TOI-1055 b: Neptunian planet characterised with HARPS, TESS, and CHEOPS

Context. TOI-1055 is a Sun-like star known to host a transiting Neptune-sized planet on a 17.5-day orbit (TOI-1055 b). Radial velocity (RV) analyses carried out by two independent groups using nearly the same set of HARPS spectra have provided measurements of planetary masses that differ by ∼2σ. Aims. Our aim in this work is to solve the inconsistency in the published planetary masses by significantly extending the set of HARPS RV measurements and employing a new analysis tool that is able to account and correct for stellar activity. Our further aim was to improve the precision on measurements of the planetary radius by observing two transits of the planet with the CHEOPS space telescope. Methods. We fit a skew normal function to each cross correlation function extracted from the HARPS spectra to obtain RV measurements and hyperparameters to be used for the detrending. We evaluated the correlation changes of the hyperparameters along the RV time series using the breakpoint technique. We performed a joint photometric and RV analysis using a Markov chain Monte Carlo scheme to simultaneously detrend the light curves and the RV time series. Results. We firmly detected the Keplerian signal of TOI-1055 b, deriving a planetary mass of Mb = 20.4-2.5+2.6 MO (∼12%). This value is in agreement with one of the two estimates in the literature, but it is significantly more precise. Thanks to the TESS transit light curves combined with exquisite CHEOPS photometry, we also derived a planetary radius of Rb = 3.490-0.064+0.070 RO (∼1.9%). Our mass and radius measurements imply a mean density of ρb = 2.65-0.35+0.37 g cm-3 (∼14%). We further inferred the planetary structure and found that TOI-1055 b is very likely to host a substantial gas envelope with a mass of 0.41-0.20+0.34 MO and a thickness of 1.05-0.29+0.30 RO. Conclusions. Our RV extraction combined with the breakpoint technique has played a key role in the optimal removal of stellar activity from the HARPS time series, enabling us to solve the tension in the planetary mass values published so far for TOI-1055 b

Evaluaci\uf3n del cumplimiento de los deberes formales contenidos en la Ley de Impuesto Sobre la Renta del A\uf1o 2001 y disposiciones del C\uf3digo Org\ue1nico Tributario vigente de la normativa de precios de transferencia, por parte de los contribuyentes especiales de la Regi\uf3n Centroccidental domiciliados en Barquisimeto, Estado Lara

Este trabajo de investigaci\uf3n descriptivo y de campo tiene como objetivo general la evaluaci\uf3n del cumplimiento de los Deberes Formales contenidos en la Ley de Impuesto sobre la Renta del a\uf1o 2001 y disposiciones del C\uf3digo Org\ue1nico Tributario vigente, de la normativa de precios de transferencia, por parte de los Contribuyentes Especiales de la Regi\uf3n Centroccidental domiciliados en Barquisimeto Estado Lara. Para ello, se ha consultado la bibliograf\ueda relacionada con el tema, considerando los antecedentes, marco conceptual, bases jur\ueddicas del tema. As\ued mismo este trabajo pone en evidencia la necesidad de establecer los procedimientos de control fiscal y auditor\ueda fiscal de los precios de transferencia pero principalmente la divulgaci\uf3n de esta normativa por parte de la Administraci\uf3n Tributaria. Para esta investigaci\uf3n se aplicaron a un grupo de contribuyentes cuestionarios con preguntas abiertas y cerradas, as\ued como tambi\ue9n una entrevista estructurada al Jefe de Divisi\uf3n de Contribuyentes Especiales de la Regi\uf3n, lo que permiti\uf3 identificar los rasgos distintivos de la situaci\uf3n. Los datos recolectados se analizaron de manera cuantitativa y cualitativa y se contrataron con los fundamentos te\uf3ricos y normativos que regulan esta parte del impuesto, obteniendo como resultado un desinformaci\uf3n general por parte de los contribuyentes de esta materia, y que lleva consigo a recurrir a fuentes externas para la capacitaci\uf3n de los profesionales independientes y dependientes para evitar ser sancionado por el ente regulador de los impuestos venezolanos. De este modo se llegan a unas conclusiones principalmente dirigidas al llamado a la Administraci\uf3n Tributaria para divulgar o publicitar esta nueva normativa y disminuir el grado de evasi\uf3n por parte de sus administrados, planteando recomendaciones b\ue1sicas como lo es la coordinaci\uf3n de acciones fiscalizadoras, aunado a una campa\uf1a que lleve a los contribuyentes a formularse interrogantes en esta materia y elevar el n\ufamero de consultas que motiven a cumplir con las obligaciones referentes a esta normativa

