52 research outputs found

    Study for the analysis of the observations, and numerical data representing the planets as far-infrared calibration sources

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    The existing radiative transfer and inversion programs will be modified for application to the atmospheres of Uranus, Neptune, and Jupiter. The programs will be employed for analysis of KAO planetary observations in order to develop far infrared photometric calibration standards. This work will be carried out on MSFC computers. The expected end product of this task is a working program for analysis of the observations, and numerical data representing the planets as far-infrared calibration sources

    Investigation of the horizontal collision damage behavior of fruit during transporting based on a new instrumented impactor

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    Horizontal collisions between fruit and rigid walls are a common occurrence in postharvest packaging and transportation. To address this issue, a novel high-precision instrumented impactor was developed, comprising a high-speed imaging system, an ejection device, and a force sensor. Results showed that the impactor was able to effectively simulate the horizontal collision process between various small spherical fruits (such as cherry tomatoes, plums, sweet cherries, and winter jujubes) and packaging materials at three velocities: slow, medium, and high. Output parameters included the impact force and impact time of the fruit acting on each packaging material, as well as the displacement, displacement rate, impact energy, rebound energy, and absorption energy of the fruit. During the horizontal collision simulation, it was observed that the winter jujube exhibited the largest impact force and the shortest impact time among the four types of fruit tested. Conversely, the sweet cherry demonstrated the lowest proportion of damage area when colliding with the EPE board compared to the rigid board and foam board. This study presents a powerful tool for investigating the horizontal collision behaviour between fruit and rigid plates

    Herbal Compound “Jiedu Huayu” Reduces Liver Injury in Rats via Regulation of IL-2, TLR4, and PCNA Expression Levels

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    Aim of the Study. To investigate the preventative effects of Jiedu Huayu (JDHY) on D-galactosamine (D-GalN) and lipopolysaccharide-induced acute liver failure (ALF) and to evaluate the possible mechanisms of action. Materials and Methods. ALF was induced in Wistar rats by administrating D-GalN (900 mg/kg) and lipopolysaccharide (10 μg/kg). After treatment with JDHY granules, the levels of blood alanine aminotransferase, aspartate aminotransferase, total bilirubin, and prothrombin time were determined. Proliferating cell nuclear antigen was detected by immunohistochemistry staining. The expression of interleukin-2 (IL-2) and toll-like receptor 4 (TLR4) was examined by fluorescence quantitative reverse transcription polymerase chain reaction (qRT-PCR) and Western blot. Results. JDHY treatment dramatically improved liver function and increased survival rates in an ALF model in rats. We observed a decrease in IL-2 and TLR4 expression following treatment with JDHY in liver cells from ALF rats using qRT-PCR and Western blot analysis. Conclusion. We hypothesize that the therapeutic potential of JDHY for treating ALF is due to its modulatory effect on the suppression of inflammation and by promoting hepatocyte regeneration. Our results contribute towards validation of the traditional use of JDHY in the treatment of liver disease

    IDH1突变体通过抑制JNK的激活减少生长因子缺失诱导的细胞凋亡

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    文章简介抵抗凋亡和能在血清营养因子缺乏的情况下生长是肿瘤细胞的两个主要特征。JNK的激活是血清饥饿诱导的细胞凋亡所必须的因素。目前研究表明IDH1突变体产生的致癌代谢物2-羟基戊二酸(2-HG)是突变的导致肿瘤形成的主要原因。然而目前尚不清楚2-HG是否能抑制JNK的激活,进而使细胞抵抗血清饥饿诱导的凋亡。课题组以IDH1 R132Q的基因敲入MEF为研究对象

    DESIGN OF A TRISO PARTICLE FUEL BASED INTEGRATED GAS-COOLED SPACE NUCLEAR REACTOR

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    According to versatile and long-lasting requirements of deep space missions, space nuclear reactor (SNR) power system is becoming a more suitable choice compared to traditional solar and chemical power systems in large-scale and long-life applications. From NASA’s previous research, the gas-cooled reactor along with closed Brayton cycle (CBC) could achieve optimized weight-power ratio and be more applicable for large power system (100 kWe or MWe level). In this paper, a concept of integrated gas-cooled space nuclear reactor named IGCR-200 is introduced, which is designed based on the TRISO particle fuel and could achieve 200 kWe output combined with highly efficient He/Xe CBC generator. The design requirements include an operation lifetime of at least 10 years in full power mode, maximum fuel temperature < 1600K, negative temperature reactivity feedback, passive decay heat removal, redundancy in reactor control, and sub-criticality during water flooding accidents. It has an outer diameter of 70.0 cm, a height of 66.0 cm (reactor part), a total mass around 1000 kg, total Uranium inventory of 226.8 kg (235U enrichment as 93%), and 1 MW thermal power output. The reactor physics, thermal hydraulics and other required analysis are taken out to show the feasibility and performances of the design

    The corrosion mechanism of the sintered (Ce, Nd)-Fe-B magnets prepared by double main phase and single main phase approaches

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    The sintered (Ce, Nd)-Fe-B magnets were produced widely by Double Main Phase (DMP) method in China as the magnetic properties of the DMP magnets are superior to those of single main phase (SMP) magnets with the same nominal composition. In this work, the microstructure and corrosion mechanism of the sintered (Ce0.2Nd0.8)30FebalB (wt.%) magnets prepared by DMP and SMP method were studied in detail. Compared to SMP magnets, the DMP magnets have more positive corrosion potential, lower corrosion current density, larger electron transfer resistance, and lower mass loss of the free corrosion experiment in 0.5mol/l Na2SO4 aqueous solution. All of the results show that the DMP magnets have better corrosion resistance than SMP magnets. The back scattered electron images show that the crystalline grains of the DMP magnets are sphericity with a smooth surface while the SMP ones have plenty of edges and corners. Besides, the distribution of Ce/Nd is much more uneven in both magnetic phase and rare earth (Re)-rich phase of the DMP magnets than those of SMP magnets. After corrosion, DMP magnets show eroded magnetic phase and intact Re-rich phase, which indicate that galvanic corrosion of the Re-rich phase acting as the cathode appears
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