1,778 research outputs found
The Four-Loop Planar Amplitude and Cusp Anomalous Dimension in Maximally Supersymmetric Yang-Mills Theory
We present an expression for the leading-color (planar) four-loop four-point
amplitude of N=4 supersymmetric Yang-Mills theory in 4-2 e dimensions, in terms
of eight separate integrals. The expression is based on consistency of
unitarity cuts and infrared divergences. We expand the integrals around e=0,
and obtain analytic expressions for the poles from 1/e^8 through 1/e^4. We give
numerical results for the coefficients of the 1/e^3 and 1/e^2 poles. These
results all match the known exponentiated structure of the infrared
divergences, at four separate kinematic points. The value of the 1/e^2
coefficient allows us to test a conjecture of Eden and Staudacher for the
four-loop cusp (soft) anomalous dimension. We find that the conjecture is
incorrect, although our numerical results suggest that a simple modification of
the expression, flipping the sign of the term containing zeta_3^2, may yield
the correct answer. Our numerical value can be used, in a scheme proposed by
Kotikov, Lipatov and Velizhanin, to estimate the two constants in the
strong-coupling expansion of the cusp anomalous dimension that are known from
string theory. The estimate works to 2.6% and 5% accuracy, providing
non-trivial evidence in support of the AdS/CFT correspondence. We also use the
known constants in the strong-coupling expansion as additional input to provide
approximations to the cusp anomalous dimension which should be accurate to
under one percent for all values of the coupling. When the evaluations of the
integrals are completed through the finite terms, it will be possible to test
the iterative, exponentiated structure of the finite terms in the four-loop
four-point amplitude, which was uncovered earlier at two and three loops.Comment: 72 pages, 15 figures, v2 minor correction
PATHOGENESIS OF CHRONIC DISEASE ASSOCIATED WITH PERSISTENT LYMPHOCYTIC CHORIOMENINGITIS VIRAL INFECTION : II. RELATIONSHIP OF THE ANTI-LYMPHOCYTIC CHORIOMENINGITIS IMMUNE RESPONSE TO TISSUE INJURY IN CHRONIC LYMPHOCYTIC CHORIOMENINGITIS DISEASE
Tissue injury (chronic disease) associated with persistent LCM infection is apparently caused by the host immune response to the virus. Employing parabiosis or cell transfer from hyperimmune donors to isologous virus carriers, the tissue injury of chronic disease could be initiated and/or intensified. Furthermore, the transfer of anti-LCM antibody to SWR/J carrier mice results in acute necrotizing inflammatory lesions in regions of viral persistence, followed by chronic mononuclear infiltrates quite similar to those seen after the transfer of immune cells. The pathogenesis of the nonglomerular tissue injury of chronic LCM disease is apparently at least in part related to the interaction of circulating anti-LCM antibody with viral antigen at the tissue site. Trapping of circulating virus-antibody complexes in the glomerular filter is apparently the major cause of the glomerulonephritis
PATHOGENESIS OF CHRONIC DISEASE ASSOCIATED WITH PERSISTENT LYMPHOCYTIC CHORIOMENINGITIS VIRAL INFECTION : I. RELATIONSHIP OF ANTIBODY PRODUCTION TO DISEASE IN NEONATALLY INFECTED MICE
Mice infected shortly after birth with lymphocytic choriomeningitis (LCM) virus are not immunologically tolerant, although they carry the virus throughout life. These LCM carrier mice make anti-LCM antibody, which apparently complexes with viral antigen in the circulation and these complexes accumulate in the glomeruli. LCM carrier mice of different strains vary significantly as to concentration of detectable infectious virus in their tissue, amount and time of appearance of anti-LCM antibody, and development of an associated chronic disease. The chronic disease consists primarily of glomerulonephritis, focal hepatic necrosis, and disseminated lymphoid infiltrations. LCM carriers of the SWR/J strain contain high tissue concentrations of virus, considerable anti-LCM antibody detectable in the glomeruli by 3 wk to 2 months of age and develop chronic disease within the first 2â3 months of life. In contrast, C3H strain LCM carriers contain 1/1000 as much infectious virus, less detectable anti-LCM antibody, and have not, over a 24 month observation period, developed any detectable disease. B10D2 old and new carrier mice with intermediate amounts of virus develop chronic disease during the latter half of the first year of life. The pathogenesis of the glomerulonephritis of chronic LCM disease is apparently related to the formation of circulating virus-antibody complexes which are trapped in the glomerular filter. There is no evidence for direct glomerular injury by the virus nor for any autoimmune response by the host
