Barriers for developing more robust organic arable farming systems in practice

There is a gap between the scientific idea of robust and economically viable organic arable farming systems with optimized crop rotations for nutrient and pest management and how these systems look like in practice. In order to explore this gap, we visited and interviewed ten organic arable farms in Denmark. Our main findings are: 1) Organic arable farming operates in a very dynamic and changing environment in terms of prizing and market opportunities, and the main focus of the farm managements was the coping strategy within this changing environment; 2) The farming systems were continuously changing and developing, buying and renting more land, changing manure agreements and other forms of cooperation and arrangements; 3) Short term profit was paid much more attention than more theoretical expectation on long term profit or opportunities in relation to optimizing the production system. This again seems logical in relation to the very dynamic world that the farmers have to operate within; 4) Most of the farmers do not see their farm as a coherent system but as a coordination of a series of separate operations, which means that most decisions are taken with specific reference to the individual field in at the present situation without considering the long-term effects. Management focus is thus much more on solving problems as they are occurring, by adjusting their practice, than it is on developing a robust system preventing problems to occur. This partial focus is also strongly supported by the way in which extension services mostly operate

Picture card tool for holistic planning in organic plant production

Presentation of a new tool for strategic farm planning and improving farm management. The tool is based on picture cards and is meant as an important help for the advisory service for organic farmers. The tool can help the farm manager to raise the yields and the economic performance in organic plant production

Incompatibility between fertility building measures and the management of perennial weeds in organic cropping systems

Fertility building measures are important components in improving the productivity of organic cropping systems without livestock. However, some measures seem to be incompatible with the control of perennial weeds that can have adverse effects such as significant weed competition. The influence of fertility building measures (N2-fixing crops in the crop sequence, cover crops and manuring) and the abundance of perennial weeds were studied in a long-term crop rotation experiment at two locations in Denmark. The aim was to gain insight into the factors that influence the growth of perennial weed species occurring in mixed stands. Data were obtained from three cycles of four-year arable crop rotations comprising various cash crops in rotations with and without annual whole-year grass-clover as green manure and subjected to four treatment combinations: with and without animal manure and with and without cover crops. Severe outbreaks of perennial weed problems did not occur at the location that had the highest soil fertility, whereas the other site demonstrated dynamic growth of Cirsium arvense and Elytrigia repens. Grain legumes tended to promote the growth of C. arvense, while manuring was neutral to C. arvense but beneficial to E. repens. Cover crops assisted the growth of E. repens since prolonged mechanical interventions were not possible. Compatibility was only achieved with grass-clover and C. arvense, meaning that green manure crops suitable for cutting and mulching could offer an important management option against C. arvense but not against E. repens

Muligheder og barrierer for implementering af principper for robuste og højtydende planteavlssædskifter i praksis – Grundlagsrapport for barrierer undersøgelsen

I det økologiske forskningsprojekt, HighCrop, under GUDP - går økologiske planteavlere, konsulenter og forskere sammen om at finde ud af, hvordan planteavlen på de økologiske planteavlsbedrifter kan udvikles til at være mere robuste og bæredygtige. Et af indsatsområderne er, via interviewbesøg med 10 økologiske planteavlere, at afdække, hvordan den faglige viden når ud til landmændene og hvilke rådgivningstiltag og redskaber der bedst muligt kan understøtte denne videndeling. Denne rapport beskriver det teoretiske og metodiske grundlag for denne barriere undersøgels

Numerical renormalization group of vortex aggregation in 2D decaying turbulence: the role of three-body interactions

In this paper, we introduce a numerical renormalization group procedure which permits long-time simulations of vortex dynamics and coalescence in a 2D turbulent decaying fluid. The number of vortices decreases as $N\sim t^{-\xi}$, with $\xi\approx 1$ instead of the value $\xi=4/3$ predicted by a na\"{\i}ve kinetic theory. For short time, we find an effective exponent $\xi\approx 0.7$ consistent with previous simulations and experiments. We show that the mean square displacement of surviving vortices grows as $\sim t^{1+\xi/2}$. Introducing effective dynamics for two-body and three-body collisions, we justify that only the latter become relevant at small vortex area coverage. A kinetic theory consistent with this mechanism leads to $\xi=1$. We find that the theoretical relations between kinetic parameters are all in good agreement with experiments.Comment: 23 RevTex pages including 7 EPS figures. Submitted to Phys. Rev. E (Some typos corrected; see also cond-mat/9911032

