and powerful isotropic winds that interact with the winds of nearby stars in star clusters and the surrounding interstellar medium (ISM). Wind-ISM collisions generate astrospheres around these stars that contain hot $T\sim 10^7$ K gas that adiabatically expands. As individual bubbles expand and collide they become unstable, potentially driving turbulence in star clusters. In this paper we use hydrodynamic simulations to model a densely populated young star cluster within a homogeneous cloud to study stellar wind collisions with the surrounding ISM. We model a mass-segregated cluster of 20 B-type young main sequence stars with masses ranging from 3--17 $M_{\odot}$. We evolve the winds for $\sim$11 kyrs and show that wind-ISM collisions and over-lapping wind-blown bubbles around B-stars mixes the hot gas and ISM material generating Kolmogorov-like turbulence on small scales early in its evolution. We discuss how turbulence driven by stellar winds may impact the subsequent generation of star formation in the clusterComment: 12 pages, 5 figures, Accepted for publication in ApJ

Risk, Reliability and Resilience: Phytolith Evidence for Alternative 'Neolithization' Pathways at Kharaneh IV in the Azraq Basin, Jordan.

'Neolithization' pathway refers to the development of adaptations that characterized subsequent Neolithic life, sedentary occupations, and agriculture. In the Levant, the origins of these human behaviors are widely argued to have emerged during the Early Epipaleolithic (ca. 23 ka cal BP). Consequently, there has been a pre-occupation with identifying and modeling the dietary shift to cereal and grains during this period, which is considered to have been a key development that facilitated increasing sedentism and, eventually, agriculture. Yet, direct evidence of plant use in the form of macrobotanical remains is extremely limited at Epipaleolithic sites and the expected 'Neolithization' pathway has not been robustly demonstrated. However, new direct microbotanical phytolith evidence from the large aggregation site of Kharaneh IV, in the Azraq Basin, suggests that increasingly settled occupation was not the result of wild grass and cereal use, but rather the result of a typical hunter-gatherer balance, based on the use of mostly reliable resources supplemented by some risky resources. Moreover, and illustrating this balance, the direct botanical evidence emphases the importance of the wetlands as an under-recognized reliable plant resource. Significantly, the use of these reliable wetland plant resources at Kharaneh IV represents an unexpected 'Neolithization' pathway

The Lantern Vol. 66, No. 2, Spring 1999

• Dowry • The Ballad of the Lonely Thinker • Dissipation • Parliament Light • Reflecting Hood • Tonight • Decree • Not Yet • The Man in the Moon • The Sound and/or Fury • Uh Huh • Watch • The Futility of a Drizzle in a Worsening Draught • The Answering Machine • Felix Culpa • Kiss Off • Amorous • Summer of the Burning Pizzas • Life Without Shoelaces • Hermes and Aphrodite • Win! Twins! • From 69 Slices of Hell • Boardwalk Cowboyhttps://digitalcommons.ursinus.edu/lantern/1154/thumbnail.jp

Generalisability of vaccine effectiveness estimates: an analysis of cases included in a postlicensure evaluation of 13-valent pneumococcal conjugate vaccine in the USA

External validity, or generalisability, is the measure of how well results from a study pertain to individuals in the target population. We assessed generalisability, with respect to socioeconomic status, of estimates from a matched case–control study of 13-valent pneumococcal conjugate vaccine effectiveness for the prevention of invasive pneumococcal disease in children in the USA

Effects of obstructive sleep apnea and its treatment over the erectile function: a systematic review

Erectile dysfunction (ED) is considered a condition with a broad range of etiologies. Obstructive sleep apnea (OSA) syndrome is one of the lesser studied risk factors for ED. We intend to summarize the current evidence on the relationship between OSA and sexual impairment, focusing on the results in terms of erectile function of the different therapies offered to OSA patients. A systematic review was conducted, selecting articles related to the physiology of OSA and ED, and to the treatments of OSA syndrome and their reported outcomes in erectile and sexual function. Higher prevalences of ED in the OSA groups have been published. However, whether this effect on the erectile function occurs in the entire range of OSA severities remains unclear. Several hypotheses were proposed to explain the physiology of this association. Continuous Positive Airway Pressure as a treatment for OSA patients with ED has achieved a significative improvement in the sexual parameters in most of the studies. Phosphodiesterase type 5 inhibitors (iPDE5) on demand are useful as a treatment for ED in this subgroup of patients, with high satisfaction rates. The surgical treatment for the OSA evidenced benefits over the erectile function, and the effect on the sexual satisfaction of the therapy using Mandibular Advancement Devices is still undefined

Mass spectrometry imaging of hair identifies daily maraviroc adherence in HPTN 069/ACTG A5305

Objective measures of adherence for antiretrovirals used as pre-exposure prophylaxis (PrEP) are critical for improving preventative efficacy in both clinical trials and real-world application. Current objective adherence measures either reflect only recent behavior (eg days for plasma or urine) or cumulative behavior (eg months for dried blood spots). Here, we measured the accumulation of the antiretroviral drug maraviroc (MVC) in hair strands by infrared matrix-assisted laser desorption electrospray ionization (IR-MALDESI) mass spectrometry imaging (MSI) to evaluate adherence behavior longitudinally at high temporal resolution. An MSI threshold for classifying daily adherence was established using clinical samples from healthy volunteers following directly observed dosing of 1 to 7 doses MVC/week. We then used the benchmarked MSI assay to classify adherence to MVC-based PrEP regimens in hair samples collected throughout the 48-week HPTN069/ACTGA5305 study. We found that only ~32% of investigated hair samples collected during the study’s active dosing period showed consistent daily PrEP adherence throughout a retrospective period of 30 days, and also found that profiles of daily individual adherence from MSI hair analysis could identify when patients were and were not taking study drug. The assessment of adherence from MSI hair strand analysis was 62% lower than adherence classified using paired plasma samples, the latter of which may be influenced by white-coat adherence. These findings demonstrate the ability of MSI hair analysis to examine daily variability of adherence behavior over a longer-term measurement and offer the potential for longitudinal comparison with risk behavior to target patient-specific adherence interventions and improve outcomes