Compression methods for XUV attosecond pulses

none5noneMark Mero;Fabio Frassetto;Paolo Villoresi;Luca Poletto;Katalin VarjúMark, Mero; Fabio, Frassetto; Villoresi, Paolo; Luca, Poletto; Katalin, Varj

Choice of sprint start performance measure affects the performance-based ranking within a group of sprinters: which is the most appropriate measure?

Sprint start performance has previously been quantified using several different measures. This study aimed to identify whether different measures could influence the performance-based ranking within a group of 12 sprinters, and if so, to identify the most appropriate measure. None of the 10 performance measures ranked all sprinters in the same order; Spearman's rho correlations between different block phase measures ranged from 0.50 to 0.94, and between block phase measures and those obtained beyond block exit from 0.66 to 0.85. Based on the consideration of what each measure quantifies, normalised average horizontal external power was identified as the most appropriate, incorporating both block velocity and the time spent producing this velocity. The accuracy with which these data could be obtained in an externally valid field setting was assessed against force platform criterion data. For an athlete producing 678 ± 40 W of block power, a carefully set-up manual high-speed video analysis protocol produced systematic and random errors of +5 W and ± 24 W, respectively. Since the choice of performance measure could affect the conclusions drawn from a technique analysis, for example the success of an intervention, it is proposed that external power is used to quantify start performance

Development and evaluation of tailored specific real-time RT-PCR assays for detection of foot-and-mouth disease virus serotypes circulating in East Africa

AbstractRapid, reliable and accurate diagnostic methods provide essential support to programmes that monitor and control foot-and-mouth disease (FMD). While pan-specific molecular tests for FMD virus (FMDV) detection are well established and widely used in endemic and FMD-free countries, current serotyping methods mainly rely either on antigen detection ELISAs or nucleotide sequencing approaches. This report describes the development of a panel of serotype-specific real-time RT-PCR assays (rRT-PCR) tailored to detect FMDV lineages currently circulating in East Africa. These assays target sequences within the VP1-coding region that share high intra-lineage identity, but do not cross-react with FMD viruses from other serotypes that circulate in the region. These serotype-specific assays operate with the same thermal profile as the pan-diagnostic tests making it possible to run them in parallel to produce CT values comparable to the pan-diagnostic test detecting the 3D-coding region. These assays were evaluated alongside the established pan-specific molecular test using field samples and virus isolates collected from Tanzania, Kenya and Ethiopia that had been previously characterised by nucleotide sequencing. Samples (n=71) representing serotype A (topotype AFRICA, lineage G-I), serotype O (topotypes EA-2 and EA-4), serotype SAT 1 (topotype I (NWZ)) and serotype SAT2 (topotype IV) were correctly identified with these rRT-PCR assays. Furthermore, FMDV RNA from samples that did not contain infectious virus could still be serotyped using these assays. These serotype-specific real-time RT-PCR assays can detect and characterise FMDVs currently circulating in East Africa and hence improve disease control in this region

Biomechanical analysis of the penalty-corner drag-flick of elite male and female hockey players

The aim of this study was to analyse the kinematic sequencing in the penalty-corner drag-flicks of elite male and female field hockey players of international calibre. Thirteen participants (one skilled male drag-flicker and six male and six female elite players) participated in the study. An optoelectronic motion analysis system was used to capture the drag-flicks with six cameras, sampling at 250 Hz. Select ground reaction force parameters were obtained from a force platform which registered the last support of the front foot. Twenty trials were captured from each subject. Both player groups showed significantly (p < 0.05) smaller ball velocity at release, peak angular velocity of the pelvis, and negative and positive peak angular velocities of the stick than the skilled subject. Normalised ground reaction forces of the gender groups were also smaller than that of the skilled drag-flicker. By comparing these players we established that the cues of the skill level are a wide stance, a whipping action (rapid back lift) of the stick followed by an explosive sequential movement of the pelvis, upper trunk and stick

Analysis of Sugarcane Ethanol Production for Energy Development: Case Study Ecuador

The global energy issue is crucial for the development of the population and the environmental protection of the planet. The agricultural sector is part of economic, social and environmental development. However, in Ecuador, this sector has internal problems due to the suspension of the bioconversion project (e.g., ethanol production). This study aims to analyse the situation of sugarcane ethanol production in Ecuador and, through information management, to search for development strategies. The methodology includes the following: (i) sugarcane production analysis in Ecuador and ethanol distribution; (ii) policies and legal context concerning renewable energies and biofuels production in Ecuador; (iii) Political, Economic, Social, Technological, Ecological and Legal (PESTEL) as well as Strengths, Weaknesses, Opportunities and Threats (SWOT) analysis of ethanol production, based on the criteria of the experts involved and (iv) strategic guidelines for sustainable sugarcane ethanol development. Ecuador has a potential for sugarcane ethanol production that is currently not fully exploited; that is, the consumption of this resource would reduce energy demand and economic problems in the agricultural sector. Sugarcane ethanol production has generated a direct contribution to the country’s Gross Domestic Product (0.5%) and a contribution to social growth (751,799 people benefited). Ethanol production could increase by 20%, generating new alternatives for biofuel consumption. This progress in Ecuador would strengthen the contribution to the Sustainable Development Goals criteria and benefit the population with new job opportunities (approximately 42,000). Therefore, the production of ethanol from sugarcane, under a legal framework, benefits economic, social and ecological relations.This work had the collaboration of several business associations, such as the Asociación de Productores de Caña de Azúcar del Cantón Milagro (APCAM) and the Asociación de Biocombustibles del Ecuador (APALE). Alejandro Gallardo and Orlando Zambrano participated in APCAM. In APALE, Gustavo Heinert (president) and Carlos León (analyst) participated. In addition, had the collaboration to project of the ESPOL Polytechnic University such as “Registry of geological and mining heritage and its impact on the defence and preservation of geodiversity in Ecuador” with code CIPAT-01-2018

