470 research outputs found
Rule Managed Reporting in Energy Controlled Wireless Sensor Networks
This paper proposes a technique to extend the network lifetime of a wireless sensor network, whereby each sensor node decides its network involvement, based on energy resources and the information in each message (ascertained through a system of rules). Results obtained from the simulation of an industrial monitoring scenario have shown that a considerable increase in the lifetime and connectivity can be obtained
Human papillomavirus infection in esophageal squamous cell carcinoma and esophageal adenocarcinoma: a concise review
The causal link between high-risk human papillomavirus (hr-HPV) infection and cervical, anogenital, and some oropharyngeal malignancies has been established by both molecular and epidemiological data. The association between HPV and esophageal squamous cell carcinoma (ESCC) remains controversial, as is the true prevalence of HPV infection in ESCC. The wide range in reported rates reflects variability in the primary literature, with some larger scale case–control studies suggesting the infection rates range from 0% to 78%. Interactions between HPV and the Barrett's metaplasia–dysplasia–carcinoma sequence have been explored, and these studies have shown some conflicting data. Overall, systematic reviews have reported the prevalence of HPV-positive DNA in esophageal adenocarcinoma patients of between 13% and 35%. Postulated reasons for discrepancies in HPV prevalence rates in esophageal cancer include variations in testing methodology and assay sensitivities; technical issues, including the lack of a gold-standard primer; types of specimens utilized (fresh-frozen versus formalin-fixed tissue); geographical variation; cross-contamination; and small sample sizes. Thus, efforts must be undertaken to (1) standardize HPV testing, ideally in a central laboratory and utilizing tests that detect viral transcriptional activity; (2) avoid cross-contamination; and (3) recruit large numbers of patients to accurately ascertain HPV rates in esophageal malignancy
Pancreatectomy is underused in NSW regions with low institutional surgical volumes: A population data linkage study
© 2017 AMPCo Pty Ltd. Produced with Elsevier B.V. All rights reserved. Objective: To examine differences in the proportions of people diagnosed with pancreatic cancer who underwent pancreatectomy, post-operative outcomes and 5-year survival in different New South Wales administrative health regions of residence. Design, setting and participants: Retrospective analysis of NSW data on pancreatic cancer incidence and surgery, 2005e2013. Main outcome measures: The proportion of newly diagnosed patients with pancreatic cancer who were resected in each region; 90-day post-operative mortality; one-year post-operative survival; 5-year post-diagnosis survival. Results: 14% of people diagnosed with pancreatic cancer during 2010e2013 (431 of 3064) underwent pancreatectomy, an average of 108 resections per year. After adjusting for age, sex and comorbidities, the proportion that underwent resection varied significantly between regions, ranging between 8% and 21% (P<0.001). Higher resection rates were not associated with higher post-operative 90-day mortality or lower one-year survival (unadjusted and risk-adjusted analyses). Higher resection rates were associated with higher 5-year post-diagnosis survival: the mean survival in regions with resection rates below 10% was 3.4%, compared with 7.2% in regions with rates greater than 15% (unadjusted and adjusted survival analyses; P<0.001). There was a positive association between regional resection rate and the pancreatectomy volume of hospitals during 2005e2009. An additional 32 people would be resected annually if resection rates in low rate regions were increased to the 80th percentile regional resection rate (18%). Conclusion: There is significant geographic variation in the proportion of people with pancreatic cancer undergoing pancreatectomy, and the 5-year survival rate is higher in regions where this proportion is higher
Oxidative phosphorylation during glycollate metabolism in mitochondria from phototrophic Euglena gracilis
Mapping the Stellar Dynamics of M31
Using the Planetary Nebula Spectrograph, we have observed and measured the
velocities for some 2764 PNe in the disk and halo of the Andromeda galaxy.
Preliminary analysis using a basic ring model shows a rotation curve in good
agreement with that obtained from HI data out to ~20kpc. Some substructure has
also been detected within the velocity field, which can be modeled as the
continuation of the tidal-remnant known as the Southern Stream, as it passes
through Andromeda's disk.Comment: 5 pages, 3 figures, to appear in the proceedings of the ESO-Workshop
"Planetary Nebulae beyond the Milky Way", May 19 - 21 (2004), ed. J. R.
