INSTITUTE OF PHYSICS PUBLISHING PHYSICS IN MEDICINE AND BIOLOGY

Improved image contrast of calcifications in breas

Human Breast Cancer Specimens: Diffraction-enhanced Imaging with Histologic Correlation—Improved Conspicuity of Lesion Detail Compared with Digital Radiography

Seven breast cancer specimens were examined with diffraction-enhanced imaging at 18 keV with a silicon crystal with use of the silicon 333 reflection in Bragg mode. Images were compared with digital radiographs of the specimen, and regions of increased detail were identified. Six of the seven cases (86%) showed enhanced visibility of surface spiculation that correlated with histopathologic information, including extension of tumor into surrounding tissue

WS-PGRADE/gUSE Generic DCI Gateway Framework for a Large Variety of User Communities

The WS-PGRADE/gUSE generic DCI gateway framework has been developed to support a large variety of user communities. It provides a generic purpose, workflow-oriented graphical user interface to create and run workflows on various DCIs including clusters, Grids, desktop Grids and clouds. The framework can be used by NGIs to support small user communities who cannot afford to develop their own customized science gateway. The WS- PGRADE/gUSE framework also provides two API interfaces (Application Specific Module API and Remote API) to create application-specific science gateways according to the needs of different user communities. The paper describes in detail the workflow concept of WS-PGRADE, the DCI Bridge service that enables access to most of the popular European DCIs and the Application Specific Module and Remote API concepts to generate application-specific science gateways. © 2012 Springer Science+Business Media Dordrecht