Analysis of energy saving and emission reduction of secondary fiber mill based on data mining

Waste paper recycling is an important way to realize the environmental protection development of the papermaking industry. The quality of the pulp will affect the pulp sales of the secondary fiber paper mills. The waste paper pulp can be adjusted by controlling the pulping process working conditions, but the working conditions of the waste paper pulping process have too many parameters. And the parameters are coupled with each other, it is difficult to control. In order to find the best working conditions and improve the quality of the pulp, this study uses the association rules algorithm to optimize the parameters for the waste paper pulping process. These parameters are power of refiner, waste paper concentration of refiner, the volume of slurry that enters deinked process, deinking agent amount, deinking time, deinking temperature, bleaching agent amount, bleaching time, and bleaching temperature. The test results show that the qualified rate of the pulp produced under the improved working conditions is 92.56%, an increase of 6.93%, and the average electricity consumption per ton of pulp is reduced by 5.76 kWh/t. In addition to potential economic benefits, this method can reduce carbon emissions

Relation of Dietary Carbohydrates Intake to Circulating Sex Hormone-binding Globulin Levels in Postmenopausal Women

Background Low circulating levels of sex hormone‐binding globulin (SHBG) have been shown to be a direct and strong risk factor for type 2 diabetes, cardiovascular diseases, and hormone‐dependent cancers, although the relationship between various aspects of dietary carbohydrates and SHBG levels remains unexplored in population studies. Methods Among postmenopausal women with available SHBG measurements at baseline (n = 11 159) in the Women's Health Initiative, a comprehensive assessment was conducted of total dietary carbohydrates, glycemic load (GL), glycemic index (GI), fiber, sugar, and various carbohydrate‐abundant foods in relation to circulating SHBG levels using multiple linear regressions adjusting for potential covariates. Linear trend was tested across quartiles of dietary variables. Benjamini and Hochberg's procedure was used to calculate the false discovery rate for multiple comparisons. Results Higher dietary GL and GI (both based on total and available carbohydrates) and a higher intake of sugar and sugar‐sweetened beverages were associated with lower circulating SHBG concentrations (all P trend < 0.05; Q ‐values = 0.04,0.01, 0.07, 0.10, 0.01, and <0.0001, respectively). In contrast, women with a greater intake of dietary fiber tended to have elevated SHBG levels (P trend = 0.01, Q ‐value = 0.04). There was no significant association between total carbohydrates or other carbohydrate‐abundant foods and SHBG concentrations. Conclusions The findings suggest that low GL or GI diets with low sugar and high fiber content may be associated with higher serum SHBG concentrations among postmenopausal women. Future studies investigating whether lower GL or GI diets increase SHBG concentrations are warranted

Revisiting the concentration observations and source apportionment of atmospheric ammonia

While China’s Air Pollution Prevention and Control Action Plan on particulate matter since 2013 has reduced sulfate significantly, aerosol ammonium nitrate remains high in East China. As the high nitrate abundances are strongly linked with ammonia, reducing ammonia emissions is becoming increasingly important to improve the air quality of China. Although satellite data provide evidence of substantial increases in atmospheric ammonia concentrations over major agricultural regions, long-term surface observation of ammonia concentrations are sparse. In addition, there is still no consensus on whether agricultural or non-agricultural emissions dominate the urban ammonia budget. Identifying the ammonia source by nitrogen isotope helps in designing a mitigation strategy for policymakers, but existing methods have not been well validated. Revisiting the concentration measurements and identifying source apportionment of atmospheric ammonia is thus an essential step towards reducing ammonia emissions

Lineage tracing for multiple lung cancer by spatiotemporal heterogeneity using a multi-omics analysis method integrating genomic, transcriptomic, and immune-related features