Walsh, L. Stanghellini, Springer-Verla
Augmenting forearm crutches with wireless sensors for lower limb rehabilitation
Forearm crutches are frequently used in the rehabilitation of an injury to the lower limb. The recovery rate is improved if the patient correctly applies a certain fraction of their body weight (specified by a clinician) through the axis of the crutch, referred to as partial weight bearing (PWB). Incorrect weight bearing has been shown to result in an extended recovery period or even cause further damage to the limb. There is currently no minimally invasive tool for long-term monitoring of a patient's PWB in a home environment. This paper describes the research and development of an instrumented forearm crutch that has been developed to wirelessly and autonomously monitor a patient's weight bearing over the full period of their recovery, including its potential use in a home environment. A pair of standard forearm crutches are augmented with low-cost off-the-shelf wireless sensor nodes and electronic components to provide indicative measurements of the applied weight, crutch tilt and hand position on the grip. Data are wirelessly transmitted between crutches and to a remote computer (where they are processed and visualized in LabVIEW), and the patient receives biofeedback by means of an audible signal when they put too much or too little weight through the crutch. The initial results obtained highlight the capability of the instrumented crutch to support physiotherapists and patients in monitoring usage
Management of acute appendicitis during the COVID-19 pandemic : a retrospective cohort study
Background: The Coronavirus Disease 2019 (COVID-19) pandemic profoundly impacted delivery of health care. South Western Sydney Local Health District (SWSLHD) experienced some of the highest cases, admissions and deaths during the Delta and Omicron waves in New South Wales. This study aims to determine the impact of the pandemic on emergency surgery services for adults presenting with acute appendicitis. Methods: A retrospective review of patient records was performed of adults presenting with acute appendicitis between 1st March 2021 and 31st March 2022, which was compared to a pre-COVID control period of the same dates in 2019–2020. Patients managed operatively or conservatively were included. Results: 1556 patients were included in the operative arm; 723 and 833 respectively in the study and control groups, which were comparable at baseline. 1.66% were COVID positive. During the pandemic, patients were significantly more likely to be investigated with computered tomography (CT) scan (p ≤ 0.001), present with complicated appendicitis (p = 0.03), and require caecectomy (p = 0.005). They had higher American Society of Anaesthesiology (ASA) scores (p = 0.001) and significantly lower negative appendectomy rates (p = 0.001). Fifty-two patients were included in the conservative arm; 29 and 23 respectively in the pandemic and control groups. Patients were comparable at baseline. There were two COVID positive patients. During the pandemic, there was a significant reduction in complications (p = 0.033), readmissions (0.044) and interval appendicectomy (p = 0.0044). Conclusion: We identified higher rates of complicated appendicitis, caecectomies and greater reliance on CT imaging preoperatively during the pandemic in SWSLHD
Unravelling the origins of S0 galaxies using maximum likelihood analysis of planetary nebulae kinematics
To investigate the origins of S0 galaxies, we present a new method of analysing their stellar kinematics from discrete tracers such as planetary nebulae. This method involves binning the data in the radial direction so as to extract the most general possible non-parametric kinematic profiles, and using a maximum-likelihood fit within each bin in order to make full use of the information in the discrete kinematic tracers. Both disc and spheroid kinematic components are fitted, with a two-dimensional decomposition of imaging data used to attribute to each tracer a probability of membership in the separate components. Likelihood clipping also allows us to identify objects whose properties are not consistent with the adopted model, rendering the technique robust against contaminants and able to identify additional kinematic features. The method is first tested on an N-body simulated galaxy to assess possible sources of systematic error associated with the structural and kinematic decomposition, which are found to be small. It is then applied to the S0 system NGC 1023, for which a planetary nebula catalogue has already been released and analysed by Noordermer et al. The correct inclusion of the spheroidal component allows us to show that, contrary to previous claims, the stellar kinematics of this galaxy are indistinguishable from those of a normal spiral galaxy, indicating that it may have evolved directly from such a system via gas stripping or secular evolution. The method also successfully identifies a population of outliers whose kinematics are different from those of the main galaxy; these objects can be identified with a stellar stream associated with the companion galaxy NGC 1023A
Tracing the star stream through M31 using planetary nebula kinematics
We present a possible orbit for the Southern Stream of stars in M31, which connects it to the Northern Spur. Support for this model comes from the dynamics of planetary nebulae (PNe) in the disc of M31: analysis of a new sample of 2611 PNe obtained using the Planetary Nebula Spectrograph reveals ∼20 objects with kinematics inconsistent with the normal components of the galaxy, but which lie at the right positions and velocities to connect the two photometric features via this orbit. The satellite galaxy M32 is coincident with the stream both in position and velocity, adding weight to the hypothesis that the stream comprises its tidal debri
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