9 research outputs found
Implementation of a clinical guideline for detection of gestational diabetes in primary care
Background: Gestational diabetes (GD) impacts maternal and fetal morbidity.
In 2012, the World Diabetes Foundation provided financing project in
Barranquilla (Colombia), aimed to implement a clinical guide for the diagnosis
and treatment of this condition. Aim: To estimate the adherence of the guide
in primary care centers. Material and Methods: A Cross-sectional study of
pregnant women suspected of having gestational diabetes. Pregnant women
were classified according to the week of admission to the prenatal control program:
< week 24 or later. Women with a fasting blood glucose over 92 mg/dL
and under 126 mg/dL or with some positive result to the oral glucose tolerance
test were included. Results: Nine percent (1,887 women) of 21,699 registries of
pregnant women, were at risk for gestational diabetes. Of these, 1,880 registries
with complete data were analyzed. Sixty nine entered the program at less than
24 weeks of pregnancy and 71% had had a fasting blood glucose measured in
the first control. In 69.2% of these women, criteria for gestational diabetes was
met. A glucose tolerance test was suggested to women with a blood glucose below
92 mg/dl. Among 72% of the latter, the glucose tolerance test met the criteria for
gestational diabetes. Among the 498 women who entered the program after 24
weeks of gestation, 68% met the criteria for gestational diabetes with the fasting
blood glucose levels. In 90 women, a glucose tolerance test was performed and 80%
met the criteria for gestational diabetes. Conclusions: An adequate adherence
to guidelines favors the detection of pregnant women with gestational diabetes
Relación entre la práctica de actividad física en embazadas y diabetes gestacional: un estudio transversal
Objetivo: Determinar la relación entre la práctica de actividadfísica durante el embarazo y el diagnóstico de diabetesgestacional.Métodos: Estudio de corte transversal en 579 gestantes.Se evaluó la actividad física, etapas de cambio y la percepciónde barreras para realizar actividad física. Se realizó laprueba de tolerancia oral a la glucosa (PTOG), con cargaoral de 75 gr en ayunas.Resultados: La frecuencia de actividad física fue 30,9%.La inactividad física [OR 2,6 (IC 95% 1,5-4,4)], la falta detiempo [OR 11,9 (IC 95% 1,6-87,7)], y el miedo a lesionarse[OR 4,3 (IC 95% 1,3-14)] son un riesgo para desarrollardiabetes gestacional. Existen diferencias en los valoresde glicemia entre las activas e inactivas físicamente(p<0,001), glicemia basal (96,5 ± 0,7 vs. 108,3 ± 27,2);a una hora de la prueba oral (143,3 ± 14,1 vs. 158,4 ±59,9); y a dos horas de la prueba oral (122,6 ± 25,8 vs.140 ± 66).Conclusión: La inactividad física es un factor de riesgo parala diabetes gestacional y altos niveles de glicemia son evidentesen las mujeres embarazadas inactivas físicamente
Capitulo 3. Ciencias Sociales, Artes y Humanidades
La investigación busca describir los significados psicológicos en relación con la felicidad, partiendo del sujeto común no experto en la materia. Para ello se utilizará la técnica de Redes Semánticas Naturales Modificadas (RSNM). Esto en el contexto de la UNAD Zona Sur, específicamente con el cuerpo docente de las diferentes escuelas académicas, excepto los que pertenecen al programa de psicología. Esta última decisión en razón a prevenir alguna influencia en los significados derivada de la formación disciplinar de tales docentes, téngase en cuenta que el tema de la felicidad ha sido objeto de estudio desde la psicología.
Este es un estudio sobre los significados psicológicos acerca de la felicidad en docentes de la UNAD Zona Sur. Esto a través de la técnica de RSNM, la cual se orienta justamente a dicho propósito. Esto en articulación con el proyecto “Felicidad: un estudio mixto desde la perspectiva de docentes y estudiantes de psicología de dos universidades de Latinoamérica”, en el que vienen trabajando docentes de la UNAD en convenio con la UNAM (Universidad Nacional Autónoma de México)
Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2
The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality
Implementation of a clinical guideline for detection of gestational diabetes in primary care
Background: Gestational diabetes (GD) impacts maternal and fetal morbidity.
