Characterization of sex, age, and breed for a population of canine leishmaniosis diseased dogs.

Our study of a large canine population investigated whether the development of symptomatic canine leishmaniosis revealed any predilection for sex, age, or breed. Included in the study were 390 leishmaniosis-affected dogs that had been treated at the Hospital Clínic Veterinari attached to the Universitat Autònoma de Barcelona. Of the diseased dogs, 238 were male (61%) and 152 were females (39%), whereas percentages for males and females in the overall reference population of dogs treated at this unit were 53% and 47%, respectively, (P<0.05). Age distribution was bimodal, with the highest prevalence of the disease occurring at 2-4 years of age and a secondary peak occurring at seven years or over. The over represented breeds were the German shepherd (13.6% versus 6.35%, P<0.001), the Rottweiler (13.1% versus 3.0%, P<0.001), and the Boxer (7.9% versus 4.7%, P=0.002), whereas the underrepresented breeds were the Yorkshire terrier (0.5% versus 6.5%, P<0.001), and the Poodle (0.3% versus 3.0%, P<0.001)

Nation and Nationalism in the Contemporarity: Young Brazilians and Their Views over Brazil

El objetivo de este artículo es presentar los resultados de una investigación que problematizó la relación entre los jóvenes brasileños y los sentidos de pertenencia nacional, en sus múltiples mediaciones y lugares discursivos. A partir de la observación preliminar de que los jóvenes, en escenarios de escolarización, tendían a asumir una posición tácita de desvalorización de Brasil y de la idea del brasileño, se buscó comprender mejor los modos por los cuales dichos jóvenes, al mediar los mecanismos comunicativos propios del proceso de producción de identidades juveniles, interpretaban y resignificaban tal idea de pertenencia. De esta forma, mediante la utilización controlada de un blog de Internet, la investigación se dedicó a capturar los cambios en los modos de entender las realidades sociales. Se buscó comprender, en sus discursos, los cambios de sentidos entre los elementos de la cultura política constituidos en el ámbito del pensamiento social brasileño, así como aquello que se prescribe para ser enseñado en la historia escolar y los aspectos que pautan el esfuerzo de interpretación propio de las culturas juvenilesThe purpose of this article is to present the results of research carried out in connection with the programme of Post-Graduation in Education of the Federal University of Juiz de Fora, where the relationship between young Brazilians and meanings of national belonging was studied in its multiple senses and discursive spaces. Starting from the observation that young people, in school scenarios, tended to assume a tacit attitude of deprecation of Brazil and the idea of Brazilian, we sought to comprehend better the ways such young people, when affected by the communicative mechanisms characteristic of the juvenile identity production process, interpreted and ressignified this idea of belonging. With controlled use of an Internet blog, the research proceeded to capture changes in the ways of understanding social reality by looking at the shifts in meanings of elements of political culture established in the context of Brazilian social thinking, what is laid down to be taught in school in the subject of history, and the factors that govern the effort of interpretation characteristic of juvenile culture

Interventions in School Settings for Students With ADHD

This article consists of a review of 16 research studies on treatments in school settings for children with attention deficit hyperactivity disorder (ADHD) carried out in the last decade. It includes both simple interventions and multicomponent interventions where different techniques are combined. Based on this revision, the conclusion is drawn that, based on the evidence, school-based treatments for ADHD are effective in the short run for reducing disruptive behaviors and improving on-task behavior and academic performance of children with ADHD. Issues regarding the limitations to generalizing the improvements over time and across content areas are discussed. Furthermore, results from the MTA¿a study designed to compare the efficacy of behavioral treatment (BT), medical management (MM), combined treatment (BT and MM), and a routine community care control group¿are discussed. The MTA findings suggest that the most effective treatment for ADHD is a multimodal intervention that frequently includes concurrent medication in addition to parent training, school interventions, and child intervention

The stability and activity of human neuroserpin are modulated by a salt bridge that stabilises the reactive centre loop

Neuroserpin (NS) is an inhibitory protein belonging to the serpin family and involved in several pathologies, including the dementia Familial Encephalopathy with Neuroserpin Inclusion Bodies (FENIB), a genetic neurodegenerative disease caused by accumulation of NS polymers. Our Molecular Dynamics simulations revealed the formation of a persistent salt bridge between Glu289 on strand s2C and Arg362 on the Reactive Centre Loop (RCL), a region important for the inhibitory activity of NS. Here, we validated this structural feature by simulating the Glu289Ala mutant, where the salt bridge is not present. Further, MD predictions were tested in vitro by purifying recombinant Glu289Ala NS from E. coli. The thermal and chemical stability along with the polymerisation propensity of both Wild Type and Glu289Ala NS were characterised by circular dichroism, emission spectroscopy and non-denaturant gel electrophoresis, respectively. The activity of both variants against the main target protease, tissue-type plasminogen activator (tPA), was assessed by SDS-PAGE and chromogenic kinetic assay. Our results showed that deletion of the salt bridge leads to a moderate but clear reduction of the overall protein stability and activity

