Koronarokoteturvallisuus : Yhteenvetoraportti ajalta 1.1.2021-31.12.2022 : Kooste Terveyden ja hyvinvoinnin laitoksen lakisääteisen tehtävän toteuttamisesta

Koronapandemian aikana Terveyden ja hyvinvoinnin laitoksessa (THL) toteutettiin lukuisia koronapandemian edellyttämiä toimintoja työryhmissä, joihin osallistui THL:n asiantuntijoita myös infektiotauteihin ja rokottamiseen liittyvän työn ulkopuolelta. Yksi THL:n lakisääteisistä tehtävistä on rokotteiden haittavaikutusten selvittäminen. Koronarokotusten alettua Suomessa loppuvuodesta 2020 THL:ssä perustettiin työryhmä, joka sai tehtäväkseen tämän viranomaisvelvollisuuden toteuttamisen koronarokotusten osalta. Tässä yhteenvetoraportissa kuvataan koronarokoteturvallisuustyöryhmän työtä 1.1.2021 31.12.2022 väliseltä ajalta keskittyen kuvailemaan työtapoja sekä saavutettuja tuloksia

Noro- and rotavirus detections in children during COVID-19 pandemic—A nationwide register study in Finland

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The impact of the lockdown and the re-opening of schools and day cares on the epidemiology of SARS-CoV-2 and other respiratory infections in children : A nationwide register study in Finland

Background: Nationwide restrictions started in Finland in March to prevent the spread of COVID-19, leading to school and day care closures. The aim of this study is to describe the effect of closures and re-openings on the respiratory pathogen epidemiology. Methods: Laboratory-confirmed cases of SARS-CoV-2; respiratory syncytial virus (RSV); influenza (A & B); parainfluenza-, adeno-, and rhinoviruses; Mycoplasma pneumoniae; and Streptococcus pneumoniae in children were collected from the National Infectious Disease Register over the period of 2017–2020. Weekly incidences (weeks 1 to 35) with 95% confidence intervals (CIs) were calculated per 100 000 children in 2020 and compared by incidence rate ratios (IRRs) to corresponding periods in 2017−2019. Findings: The lockdown had immediate impact on the incidences of respiratory pathogens except SARS-CoV-2. Week after the lockdown began IRR was 0•3 (CI 0•3–0•4) and next week the IRR was 0•1 (0•1–0•2). The incidence of SARS-CoV-2 started to decline eight weeks after the lockdown began. The highest recorded weekly incidence of SARS-CoV-2 was 7•2/100 000 children. The effect of the lockdown lasted until late summer. Rhinovirus and SARS-CoV-2 began to increase before the schools or day cares opened in August. The re-opening of schools seemed to have no impact on the incidence of any pathogen. Interpretation: Our results suggest that general social distancing, including school and day care closures, played a crucial role in reducing infections, and the effect lasted for several weeks. The re-opening of schools and day care centres seems to have had no immediate impact on the incidences of any respiratory pathogens. Funding: This study had no funding source.publishedVersionPeer reviewe

Statin Use and Breast Cancer Survival : A Nationwide Cohort Study from Finland

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