199 research outputs found

    Intersection cohomology of Drinfeld's compactifications

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    Let XX be a smooth complete curve, GG be a reductive group and PGP\subset G a parabolic. Following Drinfeld, one defines a compactification \widetilde{\on{Bun}}_P of the moduli stack of PP-bundles on XX. The present paper is concerned with the explicit description of the Intersection Cohomology sheaf of \widetilde{\on{Bun}}_P. The description is given in terms of the combinatorics of the Langlands dual Lie algebra gˇ\check{\mathfrak g}.Comment: An erratum adde

    Airport airside balanced capacity usage and planning

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    U doktorskoj disertaciji je predložen postupak za analizu kapaciteta vazdušne strane aerodroma, za zadata fizička i operativna ograničenja, i zadate karakteristike potražnje. Ovaj postupak podrazumeva povezivanje (postojećeg) modela za procenu kapaciteta sistema poletno-sletnih staza sa (proširenim) modelom za procenu kapaciteta pristanišne platforme, kroz njihovu funkcionalnu vezu. Cilj ove doktorske disertacije je bio vrednovanje i, po potrebi, modifikovanje i proširenje postojećih modela za procenu kapaciteta platforme, kao i definisanje funkcionalne veze između poletno-sletne staze i platforme za različite tipove saobraćaja. Postojeći modeli su prošireni tako da uzimaju u obzir ograničenja po tipu aviona i korisnicima (npr. aviokompanije), kao i po vrsti saobraćaja. U cilju analize osetljivosti, predlažene su obvojnice za prikazivanje kapaciteta platforme određene konfiguracije, u zavisnosti od strukture potražnje u odnosu na glavne uticajne faktore. Analiza je obuhvatila dva osnovna tipa aerodroma sa aspekta njihove uloge u mrežama vazdušnog saobraćaja, a to su: izvorno-ciljni aerodromi, sa dominantnim saobraćajem od-tačke-do-tačke, i hub aerodromi, sa dominantnim transfernim saobraćajem za koji je karakteristično da se koncentriše u talase. Dodatno su analizirani i aerodromi na kojima postoje oba tipa saobraćaja. Rezultati disertacije pokazuju da se za izvorno-ciljne aerodrome može koristiti standardni pristup prilikom analize ukupnog kapaciteta vazdušne strane aerodroma, u kome se poletno-sletna staza i pristanišna platforma posmatraju odvojeno, pri čemu manji kapacitet nameće ograničenje ukupnog kapaciteta. Sa druge strane, u slučaju hub aerodroma kapacitet platforme i kapacitet poletno-sletne staze se ne mogu posmatrati nezavisno jedan od drugog. S tim u skladu, u ovoj doktorskoj disertaciji predložen je model za procenu kapaciteta platforme na hub aerodromima, koji pored konfiguracije platforme i strukture potražnje uzima u obzir i kapacitet poletno-sletne staze, kao i parametre koji opisuju talasnu strukturu saobraćaja...The thesis proposes an approach to analyzing the capacity of the existing (built) system under given physical and operational constraints and for given demand characteristics. The approach considers the linking of the (existing) runway capacity model with the (extended) apron capacity model, through the runway-apron functional relationship. The objective of the thesis was to evaluate and, if necessary, to modify/expand the existing apron capacity estimation models, as well as to define functional relationship between the runway system and apron(s). Existing apron capacity models are modified to include constraints on both aircraft classes and users (e.g. airlines), considering also different traffic types. The thesis also suggests apron capacity envelopes to illustrate sensitivity of apron capacity to changes in the demand structure with respect to dominant users, provided for a given apron configuration. Two general airport categories with respect to the role of the airport in the air transport network are analyzed: origin-destination airports (serving primarily point-to-point flights) and hub airports (serving primarily airline/alliance coordinated flights). Furthermore, the thesis also considers the co-existence of point-to-point and coordinated flights at a single airport. The results of the thesis show that the common approach in the overall airside capacity analysis can be applied at origin-destination airports: the runway system and apron(s) can be observed independently of each other, deriving the conclusion on the overall airside capacity by comparing the two. On the other hand, the finding of the thesis is that capacities of the runway system and apron(s) at the hub airports have to be observed linked to each other. Consequently, a model to estimate apron capacity at hub airport is offered in the thesis. In addition to apron configuration and demand structure it also takes into consideration: hubbing parameters and the runway system performance..

