94 research outputs found
MENCA experiment aboard India’s Mars Orbiter Mission
The Mars Exospheric Neutral Composition Analyser (MENCA) aboard the Indian Mars Orbiter Mission (MOM) is a quadrupole mass spectrometer-based experiment. Making use of the highly elliptical and low inclination (~150°) orbit of MOM, MENCA will conduct in situ measurements of the composition and radial distribution of the Martian neutral exosphere in the 1–300 amu mass range in the equatorial and low latitudes of Mars. The functionality of MENCA has been tested during the Earth-bound and heliocentric phases of MOM before its operation in the Martian orbit. This article describes the scientific objectives, instrument details, design and development, test and evaluation, and calibration of the MENCA instrument
Oxacycle fused [1]benzothieno[3,2-b][1]benzothiophene derivatives: synthesis, electronic structure, electrochemical properties, ionisation potential, and crystal structure
The molecular properties of [1]benzothieno[3,2-b][1]benzothiophene (BTBT) are vulnerable to the structural modifications which in turn are decided by the functionalization of the backbone. Hence versatile synthetic strategies are needed to discover the properties of this molecule. To address this, we have attempted heteroatom (oxygen) functionalization of BTBT by a concise and easily scalable synthesis. Four-fold hydroxy substituted BTBT is the key intermediate, from which the compounds 2,3,7,8- bis(ethylenedioxy)-[1]benzothieno[3,2-b][1]benzothiophene and 2,3,7,8- bis(methylenedioxy)-[1]benzothieno[3,2-b][1]benzothiophene are synthesized. The difference in ether functionalities on the BTBT scaffold influences the ionisation potential values substantially. The crystal structure reveals the transformation of the herringbone motif in bare BTBT towards π stacked columns in the newly synthesized derivatives. The results are further elaborated with the aid of quantum chemical calculations
A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)
Meeting abstrac
Recovery of dialysis patients with COVID-19 : health outcomes 3 months after diagnosis in ERACODA
Background. Coronavirus disease 2019 (COVID-19)-related short-term mortality is high in dialysis patients, but longer-term outcomes are largely unknown. We therefore assessed patient recovery in a large cohort of dialysis patients 3 months after their COVID-19 diagnosis. Methods. We analyzed data on dialysis patients diagnosed with COVID-19 from 1 February 2020 to 31 March 2021 from the European Renal Association COVID-19 Database (ERACODA). The outcomes studied were patient survival, residence and functional and mental health status (estimated by their treating physician) 3 months after COVID-19 diagnosis. Complete follow-up data were available for 854 surviving patients. Patient characteristics associated with recovery were analyzed using logistic regression. Results. In 2449 hemodialysis patients (mean ± SD age 67.5 ± 14.4 years, 62% male), survival probabilities at 3 months after COVID-19 diagnosis were 90% for nonhospitalized patients (n = 1087), 73% for patients admitted to the hospital but not to an intensive care unit (ICU) (n = 1165) and 40% for those admitted to an ICU (n = 197). Patient survival hardly decreased between 28 days and 3 months after COVID-19 diagnosis. At 3 months, 87% functioned at their pre-existent functional and 94% at their pre-existent mental level. Only few of the surviving patients were still admitted to the hospital (0.8-6.3%) or a nursing home (∼5%). A higher age and frailty score at presentation and ICU admission were associated with worse functional outcome. Conclusions. Mortality between 28 days and 3 months after COVID-19 diagnosis was low and the majority of patients who survived COVID-19 recovered to their pre-existent functional and mental health level at 3 months after diagnosis
The prolactin receptor mediates HOXA1-stimulated oncogenicity in mammary carcinoma cells
10.3892/ijo.2012.1660International Journal of Oncology4162285-2295IJON
Studies on the growth, thermal and optical properties of 4-aminopyridinium p-aminobenzoate dihydrate single crystals
4-aminopyridinium p-aminobenzoate dihydrate (4APAB) compound was synthesized successfully and single crystals were grown by slow evaporation solution growth technique. Single crystal X-ray diffraction study was conducted to evaluate the cell parameters of grown crystal. The crystalline perfection of 4APAB crystal was assessed by HRXRD studies. Thermal studies revealed the thermal stability of grown crystal up to 126 degrees C. The optical transmittance window and lower cut-off wavelength of 4APAB crystal were estimated by using UV-vis-NIR studies. The second harmonic efficiency of 4APAB was measured by powder test using Nd:YAG laser radiation. The dielectric tensor studies revealed that 4APAB crystal shows normal dielectric behavior. The single and multiple shots laser damage threshold values of grown crystal were measured
HF backscatter radar at the magnetic equator : System details and preliminary results
77-90A phase
coherent, pulsed, monostatic and moderately high power HF Doppler radar,
operating at 18 and 9 MHz has been installed at the magnetic equatorial
station, Trivandrum (8.5°N, 77°E; dip 0.5°N), India. It is a powerful tool to
study the plasma instability processes responsible for the generation of
equatorial electrojet (EEJ) and equatorial spread-F (ESF) irregularities. A
novelty in the radar system is the usage of the same phased array antenna at
the two harmonically related frequencies of 18 and 9 MHz. The radar employs
Doppler beam swinging (DBS) technique with beam orientations of vertical and
±30° off zenith in the E-W plane, providing the unique capability of obtaining
both zonal and vertical drifts of the ionospheric irregularities. The radar is
also capable of providing zonal wind information in the region of 80-95 km. The
new radar has opened up the possibilities of investigating different aspects of
EEJ, like the E-W spectral asymmetry, diurnal pattern of the electric field and
the effect of small scale plasma turbulence on the large scale EEJ altitude
structure. In this paper the detailed system description, data processing
scheme and some preliminary results obtained using the radar at 18 MHz are
presented
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