Childbirth as I see it.... or the way I wish it was? Expectations of pregnant women towards childbirth and obstetric care in the public health care system

Explicações para a elevação das taxas de cesárea em nosso país giraram em torno da forma como se organizou a assistência obstétrica, a formação dos profissionais de saúde e a demanda de cesarianas pelas parturientes. Neste trabalho nos propusemos a identificar as expectativas de gestantes em relação ao tipo de parto. Foram realizados três grupos focais em um hospital público na cidade de São Paulo. As categorias de análise foram: parto normal, fórceps, cesárea, pré-natal e assistência ao parto. Nesses grupos, pudemos identificar demanda por cesárea em multigestas associada ao desejo de laqueadura tubária e, mais que medo da dor do parto, as mulheres temiam as reações dos profissionais de saúde às suas queixas. Evidenciou-se deficiência de informações sobre questões da vida reprodutiva, todavia, a preferência era pelo parto vaginal, sendo a cesárea temida pelos riscos a ela associados. As autoras propõem a revisão da demanda das mulheres por cesárea como um dos fatores principais da escalada de partos cirúrgicos em nosso sistema de saúde. _______________________________________________________________________________________ ABSTRACTExplanations for increased cesarean section rates in Brazil have focused on the organization of obstetric care, training of health professionals, and women’s demand for surgical deliveries. This study aimed to identify pregnant women’s expectations towards childbirth. Three focus groups were conducted in a public hospital in the city of São Paulo. Analytical categories were: vaginal birth, forceps, c-section, prenatal care, and obstetric care. The desire for c-sections was associated with a demand for tubal ligation, and although women feared labor pains, they were more afraid of how the obstetric team might react to their complaints. Lack of information on reproductive issues was associated with a demand for more information. There was a preference for vaginal births, since most women feared c-sections due to risks associated with this surgical intervention. The authors propose that the demand for cesareans among women should be reconsidered as one of the main factors in the rise in surgical deliveries in the Brazilian health care system

Sobre o ato de aprender a olhar: a cidade como um jogo de saberes e potências educadoras

O objetivo deste artigo é discutir, sob inspiração do conceito de “autoridade compartilhada” de Frisch (2016), os impactos das reflexões contemporâneas e desafios da História Pública – considerando-se a potencialidade de suas ações e produções para a construção de possibilidades educativas escolares e não escolares. Nesse rastro, pretendo explorar suas equivalências epistemológicas em relação a perspectivas em composição no campo de pesquisa educacional, todas capazes de reduzir a ênfase “professorcêntrica” que nos cerca e produzir possibilidades educativas nas quais não só os sujeitos se encontrem em diálogos horizontalizados, como também possam abrir possibilidades múltiplas sob o ponto de vista de construções curriculares. Para tanto, um tema central ao exercício educativo impõe-se: o tema da Cidade, que será aqui abordado em sua potência educadora para múltiplos espaços educativos, sobretudo o espaço escolar, sob a perspectiva de um convite à experimentação, à ousadia e ao encontro, pela cidade, com múltiplos sujeitos, memórias, espaços e tempos

Bajo el signo de la memoria : Tiempo e historia en la relación entre cuadros de cultura y saberes docentes

Voy a basarme en el carácter de ejemplaridad de estas dos figuras mitológicas, Aurora y Jano, para tentar reflexionar, desde la investigación que originó mi tesis doctoral defendida junto a la Unicamp en 2004, qué tipo de relaciones teórico-metodológicas podemos establecer entre Memoria, Tiempo e Historia en una línea de investigación definida a saber, o sea, los procesos de construcción y transformación de los saberes docentes sobre la Historia que enseñan.Trabajo presentado en el Panel 5: Producciones, encuentros y conflictos en espacios educativos externos a la escuelaFacultad de Humanidades y Ciencias de la EducaciónSociedad Argentina de Historia de la Educación (SAHE

