Os partidos políticos e a concepção democrática da ordem jurídica constitucional

Trata da matéria dos partidos políticos, correlacionando-a com a natureza democrática da Federação Brasileira, e destaca os institutos da filiação e disciplina partidárias. Aborda a concepção e o estudo do Estado Democrático de Direito, explicitando seus princípios basilares

Primary myelofibrosis: current therapeutic options

AbstractPrimary myelofibrosis is a Philadelphia-negative myeloproliferative neoplasm characterized by clonal myeloid expansion, followed by progressive fibrous connective tissue deposition in the bone marrow, resulting in bone marrow failure. Clonal evolution can also occur, with an increased risk of transformation to acute myeloid leukemia. In addition, disabling constitutional symptoms secondary to the high circulating levels of proinflammatory cytokines and hepatosplenomegaly frequently impair quality of life. Herein the main current treatment options for primary myelofibrosis patients are discussed, contemplating disease-modifying therapeutics in addition to palliative measures, in an individualized patient-based approach

Diálogos entrefronteras: deseo y violencia en Guillermo GómezPeña y David Aniñir

IX Congresso Brasileiro de Hispanistas realizado nos dias 22 a 25 agosto 2016El desarrollo del capitalismo en las sociedades poscoloniales ha sido acompañado en todo el mundo por nuevas orientaciones para la colonialidad del poder y por migraciones, tanto internas como internacionales (CANCLINI, 1989; CORNEJO POLAR, 1996 ). Las “zonas de contacto” (PRATT, 1997) se han multiplicado, principalmente en las zonas urbanas, y se establecen como un espacio conflictivo y articulador de tiempos y espacios distintos. Así como indica Avtar Brah (1996), las colonizaciones son experiencias de violencia que ocurren de diferentes maneras en cada tiempo/espacio, de esa forma es también posible afirmar que las ciudades poscoloniales y las fronteras que en ellas están circunscritas son vividas y trabajadas artísticamente de diferentes formas. En este ensayo propondremos una lectura de esas heterogeneidades relativas a partir de los conceptos de “deseo” y “violencia” contenidos en el sentido propio de la colonización (YOUNG, 1995) en las obras del performerescritor chicano Guillermo GómezPeña, en Estados Unidos y del poeta mapuche David Aniñir, desde la periferia de la ciudad de Santiago, Chile. Los dos autores que, hablando desde las más distintas fronteras, articulan, en sus obras artísticas desde diferentes posiciones, los conflictos y negociaciones en los márgenes de las ciudades globales en la contemporaneidadUNILA­-UNIOEST

Acuidade visual em alunos de 1ª a 6ª séries da escola municipal Mâncio Costa, Ratones, Florianópolis, e sua relação com desempenho escolar.

Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina. Departamento de Saúde Pública

Literatura, fronteras y (pos) colonialidades en América Latina: una mirada hacia la obra Mapurbe Venganza a Raíz, de David Aniñir Guiltaro

IX Congresso Brasileiro de Hispanistas realizado nos dias 22 a 25 agosto 2016Con el desarrollo del capitalismo en el mundo colonial/moderno los homogeneizadores proyectos literarios nacionales abrenespacio para obras de grupos y autores particulares que escriben desde la realidad rota de una América Latina poscolonial.Las fronteras, además de haberse convertido el enfoque de diversos estudios, fueron artísticamente abordadas por artistas de distintas nacionalidades, etnias y (in)habitantes de distintos espacios/tiempos, constituyendo una forma estética contradictoria y heterogénea que acompaña, más allá de la creatividad artística, los sobrepuestos diseños enunciativos articulados en el seno de las distintas colonizaciones y experiencias/vivencias de sus autores. El Poemario Mapurbe. Venganza a Raíz, del escritor Mapuche David Aniñir (2004), es una de esas obras que nos habla desde el espacio conflictivo que es el ser mapuche en las periferias de Santiago y trabaja, en su propio texto, esta condición anfíbia de entrelugar. En este ensayo buscamos identificar, interpretar y analizar algunos procesos de hibridación/transculturación en la contemporánea obra. Entre los procesos observados, destacamos el trabajo con el lenguaje, la elección y la organización de temas, cosmovisión y la estructuración de la obra, comprendidos de manera interdependiente para la articulación creadora de un tercer espacio discursivo y literarioUNILA­-UNIOEST

Impacto de la publicidad en Facebook, TikTok e Instagram en la comunidad de Arlington VA

