Comparison of a 4-Day versus 2-Day Low Fiber Diet Regimen in Barium Tagging CT Colonography in Incomplete Colonoscopy Patients

Our aim was to compare the amount of residual feces, residual fluid, the tagging quality, and patient compliance using 4-day versus 2-day low fiber diet regimen in barium tagging CT colonography in incomplete colonoscopy patients. Methods. A total of 101 patients who underwent CT colonography were assigned to 2-day diet group (n=56) and 4-day diet group (n=45). Fecal tagging was achieved with barium sulphate while bisacodyl and sennoside B were used for bowel preparation. Residual solid stool was divided into two groups measuring <6 mm and ≥6 mm. We graded the residual fluid, tagging quality for solid stool, and fluid per bowel segment. We performed a questionnaire to assess patient compliance. Results. 604 bowel segments were evaluated. There was no significant difference between 2-day and 4-day diet groups with respect to residual solid stool, residual fluid, tagging quality for stool, and fluid observed in fecal tag CT colonography (P>0.05). The prevalence of moderate discomfort was significantly higher in 4-day group (P<0.001). Conclusion. Our study shows that 2-day limited bowel preparation regimen for fecal tag CT colonography is a safe and reasonable technique to evaluate the entire colon, particularly in incomplete conventional colonoscopy patients

Nosies obstrukcijos kilmės ir operacijų efektyvumo analizė Dicle universiteto (Turkija) LOR klinikos pacientų tarpe

Aim: In this study, the aim was to evaluate the operations for the patients who applied with the etiology of nasal obstruction. Materiel and method: In this study, 260 patients (175 men, 85 women) who applied to the otorhinolaryngology department of the Dicle University medicine faculty with nasal obstruction etiology, the operations, etiology, technique and complications were evaluated between December 2004 and December 2005. 164 of our cases we used general anesthesia and 96 of them were local. Results: The mean age of our patients operated in our clinic was 19.8±12.6 years and the most diagnosis seems to be deviation of septi nasi (DSN) (n=56, 21,5 %); second nasal deformity (n=51,19,6 %) third was chronic adenotonsillitis (n=43, 16,5 %), (p<0.0001). Our cases were mostly between 5-10 and 18-25 years old (155 cases, 57,4 %), (p<0.0001). 69 (24,5 %) cases were between the ages of 5-10, and in these, the most prevalent diseases were with 41 cases of chronic adenotonsillitis and with 17 cases of chronic adenotonsillitis + serous otitis media. 86 (32,9 %) cases were between the ages of 18-25 and in these, the most prevalent diseases were with 31 cases were DSN and nasal deformity for each. In general evaluating the operations we did, the most operation we did were submucosal resection (SMR) (56 cases, 21,5 %), septorhinoplasty (51 cases, 19,6 %) and chronic adenotonsillectomies (43 cases, 16,5 %), (p<0.0001). The complications were unilateral mucosal rupture (12 cases, 4,6 %), bilateral mucosal rupture (2 cases,0.8 %) and post-op hemorrhage (6 cases, 2,3 %) (p=0.022). Conclusion: The patients applied to our clinic seem to be mostly because of DSN and nasal deformity. Especially between the ages of 5-10 chronic adenotonsillitis frequency and between the ages of 18-25 DSN and nasal deformity frequency seems to be increased. Key words: Nasal obstruction, deviation of septi nasi, chronic adenotonsillitis

Symptomatic Bilateral Xanthogranuloma of the Choroid Plexus

Xanthogranulomas (XGRs) of the choroid plexus are rare, asymptomatic, and benign lesions usually found incidentally. Here, we present a case of a 47-year-old male with bilateral XGR of the choroid plexus with periventricular edema and discuss our case in relation to a review of existing literature pertaining to the radiology of XGRs. To the best of our knowledge, this is the first reported case of bilateral trigonal XGR causing brain edema without ventricular dilatation. Despite the fact that they can cause hydrocephalus, XGRs are silent and benign lesions. Although the etiopathology of XGRs remains poorly understood, enhanced imaging analyses may provide additional information regarding edema and focal white matter signal changes

Limbic Encephalitis Associated with Sjogren's Syndrome: Report of Three Cases

Sjogren's syndrome (SS) may be complicated by neurological manifestations. We herein report three women (age range 26-60 years old) who all presented with limbic encephalitis (LE) as the predominant clinical feature 3 months to 15 years after the diagnosis of SS. The 26-year-old patient also developed acute motor axonal neuropathy one week after autoimmune encephalitis. All three patients showed contrast-enhanced MRI lesions and inflammatory cerebrospinal fluid findings, while not displaying any anti-neuronal antibodies and showing a remarkable response to immunotherapy. SS is often overlooked when the symptoms are mild. Therefore, in LE cases with no identifiable cause, serological screening for rheumatologic disorders is recommended

Glu-370 in the large subunit influences the substrate binding, allosteric, and heat stability properties of potato ADP-glucose pyrophosphorylase

ADP-glucose pyrophosphorylase (AGPase) is a key allosteric enzyme in plant starch biosynthesis. Plant AGPase is a heterotetrameric enzyme that consists of large (LS) and small subunits (SS), which are encoded by two different genes. In this study, we showed that the conversion of Glu to Gly at position 370 in the LS of AGPase alters the heterotetrameric stability along with the binding properties of substrate and effectors of the enzyme. Kinetic analyses revealed that the affinity of the (LSSSWT)-S-E370G AGPase for glucose 1-phosphate is 3-fold less than for wild type (WT) AGPase. Additionally, the (LSSSWT)-S-E370G AGPase requires 3-fold more 3-phosphogyceric acid to be activated. Finally, the LS(E370G)SS(WT)AGPase is less heat stable compared with the WT AGPase. Computational analysis of the mutant Gly-370 in the 3D modeled LS AGPase showed that this residue changes charge distribution of the surface and thus affect stability of the LS AGPase and overall heat stability of the heterotetrameric AGPase. In summary, our results show that LSE370 intricately modulate the heat stability and enzymatic activity of potato the AGPase. (C) 2016 Elsevier Ireland Ltd. All rights reserved

Comparison of a 4-Day versus 2-Day Low Fiber Diet Regimen in Barium Tagging CT Colonography in Incomplete Colonoscopy Patients

Our aim was to compare the amount of residual feces, residual fluid, the tagging quality, and patient compliance using 4-day versus 2-day low fiber diet regimen in barium tagging CT colonography in incomplete colonoscopy patients. Methods. A total of 101 patients who underwent CT colonography were assigned to 2-day diet group (n = 56) and 4-day diet group (n = 45). Fecal tagging was achieved with barium sulphate while bisacodyl and sennoside B were used for bowel preparation. Residual solid stool was divided into two groups measuring = 6 mm. We graded the residual fluid, tagging quality for solid stool, and fluid per bowel segment. We performed a questionnaire to assess patient compliance. Results. 604 bowel segments were evaluated. There was no significant difference between 2-day and 4-day diet groups with respect to residual solid stool, residual fluid, tagging quality for stool, and fluid observed in fecal tag CT colonography (P > 0.05). The prevalence of moderate discomfort was significantly higher in 4-day group (P < 0.001). Conclusion. Our study shows that 2-day limited bowel preparation regimen for fecal tag CT colonography is a safe and reasonable technique to evaluate the entire colon, particularly in incomplete conventional colonoscopy patients