    Modules over the small quantum group and semi-infinite flag manifold

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    We develop a theory of perverse sheaves on the semi-infinite flag manifold G((t))/N((t))T[[t]]G((t))/N((t))\cdot T[[t]], and show that the subcategory of Iwahori-monodromy perverse sheaves is equivalent to the regular block of the category of representations of the small quantum group at an even root of unity

    Synthesis of new aliphatic diimino-dioximes and diamino-dioximes and their chelate complexes with transitional and radioactive metal: potential applications in medicine

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    U prvom delu ove teze izvršena je sinteza četiri jedinjenja iz klase diimino-dioksima, čijom redukcijom su dobijena četiri jedinjenja iz klase diamino-dioksima koja do sada nisu bila poznata u literaturi.Sinteza sva četiri diimino-dioksima je izvedena u protičnom rastvaraču (C2H5OH ili CH3OH), uz refluks ili na sobnoj temperaturi, u atmosferi azota i po potrebi u prisustvu katalitičke količine CH3COOH. Sinteza u aprotičnom rastvaraču (benzenu) izvedena je samo za dva diimino-dioksima. Redukcijom odgovarajućeg diimino-dioksima sa NaBH4 u C2H5OHanh, sintetisani su diamino-dioksimi.Jedinjenja su okarakterisana elementarnom analizom, elektronskom apsorpcionom i IR spektroskopijom, 1H i 13C NMR spektroskopijom.Sintetisani diamino-dioksimi grade komplekse sa radioaktivnim izotopom 99mTc. Navedena jedinjenja sadrže četiri atoma azota sa slobodnim parovima elektrona i ponašaju se kao donori elektrona pri građenju koordinativne veze sa 99mTc(V). Zbog navedenog svojstva, ispitivano je da li kompleksi sintetisanih diamino-dioksima sa 99mTc(V) mogu imati primenu u SPECT dijagnostičkoj nuklearnoj medicini. U okviru ove faze istraživanja izvršene su sledeće aktivnosti: obeležavanje diamino-dioksima sa 99mTc(V), određivanje prinosa obeleženih jedinjenja, određivanje stabilnosti nagrađenih kompleksa, određivanje lipofilnosti i proteinskog vezivanja obeleženih jedinjenja i praćenje biološke raspodele (biodistribucije) na eksperimentalnim životinjama.Jedinjenja iz klase diimino-dioksima, lako grade komplekse sa prelaznim metalima, samim tim i sa Cu(II). To je veoma značajno jer bi sintetisana jedinjenja diimino-dioksimske strukture zbog navedenog svojstva mogla biti lako obeležena i radioaktivnim izotopom 64Cu i imati potencijalnu primenu u PET dijagnostičkoj nuklearnoj medicini. Sintetisani su kompleksi jednog odabranog diimino-dioksima i dvovalentnih metala Cu(II),...In this thesis, the synthesis of four compounds from classes of diimine-dioximes have been given, and additionally after their reduction four compounds from classes of diamine-dioximes have been obtained, which have not been so far known in the literature.The synthesis of all four diimine-dioximes have been performed in a protic solvent (CH3OH or C2H5OH), at reflux or at room temperature, under nitrogen atmosphere, and optionally in the presence of a catalytic amount of CH3COOH. The synthesis in an aprotic solvent (benzene) has been performed for only two diimine-dioximes. After reduction of the corresponding diimine-dioximes with NaBH4 in C2H5OHanh, diamine-dioximes have been obtained.All obtained compounds have been characterized by elemental analysis, electronic absorption and IR spectroscopy, 1H and 13C NMR spectroscopy.Synthesized diamino-dioximes form complexes with radioactive isotope 99mTc. They contain four nitrogen atoms with free electron pairs and therefore act as electron donors in coordinating links with 99mTc (V). Because of this property, it have been examined whether the synthesized complexes with diamino-dioximes and 99mTc (V) may be used in the SPECT diagnostic nuclear medicine. For this purposes the following activities have been carried out: the labelling diamino-dioximes with 99mTc (V), the determination of the yield of labeled compounds, the determination of the stability of formed complexes, the determination of lipophilicity and protein binding of labeled compounds and biological monitoring of distribution (biodistribution) in experimental animals.Compounds from the class of diimine-dioximes easily form complexes with transition metals, and therefore with Cu(II). This is very important because the synthesized compounds with diimines-dioxime structure could be easily labeled with radioactive isotope 64Cu and could potentially be used in PET diagnostic nuclear medicine. Complexes..

