392 research outputs found

    Ising nematic phase in ultra-thin magnetic films: a Monte Carlo study

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    We study the critical properties of a two--dimensional Ising model with competing ferromagnetic exchange and dipolar interactions, which models an ultra-thin magnetic film with high out--of--plane anisotropy in the monolayer limit. We present numerical evidence showing that two different scenarios appear in the model for different values of the exchange to dipolar intensities ratio, namely, a single first order stripe - tetragonal phase transition or two phase transitions at different temperatures with an intermediate Ising nematic phase between the stripe and the tetragonal ones. Our results are very similar to those predicted by Abanov et al [Phys. Rev. B 51, 1023 (1995)], but suggest a much more complex critical behavior than the predicted by those authors for both the stripe-nematic and the nematic-tetragonal phase transitions. We also show that the presence of diverging free energy barriers at the stripe-nematic transition makes possible to obtain by slow cooling a metastable supercooled nematic state down to temperatures well below the transition one.Comment: 13 pages, 19 figure

    Interplay between coarsening and nucleation in an Ising model with dipolar interactions

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    We study the dynamical behavior of a square lattice Ising model with exchange and dipolar interactions by means of Monte Carlo simulations. After a sudden quench to low temperatures we find that the system may undergo a coarsening process where stripe phases with different orientations compete or alternatively it can relax initially to a metastable nematic phase and then decay to the equilibrium stripe phase through nucleation. We measure the distribution of equilibration times for both processes and compute their relative probability of occurrence as a function of temperature and system size. This peculiar relaxation mechanism is due to the strong metastability of the nematic phase, which goes deep in the low temperature stripe phase. We also measure quasi-equilibrium autocorrelations in a wide range of temperatures. They show a distinct decay to a plateau that we identify as due to a finite fraction of frozen spins in the nematic phase. We find indications that the plateau is a finite size effect. Relaxation times as a function of temperature in the metastable region show super-Arrhenius behavior, suggesting a possible glassy behavior of the system at low temperatures

    Left Ventricular Ejection Fraction in Patients With Ovarian Cancer Treated With Avelumab, Pegylated Liposomal Doxorubicin, or Both

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    In the phase III JAVELIN Ovarian 200 trial, 566 patients with platinum-resistant/refractory ovarian cancer were randomized 1:1:1 to receive avelumab alone, avelumab plus pegylated liposomal doxorubicin (PLD), or PLD alone. Cardiac monitoring was included for all patients. We report left ventricular ejection fraction (LVEF) data from the trial. Grade ≥3 cardiac adverse events (AEs) occurred in 4 (2.1%), 1 (0.5%), and 0 patients in the avelumab, combination, and PLD arms, respectively. LVEF decreases of ≥10% to below institutional lower limit of normal at any time during treatment were observed in 1 (0.8%), 3 (1.9%), and 2 (1.5%) patients, respectively; 4 had subsequent assessments, and these showed transient decreases. No patient had a cardiovascular AE related to LVEF decrease. This analysis is, to our knowledge, the first analysis of LVEF in patients receiving immune checkpoint inhibitors. CLINICALTRIALS.GOV IDENTIFIER: NCT02580058

    RELAÇÃO ENTRE O ESTILO DE VIDA E O PERFIL ANTROPOMÉTRICO DOS ALUNOS DO ENSINO MÉDIO INTEGRADO EM INFORMÁTICA DO IF-SC CAMPUS CHAPECÓ

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    O presente trabalho visa apresentar resultados sobre o estilo de vida dos alunos do Ensino Médio Integrado em Informática (EMI)-IFSC, do Campus Chapecó. O estilo de vida determina em grande parte a expectativa de vida e qualidade com que se vive,e também é uma estratégia para promoção da saúde e conquista do bem-estar

    Strategies for improved yield and water use efficiency of lettuce (Lactuca sativa L.) through simplified soilless cultivation under semi-arid climate

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    Simplified soilless cultivation (SSC) systems have globally spread as growing solutions for low fertility soil regions, low availability of water irrigation, small areas and polluted environments. In the present study, four independent experiments were conducted for assessing the applicability of SSC in the northeast of Brazil (NE-Brazil) and the central dry zone of Myanmar (CDZ-Myanmar). In the first two experiments, the potentiality for lettuce crop production and water use efficiency (WUE) in an SSC system compared to traditional on-soil cultivation was addressed. Then, the definition of how main crop features (cultivar, nutrient solution concentration, system orientation and crop position) within the SSC system affect productivity was evidenced. The adoption of SSC improved yield (+35% and +72%, in NE-Brazil and CDZ-Myanmar) and WUE (7.7 and 2.7 times higher, in NE-Brazil and CDZ-Myanmar) as compared to traditional on-soil cultivation. In NE-Brazil, an eastern orientation of the system enabled achievement of higher yield for some selected lettuce cultivars. Furthermore, in both the considered contexts, a lower concentration of the nutrient solution (1.2 vs. 1.8 dS m−1) and an upper plant position within the SSC system enabled achievement of higher yield and WUE. The experiments validate the applicability of SSC technologies for lettuce cultivation in tropical areas

    A computational study of the configurational and vibrational contributions to the thermodynamics of substitutional alloys: the Ni3Al case

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    We have developed a methodology to study the thermodynamics of order-disorder transformations in n-component substitutional alloys that combines nonequilibrium methods, which can efficiently compute free energies, with Monte Carlo simulations, in which configurational and vibrational degrees of freedom are simultaneously considered on an equal footing basis. Furthermore, by appropriately constraining the system, we were able to compute the contributions to the vibrational entropy due to bond proportion, atomic size mismatch, and bulk volume effects. We have applied this methodology to calculate configurational and vibrational contributions to the entropy of the Ni3Al alloy as functions of temperature. We found that the bond proportion effect reduces the vibrational entropy at the order-disorder transition, while the size mismatch and the bond proportion effects combined do not change the vibrational entropy at the transition. We also found that the volume increase at the order-disorder transition causes a vibrational entropy increase of 0.08 kB/atom, which is significant when compared to the configurational entropy increase of 0.27 kB/atom. Our calculations indicate that the inclusion of vibrations reduces in about 30 percent the order-disorder transition temperature determined solely considering the configurational degrees of freedom.Comment: Already submitte
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