VARIABILITY, HERITABILITY AND CORRELATIONS OF EGG SHAPE IN THE ZATORSKA GOOSE

The experiment was aimed at the evaluation of inheritance of goose egg measurements, egg shape indices and egg weight as well as the relationship between these traits. The research was carried out in the flock of the Zatorska geese, belonging to the FAO registered genetic resources of poultry. Seven hundred sixty-one eggs from pedigree bred geese in their first to fourth reproduction seasons were included in the analysis. Average egg shape index was 68.8%, average shell surface area was 140.6 cm2. Egg weight of geese in different age was 165 g. Heritabilities and genetic and phenotypic correlations estimated between the analysed traits of goose egg are presented

Development of database application for computer glossary

Katedra informačních technologií a technické výchovyPedagogická fakultaFaculty of Educatio

Effect of corrosion environment on the long-term stability of composite material to enamel and dentin bonds

Souhrn Úvod: Implementace adhezivních technologií do terapie zubního kazu přinesla rozpoznatelný pokrok do stomatologické praxe, projevující se nejen vysoce estetickým výsledkem ošetření, ale také možností ušetřit velký objem tvrdých zubních tkání, k jejichž ztrátám vedly dřívější výplňové technologie s invazivní preparací kazivých lézí pro dosažení mechanické retence výplňových materiálů. Včasné zastavení progrese zubního kazu pomocí adhezivních technologií vytvořilo předpoklady pro výraznější preventivní účinek ošetření zubního kazu, akcelerovaný neustále pokračujícím vývojem adhezivních prostředků a kompozitních materiálů, zajišťujících akceptovatelně dlouhou životnost z nich zhotovených rekonstrukcí. Adhezní spoje dentálních rekonstrukcí jsou v ústní dutině vystaveny různým mechanickým, chemickým a biologickým vlivům. Jedním z významných chemických agens jsou peroxidové bělicí gely, používané pro zesvětlení zubů. Tento kosmetický výkon je dnes ve stomatologické praxi velmi rozšířen. Účinnou látkou bělicích gelů je peroxid vodíku či jeho prekurzory, které při svém rozkladu uvolňují kyslíkové radikály, reagující s chromorforními molekulami pigmentů, usazených v tvrdých zubních tkáních. Volné radikály však reagují nespecificky, tj. nejenom s chromoforními molekulami, ale i s tvrdými zubními tkáněmi,...Introduction: Adhesive technology represents a significant advancement among different treatment options of dental caries. Its advantages involve not only highly aesthetic reconstructions, but also ability to preserve hard dental tissues compared to more traditional filling materials such as amalgam, where the material retention was achieved through undercuts. A potential of adhesive technology to arrest progression of an incipient caries has triggered its wider use in dental caries management, potentiated by an ongoing development of new adhesive systems and composite materials that assure an acceptable long-term stability of adhesive reconstructions. Adhesive bonds of dental reconstructions are in the oral cavity constantly challenged by various mechanical, chemical and biological factors. One of the chemical agents with detrimental potential is peroxide bleaching gel used for teeth brightening. Currently bleaching belongs to the most frequent cosmetic dental procedures. The active ingredient of bleaching gels is hydrogen peroxide or its precursors. It is assumed that free oxygen radicals released from peroxides attack double bonds of chromophore molecules captured within the tooth tissues. Because of the high reactivity and nonspecific nature of these oxygen radicals, they may affect also dental...Institute for Clinical and Experimental Stomatology First Faculty of Medicine Charles UniversityÚstav klinické a experimentální stomatologie 1. LF UK a VFN v PrazeFirst Faculty of Medicine1. lékařská fakult

Effect of chemical composition and temperature on viscosity and structure of molten CaO-Al2O3-SiO2 system

The effects of the change of chemical composition and temperature on the viscosity of CaO-Al2O3-SiO2 oxide system with basicity from 0.78 to 1.63 were investigated in this paper. Experimental measurements of viscosity were performed with use of the high-temperature viscometer Anton Paar FRS 1600. Viscosity was measured in a rotational mode during heating at the rate of 2.2 K/min in the temperature interval from 1673 to 1873 K. Viscosity is often sensitive to the structural changes in molten oxide systems, which implies that the analysis of viscosity is an effective way to understand the structure of molten oxide systems. Exact clarification of the change of structure of the oxide system caused by increased content of CaO was performed by Fourier transform infrared spectroscopy (FTIR), Raman spectroscopy and X-ray diffraction (XRD).Web of Science6042878287

