A Flexible Approach to the Multidimensional Model: The Fuzzy Datacube

As a result of the use of OLAP technology in new fields of knowledge and the merge of data from different sources, it has become necessary for models to support this technology. In this paper, we propose a new multidimensional model that can manage imprecision both in dimensions and facts. Consequently, the multidimensional structure is able to model data imprecision resulting from the integration of data from different sources or even information from experts, which it does by means of fuzzy logic

Association of trypanosoma cruzi infection with risk factors and electrocardiographic abnormalities in northeast Mexico

Background: American trypanosomiasis is a major disease and public health issue, caused by the protozoan parasite Trypanosoma cruzi. The prevalence of T. cruzi has not been fully documented, and there are few reports of this issue in Nuevo Leon. The aim of this study was to update the seroprevalence rate of T. cruzi infection, including an epidemiological analysis of the risk factors associated with this infection and an electrocardiographic (ECG) evaluation of those infected. Methods: Sera from 2,688 individuals from 10 municipalities in the state of Nuevo Leon, Mexico, were evaluated using an enzyme-linked immunosorbent assay and an indirect hemagglutination assay. An ECG case–control study was performed in subjects seropositive for T. cruzi and the results were matched by sex and age to seronegative residents of the same localities. A univariate analysis with χ 2 and Fisher’s exact tests was used to determine the association between seropositivity and age (years), sex, and ECG changes. A multivariate analysis was then performed to calculate the odd ratios between T. cruzi seropositivity and the risk factors. Results: The seropositive rate was 1.93% (52/2,688). In the ECG study, 22.85% (8/35) of the infected individuals exhibited ECG abnormalities. Triatoma gerstaeckeri was the only vector reported. The main risk factors were ceiling construction material (P ≤ 0.0024), domestic animals (P ≤ 0.0001), and living in rural municipalities (P ≤ 0.0025). Conclusions: These findings demonstrate a 10-fold higher prevalence of Chagas disease than previously reported (0.2%), which implies a serious public health threat in northeastern Mexico. The epidemiological profile established in this study differs from that found in the rest of Mexico, where human populations live in close proximity to domiciliary triatomine

Caso clínico: Vía aérea difícil en paciente con Espondilitis Anquilopoyética severa (II)

Segunda parte del caso descrito en el artículo anterior: Caso clínico: Vía aérea difícil en paciente con Espondilitis Anquilopoyética severa (I

Validity and Reproducibility of a Food Frequency Questionnaire to Assess Nutrients Intake of Pregnant Women in the South-East of Spain

Proper nutrition during pregnancy is pivotal to maintain good health for the child and the mother. This study evaluates the reproducibility and validity of a food frequency questionnaire (FFQ) designed to assess nutrient intake during pregnancy in the GENEIDA (Genetics, Early life Environmental Exposures and Infant Development in Andalusia) prospective birth cohort study. In addition, the nutrient intake was estimated and then compared with European guidelines and other studies. Diet information was collected from 690 pregnant women using a FFQ administered at two periods of pregnancy (used for the reproducibility study) and 24-h dietary recall (for the validity study). Statistical approaches included Spearman’s correlation coefficient and percentage agreement, classifying women into the same or adjacent quintiles to assess reproducibility, and limits of agreement (LoA) to evaluate validity. In the study of reproducibility, significant correlations for nutrients adjusted for total energy had an average of 0.417. Moreover, the percentage of subjects classified in the same quintile for nutrient intakes were above 66%. In the validation study, the significant correlation for nutrients adjusted for total energy had an average of 0.272. Nevertheless, the percentage of results in the LoA was above 94%. Our results were similar to other studies suggesting that the FFQ used is a valid tool of collect dietary intakes for South-East Spanish pregnant women.Institute of Health Carlos III (PI13/01559), including The European Regional Development Fund (FEDER)Regional Health Council of Andalusia (Spain) (PI045-2014)Plan propio de Investigación y Transferencia of the University of Granada under the program “Intensificación de la Investigación, modalidad B”

Ley de asuetos, vacaciones y licencias de empleados públicos de el salvador y su impacto en el ambiente institucional del Centro Escolar Católico María Consoladora del Carpinello, Centro Escolar Dr. Humberto Quintero, y Complejo Educativo Capitán General Gerardo Barrios del Municipio de Santa Ana, Departamento de Santa Ana

En el marco de la Constitución de la República, como ley primaria que regula toda actividad en los diferentes sectores de la sociedad, ordena jurídicamente el comportamiento humano, derivando de ella las leyes secundarias y especiales, como la Ley de Asuetos, Vacaciones y Licencias de Empleados Públicos de El Salvador que debe conciliar intereses entre la administración y los empleados, garantizando que gocen de los beneficios establecidos en ell

Two highly divergent alcohol dehydrogenases of melon exhibit fruit ripening-specific expression and distinct biochemical characteristics

Alcohol dehydrogenases (ADH) participate in the biosynthetic pathway of aroma volatiles in fruit by interconverting aldehydes to alcohols and providing substrates for the formation of esters. Two highly divergent ADH genes (15% identity at the amino acid level) of Cantaloupe Charentais melon (Cucumis melo var. Cantalupensis) have been isolated. Cm-ADH1 belongs to the medium-chain zinc-binding type of ADHs and is highly similar to all ADH genes expressed in fruit isolated so far. Cm-ADH2 belongs to the short-chain type of ADHs. The two encoded proteins are enzymatically active upon expression in yeast. Cm-ADH1 has strong preference for NAPDH as a co-factor, whereas Cm-ADH2 preferentially uses NADH. Both Cm-ADH proteins are much more active as reductases with Kms 10–20 times lower for the conversion of aldehydes to alcohols than for the dehydrogenation of alcohols to aldehydes. They both show strong preference for aliphatic aldehydes but Cm-ADH1 is capable of reducing branched aldehydes such as 3-methylbutyraldehyde, whereas Cm-ADH2 cannot. Both Cm-ADH genes are expressed specifically in fruit and up-regulated during ripening. Gene expression as well as total ADH activity are strongly inhibited in antisense ACC oxidase melons and in melon fruit treated with the ethylene antagonist 1-methylcyclopropene (1-MCP), indicating a positive regulation by ethylene. These data suggest that each of the Cm-ADH protein plays a specific role in the regulation of aroma biosynthesis in melon fruit

