1,677 research outputs found
Three-dimensional charge transport mapping by two-photon absorption edge transient-current technique in synthetic single-crystalline diamond
We demonstrate the application of two-photon absorption transient current
technique to wide bandgap semiconductors. We utilize it to probe charge
transport properties of single-crystal Chemical Vapor Deposition (scCVD)
diamond. The charge carriers, inside the scCVD diamond sample, are excited by a
femtosecond laser through simultaneous absorption of two photons. Due to the
nature of two-photon absorption, the generation of charge carriers is confined
in space (3-D) around the focal point of the laser. Such localized charge
injection allows to probe the charge transport properties of the semiconductor
bulk with a fine-grained 3-D resolution. Exploiting spatial confinement of the
generated charge, the electrical field of the diamond bulk was mapped at
different depths and compared to an X-ray diffraction topograph of the sample.
Measurements utilizing this method provide a unique way of exploring spatial
variations of charge transport properties in transparent wide-bandgap
semiconductors.Comment: This article may be downloaded for personal use only. Any other use
requires prior permission of the author and AIP Publishing. The following
article appeared in Applied Physics Letters and may be found at
https://doi.org/10.1063/1.509085
Bias dependence and bistability of radiation defects in silicon
Influence of bias on effective dopant concentration in neutron and pion irradiated diodes has been measured. Detailed studies of annealing of the bias-induced damagehave revealed three components, with introduction rates from 0.005 to 0.008 cm andannealing time constants ranging from 5 to 1000 hours at 20C. Variation of annealing temperatures yielded activation energies around 1 eV for all the three components. Bistable behavior of radiation damage under bias has been observed and its activation and annealingstudied. The bistable damage was associated to the fastest annealing component of bias-induced damage.Using the parameterization obtained, a prediction for ATLAS SCT operation was made.Bias-induced damage is shown to require an additional 80 V to fully deplete detectors at the end of LHC operation
Large-scale analysis of cell cycle regulators in urothelial bladder cancer identifies p16 and p27 as potentially useful prognostic markers
AIMS: We investigated the value of multiple cell cycle markers for their prognostic impact on overall survival and recurrence-free survival in urothelial carcinoma (UC). METHODS: A tissue microarray consisting of 99 UCs was evaluated for the expression of p53, p16, p21, p27, cyclin D1, cyclin E , Bcl-2, Ki-67 and PCNA. Statistical analysis was performed applying Kaplan-Meier and Cox regression models using receiver operator characteristic curves for determination of markers' cutoffs. RESULTS: Expression above the cutoffs of Ki-67, p53 and p27, particularly in high-grade and early-stage UC, was associated with worse overall survival, while expression of p16 indicated a better outcome in low-grade and low-stage tumors. Recurrence-free survival was better in patients with high-grade UC expressing PCNA, p16 and cyclin E, and low-grade UC expressing Bcl-2 above the cutoffs, but worse in all tumors with high Ki-67. CONCLUSION: Cell cycle deregulation in UC is complex and the prognostic value of the various involved proteins should be differentially regarded with respect to this complexity and other tumor characteristics such as grade and stage. Our results point towards the role of p16- and p27-associated pathways in tumor progression and indicate that, by using standardized approaches for tissue antigen expression, evaluation and cutoff determination, single potentially useful prognostic markers could be identified
Radiation Hardness of Thin Low Gain Avalanche Detectors
Low Gain Avalanche Detectors (LGAD) are based on a n++-p+-p-p++ structure
where an appropriate doping of the multiplication layer (p+) leads to high
enough electric fields for impact ionization. Gain factors of few tens in
charge significantly improve the resolution of timing measurements,
particularly for thin detectors, where the timing performance was shown to be
limited by Landau fluctuations. The main obstacle for their operation is the
decrease of gain with irradiation, attributed to effective acceptor removal in
the gain layer. Sets of thin sensors were produced by two different producers
on different substrates, with different gain layer doping profiles and
thicknesses (45, 50 and 80 um). Their performance in terms of gain/collected
charge and leakage current was compared before and after irradiation with
neutrons and pions up to the equivalent fluences of 5e15 cm-2. Transient
Current Technique and charge collection measurements with LHC speed electronics
were employed to characterize the detectors. The thin LGAD sensors were shown
to perform much better than sensors of standard thickness (~300 um) and offer
larger charge collection with respect to detectors without gain layer for
fluences <2e15 cm-2. Larger initial gain prolongs the beneficial performance of
LGADs. Pions were found to be more damaging than neutrons at the same
equivalent fluence, while no significant difference was found between different
producers. At very high fluences and bias voltages the gain appears due to deep
acceptors in the bulk, hence also in thin standard detectors
Evaluating GAIA performances on eclipsing binaries. II. Orbits and stellar parameters for V781 Tau, UV Leo and GK Dra