This paper is a product of the research about “Advertisement impact in Facebook, Tik Tok and Instagram in Arlington Virginia community” developed in the Francisco Jose de Caldas University in 2022. Introduction: Over time, generations have been changing and developing new consumer trends. In the same way, companies have been evolving to be able to adapt to the different trends to reach the target audience using diverse ways of advertising. Method: This paper makes use of databases such as Scopus, Google Scholar, Index-K as sources of information to guide the research of social media use. Using statistics and articles we determine the main aspects that guide the behavior and the use of the different social media platforms in the different age groups. Results: This Paper shows that depending on the age group the use of social media is different; the youngest users prefer platforms where they can share videos or images. Conclusions: As people grow, people are more attracted by platforms like Facebook where they can find social interaction, information and they can share different type of content. Limitation: This paper is focused on people that live in Arlington a small city in the state of Virginia. The information found can be a basis for analyzing users\u27 behaviors on different platforms.Este artículo es producto de la investigación sobre “Impacto de la publicidad en Facebook, Tik Tok e Instagram en la comunidad de Arlington Virginia” desarrollada en la Universidad Francisco José de Caldas en el año 2022. Introducción: Con el paso del tiempo, las generaciones han ido cambiando y desarrollando nuevas tendencias de consumo. Del mismo modo, las empresas han ido evolucionando para poder adaptarse a las diferentes tendencias para llegar al público objetivo utilizando diversas formas de publicidad. Método: este artículo hace uso de bases de datos como Scopus, Google Scholar, Index-K como fuentes de información para guiar la investigación del uso de las redes sociales. Mediante estadísticas y artículos determinamos los principales aspectos que guían el comportamiento y el uso de las diferentes plataformas de redes sociales en los distintos grupos de edad. Resultados: Este trabajo muestra que dependiendo del grupo de edad el uso de las redes sociales es diferente; los usuarios más jóvenes prefieren las plataformas donde pueden compartir videos o imágenes. Conclusiones: A medida que las personas crecen, las personas se sienten más atraídas por plataformas como Facebook, donde pueden encontrar interacción social, información y pueden compartir diferentes tipos de contenido. Limitación: Este artículo está enfocado a personas que viven en Arlington, una pequeña ciudad en el estado de Virginia. La información encontrada puede ser una base para analizar el comportamiento de los usuarios en diferentes plataformas. &nbsp

An Assessment in the Heat Gain and Loss Through Opaque Elements in Commercial Buildings in Brazil

This paper presents an analysis of the energy performance of commercial buildings in Brazil based on the influence of the thermal transmittance of the external walls and roof. Several combinations were simulated taking into account different input data such as the internal load density, window to wall ratio, solar absorptance and other parameters to evaluate their influence on the annual energy consumption. The sampling techniques are based on the application of the Latin Hipercube method to generate samples, which considers the interaction of two or more parameters for the same case. The influence of different components on the annual heating and cooling load was also investigated through the heat balance method in order to verify the feasibility of analyzing the heat gain and loss through the opaque elements. The analysis was performed using the EnergyPlus program and weather files related to three cities in Brazil (Florianópolis, Curitiba and Salvador)

Red Dyes from West to East in Medieval Europe: From Portuguese Manuscript Illuminations to Romanian Textiles

Red is the color par excellence, its symbolism being linked with protection and magic through its primary attributes, fire and blood. It was the predominant color from the earliest times, certainly during the Greek and Roman periods and into Medieval Europe, until blue became a competitor around the 13th century. Mineral pigments, like iron oxides, were the first red sources, used to draw lines, dots, or spots on cave walls or stones. Later, other mineral red pigments were also exploited: Cinnabar, natural mercury sulfide, since the Neolithic, and realgar, arsenic trisulfide, in Ancient Egypt. Scientific investigation revealed that, although inorganic pigments were mainly used in painting, iron oxides and cinnabar were also the first available sources for coloring textiles. Plant dyes have been known since the Neolithic, exploited by people living in climatically mild areas rich in vegetation. Their use is strongly connected with two other fundamental textile processes: Spinning and weaving. Scholarly literature indicates Egyptian privet (henna, Lawsonia inermis) as the oldest red vegetal source used. Although widely known as a source of brown, the dried leaves, when powdered and treated with lime water, yield an intense orange red, which is efficient for dyeing the body — skin and hair — and textiles of animal origin. Madder (Rubia tinctorum or relatives) was the first dye to be reported from archaeological European Bronze and Iron Ages textiles preserved in the Hallstatt salt mines, Scandinavian bog sites, and other European burials. Apart from madder, the most widely appreciated red dye sources in the European Classical period were kermes (Kermes vermilio and K. ilicis), purple (species of sea snails from the Muricidae family), and extracts of red tree resins, as dragon’s blood (e.g. Dracaena draco, Dracaena cinnabari, and Daemonorops draco). These sources were used for textile dyeing and as organic pigments in paintings

Analysis of Digoxin and Metildigoxin in Whole Blood Using Solid-Phase Extraction and Liquid Chromatography Tandem Mass Spectrometry

A simple and rapid UPLC/MS/MS method has been developed and validated for the analysis of digoxin and metildigoxin in whole blood. Samples were prepared by SPE extraction with Oasis HLB columns. Separation was achieved with an ACQUITY UPLC HSS T3 column (2.1 × 100; 1.8 μm), at 35°C. The mobile phase consisted of acetonitrile (70%) and ammonium formate 5 mM (30%). Total run time was 1.5 min operating at isocratic mode with a flow rate of 0.3 mL/min. Mass spectrometry detection was performed by positive mode electrospray, on the ammonium adducts with two transitions for each analyte and one for the IS (d3-digoxin). The method proved to be specific and linear over the range (0.3–10) ng/mL. This technique also showed high sensitivity with a 0.09 ng/mL LOD and a 0.28 ng/mL LOQ, for both substances. Percentage recovery ranged from 83 to 100% for digoxin and from 62 to 94% for metildigoxin. The intra- and interday precision CV were ≤10%