The Mre11-Rad50-Nbs1 complex mediates activation of TopBP1 by ATM

The activation of ATR-ATRIP in response to double-stranded DNA breaks (DSBs) depends upon ATM in human cells and Xenopus egg extracts. One important aspect of this dependency involves regulation of TopBP1 by ATM. In Xenopus egg extracts, ATM associates with TopBP1 and thereupon phosphorylates it on S1131. This phosphorylation enhances the capacity of TopBP1 to activate the ATR-ATRIP complex. We show that TopBP1 also interacts with the Mre11-Rad50-Nbs1 (MRN) complex in egg extracts in a checkpoint-regulated manner. This interaction involves the Nbs1 subunit of the complex. ATM can no longer interact with TopBP1 in Nbs1-depleted egg extracts, which suggests that the MRN complex helps to bridge ATM and TopBP1 together. The association between TopBP1 and Nbs1 involves the first pair of BRCT repeats in TopBP1. In addition, the two tandem BRCT repeats of Nbs1 are required for this binding. Functional studies with mutated forms of TopBP1 and Nbs1 suggested that the BRCT-dependent association of these proteins is critical for a normal checkpoint response to DSBs. These findings suggest that the MRN complex is a crucial mediator in the process whereby ATM promotes the TopBP1-dependent activation of ATR-ATRIP in response to DSBs

A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease

Existing knowledge of genetic variants affecting risk of coronary artery disease (CAD) is largely based on genome-wide association studies (GWAS) analysis of common SNPs. Leveraging phased haplotypes from the 1000 Genomes Project, we report a GWAS meta-analysis of 185 thousand CAD cases and controls, interrogating 6.7 million common (MAF>0.05) as well as 2.7 million low frequency (0.005<MAF<0.05) variants. In addition to confirmation of most known CAD loci, we identified 10 novel loci, eight additive and two recessive, that contain candidate genes that newly implicate biological processes in vessel walls. We observed intra-locus allelic heterogeneity but little evidence of low frequency variants with larger effects and no evidence of synthetic association. Our analysis provides a comprehensive survey of the fine genetic architecture of CAD showing that genetic susceptibility to this common disease is largely determined by common SNPs of small effect siz

Common Variants at 10 Genomic Loci Influence Hemoglobin A(1C) Levels via Glycemic and Nonglycemic Pathways

OBJECTIVE Glycated hemoglobin (HbA1c), used to monitor and diagnose diabetes, is influenced by average glycemia over a 2- to 3-month period. Genetic factors affecting expression, turnover, and abnormal glycation of hemoglobin could also be associated with increased levels of HbA1c. We aimed to identify such genetic factors and investigate the extent to which they influence diabetes classification based on HbA1c levels. RESEARCH DESIGN AND METHODS We studied associations with HbA1c in up to 46,368 nondiabetic adults of European descent from 23 genome-wide association studies (GWAS) and 8 cohorts with de novo genotyped single nucleotide polymorphisms (SNPs). We combined studies using inverse-variance meta-analysis and tested mediation by glycemia using conditional analyses. We estimated the global effect of HbA1c loci using a multilocus risk score, and used net reclassification to estimate genetic effects on diabetes screening. RESULTS Ten loci reached genome-wide significant association with HbA1c, including six new loci near FN3K (lead SNP/P value, rs1046896/P = 1.6 × 10−26), HFE (rs1800562/P = 2.6 × 10−20), TMPRSS6 (rs855791/P = 2.7 × 10−14), ANK1 (rs4737009/P = 6.1 × 10−12), SPTA1 (rs2779116/P = 2.8 × 10−9) and ATP11A/TUBGCP3 (rs7998202/P = 5.2 × 10−9), and four known HbA1c loci: HK1 (rs16926246/P = 3.1 × 10−54), MTNR1B (rs1387153/P = 4.0 × 10−11), GCK (rs1799884/P = 1.5 × 10−20) and G6PC2/ABCB11 (rs552976/P = 8.2 × 10−18). We show that associations with HbA1c are partly a function of hyperglycemia associated with 3 of the 10 loci (GCK, G6PC2 and MTNR1B). The seven nonglycemic loci accounted for a 0.19 (% HbA1c) difference between the extreme 10% tails of the risk score, and would reclassify ∼2% of a general white population screened for diabetes with HbA1c. CONCLUSIONS GWAS identified 10 genetic loci reproducibly associated with HbA1c. Six are novel and seven map to loci where rarer variants cause hereditary anemias and iron storage disorders. Common variants at these loci likely influence HbA1c levels via erythrocyte biology, and confer a small but detectable reclassification of diabetes diagnosis by HbA1c

Quasi-stationary States of Two-Dimensional Electron Plasma Trapped in Magnetic Field

We have performed numerical simulations on a pure electron plasma system under a strong magnetic field, in order to examine quasi-stationary states that the system eventually evolves into. We use ring states as the initial states, changing the width, and find that the system evolves into a vortex crystal state from a thinner-ring state while a state with a single-peaked density distribution is obtained from a thicker-ring initial state. For those quasi-stationary states, density distribution and macroscopic observables are defined on the basis of a coarse-grained density field. We compare our results with experiments and some statistical theories, which include the Gibbs-Boltzmann statistics, Tsallis statistics, the fluid entropy theory, and the minimum enstrophy state. From some of those initial states, we obtain the quasi-stationary states which are close to the minimum enstrophy state, but we also find that the quasi-stationary states depend upon initial states, even if the initial states have the same energy and angular momentum, which means the ergodicity does not hold.Comment: 9 pages, 7 figure