The orbits and physical parameters of three close, double-lined G0 eclipsing
binaries have been derived combining H_P, V_T, B_T photometry from the
Hipparcos/Tycho mission with 8480-8740 \AA ground-based spectroscopy. The setup
is mimicking the photometric and spectroscopic observations that should be
obtained by GAIA. The binaries considered here are all of G0 spectral type, but
each with its own complications: V781 Tau is an overcontact system with
components of unequal temperature, UV Leo shows occasional surface spots and GK
Dra contains a delta-Scuti variable. Such peculiarities will be common among
binaries to be discovered by GAIA. We find that the values of masses, radii and
temperatures for such stars can be derived with a 1-2% accuracy using the
adopted GAIA-like observing mode.Comment: accepted for publication in Astronomy and Astrophysics, contains 5
Tables and 3 Figures; correction of an important typ
Using Early Data to Illuminate the Pioneer Anomaly
Analysis of the radio tracking data from the Pioneer 10/11 spacecraft at
distances between about 20 - 70 AU from the Sun has consistently indicated the
presence of an unmodeled, small, constant, Doppler blue shift drift of order 6
\times 10^{-9} Hz/s. After accounting for systematics, this drift can be
interpreted as a constant acceleration of a_P= (8.74 \pm 1.33) \times 10^{-8}
cm/s^2 directed towards the Sun, or perhaps as a time acceleration of a_t =
(2.92 \pm 0.44)\times 10^{-18} s/s^2. Although it is suspected that there is a
systematic origin to this anomaly, none has been unambiguously demonstrated. We
review the current status of the anomaly, and then point out how the analysis
of early data, which was never analyzed in detail, could allow a more clear
understanding of the origin of the anomaly, be it a systematic or a
manifestation of unsuspected physics.Comment: 19 pages, 6 figures, 2 tables, additional materia
Fast Polycrystalline-CdTe Detectors for LHC Luminosity Measurements
Beam diagnostics in future high-energy accelerators will require long lived instrumentation in highly hostile radiation environments. A research program aiming at individuating new solutions and testing them under extreme operational conditions has been launched at CERN in the framework of developments for the LHC instrumentation. Its outcome might be used in future accelerator projects, in industry or in physics applications. The detectors which will be adopted for the LHC luminosity monitoring and optimization will be installed close to or inside copper absorbers specifically designed for radiation protection of the accelerator magnetic elements in the interaction regions. These detectors will have to withstand extreme radiation levels and their long-term operation has to be assured without requiring human intervention. Polycrystalline-CdTe detectors have demonstrated their radiation hardness against extreme doses of X-ray exposure in the LEP collider and are considered as good candidates for LHC luminosity monitoring applications. After recalling a series of measurements obtained on CdTe samples exposed to different sources to study their time response and sensitivity we present results on their performance after irradiation at doses of 10^16 neutrons/cm^2. This is a preliminary step in the program intended to test the samples during and after irradiation up to levels of 10^18 neutrons/cm^2 and 10^16 protons/cm^2 comparable to those anticipated at the detector locations over ten years of operation of the accelerator
SN 2007od: A Type IIP SN with Circumstellar Interaction
SN 2007od exhibits characteristics that have rarely been seen in a Type IIP
supernova (SN). Optical V band photometry reveals a very steep brightness
decline between the plateau and nebular phases of ~4.5 mag, likely due to SN
2007od containing a low mass of 56Ni. The optical spectra show an evolution
from normal Type IIP with broad Halpha emission, to a complex, four component
Halpha emission profile exhibiting asymmetries caused by dust extinction after
day 232. This is similar to the spectral evolution of the Type IIn SN 1998S,
although no early-time narrow (~200 km s-1) Halpha component was present in SN
2007od. In both SNe, the intermediate-width Halpha emission components are
thought to arise in the interaction between the ejecta and its circumstellar
medium (CSM). SN 2007od also shows a mid-IR excess due to new dust. The
evolution of the Halpha profile and the presence of the mid-IR excess provide
strong evidence that SN 2007od formed new dust before day 232. Late-time
observations reveal a flattening of the visible lightcurve. This flattening is
a strong indication of the presence of a light echo, which likely accounts for
much of the broad, underlying Halpha component seen at late-times. We believe
the multi-peaked Halpha emission is consistent with the interaction of the
ejecta with a circumstellar ring or torus (for the inner components at \pm1500
km s-1), and a single blob or cloud of circumstellar material out of the plane
of the CSM ring (for the outer component at -5000 km s-1). The most probable
location for the formation of new dust is in the cool dense shell created by
the interaction between the expanding ejecta and its CSM. Monte Carlo radiative
transfer modeling of the dust emission from SN 2007od implies that up to 4x
10-4Msun of new dust has formed. This is similar to the amounts of dust formed
in other CCSNe such as SNe 1999em, 2004et, and 2006jc.Comment: 35 pages, 6 figures. Accepted for publication in Ap
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