Erol Pekcan'ın anısına düzenlenen konser bugün CRR'de:Türk cazında üç kuşak bir arada

Taha Toros Arşivi, Dosya No: 120-Erol Pekca

The evaluation of staphylococci strains isolated from nasal and bone cultures in patients with chronic osteomyelitis

Objectives: In this study, it was aimed to determine theprevalence of nasal carriage of S. aureus in chronic osteomyelitis,assessed trends in methicillin resistance withtime, and evaluated the bone and nasal cultures in staphylococcalchronic osteomyelitis.Materials and methods: Bone and nasal cultures wereperformed intra-operative and pre-operatively from 43patients with chronic osteomyelitis. Inoculation was performedon 5% sheep blood and eosine-methylen-blueagar. The samples were incubated at 37°C for 24 hours.Catalase and coagulase tests were performed on Grampositive coccus strains. Antimicrobial susceptibilities of allS. aureus strains were evaluated by disc diffusion methodaccording to CLSI for oxacillin and other antibiotics.Results: In this study pre-operative nasal cultures andintra-operative bone cultures obtained between May 2005and September 2006 were evaluated retrospectively. Ofthe 43 nasal cultures, 31 (72%) yielded staphylococcalstrain, of these 18 (58%) were S. aureus. Of the 18 S.aureus strains, 13 (72.2%) have methicilline resistance.On the other hand, of the 43 bone cultures, 29 (67.4%)yielded staphylococci strain, of these 23 (79.3%) were S.aureus. Of the 23 S. aureus strains, 52.1% have methicillineresistance. Overall the similarity rate of staphylococcalstrains was 38% (11/29), while considering the statusof strains resistant to antibiotics; this ratio was 24% (7/29).Conclusions: Nasal S. aureus carriage rate (58%) in patientswith chronic osteomyelitis was higher than the communityand the other patient groups. However, the surveillancecultures can give knowledge about the causativepathogen of 25% of the culture negative cases.Key words: Chronic osteomyelitis, nasal carriage, Staphylococcusaureus, bone cultur

Doçentlik süreci ve bazı akademik kadrolardaki düzenlemelere yönelik öğretim elemanlarının görüşlerinin değerlendirilmesi

Bu araştırmanın amacı 7100 Sayılı Yükseköğretim Kanunu ile bazı kanun ve kanun hükmünde kararnamelerde değişiklik yapılması sonucunda resmi gazetede yayınlanan yeni doçentlik kriterlerine yönelik akademisyenlerin görüşlerini belirlemektir. Araştırma nitel yönteme dayalı yürütülmüştür. Bu kapsamda çalışmaya Fırat Üniversitesi, Bitlis Eren Üniversitesi, Afyon Kocatepe Üniversitesi, İnönü Üniversitesi ve Erzincan Üniversitesindeki 244 akademisyen katılmıştır. İlgili yasa düzenlemesine dayanarak araştırmacılar tarafından veri toplamak amacıyla yapılandırılmış ve yarı yapılandırılmış görüşme formu kullanılmıştır. Veriler içerik analizi ve betimsel analiz kullanılarak çözümlenmiştir. Ayrıca bazı özgün ifadelere yer verilmiştir. Sonuç olarak doçentlik ile ilgili yasal düzenlemeye yönelik görüşlerin oldukça dağınık olduğu, birçok akademisyenin görüş belirtmekten kaçındığı gözlenmektedir. Araştırma bulguları yabancı dil puanı açısından yasal düzenleme ile örtüşmemektedir. Akademisyenler doçentlik sözlü ve atama süreçlerinin üniversiteler tarafından yürütülmesine yönelik bazı endişeler taşımaktadırlar. Katılımcılar doçentlik ile ilgili bazı düzenlemelerin bu süreci suiistimale açık hale getirdiğini ifade etmişlerdir. Gerek bilimsel çalışmalar ve gerekse atama süreçlerinde objektif olmayan durumların söz konusu olabileceği görülmüştür. Ancak edinilen nihai intiba yasal düzenlemenin eksik olduğu yönündedir. Doçentlik ve profesörlük kadro tahsisleri şartlar oluştuğunda merkezi bir biçimde yapılması önerilmektedir. Yabancı dil becerileri akademisyenler açısından olmazsa olmaz durumundadır. Ancak mevcut sınavlar yabancı dil becerilerini bütün yönleriyle test etmekten uzaktır. Yabancı dil sınavlarının tüm becerileri içine alacak şekilde değiştirilmesi gerekmektedir. Bunun yanında bu süreçte teşvik edici, kolaylaştırıcı bazı eylem planlarına ihtiyaç olduğu da ortadadır. Üniversiteler akademisyenlerinin test çözerek, kitap okuyarak dil becerilerini geliştirmeleri yerine onlara pratik yapabilecekleri imkânlar sağlamalıdırlar