    Development of integrated management process for operational work and maintenance of additional machinery at the surface coal mine with supporting informational-communication technologies

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    Polazeći od potreba savremenog menadžmenta za unapređenjem poslovanja preduzeća u uslovima dinamičnih promena tržišta, naučni cilj disertacije definisan je kao razvoj integrisanog modela informacionog sistema (IS) i procesne strukture preduzeća za realizaciju usluge pomoćnih radova mašinama pomoćne (rudarske) mehanizacije u proiizvodnji uglja na površinskom kopu, s obzirom na sve veću zavisnost ovih usluga od informacionih i komunikacionih tehnologija. Istraživanjem koje je usmereno na vezu i interakciju između IS i procesne strukture sektora/pogona pomoćne mehanizacije (PM) preduzeća, dobijen je Integrisani model (IM) koji obuhvata definisanje kako osnova i okvira razvoja IM, tako i IM pristupa integraciji poslovnog procesa i podrške informacionog sistema. Objektna analiza identifikovanih glavnih procesa PM preduzeća i funkcionalnih veza poslovnih procesa i informacionih sistema, rezultirala je definisanjem opšteg konceptualnog modela IS PM preduzeća i logičke arhitekture IS. Na osnovu Procesnog modela, IS modela i zahteva sistema upravljanja kvalitetom (Quality Management System-QMS) definisan je sopstveni pristup integraciji poslovnog procesa i informacionog sistema (IM pristup), logički IM model, sa definisanim elementima: poslovni proces PPi, informacioni sistem ISi, poslovni cilj PCi (kao ulaz u proces i kao izlaz iz procesa - realizovan poslovni cilj), kao i povratna sprega kojom se vrši unapređenje poslovnog procesa i istovremeno usklađivanje IS sa promenom. Proširenjem IM modela za PM preduzeća uvodi se Integrisani model preduzeća (IMP). Uvođenjem IM u poslovno okruženje u praksi definisane su faze Planiranja, Projektovanja i Implementacije kroz koje se PP i IS istovremeno i sinhronizovano razvijaju i uvode. Sprovedena eksperimentalna istraživanja u PM preduzeća poslužili su proveri IM. Prikazani su izabrani IM za Usluge pomoćni radovi i Tehničko održavanje mašina pomoćne mehanizacije - ključni za upravljanje PM preduzeća. Usluge se ne mogu skladištiti i zato je za PM preduzeća jedan od kritičnih faktora uspeha visok stepen raspoloživosti i gotovosti parka mašina. Primena implementiranog IM u operativnom radu u PM preduzeća potvrdila je njegovu upravljačku vrednost, kao alatka koja menadžmentu uspešno obezbeđuje podatke i informacije o indikatorima ključnih performansi poslovnih procesa za donošenje poslovnih odluka u realnom vremenu.Based on the needs of modern management to improve business operations in terms of dynamic market changes, the scientific goal of the dissertation is defined as the development of an integrated information system (IS) model and enterprise process structure for the implementation of services of additional operations by machinery of auxiliary (mining) machinery in coal production of surface mines, given the increasing dependence of these services on information and communication technologies. By the study, which is focused on the relationship and interaction between IS and process structure of the company’s sector/plant of auxiliary machinery (AM), an integrated model (IM) was obtained, which includes the definition as a basis and framework of the IM development and IM approach to the integration of business processes and information systems. The object analysis of identified main company’s AM and functional relationships of business processes and information systems has resulted in defining a general conceptual model of IS of company’s AM and logical IS architecture. Based on the process model, the IS model, and requirements of a quality management system (QMS), an own approach to the integration of business processes and information systems (IM access), the logic IM model, with defined elements is defined: PPi business process, ISi information system, PCi business objective (as input into the process and output from the process - realized business objective), as well as the feedback which is an improvement of the business processes and simultaneous IS alignment with the change. By expanding the IM model for company’s AM, the integrated enterprise model (IEM) is being introduced. By introducing IM into the business environment in practice, the Planning, Design and Implementation phases are defined, through which the PP and IS are simultaneously and synchronized developed and introduced. The conducted experimental researches within the AM of the company served as an IM check. Selected IM for Services of additional operations and Technical maintenance of machinery of auxiliary are presented – essential for the management of company’s AM. The services cannot be stored and therefore the high availability and readiness of the machine park is one of the critical success factors for the company’s AM. The application of the implemented IM within the operational work of the company’s AM has confirmed its managing value, as a tool which successfully provides data and information to the management on key performance indicators of business processes for real time business decision making

