133 research outputs found
Synthesis of Functionalised 3-Isochromanones by Silylcarbocyclisation/Desilylation Reactions
A new protocol for the synthesis of 3-isochromanone derivatives based on rhodium-promoted silylcarbocyclisation
reactions of ethynylbenzyl alcohol with different arylsilanes is described. The structure of the isochromanone depends upon the reaction conditions used: when the reaction is carried out without base, (Z)-4-(aryldimethylsilyl)methylene]isochroman-3-ones are obtained as major products. These compounds can be submitted to a desilylation/aryl migration reaction to give 4-(arylmethyl)isochroman-3-ones in high yields. In contrast, in the presence of DBU (1,8-diazabicyclo[5.4.0]undec-7-ene), hydrogenation of methyleneisochroman-3-ones takes place, and the corresponding -(silylmethyl)-3-isochromanones are formed. Moreover, when internal alkynes are treated with hydrosilanes under silylcarbocyclisation reaction conditions, alcoholysis of the hydrosilanes occurs exclusively
ChemInform Abstract: One-Pot Synthesis of 2-Aminotetrahydrothiopyrano[4,3-b]pyran-3-carbonitrile Derivatives Using Mesoporous NH 2
ChemInform Abstract: Graphite Oxide-Promoted One-Pot Synthesis and Oxidative Aromatization of Hantzsch 1,4-Dihydropyridines.
ChemInform Abstract: Efficient Method for the Reduction of Carbonyl Compounds by Triethylsilane Catalyzed by PdCl 2
ChemInform Abstract: Oxone/Iron(II) Sulfate/Graphite Oxide as a Highly Effective System for Oxidation of Alcohols under Ultrasonic Irradiation.
ChemInform Abstract: A Simple and Efficient Hydrogenation of Benzyl Alcohols to Methylene Compounds Using Triethylsilane and a Palladium Catalyst.
ChemInform Abstract: Palladium Catalyzed Mild Reduction of α,β-Unsaturated Compounds by Triethylsilane.
ChemInform Abstract: Cheap and Efficient Protocol for the Synthesis of Tetrahydroquinazolinone, Dihydropyrimidinone, and Pyrimidinone Derivatives.
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