Tipología de fincas, capital social y cobertura arbórea en el cañón de Anaime (Tolima)

La tipología de fincas es un procedimiento para diferenciar grupos por características socioeconómicas y biofísicas de los sistemas de producción. Con base a una tipificación se pueden establecer grupos que constituyen sujetos de análisis e intervención bajo diferentes estrategias. Esto podría constituir la base de dominios de recomendación. El objetivo de este estudio fue realizar la tipificación de la población estudio constituido por 30 fincas localizadas en el cañón de Anaime, Cajamarca. Se diferenciaron dos tipos de fincas: grandes y chicas. En C1 predominan los predios grandes, con una área promedio de 158±107,3 ha. Es notorio que el capital social es más fuerte en el C2. El 72% de las fincas del C2, reportaron siembra de árboles, en diferentes arreglos agroforestales. Se concluye que los predios más pequeños poseen una mayor dinámica ambiental y económica

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

The original version of this article unfortunately contained a mistake

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Caracterización de la elección de carreras universitarias en alumnos de undécimo grado de los colegios privados acoandes, adventista la libertad, afelsa, americano, alejandro galvis galvis, bucaramanga, cajasan tejados, cooperativo bucaramanga, cooperativo comfenalco, cooprofesores, divino amor, divino niño, fernando aragón, instituto andino, instituto santa maría micaela, integrado “jorge isaac”, josé acevedo y gómez, juan josé rondon, maría auxiliadora, nuestra señora del transito, presentación, príncipe asturias, príncipe san carlos, psicopedagógico carl rogers, sabio caldas, santa maría maggiore, sagrado corazón de jesús “bethlemitas”, santandereano de comercio, santa teresita del niño jesús, san vicente ferrer, sotomayor, u. C. C., virrey solís de bucaramanga

