3,644 research outputs found

    Does screening reduce lung cancer mortality?

    Get PDF
    Neither routine chest x-ray (with or without sputum cytology) nor low-dose computed tomography (CT) have been proven to reduce mortality when used for lung cancer screening, although low-dose CT screening does identify lung cancer at an early stage in high-risk patients (strength of recommendation: B, based on heterogeneous cohort studies). Large studies of both imaging approaches are ongoing

    Multi-Scale Entropy Analysis as a Method for Time-Series Analysis of Climate Data

    Get PDF
    Evidence is mounting that the temporal dynamics of the climate system are changing at the same time as the average global temperature is increasing due to multiple climate forcings. A large number of extreme weather events such as prolonged cold spells, heatwaves, droughts and floods have been recorded around the world in the past 10 years. Such changes in the temporal scaling behaviour of climate time-series data can be difficult to detect. While there are easy and direct ways of analysing climate data by calculating the means and variances for different levels of temporal aggregation, these methods can miss more subtle changes in their dynamics. This paper describes multi-scale entropy (MSE) analysis as a tool to study climate time-series data and to identify temporal scales of variability and their change over time in climate time-series. MSE estimates the sample entropy of the time-series after coarse-graining at different temporal scales. An application of MSE to Central European, variance-adjusted, mean monthly air temperature anomalies (CRUTEM4v) is provided. The results show that the temporal scales of the current climate (1960–2014) are different from the long-term average (1850–1960). For temporal scale factors longer than 12 months, the sample entropy increased markedly compared to the long-term record. Such an increase can be explained by systems theory with greater complexity in the regional temperature data. From 1961 the patterns of monthly air temperatures are less regular at time-scales greater than 12 months than in the earlier time period. This finding suggests that, at these inter-annual time scales, the temperature variability has become less predictable than in the past. It is possible that climate system feedbacks are expressed in altered temporal scales of the European temperature time-series data. A comparison with the variance and Shannon entropy shows that MSE analysis can provide additional information on the statistical properties of climate time-series data that can go undetected using traditional method

    Radiative transfer in a spherical, emitting, absorbing and anisotropically scattering medium

    Full text link
    The atmospheres of planets (including Earth) and the outer layers of stars have often been treated in radiative transfer as plane-parallel media, instead of spherical shells, which can lead to inaccuracy, e.g. limb darkening. We give an exact solution of the radiative transfer specific intensity at all points and directions in a finite spherical medium having arbitrary radial spectral distribution of: source (temperature), absorption, emission and anisotropic scattering. The power and efficiency of the method stems from the spherical numerical gridding used to discretize the transfer equations prior to matrix solution: the wanted ray and the rays which scatter into it both have the same physico-geometric structure. Very good agreement is found with an isotropic astrophysical benchmark (Avrett & Loeser, 1984). We introduce a specimen arbitrary forward-back-side phase scattering function for future comparisons. Our method directly and exactly addresses spherical symmetry with anisotropic scattering, and could be used to study the Earth's climate, nuclear power (neutron diffusion) and the astrophysics of stars and planets.Comment: 8 pages, 2 figures, spherical radiative transfer: stellar, planetary, terrestia

    Reproductive health education in the schools of the four UK nations: is it falling through the gap?

    Get PDF
    Reproductive health education is crucial to ensure young people understand their reproductive system and can make informed decisions about their sexual lives and fertility, including whether they want to have children or not. This study involved an investigation of the intended UK school curricula for 14-18 year-olds as they relate to reproductive health. Analysis revealed substantial differences. Most, but not all, specifications include sexually transmitted infections, hormonal aspects of reproduction, contraception, the menstrual cycle and assisted reproductive technology (ART). Important topics, such as endometriosis, fertility, preconception health, pregnancy, miscarriage, menopause and infertility (except in the context of ART) are missing from examination specifications and/or the RSE/RSHP curricula. We conclude that many young people in the UK are at risk of leaving school with inadequate understanding of concepts that have important implications for their reproductive health. There are differences between nations, with Scotland having the most comprehensive coverage of topics in its curriculum. High-quality reproductive health education should be an entitlement for all young people. It should give young people accurate and up-to-date information and enable them to discuss issues and develop their own thinking. Ideally, sex and reproductive health education would be taught comprehensively across the RSE/RSHP and science curricula

    Sex and fertility education in England: an analysis of biology curricula and students’ experiences

    Get PDF
    Sex and fertility education is essential to enable people to make informed choices. School is an important source of education, so we examined the current curriculum relating to sex and fertility education in England and compared it with students’ accounts of their experiences. We analysed the Awarding Body GCSE science and biology specifications (for 14–16 year-olds) and the A-level biology specifications (for 16–18 year-olds), as these related to relationships, sexuality and fertility. An online survey was conducted with 221 16–17 year-old school students to evaluate their views about their sex and fertility education. We found significant variation between the specifications of the Awarding Bodies at both GCSE and A level. Most of the specifications specify sexually transmitted infections (STIs), hormonal aspects of reproduction and contraception. In the school survey, students indicated that topics such as puberty, contraception and STIs were more likely to be learnt in school. However, topics such as endometriosis, menopause and miscarriage were more likely to be learnt outside school. From both our curriculum analysis and student survey we conclude that there are significant gaps in the curriculum with many important topics being neglected
    corecore