    Projektovanje selektivnih IIR digitalnih filtara sa linearnom fazom upotrebom analognih prototipova

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    Lack of universal approach for transforming analog filter prototypes into digital domain opens a possibility for further research in the field thus enabling both, improving existing and deriving novel methods. In the dissertation, a novel method in a form of transformation function for mapping complex angular frequency s into z domain will be covered. Digital counterparts of analog filters based on a special class of filters exhibiting critical monotonic pass-band amplitude characteristic will be presented for the first time. Complete procedure for designing IIR filters based on this class of filters will be implemented as a software solution. Phase-Invariance Method will be exploited for designing linear phase IIR filters. Hardware realization of the filters will be considered. The practical part of the thesis is devoted to IIR filter design in a form of (very large-scale integration) integrated circuit exploiting standard cells. Representative examples of IIR filter designs are realized up to the fabrication masks level (layout). Power consumption estimations based on layout parasitic elements are given as well

    Utjecaj parodontološke terapije na C-reaktivni protein i parodontne patogene kod pacijenata s parodontopatijom

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    Objective: Recent epidemiological studies have shown that individuals with periodontitis have significantly increased risk of developing coronary heart disease. Although the mechanism responsible for the relationship between periodontal disease and cardiovascular events is not fully understood, it is hypothesized that the removal of infection and inflammatory burden of periodontitis by therapy would be accompanied by a decrease in levels of the inflammatory marker C-reactive protein and a decreased risk of coronary heart disease. The aim of the present study was to determine whether the presence of chronic periodontitis and periodontal pathogens and subsequent periodontal treatment could influence the serum levels of C-reactive protein in a Serbian cohort. Material and Methods: Fifty adults with moderate to severe periodontitis who underwent complete mouth disinfection were evaluated to determine if periodontal therapy would result in decreased periodontal infammation and lower serum levels of an inflammatory marker. Subjects underwent measuring of periodontal disease severity and serum C-reactive protein, and periodontal pathogens (Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans) at the time of the baseline visit and again 6 and 12 months after treatment. Serum levels CRP were also obtained from 25 subjects without periodontitis in a control group. Results: The levels of CRP in the serum seemed not to be lower than those reported in other population in Western European countries. There were significant changes in clinical periodontal values, CRP levels and presence of periodontal pathogens when baseline values were compared to those taken after periodontal treatment completion. Conclusion: The obtained results confirm the hypothesis that periodontal therapy may contribute to elimination of periodontal inflammation and periodontal pathogens, and reduce serum level of CRP. Periodontitis may contribute to the systemic inflammatory burden of affected individuals since it was shown that periodontal therapy may decrease presence of periodontal pathogens and inflammatory markers

    Evalaution of radioiodination of synthesised meta-iodobenzylguanidine catalyzed by in situ generated Cu(i)

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    Meta-iodobenzylguanidine (m-IBG) is a biogenic amine precursor, noradrenaline analogue, which is actively taken up by tumors. In tracer amounts, [123/131I]-m-IBG is used as a radiopharmaceutical to target normal and malignant tissues of neuroadrenergic origin for diagnostic scintigraphy, and labeled with higher activities of 131I, it is used for therapy of phenochromocytoma and neuroblastoma. The increased clinical therapeutic use of unlabeled m-IBG at doses of up to 40 mg/m2 emphasizes the need for syntheses and an established quality protocol for this substance that relies on verifiable analytical parameters. Evaluation of radioiodination was necessary to obtain higher labeling yield (we achieved over 90% instead no more than 70%), because isotopic exchange labeling of m-IBG with 131I catalyzed by Cu(I) is much more efficient than with conveniently used ammonium sulphate.Physical chemistry 2006 : 8th international conference on fundamental and applied aspects of physical chemistry; Belgrade (Serbia); 26-29 September 200
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