Overconstrained dynamics in galaxy redshift surveys

The least-action principle (LAP) method is used on four galaxy redshift surveys to measure the density parameter Omega_m and the matter and galaxy-galaxy power spectra. The datasets are PSCz, ORS, Mark III and SFI. The LAP method is applied on the surveys simultaneously, resulting in an overconstrained dynamical system that describes the cosmic overdensities and velocity flows. The system is solved by relaxing the constraint that each survey imposes upon the cosmic fields. A least-squares optimization of the errors that arise in the process yields the cosmic fields and the value of Omega_m that is the best fit to the ensemble of datasets. The analysis has been carried out with a high-resolution Gaussian smoothing of 500 km/s and over a spherical selected volume of radius 9,000 km/s. We have assigned a weight to each survey, depending on their density of sampling, and this parameter determines their relative influence in limiting the domain of the overall solution. The influence of each survey on the final value of Omega_m, the cosmographical features of the cosmic fields and the power spectra largely depends on the distribution function of the errors in the relaxation of the constraints. We find that PSCz and Mark III are closer to the final solution than ORS and SFI. The likelihood analysis yields Omega_m= 0.37\pm 0.01 to 1sigma level. PSCz and SFI are the closest to this value, whereas ORS and Mark III predict a somewhat lower Omega_m. The model of bias employed is a scale-dependent one, and we retain up to 42 bias coefficients b_{rl} in the spherical harmonics formalism. The predicted power spectra are estimated in the range of wavenumbers 0.02-0.49h Mpc^{-1}, and we compare these results with measurements recently reported in the literature.Comment: 10 pages, no figure

Trasplante óseo

We describe the methodology of the Bone and Soft Tissue Bank, from extraction and storage until use. Since the year 1986, with the creation of the Bone Bank in the University Clinic of Navarra, more than 3,000 grafts have been used for very different types of surgery. Bone grafts can be classified into cortical and spongy; the former are principally used in surgery to save tumour patients, in large post-traumatic reconstructions and in replacement surgery where there are massive bone defects and a structural support is required. The spongy grafts are the most used due to their numerous indications; they are especially useful in filling cavities that require a significant quantity of graft when the autograft is insufficient, or as a complement. They are also of special help in treating fractures when there is bone loss and in the treatment of delays in consolidation and pseudoarthrosis in little vascularized and atrophic zones. They are also used in prosthetic surgery against the presence of cavity type defects. Allografts of soft tissues are specially recognised in multiple ligament injuries that require reconstructions. Nowadays, the most utilised are those employed in surgery of the anterior cruciate ligament although they can be used for filling any ligament or tendon defect. The principal difficulties of the cortical allografts are in the consolidation of the ends with the bone itself and in tumour surgery, given that these are patients immunodepressed by the treatment, the incidence of infection is increased with respect to spongy grafts and soft tissues, which is irrelevant. In short, the increasingly widespread use of allografts is an essential therapeutic weapon in orthopaedic surgery and traumatology. It must be used by expert hands

Hybrid quantization of an inflationary universe

We quantize to completion an inflationary universe with small inhomogeneities in the framework of loop quantum cosmology. The homogeneous setting consists of a massive scalar field propagating in a closed, homogeneous scenario. We provide a complete quantum description of the system employing loop quantization techniques. After introducing small inhomogeneities as scalar perturbations, we identify the true physical degrees of freedom by means of a partial gauge fixing, removing all the local degrees of freedom except the matter perturbations. We finally combine a Fock description for the inhomogeneities with the polymeric quantization of the homogeneous background, providing the quantum Hamiltonian constraint of the composed system. Its solutions are then completely characterized, owing to the suitable choice of quantum constraint, and the physical Hilbert space is constructed. Finally, we consider the analog description for an alternate gauge and, moreover, in terms of gauge-invariant quantities. In the deparametrized model, all these descriptions are unitarily equivalent at the quantum level.Comment: 16 pages, no figure

Unique Fock quantization of scalar cosmological perturbations

We investigate the ambiguities in the Fock quantization of the scalar perturbations of a Friedmann-Lema\^{i}tre-Robertson-Walker model with a massive scalar field as matter content. We consider the case of compact spatial sections (thus avoiding infrared divergences), with the topology of a three-sphere. After expanding the perturbations in series of eigenfunctions of the Laplace-Beltrami operator, the Hamiltonian of the system is written up to quadratic order in them. We fix the gauge of the local degrees of freedom in two different ways, reaching in both cases the same qualitative results. A canonical transformation, which includes the scaling of the matter field perturbations by the scale factor of the geometry, is performed in order to arrive at a convenient formulation of the system. We then study the quantization of these perturbations in the classical background determined by the homogeneous variables. Based on previous work, we introduce a Fock representation for the perturbations in which: (a) the complex structure is invariant under the isometries of the spatial sections and (b) the field dynamics is implemented as a unitary operator. These two properties select not only a unique unitary equivalence class of representations, but also a preferred field description, picking up a canonical pair of field variables among all those that can be obtained by means of a time-dependent scaling of the matter field (completed into a linear canonical transformation). Finally, we present an equivalent quantization constructed in terms of gauge-invariant quantities. We prove that this quantization can be attained by a mode-by-mode time-dependent linear canonical transformation which admits a unitary implementation, so that it is also uniquely determined.Comment: 19 pages, minor impovementes included, typos correcte

Racetrack Potentials and the de Sitter Swampland Conjectures

We show that one can find de Sitter critical points (saddle points) in models of flux compactification of Type IIB String Theory without any uplifting terms and in the presence of several moduli. We demonstrate this by giving explicit examples following some of the ideas recently presented by Conlon in [1], as well as more generic situations where one can violate the strong form of the de Sitter Swampland Conjecture. We stabilize the complex structure and the dilaton with fluxes, and we introduce a racetrack potential that fixes the K\"ahler moduli. The resultant potentials generically exhibit de Sitter critical points and satisfy several consistency requirements such as flux quantization, large internal volume, and weak coupling, as well as a form of the so-called Weak Gravity Conjecture. Furthermore, we compute the form of the potential around these de Sitter saddle points and comment on these results in connection to the refined and more recent version of the de Sitter Swampland Conjecture.Comment: 23 pages, 4 figures; updated to reflect version accepted to JHE

Reduction of Murine Cutaneous UVB-Induced Tumor-Infiltrating T Lymphocytes by Dietary Canthaxanthin

The effect of dietary canthaxanthin, retinyl palmitate, or their combination on the tumor-infiltrating T-lymphocyte response (T-TIL) in de novo murine ultraviolet type B irradiation-induced tumors was investigated to elucidate potential mechanisms of action of these compounds. We found that dietary canthaxanthin greatly reduced the number of tumor-infiltrating helper/inducer, suppressor/cytotoxic, and interleukin-2 receptor-positive T lymphocytes and also observed a concomitant statistically significant increase in tumour incidence in canthaxanthin-fed animals. The addition of retinyl palmitate to the canthaxanthin diet ameliorated this negative effect on TIL and the development of skin tumors. We conclude that dietary retinyl palmitate and canthaxanthin can modulate the host T-cell immune response within a growing tumor and may affect tumorigenicity