Safety and Immunogenicity of SARS-CoV-2 vaccines in people with HIV

Concise communication[Abstract] Objective: To evaluate the safety and the serological response after two doses of mRNA-based SARS-CoV-2 vaccination in people with HIV (PWH). Methods: Participants were evaluated 4 weeks after the second dose of mRNA-1273 or BNT162b2 vaccine. Tolerability was evaluated with a specific adverse event questionnaire. Patient's sera were analysed using LIAISON SARS-CoV-2 TrimericS IgG (DiaSorin). Results: One-hundred PWH were included, 75% of them men, with a mean age of 44 ± 11 years old, all receiving antiretroviral treatment and mostly with controlled viral loads (98% with HIV RNA 200 CD4+/μl. All patients seroconverted after vaccination (antibody concentration ≥33.8 binding antibody units [BAU]/ml). Only 3% of the patients had a low antibody concentration (2080 BAU/ml). Fifty-six patients had local or systemic symptoms, with mild arthromyalgia being the most common systemic symptom. No severe adverse events were reported. Conclusions: Vaccination with two doses of mRNA-1273 or BNT162b2 is well tolerated in PWH under effective antiretroviral treatment and it leads to a successful antibody response

Seroprevalence of HCV and HIV infections by year of birth in Spain: impact of US CDC and USPSTF recommendations for HCV and HIV testing

Instituto de Salud Carlos III; CP08/00214Instituto de Salud Carlos III; PI10/02166Instituto de Salud Carlos III; PI13/02266Instituto de Salud Carlos III; CM13/0032

práticas artísticas no ensino básico e secundário

A Educação Artística joga-se em muito mais locais que no ensino formal. As oportunidades formativas têm sido aproveitadas por museus, bibliotecas, centros culturais, exposições, festivais, associações e plataformas culturais, eventos, plataformas de disseminação artística, edições. Os artistas individuais têm vindo a integrar as dinâmicas relacionais e de criação de públicos nas suas obras, ao convocarem as audiências e implicarem o espectador. O terreno é limitado apenas pela imaginação, e as oportunidades de convocação alargam-se aos novos conteúdos e plataformas digitais, a par com a valorização do que é local e identitário: a revolução pode fazer-se pela cidadania.info:eu-repo/semantics/publishedVersio

Joinpoint regression analysis: trends in HCV and HIV seroprevalence according to year of birth.

<p>APC = <i>Annual percent change</i>.</p><p>Joinpoint regression analysis: trends in HCV and HIV seroprevalence according to year of birth.</p