Análisis de Tratamientos Pregerminativos Químicos en Semillas de Juglans Neotropica Diels De Procedencia de San Blas, Cantón Urcuquí, Imbabura-Ecuador

The seeds of Juglans neotropica Diels, having a very resistant testa to adverse conditions, interfere with germination at the nursery level, so there is a low production of plants in this species, which is important in different aspects: social, cultural, medicinal, among others. For this reason, it is necessary to determine the effect of pre-germination treatments of chemical origin and enrichment of substrates on the germination of J. neotropica Diels seeds from the San Blas parish, Urcuquí canton, Imbabura province. The research was carried out at the Yuyucocha Campus of the Técnica del Norte University, where both the seed quality and germination tests were carried out based on the provisions of the ISTA standards. The treatments used were chemical scarification with soaking in sodium hydroxide solutions, as well as enrichment of the substrate with cytokinins. The J. neotropica seed presented a 10% moisture content, while the percentage of purity was 97.66%; with an average weight per seed of 16.6 g; that in a kilogram it will carry 60 seeds. Regarding the effect of the interaction of pre-germination treatments of chemical origin and substrate enrichment on the germination of J. neotropica, it was evidenced that the best treatment was the one that had chemical scarification for 32 hours in a solution of hydroxide. 4% sodium, with the application of substrate enrichment with cytokinins.Las semillas de Juglans neotropica Diels al poseer una testa muy resistente a las condiciones adversas, producen una interferencia en la germinación a nivel de vivero, por lo que existe una baja producción de plantas en dicha especie, la cual posee una importancia en los aspectos sociales, culturales, medicinales, entre otros. Por tal motivo, es necesario determinar el efecto de tratamientos pregerminativos de origen químico y enriquecimiento de sustratos en la germinación de semillas de J. neotropica Diels provenientes de la parroquia San Blas, cantón Urcuquí, provincia de Imbabura. En la investigación se realizó en el Campus Yuyucocha de la Universidad Técnica del Norte, donde se realizó tanto las pruebas de calidad de las semillas y de germinación con base a lo establecido por las normas ISTA. Los tratamientos empleados fueron la escarificación química con remojo en soluciones de hidróxido de sodio, así como también el enriquecimiento del sustrato con citoquininas. La semilla de J. neotropica presentaron un 10% de contenido de humedad, mientras que el porcentaje de pureza fue de 97.66%; con un peso promedio por semilla de 16.6 g; es decir que en un kilogramo llevará 60 semillas. En cuanto al el efecto de la interacción de tratamientos pre – germinativos de origen químico y enriquecimiento de sustrato sobre la germinación de J. neotropica se evidenció que el mejor tratamiento fue el que contó con la escarificación química por 32 horas en una solución de hidróxido de sodio al 4%, con la aplicación del enriquecimiento de sustrato con citoquininas

A genetic modifier screen identifies chromosomal intervals harboring potential midline interacting genes

This work investigates the growth of B-C-N layers by chemical vapor deposition using methylamine borane (MeAB) as single-source precursor. MeAB has been synthesized and characterized, paying particular attention to the analysis of its thermolysis products, which are the gaseous precursors for B-C-N growth. Samples have been grown on Cu foils and transferred onto different substrates for their morphological, structural, chemical, electronic and optical characterizations. The results of these characterizations indicate a segregation of h-BN and Graphene-like (Gr) domains. However, there is an important presence of B and N interactions with C at the Gr borders, and of C interacting at the h-BN-edges, respectively, in the obtained nano-layers. In particular, there is significant presence of C-N bonds, at Gr/h-BN borders and in the form of N doping of Gr domains. The overall B:C:N contents in the layers is close to 1:3:1.5. A careful analysis of the optical bandgap determination of the obtained B-C-N layers is presented, discussed and compared with previous seminal works with samples of similar composition.Comment: 35 pages, 7 figure

Chemical vapor deposition growth of boron-carbon-nitrogen layers from methylamine borane thermolysis products

This is the Accepted Manuscript version of an article accepted for publication in Nanotechnology. IOP Publishing Ltd is not responsible for any errors or omissions in this version of the manuscript or any version derived from it. The Version of Record is available online at https://doi.org/10.1088/1361-6528/aa9c07This work investigates the growth of B-C-N layers by chemical vapor deposition using methylamine borane (MeAB) as the single-source precursor. MeAB has been synthesized and characterized, paying particular attention to the analysis of its thermolysis products, which are the gaseous precursors for B-C-N growth. Samples have been grown on Cu foils and transferred onto different substrates for their morphological, structural, chemical, electronic and optical characterizations. The results of these characterizations indicate a segregation of h-BN and graphene-like (Gr) domains. However, there is an important presence of B and N interactions with C at the Gr borders, and of C interacting at the h-BN-edges, respectively, in the obtained nano-layers. In particular, there is a significant presence of C-N bonds, at Gr/h-BN borders and in the form of N doping of Gr domains. The overall B:C:N contents in the layers is close to 1:3:1.5. A careful analysis of the optical bandgap determination of the obtained B-C-N layers is presented, discussed and compared with previous seminal works with samples of similar compositio