DISEASE ACCOMPANYING IN UTERO VIRAL INFECTION : THE ROLE OF MATERNAL ANTIBODY IN TISSUE INJURY AFTER TRANSPLACENTAL INFECTION WITH LYMPHOCYTIC CHORIOMENINGITIS VIRUS
Early, after in utero infection with LCM virus, SWR/J and HA/ICR mice developed manifestations of immune complex disease. Observations based on nursing such mice with virus-infected, immune, or noninfected mouse mothers indicated that maternal antiviral antibody was responsible for the early immune complex glomerulonephritis. Despite comparable viral persistance, in utero-infected offspring failed to develop glomerulonephritis when nursed by noninfected mouse mothers, but did when suckled by virus-infected mouse mothers. Nursing by mouse mothers carrying high titers of anti-LCM viral antibody markedly enhanced the Ig glomerular deposits and the resultant nephritis
Antitakeover Provisions and CEO Monetary Benefits: Revisiting the E-Index
We analyze and group antitakeover provisions as they relate to CEOâs monetary benefits. We specifically focus on the determinants of the six E-index provisions that were proposed by Bebchuk et al. (2009) to conversely affect firm value. The six provisions are split into two indices: those that provide managers with a monetary benefit if a takeover was successful (MB provisions) and those that do not (TP provisions). Results indicate that CEOs with a role duality use their power to influence the adoption of MB provisions and resist the adoption of TP provisions. Moreover, in the presence of CEO duality, the relationship between MB provisions and firm value worsens. On the other hand, the relationship between TP provisions and firm value is unaffected by the presence of CEO duality. This suggests that CEOs having a role duality do not feel the need to work in the shareholdersâ best interest when entrenched with MB provisions. Our findings suggest that studying all the provisions of the E-index as a whole can be misleading in some cases
Sport and Family Functioning: Strengthening Elite Sport Families
Families play an important role in society, both in human sustenance and individual development. Family systems theory views the family as a series of interconnected parts that when functioning properly, provide individual members with multiple benefits. Interaction with external systems, such as sport, school or church, can have positive and negative impacts on the family. It is unclear, however, what elements of sport relate to specific outcomes. The purpose of this study is to better understand the relationship between elite youth sport participation and family units, and how these two spheres, individually and in combination, impact family functioning. In-depth, purposeful interviews with seven âsport familiesâ revealed that in addition to the depletion of resources (financial and time), elite sport engagement strongly detracts from the marital dyad and family unit receiving sufficient time and attention for proper functioning.  The results also offer insight into how the leagues can be better managed such that they positively contribute to family functioning.  Specifically, the results indicate that leagues can aid in strengthening family functioning through allowing families to have coaching input, and providing greater attention to scheduling, league expectations, and instrumental support
The Ecological Significance of Emerging Deltas in Regulated Rivers
Sedimentary deltas forming in the worldâs regulated rivers are a glaring gap in our knowledge of dammed riverine ecosystems. Basic ecological information is needed to inform the current debate about whether deltas should be retained and managed to gain ecosystem services lost under reservoirs or whether they should be partially removed to improve flow conveyance and to resupply sediment-starved reaches below dams. An examination of nine deltas on the heavily regulated upper and middle Missouri River showed the following: The sizes, dynamics, and biotic communities vary widely across deltas; riparian forest has established on portions of most deltas; the current delta area is over 1000 square kilometers, exceeding forest area in remnant unimpounded reaches and offering considerable land area for restoration actions; and small adjustments to reservoir operations could improve the restoration potential of deltas. Ecological studies are urgently needed to determine the future role that deltas could play in river ecosystem restoration
Updating Action Descriptions and Plans for Cognitive Agents
Extended Abstract and Poster PresentationPostprin
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