New Wind in Old Sails: Novel Applications of Triphos-based Transition Metal Complexes as Homogeneous Catalysts for Small Molecules and Renewables Activation

Recent developments in the coordination chemistry and applications of Ru-triphos [triphos = 1,1,1-tris-(diphenylphosphinomethyl)ethane] systems are reviewed, highlighting their role as active and selective homogenous catalysts for small molecule activation, biomass conversions and in carbon dioxide utilization-related processes

A recommender system for behavioral change in 60-70-year-old adults

Early old age (60-70 years old) is a particular period of life when possible habit modifications may occur, often related to job retirement. While taking up a more sedentary lifestyle may be pernicious for health, changing behavior by introducing simple exercises within daily life routines can effectively prevent age-related functional decline. This article presents the Profiling Tool, a system that provides 60-70-year-old adults with personalized recommendations to integrate simple activities, promoting balance, strength, and physical activity into their daily life. Its first implementation has been designed on information from literature, data from previously available longitudinal datasets, and experts' opinions. It has been deployed within a randomized controlled trial. Strategies for its update are based on model-based reinforcement learning approaches.publishedVersionPeer reviewe

Diagnostic and Therapeutic Challenges of Malignant Pleural Mesothelioma

Malignant pleural mesothelioma is a rare cancer characterized by a very poor prognosis. Exposure to asbestos is the leading cause of malignant pleural mesothelioma. The preinvasive lesions, the mesothelial hyperplasia and its possible evolution are the focus of the majority of the studies aiming to identify the treatable phase of the disease. The role of BAP-1 and MTAP in the diagnosis of mesothelioma in situ and in the prognosis of malignant pleural mesothelioma is the main topic of recent studies. The management of preinvasive lesions in mesothelioma is still unclear and many aspects are the subject of debate. The diagnosis, the disease staging and the accurate, comprehensive assessment of patients are three key instants for an appropriate management of patients/the disease

THE EMPIRICAL DIMENSIONS OF ANALYTIC PROCESS: AN EMPIRICAL INVESTIGATION

The aim of this study was to empirically identify the dimensions of the therapist’s, patient’s and interaction contributions to the analytic process. We performed an Exploratory Factor Analysis of patients’ contributions, therapists’ contributions and interaction dimensions, as assessed with the Analytic Process Scales (APS; Waldron et al., 2004) and Dynamic Interaction Scales (DIS; Waldron, Gazzillo et al., 2013) of 540 sessions from 27 analytic therapies. The EFA identified three dimensions of patients’ contributions (the patient reflects about her/his life and problems; the patient reflects about her/his relationship with the therapist; the patient dynamic competence); these factors explain 84.9% of the variance of patients’ contributions. We identified also three dimensions of the therapists’ contributions (therapist relational attitude, therapist dynamic competence, therapist confrontativeness), which explain 65.7% of the variance of therapists’ contributions; and one overall interaction factor explaining 59% of the variance of the APS and DIS interaction scales. Generalized Estimating Equations and partial correlation analyses enabled us to explore the interactions among these dimensions during the therapeutic process. In particular, we explored how the patient dynamic competence and the therapist dynamic competence and relational attitude contribute to the interaction, and how the interaction may strengthen the patient dynamic competence, i.e. the patients’ ability to participate productively to the analytic process and to oscillate between experiencing and reflecting on their experiences

Classical interventions or relational approach? The first results of an in-progress empirical research on process and outcome of psychoanalyses.

Risultati parziali di una ricerca su processo ed esito di trattamenti psicoanalitici a lungo termin

Fostering the capacity of the patients to oscillate between experiencing and reflecting: an empirical study on process and outcome of psychoanalyses

Aim: The aim of this study is to identify the technical and relation factors which contribute to the good outcome of psychoanalysis. Method: In order to accomplish this goal, we have assessed 600 sessions from 30 psychoanalytic treatments audio recorded an transcripted, 8 sessions from the first month, 4 from the middle of the therapy and 8 from the last month. The 8 sessions from the first month and the 8 sessions from the last month were assessed with the Shedler-Westen assessment Procedure-200 (SWAP-200; Shedler, Westen, 1999a, b), the Global Assessment of Functioning Scale (GAF, APA, 2000); the first 8 sessions were assessed also with the Helping Alliance Rating Scales (HAR; Luborsky, Crits-Cristoph, Alexander, Margolis, & Cohen, 1983) and all the sessions were assessed with the Analytic Process Scales (APS; Waldron et al., 2004) and the Dynamic Interaction Scales (DIS; Waldron et al., 2013). Results: The comparison between good and poor outcome treatments pointed out the relevance of both classical analytic interventions (clarification and interpretation of defenses, conflicts and emotional and behavioral patterns) and relational factors (straightforwardness, warmly and attuned responsiveness, empathy). Moreover, our data pointed out the correlation of the capacity of the patients to oscillate between experiencing and reflecting of the patients on their experience with the level of their Personality Health Index (PHI; Waldron et al., 2011).Finally, we explored what are the technical and relational elements of therapist communication that foster the patients capacity to oscillate between experiencing and reflecting. Discussion: The clinical and training implications of these data will be discussed

Classical interventions or relational approach? The first results of an in-progress empirical research on process and outcome of psychoanalyses.

Risultati parziali di una ricerca su processo ed esito di trattamenti psicoanalitici a lungo termin

APS research study: risultati preliminari e implicazioni cliniche

none7sinoneGazzillo, F., Waldron, S., Genova, F., Angeloni, F., Ristucci, C., Mellone, V., Lingiardi, V.Gazzillo, F., Waldron, S., Genova, F., Angeloni, F., Ristucci, C., Mellone, V., Lingiardi, V

A recommender system for behavioral change in 60-70-year-old adults

Early old age (60-70 yearsold) is a particular period of life when possible habit modifications may occur, often related to job retirement. While taking up a more sedentary lifestyle may be pernicious for health, changing behavior by introducing simple exercises within daily life routines can effectively prevent age-related functional decline. This article presents the Profiling Tool, a system that provides 60-70-year-old adults with personalized recommendations to integrate simple activities, promoting balance, strength, and physical activity into their daily life. Its first implementation has been designed on information from literature, data from previously available longitudinal datasets, and experts' opinions. It has been deployed within a randomized controlled trial. Strategies for its update are based on model-based reinforcement learning approaches

Iron(II) Complexes of the Linear <i>rac-</i>Tetraphos‑1 Ligand as Efficient Homogeneous Catalysts for Sodium Bicarbonate Hydrogenation and Formic Acid Dehydrogenation

The linear tetraphosphine 1,1,4,7,10,10-hexaphenyl-1,4,7,10-tetraphosphadecane (tetraphos-1, P4) was used as its <i>rac</i> and <i>meso</i> isomers for the synthesis of both molecularly defined and in situ formed Fe­(II) complexes. These were used as precatalysts for sodium bicarbonate hydrogenation to formate and formic acid dehydrogenation to hydrogen and carbon dioxide with moderate to good activities in comparison to those for literature systems based on Fe. Mechanistic details of the reaction pathways were obtained by NMR and HPNMR experiments, highlighting the role of the Fe­(II) monohydrido complex [FeH­(<i>rac</i>-P4)]⁺ as a key intermediate. X-ray crystal structures of different complexes bearing <i>rac</i>-P4 were also obtained and are described herein