Dietary polyphenols, metabolic syndrome and cardiometabolic risk factors: An observational study based on the DCH-NG subcohort

Background and aims: Polyphenol-rich foods have beneficial properties that may lower cardiometabolic risk. We aimed to prospectively investigate the relationship between intakes of dietary polyphenols, and metabolic syndrome (MetS) and its components, in 676 Danish residents from the MAX study, a subcohort of the Danish Diet, Cancer and Health–Next Generations (DCH-NG) cohort. Methods and results: Dietary data were collected using web-based 24-h dietary recalls over one year (at baseline, and at 6 and 12 months). The Phenol-Explorer database was used to estimate dietary polyphenol intake. Clinical variables were also collected at the same time point. Generalized linear mixed models were used to investigate relationships between polyphenol intake and MetS. Participants had a mean age of 43.9y, a mean total polyphenol intake of 1368 mg/day, and 75 (11.6%) had MetS at baseline. Compared to individuals with MetS in Q1 and after adjusting for age, sex, lifestyle and dietary confounders, those in Q4 – for total polyphenols, flavonoids and phenolic acids–had a 50% [OR (95% CI): 0.50 (0.27, 0.91)], 51% [0.49 (0.26, 0.91)] and 45% [0.55 (0.30, 1.00)] lower odds of MetS, respectively. Higher total polyphenols, flavonoids and phenolic acids intakes as continuous variable were associated with lower risk for elevated systolic blood pressure (SBP) and low high-density lipoprotein cholesterol (HDL-c) (p &lt; 0.05). Conclusions: Total polyphenol, flavonoid and phenolic acid intakes were associated with lower odds of MetS. These intakes were also consistently and significantly associated with a lower risk for higher SBP and lower HDL-c concentrations

Effect of combined uphill-downhill sprint training on kinematics and maximum running speed in experienced sprinters

This study examined the effects of sprint running training on sloping surfaces (3°) in experienced sprinters using selected kinematic variables. Twelve experienced sprinters were randomly allocated to two training groups (combined uphill–downhill and horizontal). Pre- and post-training tests were performed to examine the effects of six weeks of training on maximum running speed, step rate, step length, step time, contact time, braking and propulsive phase of contact time, flight time and selected postural characteristics during a step cycle in the final steps of a 35m sprint test. In the combined uphill–downhill training group, maximum running speed was substantially greater (from 9.08 ± 0.90 m s-1 to 9.51 ± 0.62 m s-1; p <0.05) after training by 4.8%; step rate, contact time, step time and concentric phase was not modified. There were no significant changes in maximal speed or sprint kinematics in the horizontal training group. Overall, the posture characteristics did not change with training. The combined uphill–downhill training method was substantially more effective in improving the maximum running speed in experienced sprinters than a traditional horizontal training method

Plasma metabolomic profiles of plant-based dietary indices reveal potential pathways for metabolic syndrome associations

Background and aims: Plant-based dietary patterns have been associated with improved health outcomes. This study aims to describe the metabolomic fingerprints of plant-based diet indices (PDI) and examine their association with metabolic syndrome (MetS) and its components in a Danish population. Methods: The MAX study comprised 676 participants (55% women, aged 18-67 y) from Copenhagen. Sociodemographic and dietary data were collected using questionnaires and three 24-h dietary recalls over one year (at baseline, and at 6 and 12 months). Mean dietary intakes were computed, as well as overall PDI, healthful (hPDI) and unhealthful (uPDI) scores, according to food groups for each plant-based index. Clinical variables were also collected at the same time points in a health examination that included complete blood tests. MetS was defined according to the International Diabetes Federation criteria. Plasma metabolites were measured using a targeted metabolomics approach. Metabolites associated with PDI were selected using random forest models and their relationships with PDIs and MetS were analyzed using generalized linear mixed models. Results: The mean prevalence of MetS was 10.8%. High, compared to low, hPDI and uPDI scores were associated with a lower and higher odd of MetS, respectively [odds ratio (95%CI); hPDI: 0.56 (0.43–0.74); uPDI: 1.61 (1.26–2.05)]. Out of 411 quantified plasma metabolites, machine-learning metabolomics fingerprinting revealed 13 metabolites, including food and food-related microbial metabolites, like hypaphorine, indolepropionic acid and lignan-derived enterolactones. These metabolites were associated with all PDIs and were inversely correlated with MetS components (p &lt; 0.05). Furthermore, they had an explainable contribution of 12% and 14% for the association between hPDI or uPDI, respectively, and MetS only among participants with overweight/obesity. Conclusions: Metabolites associated with PDIs were inversely associated with MetS and its components, and may partially explain the effects of plant-based diets on cardiometabolic risk factors