Diagnosis and treatment of renal artery stenosis — review of the literature

Zwężenie tętnic nerkowych (RAS) występuje u 6–8% osób po 65. roku życia. Skutkami zwężenia są zwiększenie częstości występowania incydentów sercowo-naczyniowych oraz wyższa śmiertelność pacjentów. Ciągły rozwój metod diagnostycznych ułatwia wykrycie tej patologii oraz umożliwia jej dokładny opis. Sposób leczenia RAS oraz jego skutków wciąż nie został jednoznacznie ustalony. Opublikowane dotychczas wyniki badań dowiodły wyższość leczenia farmakologicznego nad postępowaniem zabiegowym, jednak wskazano na licznenie dopatrzenia w sposobie ich przeprowadzenia.Skutkowało to rozpoczęciem kolejnych badań, których wyniki jeszcze nie są znane. Celem tej pracy jest przedstawienie aktualnych sposobów diagnostyki i leczenia RAS oraz opis przeprowadzonych dotychczas badań, w których porównywano różne strategie leczenia.Renal artery stenosis (RAS) is encountered in about 6–8% of people older than 65 years. This pathology leads to the higher rate of cardiovascular events as well as higher mortality. Constant progress inimaging techniques allows greater accuracy and sensitivity during diagnosis of RAS. Nevertheless, the way of treating patients with RAS is not clear. Medical treatment is better than renal artery revascularization according to currently published trials. However, some serious mistakes were reported in their methodology. There are a few trials going on but results are still not known. The goal of this review is to present up-to-date methods of diagnosis and treatment of RAS as well as to present published trials comparing alternative methods of treatment

Comparison of the Physicochemical Properties of Carboxylic and Phosphonic Acid Self-Assembled Monolayers Created on a Ti-6Al-4V Substrate

This study compared the tribological properties in nano- and millinewton load ranges of Ti-6Al-4V surfaces that were modified using self-assembled monolayers (SAMs) of carboxylic and phosphonic acids. The effectiveness of the creation of SAMs with the use of the liquid phase deposition (LPD) technique was monitored by the contact angle measurement, the surface free energy (SFE) calculation, X-ray photoelectron spectroscopy (XPS), and Fourier-transform infrared spectroscopy (FTIR) measurements. The obtained results indicated that more stable and well-ordered layers, which were characterized by the lowest values of the coefficient of friction, adhesion, and wear rate, were obtained using phosphonic acid as a surface modifier. Based on the obtained results, it was found that the Ti-6Al-4V alloy modified by phosphonic acid would be the most advantageous for practical applications, especially in micro- and nanoelectromechanical systems (MEMS/NEMS)

The biological rhythms interview of assessment in neuropsychiatry in patients with bipolar disorder : correlation with affective temperaments and schizotypy

Objective: To assess the relationship of biological rhythms, evaluated by the Biological Rhythms Interview of Assessment in Neuropsychiatry (BRIAN), with affective temperaments and schizotypy. Methods: The BRIAN assessment, along with the Temperament Evaluation of Memphis, Pisa, Paris, and San Diego-Autoquestionnaire (TEMPS-A) and the Oxford-Liverpool Inventory for Feelings and Experiences (O-LIFE), was administered to 54 patients with remitted bipolar disorder (BD) and 54 healthy control (HC) subjects. Results: The TEMPS-A cyclothymic temperament correlated positively and the hyperthymic temperament correlated negatively with BRIAN scores in both the BD and HC groups, although the correlation was stronger in BD subjects. Depressive temperament was associated with BRIAN scores in BD but not in HC; conversely, the irritable temperament was associated with BRIAN scores in HC, but not in BD. Several positive correlations between BRIAN scores and the schizotypal dimensions of the O-LIFE were observed in both BD and HC subjects, especially with cognitive disorganization and less so with unusual experiences and impulsive nonconformity. A correlation with introversion/anhedonia was found only in BD subjects. Conclusion: Cyclothymic and depressive temperaments predispose to disturbances of biological rhythms in BD, while a hyperthymic temperament can be protective. Similar predispositions were also found for all schizotypal dimensions, mostly for cognitive disorganization

The intervertebral disc contains intrinsic circadian clocks that are regulated by age and cytokines and linked to degeneration

ObjectivesThe circadian clocks are internal timing mechanisms that drive ∼24-hour rhythms in a tissue-specific manner. Many aspects of the physiology of the intervertebral disc (IVD) show clear diurnal rhythms. However, it is unknown whether IVD tissue contains functional circadian clocks and if so, how their dysregulation is implicated in IVD degeneration.MethodsClock gene dynamics in ex vivo IVD explants (from PER2:: luciferase (LUC) reporter mice) and human disc cells (transduced with lentivirus containingPer2::luc reporters) were monitored in real time by bioluminescence photon counting and imaging. Temporal gene expression changes were studied by RNAseq and quantitative reverse transcription (qRT)-PCR. IVD pathology was evaluated by histology in a mouse model with tissue-specific deletion of the core clock geneBmal1.ResultsHere we show the existence of the circadian rhythm in mouse IVD tissue and human disc cells. This rhythm is dampened with ageing in mice and can be abolished by treatment with interleukin-1β but not tumour necrosis factor α. Time-series RNAseq revealed 607 genes with 24-hour patterns of expression representing several essential pathways in IVD physiology. Mice with conditional knockout ofBmal1in their disc cells demonstrated age-related degeneration of IVDs.ConclusionsWe have established autonomous circadian clocks in mouse and human IVD cells which respond to age and cytokines, and control key pathways involved in the homeostasis of IVDs. Genetic disruption to the mouse IVD molecular clock predisposes to IVD degeneration. These results support the concept that disruptions to circadian rhythms may be a risk factor for degenerative IVD disease and low back pain.</jats:sec