141 research outputs found

    Probing nucleon-nucleon correlations in heavy-ion transfer reactions

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    Pair correlations have been investigated in heavy-ion collisions via studies of the transfers of different nucleon pairs. In particular, excitation functions of one- and two-neutron transfer channels have been measured for the closed shell 40Ca + 96Zr and superfluid 60Ni + 116Sn systems from the Coulomb barrier energy to energies far below. By using the unique performance of the magnetic spectrometer PRISMA, in terms of resolution and efficiency, measurements at very low bombarding energies have been performed. The experimental transfer probabilities have been compared with semiclassical microscopic calculations that incorporate nucleonnucleon correlations, together with known structure information of entrance and exit channels nuclei and reaction dynamics. These calculations well reproduce, in the whole energy range, one- and two-neutron transfer channels in shape and magnitude

    Karakterizacija polimernih nanofiltracijskih membrana

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    As membrane processes are increasingly used in industrial applications, there is a growing interest in methods of membrane characterization. Traditional membrane characteristics, such as cut-off value and pore size distribution, are being supplemented by membrane surface characteristics, such as charge density or zeta potential and hydrophobicity. This study, therefore, characterizes the three different polymeric membranes used (NFT-50, DL and DK). The molecular mass cut-off (MMCO) value was determined using a set of reference solutes within the molecular range 150-600 Da, whereas streaming potential measurements enabled quantification of the surface charge characteristics. Hydrophobicity was studied using contact angle measurements. The results indicated that even though all three membranes had very similar layer compositions which consisted of poly(piperazneamide), as top layers they showed different values of measured quantitive. The NFT-50 membrane had the lowest MMCO value and the most hydrophilic membrane surface, followed by DK and DL. Membrane fouling as measured by flux reduction was determined by streaming potential measurements and accompanied by a positive change in zeta potential.Znanstvena istraživanja metoda za karakterizaciju membrana za pročišćavanje otpadnih voda u stalnom su porastu. Tradicionalne metode karakterizacije veličinom i raspodijelom pora dopunjuju se metodama karakterizacije određivanjem zeta-potencijala i hidrofilno/hidrofobnih svojstva. Stoga su u ovom radu karakterizirane tri različite polimerne nanofiltracijske membrane NFT-50, DL i DK karakterizirane veličinom MMCO odabirom tri referentne otopine molekulske mase 150-600 Da. Elektrokinetičke karakteristike tih membrana vrednovane su pomoću potencijala strujanja a hidrofobnost pomoću kontaktnog kuta. Rezultati istraživanja ukazuju na to da su, unatoč gotovo jednakom gornjem sloju kompozitnih membrana, mjerne veličine različite. Najnižu MMCO vrijednost i najvišu hidrofilnost ima NFT-50 membrana kojoj slijede DK i DL. Smanjivanje protoka permeata ukazuje na začepljivanje membrana, koje je izmjereno pomoću potencijala strujanja te rezultiralo smanjivanjem zeta-potencijala

    Oscillations above the barrier in the fusion of 28Si + 28Si

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    Fusion cross sections of 28Si + 28Si have been measured in a range above the barrier with a very small energy step (DeltaElab = 0.5 MeV). Regular oscillations have been observed, best evidenced in the first derivative of the energy-weighted excitation function. For the first time, quite different behaviors (the appearance of oscillations and the trend of sub-barrier cross sections) have been reproduced within the same theoretical frame, i.e., the coupled-channel model using the shallow M3Y+repulsion potential. The calculations suggest that channel couplings play an important role in the appearance of the oscillations, and that the simple relation between a peak in the derivative of the energy-weighted cross section and the height of a centrifugal barrier is lost, and so is the interpretation of the second derivative of the excitation function as a barrier distribution for this system, at energies above the Coulomb barrier.Comment: submitted to Physics Letters

    Anticancer Potential of Xanthohumol and Isoxanthohumol Loaded into SBA-15 Mesoporous Silica Particles against B16F10 Melanoma Cells

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    Xanthohumol (XN) and isoxanthohumol (IXN), prenylated flavonoids from Humulus lupulus, have been shown to possess antitumor/cancerprotective, antioxidant, antiinflammatory, and antiangiogenic properties. In this study, mesoporous silica (SBA-15) was loaded with different amounts of xanthohumol and isoxanthohumol and characterized by standard analytical methods. The anticancer potential of XN and IXN loaded into SBA-15 has been evaluated against malignant mouse melanoma B16F10 cells. When these cells were treated with SBA-15 containing xanthohumol, an increase of the activity correlated with a higher immobilization rate of XN was observed. Considering the amount of XN loaded into SBA-15 (calculated from TGA), an improved antitumor potential of XN was observed (IC50 = 10.8 ± 0.4 and 11.8 ± 0.5 µM for SBA-15|XN2 and SBA-15|XN3, respectively; vs. IC50 = 18.5 ± 1.5 µM for free XN). The main mechanism against tumor cells of immobilized XN includes inhibition of proliferation and autophagic cell death. The MC50 values for SBA-15 loaded with isoxanthohumol were over 300 µg/mL in all cases investigated. © 2022 by the authors

    Fusion of 28Si + 28Si: oscillations above the barrier and the behavior down to 1μb