El estudio investigativo sobre caracterización en la elección de carreras universitarias en alumnos de undécimo grado de los 33 colegios privados de Bucaramanga, desea encontrar respuestas a este planteamiento en ese contexto. La decisión de elegir una carrera universitaria, afecta a los estudiantes interesados en continuar sus estudios superiores, a los colegios de bachillerato, a las universidades, a las municipalidades, a las entidades rectoras de la educación en Colombia como el Ministerio de Educación, secretarias de educación departamentales, secretarias de educación municipales; y sobre todo a la sociedad en general. Se necesita saber qué desean estudiar en la universidad los aspirantes y por qué eligen determinada carrera. En tal sentido, la investigación se desarrolla en forma descriptiva. La delimitación de la investigación se enmarco en el universo a los estudiantes de undécimo grado de todos los 33 colegios privados de la ciudad de Bucaramanga, mediante un muestreo aleatorio estratificado y representativo de cada colegio. Se espera llegar a conocer el comportamiento de las variables referidas a sexo, edad, estado civil, actividad laboral, tiempo libre, características personales, aspectos familiares, aspectos económicos, información académica y aspiración a estudios superiores; y las carreras profesionales que se desean estudiar en la universidad. El objetivo final es saber las preferencias de la muestra estudiada, estableciendo un orden de mayor a menor de las carreras elegidas.1. Problemas y objetivos. -- 1.1 descripción del problema. -- 1.2 formulación del problema. -- 1.3 justificación. -- 1.4 objetivos. -- 1.4.1 objetivo general. -- 1.4.2 objetivos específicos. -- 2. Sustento teórico. -- 3. Desarrollo metodológico. -- 3.1 encuesta. -- 3.1.1 instrumento de medición. -- 3. 1. 2 métodos de supervisión. -- 3.1.3 método de muestreo. -- 3. 1. 4 tamaño de la muestra. -- 3.1.5 trabajo de campo. -- 3.2 procesamiento de la información. -- 3.3 análisis de resultados. -- 4. Caracterización de los estudiantes aspirantesa ingresar a estudiar una carrera universitaria. -- 4.1 sexo. -- 4.2 edad. -- 4.3 estado civil. -- 4.4 trabajo extra escolar. -- 4.5 tiempo libre. -- 4.6 cualidades o características. -- 4.7 núcleo familiar. -- 4.8 condición de los padres. -- 4.9 nivel de estudios de los padres. -- 4.9.1 nivel de estudios de la madre. -- 4.9.2 nivel de estudios del padre. -- 4.10 actividad económica de los padres. -- 4.10.1 actividad económica de la madre. -- 4.10.2 actividad económica del padre. -- 4.11 residencia. -- 4.12 ingresos económicos del núcleo familiar. -- 4.13 materias o asignaturas que mas se le facilitan. -- 4.14 continuación de estudios superiores. -- 4.15 modalidad. -- 4.16 jornada. -- 4.17 tipo de educación. -- 4.18 financiación de los estudios. -- 4.19 tipo de institución. -- 4.20 lugar en el que le gustaría estudiar. -- 4.21 carrera que desea estudiar. -- 5. Tabulación cruzada. -- 5.1 tabulación cruzada por sexo. -- 5.2 tabulación cruzada por edad. -- 5.3 tabulación cruzada por estado civil. -- 5.4 tabulación cruzada por actividad extra escolar. -- 5.5 tabulación cruzada por tiempo libre. -- 5.6 tabulación cruzada cualidades o características. -- 5.7 tabulación cruzada núcleo familiar. -- 5.8 tabulación cruzada condición de los padres. -- 5.9 tabulación cruzada nivel de estudio de los padres. -- 5.9.1 tabulación cruzada nivel de estudios de la madre. -- 5.9.2 tabulación cruzada nivel de estudios del padre. -- 5.10 tabulación cruzada actividad económica de los padres. --5.10.1 tabulación cruzada actividad económica de la madre. -- 5.10.1 tabulación cruzada actividad económica del padre. -- 5.11 tabulación cruzada reside en casa. -- 5.12 tabulación cruzada ingresos del núcleo familiar. -- 5.13 tabulación cruzada de materias que mas se le facilitan. -- 5.14 tabulación cruzada continuación de estudios superiores. -- 5.15 tabulación cruzada modalidad. -- 5.16 tabulación cruzada jornada. -- 5.17 tabulación cruzada tipo de educación. -- 5.18 tabulación cruzada financiación. -- 5.19 tabulación cruzada tipo de institución. -- 5.20 tabulación cruzada lugar en el que le gustaría. -- estudiar. -- conclusiones. – bibliografí[email protected]@[email protected]@campusucc.edu.cosocorrodelpilar.gonzá[email protected]@[email protected]@[email protected]@[email protected]@[email protected]@[email protected]@campusucc.edu.cosergio.serrano@[email protected]@[email protected]í[email protected]@[email protected]@campusucc.edu.coronald.martí[email protected]@[email protected]@[email protected]@[email protected]@[email protected]í[email protected]

Efficacy and safety of the CVnCoV SARS-CoV-2 mRNA vaccine candidate in ten countries in Europe and Latin America (HERALD): a randomised, observer-blinded, placebo-controlled, phase 2b/3 trial