Dosimetry of 51MnCl2 and 52MnCl2 for PET application

Manganese has been so far mainly used for in-vivo animal studies of tissue anatomy of liver, kidneys, heart and pancreas, as well as to monitor cellular activity, cytoarchitecture and neuronal tract tracing in the brain by using the so-called Manganese-Enhanced Magnetic Resonance Imaging (MEMRI)-based techniques. However, the large amount of manganese necessary for MEMRI may induce neurotoxic effects that result in manganism, a neurological syndrome similar to Parkinson\u2019s disease. The much higher sensitivity of positron emission tomography (PET) over MRI enables, instead, the use of non-toxic trace level concentrations of Mn. The radioisotopes 52Mn (t1/2= 5.591 d, \u3b2+= 29.4%, E(\u3b2+)avg= 241.6 keV) and 51Mn (t1/2= 45.59 min, \u3b2+=97.1%, E(\u3b2+)avg = 970.2 keV) have already been used for preclinical PET imaging in the past, mainly administered in free ionic form as MnCl2 1-2. However, internal radiation dose assessment due to the administration of 52MnCl2 to humans is still missing, while only one study has been reported for 51MnCl2 dosimetry calculations2. The aim of this work is to fill this gap by assessing the radiation effective dose (ED) of 51MnCl2 and 52MnCl2

Carora cattle shows high variability at \u3b1Sl-casein

The objective of this study was to analyze the genetic variability of milk proteins of the Carora, a short-horned Bos taurus cattle breed in Venezuela and in other Southern American countries that is primarily used for milk production. A total of 184 individual milk samples were collected from Carora cattle in 5 herds in Venezuela. The milk protein genes \u3b1s1-casein (CN) (CSN1S1), \u3b2-CN (CSN2), \u3ba-CN (CSN3), and \u3b2-lactoglobulin (LGB) were typed at the protein level by isoelectrofocusing. It was necessary to further analyze CSNlSl at the DNA level by a PCR-based method to distinguish CSN1S1*G from B. Increased variation was found in particular at the CSN1S1 gene, where 4 variants were identified. The predominant variant was CSN1S1*B (frequency = 0.8). The second most common CSN1S1 variant was CSN1S1*G (0.101), followed by CSN1S1*C (0.082). Moreover, a new isoelectrofocusing pattern was identified, which may result from a novel CSN1S1 variant, named CSN1S1*I, migrating at an intermediate position between CSN1S1*B and CSN1S1*C. Six cows carried the variant at the heterozygous condition. For the other loci, predominance of CSN2*A 2 (0.764), CSN3*B (0.609), and LGB*B (0.592) was observed. Haplotype frequencies (AF) at the CSN1S1-CSN2-CSN3 complex were also estimated by taking association into account. Only 7 haplotypes showed AF values >0.05, accounting for a cumulative frequency of 0.944. The predominant haplotype was B-A2-B (frequency = 0.418), followed by B-A 2-A (0.213). The occurrence of the G variant is at a rather high frequency, which is of interest for selection within the Carora breed because of the negative association of this variant with the synthesis of the specific protein. From a cheese-making point of view, this variant is associated with improved milk-clotting parameters but is negatively associated with cheese ripening. Thus, milk protein typing should be routinely carried out in the breed, with particular emphasis on using a DNA test to detect the CSN1S*G variant. The CSN1S*G allele is likely to have descended from the Brown Swiss, which contributed to the Carora breed and also carries this allele

Dosimetric analysis of the contribution of Radionuclides Coproduced through natV(p,x)47Sc reaction route in Cyclotron Irradiation

Scandium presents different radionuclides with good imaging and therapeutic properties for the development of theranostic radiopharmaceuticals. In particular, 47Sc (t1/2= 3.35 d) has suitable features both for SPECT imaging, thanks to the 159 keV \u3b3-ray emission, and for treatment of small-size tumours, thanks to the intense \u3b2 12 emission (mean \u3b2 12 energy: 162.0 keV). Its efficacy has been demonstrated at preclinical stage, but its low availability has however limited the application of 47Sc-based radiopharmaceuticals to the clinic. Among the different proposed production routes, the natV(p,x)47Sc nuclear reaction is of particular interest, due to the low-cost and easy availability of the target material, as well as the widespread availability of medium-energy cyclotrons. However, the nuclear cross section of this reaction is quite low and small amounts of Sc radioactive contaminants are co-produced. The aim of this work is to evaluate the contribution of Sc-contaminants to the patient radiation dose

New Records Of Ferns From Chiapas, Mexico

Volume: 102Start Page: 233End Page: 23