IntroductionThe distinction between multiple primary lung cancer (MPLC) and intrapulmonary metastasis (IPM) holds clinical significance in staging, therapeutic intervention, and prognosis assessment for multiple lung cancer. Lineage tracing by clinicopathologic features alone remains a clinical challenge; thus, we aimed to develop a multi-omics analysis method delineating spatiotemporal heterogeneity based on tumor genomic profiling.MethodsBetween 2012 and 2022, 11 specimens were collected from two patients diagnosed with multiple lung cancer (LU1 and LU2) with synchronous/metachronous tumors. A novel multi-omics analysis method based on whole-exome sequencing, transcriptome sequencing (RNA-Seq), and tumor neoantigen prediction was developed to define the lineage. Traditional clinicopathologic reviews and an imaging-based algorithm were performed to verify the results.ResultsSeven tissue biopsies were collected from LU1. The multi-omics analysis method demonstrated that three synchronous tumors observed in 2018 (LU1B/C/D) had strong molecular heterogeneity, various RNA expression and immune microenvironment characteristics, and unique neoantigens. These results suggested that LU1B, LU1C, and LU1D were MPLC, consistent with traditional lineage tracing approaches. The high mutational landscape similarity score (75.1%), similar RNA expression features, and considerable shared neoantigens (n = 241) revealed the IPM relationship between LU1F and LU1G which were two samples detected simultaneously in 2021. Although the multi-omics analysis method aligned with the imaging-based algorithm, pathology and clinicopathologic approaches suggested MPLC owing to different histological types of LU1F/G. Moreover, controversial lineage or misclassification of LU2’s synchronous/metachronous samples (LU2B/D and LU2C/E) traced by traditional approaches might be corrected by the multi-omics analysis method. Spatiotemporal heterogeneity profiled by the multi-omics analysis method suggested that LU2D possibly had the same lineage as LU2B (similarity score, 12.9%; shared neoantigens, n = 71); gefitinib treatment and EGFR, TP53, and RB1 mutations suggested the possibility that LU2E might result from histology transformation of LU2C despite the lack of LU2C biopsy and its histology. By contrast, histological interpretation was indeterminate for LU2D, and LU2E was defined as a primary or progression lesion of LU2C by histological, clinicopathologic, or imaging-based approaches.ConclusionThis novel multi-omics analysis method improves the accuracy of lineage tracing by tracking the spatiotemporal heterogeneity of serial samples. Further validation is required for its clinical application in accurate diagnosis, disease management, and improving prognosis

An Image Compression Encryption Algorithm Based on Chaos and ZUC Stream Cipher

In order to improve the transmission efficiency and security of image encryption, we combined a ZUC stream cipher and chaotic compressed sensing to perform image encryption. The parallel compressed sensing method is adopted to ensure the encryption and decryption efficiency. The ZUC stream cipher is used to sample the one-dimensional chaotic map to reduce the correlation between elements and improve the randomness of the chaotic sequence. The compressed sensing measurement matrix is constructed by using the sampled chaotic sequence to improve the image restoration effect. In order to reduce the block effect after the parallel compressed sensing operation, we also propose a method of a random block of images. Simulation analysis shows that the algorithm demonstrated better encryption and compression performance

Study on the Properties and Synergistic Antioxidant Effects of Novel Bifunctional Fusion Proteins Expressed Using the UTuT6 System

Important antioxidant enzymes, glutathione peroxidase (GPx) and superoxide dismutase (SOD), are involved in maintaining redox balance. They can protect each other and result in more efficiently removing excessive reactive oxygen species (ROS), protecting cells against injury, and maintaining the normal metabolism of ROS. In this study, human cytosolic GPx (hGPx1) and human phospholipid hydroperoxide GPx (hGPx4) genes were integrated into the same open reading frame with human extracellular SOD active site (SOD3-72P) genes, respectively, and several novel fusion proteins were obtained by using the UTuT6 expression system for the first time. Among them, Se-hGPx1UAG-L4-SOD3-72P is the bifunctional fusion protein with the highest GPx activity and the best anti-hydrogen peroxide inactivation ability thus far. The Se-hGPx4UAG-L3-SOD3-72P fusion protein exhibits the strongest alkali and high temperature resistance and a greater protective effect against lipoprotein peroxidation damage. Se-hGPx1UAG-L4-SOD3-72P and Se-hGPx4UAG-L3-SOD3-72P fusion proteins both have good synergistic and antioxidant abilities in H2O2-induced RBCs and liver damage models. We believe that this research will help with the development of novel bifunctional fusion proteins and the investigation of the synergistic and catalytic mechanisms of GPx and SOD, which are important in creating novel protein therapeutics

Visual Secure Image Encryption Scheme Based on Compressed Sensing and Regional Energy

The network security transmission of digital images needs to solve the dual security problems of content and appearance. In this paper, a visually secure image compression and encryption scheme is proposed by combining compressed sensing (CS) and regional energy. The plain image is compressed and encrypted into a secret image by CS and zigzag confusion. Then, according to the regional energy, the secret image is embedded into a carrier image to obtain the final visual secure cipher image. A method of hour hand printing (HHP) scrambling is proposed to increase the pixel irrelevance. Regional energy embedding reduce the damage to the visual quality of carrier image, and the different embedding positions between images greatly enhances the security of the encryption algorithm. Furthermore, the hyperchaotic multi-character system (MCS) is utilized to construct measurement matrix and control pixels. Simulation results and security analyses demonstrate the effectiveness, security and robustness of the propose algorithm

Effects of hypoxia on survival, behavior, metabolism and cellular damage of Manila clam (Ruditapes philippinarum).