In 2012, the World Diabetes Foundation provided financing project in
Barranquilla (Colombia), aimed to implement a clinical guide for the diagnosis
and treatment of this condition. Aim: To estimate the adherence of the guide
in primary care centers. Material and Methods: A Cross-sectional study of
pregnant women suspected of having gestational diabetes. Pregnant women
were classified according to the week of admission to the prenatal control program:
< week 24 or later. Women with a fasting blood glucose over 92 mg/dL
and under 126 mg/dL or with some positive result to the oral glucose tolerance
test were included. Results: Nine percent (1,887 women) of 21,699 registries of
pregnant women, were at risk for gestational diabetes. Of these, 1,880 registries
with complete data were analyzed. Sixty nine entered the program at less than
24 weeks of pregnancy and 71% had had a fasting blood glucose measured in
the first control. In 69.2% of these women, criteria for gestational diabetes was
met. A glucose tolerance test was suggested to women with a blood glucose below
92 mg/dl. Among 72% of the latter, the glucose tolerance test met the criteria for
gestational diabetes. Among the 498 women who entered the program after 24
weeks of gestation, 68% met the criteria for gestational diabetes with the fasting
blood glucose levels. In 90 women, a glucose tolerance test was performed and 80%
met the criteria for gestational diabetes. Conclusions: An adequate adherence
to guidelines favors the detection of pregnant women with gestational diabetes
Relationship between physical activity in pregnant and gestational diabetes: cross-sectional study
Objetivo: Determinar la relación entre la práctica de actividad
física durante el embarazo y el diagnóstico de diabetes
gestacional.
Métodos: Estudio de corte transversal en 579 gestantes.
Se evaluó la actividad física, etapas de cambio y la percepción
de barreras para realizar actividad física. Se realizó la
prueba de tolerancia oral a la glucosa (PTOG), con carga
oral de 75 gr en ayunas.
Resultados: La frecuencia de actividad física fue 30,9%.
La inactividad física [OR 2,6 (IC 95% 1,5-4,4)], la falta de
tiempo [OR 11,9 (IC 95% 1,6-87,7)], y el miedo a lesionarse
[OR 4,3 (IC 95% 1,3-14)] son un riesgo para desarrollar
diabetes gestacional. Existen diferencias en los valores
de glicemia entre las activas e inactivas físicamente
(p<0,001), glicemia basal (96,5 ± 0,7 vs. 108,3 ± 27,2);
a una hora de la prueba oral (143,3 ± 14,1 vs. 158,4 ±
59,9); y a dos horas de la prueba oral (122,6 ± 25,8 vs.
140 ± 66).
Conclusión: La inactividad física es un factor de riesgo para
la diabetes gestacional y altos niveles de glicemia son evidentes
en las mujeres embarazadas inactivas físicamente.Objective: To determine the relationship between physical
activity during pregnancy and the diagnosis of gestational
diabetes.
Methods: A cross-sectional study performed in 579 cases
of pregnant. Levels of physical activity, different stages of
change, and perception of barriers for the performance
of physical activity were evaluated. In week 24 an oral
glucose tolerance test (PTOG) was performed with an oral
load of 75 gr in fasting.
Results: The frequency of physical activity of the participants
was 30,9%. Physical inactivity [OR 2,6 (IC 95% 1,5-
4,4)], lack of time [OR 11,9 (IC 95% 1,6-87,7)], and fear
to be injured [OR 4,3 (IC 95% 1,3-14)] are a risk to develop
diabetes during pregnancy. The glycaemia values were
significantly different (p<0,05) between women physically
active and those inactive, being the basal glycaemia (96.5
± 0.7 vs. 108.3 ± 27.2); glycemia one hour after the oral
test (143.3 ± 14.1 vs. 158.4 ± 59.9) and glycemia two
hours after the oral test (122.6 ± 25.8 vs.140 ± 66).
Conclusion: Physical inactivity is a risk factor for diabetes
during the pregnancy period and high glycaemia levels are
evident in pregnant women with physical inactivity
Empresa, Construcción de Paz y Sostenibilidad (Agenda 2030): desafíos desde la óptica del derecho
A partir del proyecto de investigación “Modelo integrador de construcción de paz desde la familia, la educación y la empresa para la reconciliación y el ejercicio de los derechos humanos en el departamento de Sucre”, desarrollado por investigadores de la línea de derecho privado del Grupo de Investigación Sociojurídica de la Corporación Universitaria del Caribe CECAR en construcción con investigadores grupos de investigación e instituciones aliadas, se presentan los resultados en la presente publicación, en la cual desde la problematización en la que se cimento la indagación sobre la articulación de actores interdisciplinares, se identifican los fundamentos del escenario construcción de paz y sostenibilidad desde la óptica del derecho