Necrotizing Fasciitis Resulting from Human Bite: A Case Report of Disease Caused by Sphingomonas paucimobilis

Bites of human origin mostly occur in males between the ages of 20-30 years, and are seen especially on the arms, fingers and headneck regions. These bites can cause complications ranging from slight injuries to serious infections. Infections can originate from the biter’s oral cavity and victims’s skin flora. In this report, a case of necrotizing fasciitis due to human bite caused by Sphingomonas paucimobilis is presented. S. paucimobilis should be kept in mind as an infectious agent in humans, and the infections should be treated according to the sensitivity test results

Investigation of Nasal Staphylococcus Aureus Carriage in Intensive Care Unit and Operating Room Staff

Aim: In this study, we aimed to investigate the prevalence of nasal carriage of Staphylococcus aureus in our hospital staff, and antibiotic susceptibility of these strains to methicillin and some other antibiotics. Methods: In this study, involving personnel working in operating room, neonatal and intensive care units of our hospital, nose cavity swab samples were taken from 81 subjects using cotton swabs soaked into serum physiologic. Single colony inoculation was performed on 5% sheep blood agar. The samples were incubated at 37oC for 24 hours. The Catalase and coagulase tests were performed on the strains which showed gram-positive cocci. We evaluated antimicrobial susceptibility of all S. aureus strains to oxacillin and several other antibiotics by disc diffusion method according to the Clinical and Laboratory Standards Institute (CLSI) recommendations.. Results: Nasal S. aureus carrier was detected in 21 subjects (25.9%). Among all S. aureus isolated from nasal area, nine (11.1%) were methicillin-resistance and 12 (14.8%) were methicillin-susceptible S. aureus. When the occupation was considered, the carriage rates were 20.8% among doctors, 25% among auxiliary health-care workers and 29.7% among health-care workers other than doctors. There was no significant difference in carriage rate between these groups (p=0.239). The isolated strains showed no resistance to mupirocin and teicoplanin. Intranasal administration of mupirocin to all carriers for five days resulted in elimination of staphylococci with a success rate of 100%. Conclusion: According to these results, we assume that the nasal carriage of methicillin-resistant S. aureus is not an important issue in our hospital. However, it was concluded that topical mupirocin is an effective agent to be used securely in the elimination of S. aureus colonization in nasal carriers. (The Me di - cal Bul le tin of Ha se ki 2012; 50: 48-52

Stevens-johnson syndrome caused by combined use of lamotrigine and fluoxetine and review of the literature

Geyik, Mehmet Faruk/0000-0002-0906-0902WOS: 000285419600015Stevens-Johnson syndrome (SJS) is a rare, life-threatening acute allergic drug reaction presenting with target lesions and blebs of epidermis. Although a variety of etiologies such as infections and underlying malignancies have been implicated as potential causes of SJS, drugs remain the predominant inciting agent. This report presents a SJS case due to combined use of lamotrigine and fluoxetine. A 41-year-old man was admitted to our clinic with fever, skin eruptions (especially on the face and trunk) and lesions around the mouth. The patient's history revealed lamotrigine and fluoxetine use during the previous three weeks for major depression. Dermatological examination revealed a typical clinical picture of SJS; his psychotropic medications were all stopped. While topical and ocular prednisolone (1mg/kg/day) cares were initiated, steroid dosage was reduced within 15 days. The condition of patient rapidly improved through this treatment. Effective management of SJS begins with prompt recognition of the entity, combined with attention to each of the major organs that may be affected, potential comorbidities and withdrawal of all potentially causative drugs. Clinicians should bear in mind the possibility that drugs with potential risk in developing SJS must be used carefully