Background: Additional safe and efficacious vaccines are needed to control the COVID-19 pandemic. We aimed to analyse the efficacy and safety of the CVnCoV SARS-CoV-2 mRNA vaccine candidate. Methods: HERALD is a randomised, observer-blinded, placebo-controlled, phase 2b/3 clinical trial conducted in 47 centres in ten countries in Europe and Latin America. By use of an interactive web response system and stratification by country and age group (18–60 years and ≥61 years), adults with no history of virologically confirmed COVID-19 were randomly assigned (1:1) to receive intramuscularly either two 0·6 mL doses of CVnCoV containing 12 μg of mRNA or two 0·6 mL doses of 0·9% NaCl (placebo) on days 1 and 29. The primary efficacy endpoint was the occurrence of a first episode of virologically confirmed symptomatic COVID-19 of any severity and caused by any strain from 15 days after the second dose. For the primary endpoint, the trial was considered successful if the lower limit of the CI was greater than 30%. Key secondary endpoints were the occurrence of a first episode of virologically confirmed moderate-to-severe COVID-19, severe COVID-19, and COVID-19 of any severity by age group. Primary safety outcomes were solicited local and systemic adverse events within 7 days after each dose and unsolicited adverse events within 28 days after each dose in phase 2b participants, and serious adverse events and adverse events of special interest up to 1 year after the second dose in phase 2b and phase 3 participants. Here, we report data up to June 18, 2021. The study is registered at ClinicalTrials.gov, NCT04652102, and EudraCT, 2020–003998–22, and is ongoing. Findings: Between Dec 11, 2020, and April 12, 2021, 39 680 participants were enrolled and randomly assigned to receive either CVnCoV (n=19 846) or placebo (n=19 834), of whom 19 783 received at least one dose of CVnCoV and 19 746 received at least one dose of placebo. After a mean observation period of 48·2 days (SE 0·2), 83 cases of COVID-19 occurred in the CVnCoV group (n=12 851) in 1735·29 person-years and 145 cases occurred in the placebo group (n=12 211) in 1569·87 person-years, resulting in an overall vaccine efficacy against symptomatic COVID-19 of 48·2% (95·826% CI 31·0–61·4; p=0·016). Vaccine efficacy against moderate-to-severe COVID-19 was 70·7% (95% CI 42·5–86·1; CVnCoV 12 cases in 1735·29 person-years, placebo 37 cases in 1569·87 person-years). In participants aged 18–60 years, vaccine efficacy against symptomatic disease was 52·5% (95% CI 36·2–64·8; CVnCoV 71 cases in 1591·47 person-years, placebo, 136 cases in 1449·23 person-years). Too few cases occurred in participants aged 61 years or older (CVnCoV 12, placebo nine) to allow meaningful assessment of vaccine efficacy. Solicited adverse events, which were mostly systemic, were more common in CVnCoV recipients (1933 [96·5%] of 2003) than in placebo recipients (1344 [67·9%] of 1978), with 542 (27·1%) CVnCoV recipients and 61 (3·1%) placebo recipients reporting grade 3 solicited adverse events. The most frequently reported local reaction after any dose in the CVnCoV group was injection-site pain (1678 [83·6%] of 2007), with 22 grade 3 reactions, and the most frequently reported systematic reactions were fatigue (1603 [80·0%] of 2003) and headache (1541 [76·9%] of 2003). 82 (0·4%) of 19 783 CVnCoV recipients reported 100 serious adverse events and 66 (0·3%) of 19 746 placebo recipients reported 76 serious adverse events. Eight serious adverse events in five CVnCoV recipients and two serious adverse events in two placebo recipients were considered vaccination-related. None of the fatal serious adverse events reported (eight in the CVnCoV group and six in the placebo group) were considered to be related to study vaccination. Adverse events of special interest were reported for 38 (0·2%) participants in the CVnCoV group and 31 (0·2%) participants in the placebo group. These events were considered to be related to the trial vaccine for 14 (<0·1%) participants in the CVnCoV group and for five (<0·1%) participants in the placebo group. Interpretation: CVnCoV was efficacious in the prevention of COVID-19 of any severity and had an acceptable safety profile. Taking into account the changing environment, including the emergence of SARS-CoV-2 variants, and timelines for further development, the decision has been made to cease activities on the CVnCoV candidate and to focus efforts on the development of next-generation vaccine candidates. Funding: German Federal Ministry of Education and Research and CureVac

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study (Intensive Care Medicine, (2021), 47, 2, (160-169), 10.1007/s00134-020-06234-9)

The original version of this article unfortunately contained a mistake. The members of the ESICM Trials Group Collaborators were not shown in the article but only in the ESM. The full list of collaborators is shown below. The original article has been corrected