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    Fusion excitation functions of light heavy-ion systems show oscillatory structures above the Coulomb barrier, caused by resonances or due to the penetration of successive centrifugal barriers well separated in energy. In heavier systems, the amplitude of oscillations decreases and the peaks get nearer to each other. This makes the measurements very challenging. We have performed a first experiment for 28Si + 28Si, by measuring fusion cross sections (σ) in an energy range of ≃15 MeV above the barrier, with a small ΔElab = 0.5 MeV step. Three regular oscillations are clearly observed, which are best revealed by plotting the energy-weighted derivative of the excitation function. The excitation function has been recently measured down to cross sections ≤1μb with larger energy steps. Coupled-channel (CC) calculations based on a shallow potential in the entrance channel are able to reproduce the oscillations. A further analysis will provide a stringent test for the calculations, in particular for the choice of the ion-ion potential, because the subbarrier excitation function has to be reproduced as well. Coupled-channel (CC) calculations based on a shallow potential in the entrance channel are able to reproduce the oscillations. A further analysis will provide a stringent test for the calculations, in particular for the choice of the ion-ion potential, because the subbarrier excitation function has to be reproduced as well

    Spectroscopy of proton-rich 79Zr : Mirror energy differences in the highly-deformed fpg shell

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    Energy differences between isobaric analogue states have been extracted for the A=79, 79Zr/79Y mirror pair following their population via nucleon-knockout reactions from intermediate-energy rare-isotope beams. These are the heaviest nuclei where such measurements have been made to date. The deduced mirror energy differences (MED) are compared with predictions from a new density-functional based approach, incorporating isospin-breaking effects of both Coulomb and nuclear charge-symmetry breaking and configuration mixing

    Establishing the Maximum Collectivity in Highly Deformed N=Z Nuclei

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    The lifetimes of the first excited 2^{+} states in the N=Z nuclei ^{80}Zr, ^{78}Y, and ^{76}Sr have been measured using the γ-ray line shape method following population via nucleon-knockout reactions from intermediate-energy rare-isotope beams. The extracted reduced electromagnetic transition strengths yield new information on where the collectivity is maximized and provide evidence for a significant, and as yet unexplained, odd-odd vs even-even staggering in the observed values. The experimental results are analyzed in the context of state-of-the-art nuclear density-functional model calculations

    Lifetime measurements of N ≃ 20 phosphorus isotopes using the AGATA γ-ray tracking spectrometer

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    International audienceLifetimes of excited states of the phosphorus isotopes 1533,34,35,36P have been measured by using the differential recoil-distance method. The isotopes of phosphorus were populated in binary grazing reactions initiated by a beam of S36 ions of energy 225 MeV incident on a thin Pb208 target mounted in the Cologne plunger apparatus. The combination of the PRISMA magnetic spectrometer and an early implementation of the AGATA γ-ray tracking array was used to detect γ rays in coincidence with projectile-like nuclear species. Lifetime measurements of populated states were made within the range from about 1 to 100 ps. The number of states for which lifetime measurements were possible was limited by statistics. For P33, lifetime limits were determined for the first 3/2+ and 5/2+ states at 1431 and 1848 keV, respectively; the results are compared with previous published lifetime values. The lifetime of the first 2+ state of P34 at 429 keV was determined and compared with earlier measurements. For P35, the states for which lifetimes, or lifetime limits, were determined were those at 2386, 3860, 4101, and 4493 keV, with Jπ values of 3/2+, 5/2+, 7/21−, and 7/22−, respectively. There have been no previous published lifetimes for states in this nucleus. A lifetime was measured for the stretched π(1f7/2)⊗ν(1f7/2)Jπ=(7+) state of P36 at 5212 keV and a lifetime limit was established for the stretched π(1d3/2)⊗ν(1f7/2)Jπ=(5−) state at 2030 keV. There are no previously published lifetimes for states of P36. Measured lifetime values were compared with the results of state-of-the-art shell-model calculations based on the PSDPF effective interaction. In addition, measured branching ratios, published mixing ratios, and electromagnetic transition rates, where available, have been compared with shell-model values. In general, there is good agreement between experiment and the shell model; however there is evidence that the shell-model values of the M1 transition rates for the 3/21+→1/2+ (ground state) and 5/21+→3/21+ transitions in P33 underestimate the experimental values by a factor between 5 and 10. In P35 there are some disagreements between experimental and shell-model values of branching ratios for the first and second excited 7/2− states. In particular, there is a serious disagreement for the decay characteristics of the second 7/2− state at 4493 keV, for which the shell-model counterpart lies at 4754 keV. In this case, the shell-model competing electromagnetic decay branches are dominated by E1 and M1 transitions

    Beyond Traditional Use of Alchemilla vulgaris: Genoprotective and Antitumor Activity In Vitro

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    Alchemilla vulgaris L. (lady’s mantle) was used for centuries in Europe and Balkan countries for treatments of numerous conditions and diseases of the reproductive system, yet some of the biological activities of lady’s mantle have been poorly studied and neglected. The present study aimed to estimate the potential of A. vulgaris ethanolic extract from Southeast Serbia to prevent and suppress tumor development in vitro, validated by antioxidant, genoprotective, and cytotoxic properties. A total of 45 compounds were detected by UHPLC–HRMS analysis in A. vulgaris ethanolic extract. Measurement of antioxidant activity revealed the significant potential of the tested extract to scavenge free radicals. In addition, the analysis of micronuclei showed an in vitro protective effect on chromosome aberrations in peripheral human lymphocytes. A. vulgaris extract strongly suppressed the growth of human cell lines derived from different types of tumors (MCF-7, A375, A549, and HCT116). The observed antitumor effect is realized through the blockade of cell division, caspase-dependent apoptosis, and autophagic cell death. Our study has shown that Alchemilla vulgaris L. is a valuable source of bioactive compounds able to protect the subcellular structure from damage, thus preventing tumorigenesis as well as suppressing tumor cell growth. © 2022 by the authors
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