Catalogue of Neotropical Curtonotidae (Diptera, Ephydroidea)

As espécies Neotropicais de Curtonotidae são atualizadas e catalogadas. Um total de 33 nomes específicos é listado, incluindo dois táxons fósseis e um nomem dubium. Nomes válidos e inválidos e sinônimos são apresentados, totalizando 45 nomes. Referências bibliográficas são dadas para todas as espécies listadas, incluindo informações sobre o nome, autor, ano de publicação, número de página, espécie-tipo e localidade-tipo. Lectótipo e paralectótipos são designados para Curtonotum punctithorax (Fischer, 1933).The Neotropical species of Curtonotidae are updated and catalogued. A total of 33 species names are listed, including two fossil taxa and one nomem dubium. Valid and invalid names and synonyms are presented, totaling 45 names. Bibliographic references are given to all listed species, including information about name, author, year of publication, page number, type species and type locality. Lectotype and paralectotypes are designated to Curtonotum punctithorax (Fischer, 1933). Curtonotum simplex Schiner, 1868 stat. rev. is recognized as a valid name

Catalogue of Syringogastridae (Diptera, Diopsoidea)

The catalogue of the Syringogastridae is updated, including now 21 extant species and two fossil records, all belonging to the genus Syringogaster Cresson. References to all known bibliography are given, totaling 27 records. A full list of the type-series and distribution records are also presented

A phylogeny of Carrerapyrgota Aczél (Diptera, Pyrgotidae)

Carrerapyrgota Aczél, 1956 is a Neotropical Diptera genus within Pyrgotidae. Currently, the genus comprise four species: C. miliaria Aczél, 1956 (type species), C. personata (Lutz & Lima, 1918), C. aczeli Mello, Lamas & Rafael, 2010, and C. bernardii Mello, Lamas & Rafael, 2010. This study investigates the phylogenetic relationships among Carrerapyrgota species, aiming to establish their monophyly as a genus. To achieve this, we conducted phylogenetic analyses based on 22 external morphological characters of adults, emploing the principle of parsimony. Analyses using both equal and implied character weighting support the monophyly of the genus, based on the following apomorphies: absence of the postscutellum, R₂₊₃ with spurious apical vein, lower calypter with a longitudinal row of bristles, and the presence of a posterior longitudinal groove on the female fore femur. The species C. aczeli, C. bernardii, and C. miliaria form a monophyletic group, supported by the synapomorphic condition of a spot on the forehead. Within this group, C. bernardii and C. miliaria are sister species, sharing the synapomorphic condition of a less sclerotized M vein, after dm-cu compared to the anterior region, as well as the homoplastic condition of a spot on the median occipital sclerite. This phylogenetic analysis reaffirms the synonymy proposed by Bernardi (1990), which treats Anapyrgota Steyskal, 1967, as a junior synonym of Carrerapyrgota. The evolutionary relationship among the species of the genus is represented as (C. personata (C. aczeli (C. bernardii, C. miliaria))). Furthermore, this study includes an updated distributional map for the genus, featuring the first record of Pyrgotinae in the Andean region

Review of Ants (Hymenoptera: Formicidae) as bioindicators in the Brazilian Savanna

The Brazilian Savanna is threatened mainly by the expansion of agriculture and livestock. Regarding environmental problems, habitat loss in the biome and the need to verify studies on ants as bioindicators, the goal of this paper was to carry out a bibliographic review of the literature about ants as bioindicators in this biome from the last 30 years. We searched papers about ants as bioindicators in the Brazilian Savanna from the last 30 years, refining the search between the years 1986 to 2016 and we analyzed 16 papers about ants as bioindicators. Monitoring studies focusing on ants as bioindicators in the Brazilian Savanna started in 1992 and increased since 2002. The results obtained in the studies presented changes in the species richness and composition in relation to potential bioindication. In general, 167 species are defined as bioindicators of the Brazilian Savanna and are related to specific habitats. We verified that most studies were done Minas Gerais state. We noted that the absence of rigorous analysis damaged the results of the studies, as well as the knowledge of ant fauna biology for correct attribution of indication characteristics of preserved or degraded areas

Catalogue of Pyrgotidae (Diptera: Tephritoidea) from Chile

A catalogue of the Pyrgotidae (Diptera) from Chile is provided. All valid names are presented, comprising three species in two genera for the country. All references known to us from the taxonomic and biological literature, to the included names, are provided, including information about name, author, year of publication, page number, type species, type locality, distribution, and references

Immunotherapy in patients with advanced non-small cell lung cancer lacking driver mutations and future perspectives

From a complete literature review, we were able to present in this paper what is most current in the treatment with immunotherapy for advanced non-small cell lung cancer (NSCLC). Especially the use of immunotherapy, particularly inhibitors of PD-1 (programmed cell death protein 1), PDL-1 (programmed cell death protein ligand 1), and CTLA-4 (cytotoxic T-lymphocyte antigen 4). Since 2015, these drugs have transformed the treatment of advanced NSCLC lacking driver mutations, evolving from second-line therapy to first-line, with excellent results. The arrival of new checkpoint inhibitors such as cemiplimab and the use of checkpoint inhibitors earlier in the therapy of advanced and metastatic cancers has been making the future prospects for treating NSCLC lacking driver mutations more favorable and optimistic. In addition, for those patients who have low PDL-1 positivity tumors, the combination of cytotoxic chemotherapy, VEGF inhibitor, and immunotherapy have shown an important improvement in global survival and progression free survival regardless the PDL-1 status. We also explored the effectiveness of adding radiotherapy to immunotherapy and the most current results about this combination. One concern that cannot be overlooked is the safety profile of immune checkpoint inhibitors (ICI) and the most common toxicities are described throughout this paper as well as tumor resistance to ICI.info:eu-repo/semantics/publishedVersio