Giving order to the edge: a new framework : design of a station as a town center

Thesis (M.Arch.)--Massachusetts Institute of Technology, Dept. of Architecture, 2000.Includes bibliographical references (p. [98]-100).Fifty Years later, the San Juan periphery has become and edge city. The prediction was accurate. The challenge now is to correct this existing condition. This thesis is an exploration in developing a physical form to provide a framework that will organize the diverse parts. By exploring the connections within and edge city condition and defining a new town center, the thesis attempts to formulate a physical strategy that will give cohesion to the area through the infrastructure. The subject for this exploration is the design of the Degetau Station, a subway station along the Carolina Corridor, a new line that is part of the Tren Urbano, a heavy rail transit system currently being constructed in Puerto Rico. The investigation occurs at three scales: the urban, the site and the station. At the urban scale, the region will be seen as a new entertainment node. At the site scale, the area will be conceived as a new town and interchange transit center. At the architectural scale, the station will be perceived as a plaza, with strong connections between the landscape and a series of layered spaces that connects the subway to the street level.by Sonia M. Miranda-Palacios.M.Arch

Propuesta del Sistema de Gestión de Calidad y Control Estadístico del envasado para la línea de galletas de SOAL S.A.C.

Universidad Nacional Agraria La Molina. Facultad de Industrias Alimentarias. Departamento Académico de Ingeniería de Alimentos y Productos AgropecuariosSe propone un Sistema de gestión de la Calidad en base a la ISO 9001:2015 para la empresa SOAL SAC.; dedicada a elaborar y comercializar productos para el consumo humano, destinado exclusivamente a los programas sociales del gobierno peruano y Municipalidades. Con el fin de determinar y evaluar la gestión de la calidad en la que se encuentra la empresa, se aplicó la Encuesta de estimación de costos de calidad (IMECCA, 1994), la lista de verificación de los requisitos de higiene en plantas (FAO, 1995) y lista de verificación cuantitativa de la Norma ISO 9001:2015. En cuanto a la encuesta de IMECCA, seconcluyó que la empresa SOAL SAC, está ubicada dentro de la categoría de costos de calidad moderado, con un puntaje total de 140 puntos e indicador de costos de calidad de 8.5%; lo que indica que la empresa aplica una gestión orientada a la prevención. De la aplicación de la lista de verificación de los requisitos de higiene en plantas, la empresa obtuvo un nivel de cumplimiento “Regular”, con un porcentaje del 62.39%. Este calificativo se debe a la falta de cumplimiento con el programa de higiene y saneamiento. De la aplicación de la lista de verificación cuantitativa de la Norma ISO 9001:2015, la empresa SOAL SAC, obtiene un calificativo de “muy deficiente”, con un nivel de cumplimiento del 37.1%; demostrando de esta manera que no cuenta con un Sistema de Gestión de la Calidad. Se determinó el diagnóstico de la empresa, el cual permitió identificar los dos principales problemas de la empresa, condición que permitió elaborar las propuestas de mejora siguientes: Elaboración de un manual de la calidad y el Planteamiento de un Control Estadístico para el Proceso de Envasado de galletas de quinua. Se elaboró el mapa de interacción de procesos y se redactó los siguientes documentos: procedimientos, planes y formatos que están incluidos en el Manual de la calidad, siendo este manual, el soporte al Sistema de Gestión de la Calidad para SOAL SAC.A Quality Management System based on ISO 9001: 2015 is proposed for the company SOAL SAC; dedicated to elaborate and commercialize products for human consumption, destined exclusively to the social programs of the Peruvian government and Municipalities. In order to determine and evaluate the quality management in which the company is located, the Quality Cost Estimation Survey (IMECCA, 1994), the checklist of plant hygiene requirements (FAO, 1995) was applied. ) and quantitative checklist of ISO 9001: 2015. Regarding the IMECCA survey, it was concluded that the SOAL SAC company is located in the category of moderate quality costs, with a total score of 140 points and an indicator of quality costs of 8.5%; which indicates that the company applies a management oriented to prevention. From the application of the checklist of hygiene requirements in plants, the company obtained a level of compliance "Regular", with a percentage of 62.39%. This qualification is due to the lack of compliance with the hygiene and sanitation program. From the application of the quantitative checklist of ISO 9001: 2015, the company SOAL SAC, obtains a qualification of “very poor”, with a level of compliance of 37.1%; thus demonstrating that it does not have a Quality Management System. The diagnosis of the company was determined, which allowed identifying the two main problems of the company, a condition that allowed the development of the following improvement proposals: Preparation of a quality manual and the Approach to Statistical Control for the Packaging Process of quinoa cookies. The process interaction map was prepared and the following documents were drafted: procedures, plans and formats that are included in the Quality Manual, this manual being the support for the Quality Management System for SOAL SAC