2,710 research outputs found
Case Report: Acute generalised exanthematous pustulosis secondary to cotrimoxazole or tenofovir
Cutaneous adverse drug reactions are a common complication of antiretroviral therapy and of drugs used to treat opportunistic infections. We present a rare case of acute generalised exanthematous pustulosis secondary to  cotrimoxazole or tenofovir
Acute generalised exanthematous pustulosis secondary to cotrimoxazole or tenofovir
Cutaneous adverse drug reactions are a common complication of antiretroviral therapy and of drugs used to treat opportunistic infections. We present a rare case of acute generalised exanthematous pustulosis secondary to cotrimoxazole or tenofovir
A chain rule for the expected suprema of Gaussian processes
The expected supremum of a Gaussian process indexed by the image of an index
set under a function class is bounded in terms of separate properties of the
index set and the function class. The bound is relevant to the estimation of
nonlinear transformations or the analysis of learning algorithms whenever
hypotheses are chosen from composite classes, as is the case for multi-layer
models
Twirling Elastica: Kinks, Viscous Drag, and Torsional Stress
Biological filaments such as DNA or bacterial flagella are typically curved
in their natural states. To elucidate the interplay of viscous drag, twisting,
and bending in the overdamped dynamics of such filaments, we compute the
steady-state torsional stress and shape of a rotating rod with a kink. Drag
deforms the rod, ultimately extending or folding it depending on the kink
angle. For certain kink angles and kink locations, both states are possible at
high rotation rates. The agreement between our macroscopic experiments and the
theory is good, with no adjustable parameters.Comment: 4 pages, 4 figure
The Viscous Nonlinear Dynamics of Twist and Writhe
Exploiting the "natural" frame of space curves, we formulate an intrinsic
dynamics of twisted elastic filaments in viscous fluids. A pair of coupled
nonlinear equations describing the temporal evolution of the filament's complex
curvature and twist density embodies the dynamic interplay of twist and writhe.
These are used to illustrate a novel nonlinear phenomenon: ``geometric
untwisting" of open filaments, whereby twisting strains relax through a
transient writhing instability without performing axial rotation. This may
explain certain experimentally observed motions of fibers of the bacterium B.
subtilis [N.H. Mendelson, et al., J. Bacteriol. 177, 7060 (1995)].Comment: 9 pages, 4 figure
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Application of Design of Experiments (DOE) on the Processing of Rapid Prototyped Samples
The purpose of this experiment was to improve the Fused Deposition Modeling Process by
examining the tensile strength of samples fabricated in a Stratasys FDM 1650 Machine utilizing
the methods of Design of Experiments. A two-level, four-factor, full factorial experiment was
conducted. The selected factors were temperature, air gap, slice thickness, and raster orientation.
A regression equation determined the level each factor should be set in order to optimize the
FDM machine settings. It was found that single factors - small air gap, small layer thickness
and low raster orientation, as well as the interaction between high temperature and small layer
thickness yielded the greatest effect the response.Mechanical Engineerin
Inclusive Masculinity and Facebook Photographs Among Early Emerging Adults at a British University
Central to debates about the construction of masculinity in sociology is the influence of culture and what constitutes acceptable displays of masculinity. This article adopts a novel approach in examining this question. It adopts a summative content analysis, combined with a semiotic analysis, of 1,100 Facebook photographs, in order to explore the underlying meanings within the photos and the performances of masculinity. Facebook photographs from 44, straight, White, male, early emerging adults attending the same university are used as a representation of an individual’s ideal self. These are then analyzed in order to determine the behaviors endorsed by peer culture. It was found that the sample overwhelmingly adopted inclusive behaviors (including homosocial tactility, dancing, and kissing each other), and inclusive masculinity theory was utilized to contextualize participants’ constructions of masculinity. Thus, this research shows that emerging adult males at this university construct their masculine identities away from previous orthodox archetypes. It is argued that the reducing importance of gendered behavior patterns may represent an adoption of what are perceived as wider cultural norms and act as a symbol of adulthood to these early emerging adults
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Effects of Cryogenic Processing on Rapid Prototyping Materials (DSMSomos-8110 and DuraForm PA)
This research investigates the effects of cryogenic processing on the properties of rapid
prototyped materials. Not much research has been done on the post-processing (aging) of rapid
prototyped (RP) polymers at temperatures below 159K (–173˚F). Test specimens of RP
thermoplastic resin DSM-Somos 8110 and DuraformPA Nylon were fabricated and
cryogenically aged from 5-30 hours. The tensile strength and impact toughness were measured.
The goal of this work was to study the effect of cryogenic aging on yield strength and ductility.
This research investigated (1) the cryogenic aging of DSM-Somos 8110 and DuraformPA Nylon,
(2) the effects of controlled ramp-downs/ups on the ultimate and tensile strengths of samples, (3)
the experimental methods, and (4) the analysis and interpretation of the data.Part of this work was funded by a NSF Grant under Research Experiences for
Undergraduates.Mechanical Engineerin
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