Checklist of the dipterofauna (Insecta) from Roraima, Brazil, with special reference to the Brazilian Ecological Station of Maracá

Roraima is a Brazilian state located in the northern portion of the Amazon basin, with few studies regarding its biodiversity. The Ecological Station of Maracá (Brazil, state of Roraima) harbors the third largest Brazilian pluvial island and is composed of a transitional landscape of savanna and Amazon rainforest components. Despite its ecological importance and strategic localization, few studies covered the dipterofauna of this locality. An updated checklist addressing 41 families of true flies (Diptera) occurring in Roraima is presented based on the literature and the specimens collected during a field expedition that occurred in 2015. This checklist brings several improvements such as new records of 165 taxa to the state of Roraima, 29 taxa to Brazil, and 259 morphotypes, mostly likely representing undescribed species

FAMILY CURTONOTIDAE

Mello, Ramon Luciano (2016): FAMILY CURTONOTIDAE. Zootaxa 4122 (1): 716-718, DOI: 10.11646/zootaxa.4122.1.6

Catalogue of the type material of Neriidae (Diptera, Schizophora) in the collection of the Museum fur Naturkunde Berlin, Germany

The Diptera collection of the Natural History Museum Berlin holds one of the most important collections of Neriidae. In this paper, the type specimens (holotypes, lectotypes, paratypes, paralectotypes, syntypes) of this historical collection are listed. 28 species-group taxa are dealt with. A lectotype designation is made for the species Brachantichir purpusianus Enderlein, 1922 in order to fix the identity of the name. Holotypes are recognized by monotypy of the species Chaetomeristes bullatus Enderlein, 1922; Chaetomeristes peruanus Enderlein, 1922; Derocephalus angusticollis Enderlein, 1922; Glyphidops limbatus Enderlein, 1922; Longina abdominalis Wiedemann, 1830; Loxozus clavicornis Enderlein, 1922; Oncopsia mexicana Enderlein, 1922; Paranerius fibulatus Enderlein, 1922; Telostylinus dahli Enderlein, 1922; Telostylus latibrachium Enderlein, 1922; and Telostylinus luridus Enderlein, 1922. Syntypes are labelled and listed for Brachantichir robusta Enderlein, 1922; Nerius terebratus Enderlein, 1922; Odontoloxozus punctulatus Enderlein, 1922; Telostylinus apicalis Enderlein, 1922; Telostylinus obscuratus Enderlein, 1922; and Telostylinus ornatipennis Enderlein, 1922. The account concludes with geographic and taxonomic summaries; an appendix listing the abbreviations, localities, and collectors cited in the text; and a bibliography. ((c) 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)Deutscher Akademischer Austausch Dienst (DAAD)Deutscher Akademischer Austausch Dienst (DAAD)Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq) [141656/2007-7]Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq

Sistematic of Pyrgotidae of the New World (Diptera, Schizophora)

Neste trabalho, é apresentada a revisão taxonômica dos Pyrgotidae pertencentes à fauna do Novo Mundo, atualmente composta por 66 nomes válidos de espécies distribuídas em 15 gêneros. A revisão taxonômica resultou na descrição de dois novos gêneros e de duas novas espécies e na sinonímia de quatro gêneros e 18 espécies e uma espécie foi revalidada. De acordo com esses resultados a fauna de Pyrgotidae do Novo Mundo possui 51 espécies válidas dispostas em 12 gêneros. Análises filogenéticas foram processadas com o intuito de testar o monofiletismo dos gêneros e estabelecer o relacionamento entre suas espécies, além de testar o desempenho dos caracteres contínuos na filogenia de Pyrgotidae. Com este propósito foram levantados 54 caracteres morfológicos dos adultos, sendo 14 contínuos e 40 discretos. Os caracteres contínuos e discretos foram analisados separadamente e em evidência total. As análises em que se utilizaram apenas caracteres discretos e as que utilizaram os caracteres em evidência total, resultaram em topologias muito semelhantes entre si, divergindo apenas nas posições entre três terminais. Na topologia obtida em evidência total, o suporte dos ramos aumentou na maioria dos ramos o que demonstra que os caracteres contínuos são filogeneticamente informativos para serem utilizados em Pyrgotidae.This work presents a taxonomic revision of New World Pyrgotidae, currently composed of 66 valid species names distributed in 15 genera. The taxonomic revision resulted in the description of two new genera and two species, synonymy of four genera and 18 species and revalidation of 1 species. According to these results, the Pyrgotidae of the New World contains 51 valid species arranged in 12 genera. Phylogenetic analyses were conducted to test the monophyly of the genera, establish the relationships among their species, and test the performance of continuous characters in the phylogeny of Pyrgotidae. Fifty-four morphological characters of adults were coded and divided as: 14 continuous and 40 discrete. Continuous and discrete characters were analyzed separately and under total evidence. The analyses using only discrete characters and in total evidence each resulted in one tree, which were very similar, diverging only in the positions of three terminals. In the tree obtained using total evidence, the branch support increased in more branches, which demonstrates that continuous characters are phylogenetically informative for use in analyses of the Pyrgotidae