The Manila clam Ruditapes philippinarum has become a common and dominant macrobenthic species in coastal areas of the northwestern Pacific and temperate waters of Europe; it is also a major cultured shellfish, with annual worldwide production exceeding 3.3 million tonnes. This species faces greater risk of exposure to hypoxia as eutrophication worsens throughout its coastal habitats; however, its tolerance to hypoxia remains unclear, and the toxicological indicators including LC50 and LT50 have not yet been assessed. Previous studies on the effects of hypoxia on marine benthos have focused largely on functional responses, such as metabolism and gene expression, leaving potential structural damage to the mitochondria or the cells unknown. In this study we assessed the effects of hypoxia on Manila clam in terms of survival, behavior, metabolism and cellular damage, using a newly designed automated hypoxia simulation device that features exceptional accuracy and good stability. The clams exhibited strong tolerance to hypoxia as the 20-day LC50 for dissolved oxygen (DO) was estimated to be 0.57 mg L-1, and the LT50 at 0.5 mg L-1 DO was 422 hours. Adaptations included fewer buried clams and a depressed metabolism, while the unexpected rise in the activities of key enzymes involved in glycolysis may indicate a diverse strategy of shellfish under hypoxia. Cellular damage was observed as collapse of the mitochondrial cristae and both cellular and mitochondrial vacuolization. This multi-level study complements and updates our knowledge of the effects of hypoxia on marine benthos, by improving our understanding of the potential for marine ecological transformation under hypoxic conditions and providing useful information for Manila clam farming

Influence of Prolonged Visual Display Terminal Use and Exercise on Physical and Mental Conditions of Internet Staff in Hangzhou, China

To examine the effects of prolonged visual display terminal (VDT) working hours and exercise frequency on VDT-related symptoms, we recruited 944 Chinese internet staff for the study. A self-administered questionnaire survey was used to obtain the hours of daily VDT work, exercise frequency, and the physical and mental health of the participants. The daily VDT working time of participants was 8.7 hours. Musculoskeletal pain and eye complaints were prevalent, and the participants had poor mental health status. When daily VDT operation time was more than 11 hours, VDT-related symptoms, including backache (odds ratios (OR) = 3.59), wrist pain (OR = 1.88), hip pain (OR = 2.42), dry eyes (OR = 2.22), and ocular soreness (OR = 2.16) were more likely to occur, and an increased risk of serious occupational stress (OR = 6.75) and job burnout (OR = 2.66) was found in internet workers. Compared with those who never exercised, appropriate exercise frequency (three times per week) was helpful to relieve pain in the shoulders (OR = 0.28), neck (OR = 0.45), back (OR = 0.30), lower back (OR = 0.25), and wrists (OR = 0.38), as well as to prevent vision loss (OR = 0.33) and job burnout (OR = 0.42). Therefore, avoiding excessive VDT exposure and performing moderate exercise could protect the physical and mental health of internet staff from the adverse effects of VDT

Sustainable iridescence of cast and shear coatings of cellulose nanocrystals

As an eco-friendly sustainable iridescent coating, cholesteric cellulose nanocrystal (CNC) is susceptible to substrate effects or shearing effects. In this work, interface interaction and liquid crystal phase transition were evaluated for fabricating iridescent cast or shear coatings of CNCs onto substrates of polystyrene, glass, ceramic, wood, stainless steel, metal, or metal alloy. Three types of substrate effects and four categories of shearing effects on the structure color mechanism of CNC coatings were proposed. Practically, several efficient approaches, such as increasing colloidal concentration, enhancing water-retention of substrates, raising processing temperature, slowing down shearing speed, or doping functional additives were involved. Hence, a feasible strategy was provided for preparing sustainable, iridescent, stable, and industrially scalable coatings of CNCs