28 research outputs found
Confluent and Reticulated Papillomatosis (Gougerot-Carteaud Syndrome) in Two Brothers
Confluent and reticulate papillomatosis (CRP) is a rare disorder that has mostly been described in case reports and limited case series. It is a benign acquired ichthyosiform dermatosis that is clinically characterized by persistent brown papules and plaques that are confluent centrally and reticulated peripherally. Most of the patients are sporadic but familial cases were also reported. Herein we described CRP in two brothers supporting the hereditary predisposition.</p
Evaluation of the main parameters affecting seismic performance of the RC buildings
Low and mid-rise reinforced concrete (RC) buildings consist of an important portion of the building stock in many earthquake prone countries. Therefore understanding their seismic behaviour is important for mitigation studies. This study aims to evaluate how much and when; seismic code, number of stories, concrete strength, amount of transverse reinforcement and infill-wall contribution parameters are important for seismic performances of RC buildings. Seismic performances of the models reflecting different cases are determined for different performance levels and seismic loading conditions. Based on the considered values of the parameters, it is concluded that: modern code specifications and higher transverse reinforcement 50%, the concrete strength up to 66%, infill-walls 15% and number of story 55% increase the seismic performance for life safety level. Evaluations on the effect of the considered parameters for different performance levels and seismic loadings in relation with other parameters are also given in this paper. © 2014 Indian Academy of Sciences.:107M569 2010FBE098, 2010FBE099, 2008FBE005The authors thank the Scientific and Technical Research Council of Turkey (TUBITAK) under Project No:107M569 and support of Pamukkale University Research Fund Unit (PAU-BAP) under Project No: 2008FBE005, 2010FBE098 and 2010FBE099 for support
In Vitro Investigation of Surface Roughness and Bacterial Adhesion on Different Dental Porcelains Applying Different Vital Whitening Agents
Statement of the problem: Studies on the effects of vital bleaching agents on the surface roughness and bacterial adhesion of different dental por-celain materials are insufficient.Objective: The aim of this study is to determine the effects of vital ble-aching procedures on the surface roughness of different dental porcelains and to investigate whether they facilitate bacterial adhesion.Materials & Methods: A total of 60 porcelain discs, 12 mm in diameter and 2.2 mm in thickness, were produced from two feldspathic porcelains and one leucite-enriched all-ceramic. The sample groups (n=20) manufactured from Ceramco 3, VMK 95, and Finesse TM were named as C, V, and F respectively. Two bleaching agents were applied to 20 samples belonging to C, V and F gro-ups. The group bleached with 16% carbamide peroxide gel was called the N group. The group bleached with 10% carbamide peroxide gel was called the R group. A total of 6 experimental groups, CN, VN, FN, CR, VR and FR, were formed. Streptococcus mutans strain was used to detect bacterial adhesion be-fore and after bleaching on porcelain surfaces with and without a pellicle layer, and adhesion was determined by colony counting method. The obtained data were analyzed with Kruskal-Wallis test and Spearman’s correlation coefficient.Results: The mean difference in bacterial adhesion colony counts of VN and VR groups was found statistically significant (P 0.05).Conclusion: The bleaching process could affect the surface roughness of dental porcelain and facilitate bacterial adhesion to the porcelain surface
Severe myoclonic epilepsy of infancy (Dravet syndrome): Clinical and genetic features of nine Turkish patients
Purpose: Mutations of the a-1 subunit sodium channel gene (SCN1A) cause severe myoclonic epilepsy of infancy (SMEI). To date, over 300 mutations related to SMEI have been described. In the present study, we report new SCN1A mutations and the clinical features of SMEI cases. Materials and Methods: We studied the clinical and genetic features of nine patients diagnosed with SMEI at the Pediatric Neurology Department of Istanbul Medical Faculty. Results: Five patients had nonsense mutations, two had missense mutations, one had a splice site mutation and one had a deletion mutation of the SCN1A gene. Mutations at c.3705+5G splice site, p.trip153X nonsense mutation and deletion at c.2416_2946 have not been previously described. The seizures started following whole cell pertussis vaccination in all patients. The seizures ceased in one patient and continued in the other eight patients. Developmental regression was severe in three patients, with frequent status epilepticus. The type of mutation was not predictive for the severity of the disease. Two of the three patients with severe regression had nonsense and missense mutations. Conclusions : Dravet syndrome can be result of several different types of mutation in SCN1A gene. Onset of the seizures after pertussis vaccination is an important clue for the diagnosis and neuro- developmental delay should be expected in all patients
Comparison of MRI, CA-125 and HE-4 in determining the depth ofmyometrial invasion in cases with endometrial cancer
Vitamin K deficiency - Late onset intracranial haemorrhage
A retrospective study is presented of the clinical features and outcome of late onset haemorrhagic disease due to vitamin K deficiency in 11 babies who were admitted to the emergency or child neurology unit during a 4-year period (January 1994-December 1997). The disease occurred in infants between 30 and 119 days of age (mean: 56 ± 24 days). None of them received vitamin K after birth and all were breastfed. The presenting complaints were seizures (91%), drowsiness (82%), poor sucking (64%), vomiting (46%), fever (46%), pallor (46%), acute diarrhoea (27%), irritability and high-pitched cry (18%). On examination, tense or bulging fontanelle (73%), anisocoria (36%), weak neonatal reflexes (18%), cyanoses (18%) were the most frequent findings. The localizations of the intracranial haemorrhage were as follows: intracerebral (91%), subarachnoid (46%), subdural (27%), and intraventricular (27%). No fatality was observed. However, after a follow-up period ranging from 6 to 48 months (mean: 21 ± 13 months); only three (27%) infants remained neurologically normal. Seizure disorders (73%), severe psychomotor retardation (46%), cerebral palsy (46%) and microcephaly (46%) were observed in the remainder. Hydrocephalus developed in three (27%) babies but none of them required shunt replacement. The value is emphasized of vitamin K prophylaxis in the newborn to reduce the incidence of late onset intracranial haemorrhage and handicap in children