A host of factors regulating influenza virus replication.

A new series of genetic screens begins to illuminate the interaction between influenza virus and the infected cell

Smart Vehicle to Grid Interface Project: Electromobility Management System Architecture and Field Test Results

This paper presents and discusses the electromobility management system developed in the context of the SMARTV2G project, enabling the automatic control of plug-in electric vehicles' (PEVs') charging processes. The paper describes the architecture and the software/hardware components of the electromobility management system. The focus is put in particular on the implementation of a centralized demand side management control algorithm, which allows remote real time control of the charging stations in the field, according to preferences and constraints expressed by all the actors involved (in particular the distribution system operator and the PEV users). The results of the field tests are reported and discussed, highlighting critical issues raised from the field experience.Comment: To appear in IEEE International Electric Vehicle Conference (IEEE IEVC 2014

The nature of chlorine-inhibition of photocatalytic degradation of dichloroacetic acid in a TiO2-based microreactor

Photocatalytic degradation of dichloroacetic acid (DCA) was studied in a continuous-flow set-up using a titanium microreactor with an immobilized double-layered TiO2 nanoparticle/nanotube film. Chloride ions, formed during the degradation process, negatively affect the photocatalytic efficiency and at a certain concentration (approximately 0.5 mM) completely stop the reaction in the microreactor. Two proposed mechanisms of inhibition with chloride ions, competitive adsorption and photogenerated-hole scavenging, have been proposed and investigated by adsorption isotherms and electron paramagnetic resonance (EPR) measurements. The results show that chloride ions block the DCA adsorption sites on the titania surface and reduce the amount of adsorbed DCA molecules. The scavenging effect of chloride ions during photocatalysis through the formation of chlorine radicals was not detected.Slovenian Research Agency/P2-0084Slovenian Research Agency/J2-4309Slovene Human Resources Development and Scholarship Fund/Ad Futur

Inside the Aviary

Modularity and movement of energy are two key concepts in the construction of Nikki Mehle\u27s paintings. Painting is an act of both processing and creating reality – the duality of reflection and invention

Reconstruction of the 1918 Influenza Virus: Unexpected Rewards from the Past

The influenza pandemic of 1918–1919 killed approximately 50 million people. The unusually severe morbidity and mortality associated with the pandemic spurred physicians and scientists to isolate the etiologic agent, but the virus was not isolated in 1918. In 1996, it became possible to recover and sequence highly degraded fragments of influenza viral RNA retained in preserved tissues from several 1918 victims. These viral RNA sequences eventually permitted reconstruction of the complete 1918 virus, which has yielded, almost a century after the deaths of its victims, novel insights into influenza virus biology and pathogenesis and has provided important information about how to prevent and control future pandemics

Protecting Patients: A Proposal For Codifying The Reasonable Innovation Rule

Part II of this Comment will examine the history of human experimentation and how the current regime of experimenting developed then explore the gap between experimentation approved by an Institutional Review Board (“IRB”) and FDA oversight. Part III will consider the competing interests of individual patient protection and medical innovation in general and whether informed consent appropriately balances those interests. Part IV will evaluate the inadequacies of current reliance on informed consent by using two case studies, both involving novel microbial procedures, and discuss how codification of the reasonable innovation rule would address those inadequacies. Ultimately, this Comment will argue that the common law reasonable innovation rule must be codified to protect vulnerable patients who are willing to try anything. Current oversight and regulation of physicians who implement novel treatments on a regular basis do not offer enough protection to the desperate patient. It is time for the FDA to intervene in our current “wild west” system where physicians are free to deviate from common practice and implement novel and even dangerous procedures as long as they obtain patients’ informed consent

Interactions in vivo between the Vif protein of HIV-1 and the precursor (Pr55GAG) of the virion nucleocapsid proteins

The abnormality of viral core structure seen in vif-defective HIV-1 grown in PBMCs has suggested a role for Vif in viral morphogenesis. Using an in vivo mammalian two-hybrid assay, the interaction between Vif and the precursor (Pr55GAG) of the virion nucleocapsid proteins has been analysed. This revealed the amino-terminal (aa 1–22) and central (aa 70–100) regions of Vif to be essential for its interaction with Pr55GAG, but deletion of the carboxy-terminal (aa 158–192) region of the protein had only a minor effect on its interaction. Initial deletion studies carried out on Pr55GAG showed that a 35-amino-acid region of the protein bridging the MA(p17)–CA(p24) junction was essential for its ability to interact with Vif. Site-directed mutagenesis of a conserved tryptophan (Trp21) near the amino terminus of Vif showed it to be important for the interaction with Pr55GAG. By contrast, mutagenesis of the highly conserved YLAL residues forming part of the BC-box motif, shown to be important in Vif promoting degradation of APOBEC3G/3F, had little or no effect on the Vif–Pr55GAG interaction

Currency fundamentals, implied volatility, and FX investment strategies as NOK determinants

Masteroppgave(MSc) in Master of Science in Business, Finance - Handelshøyskolen BI, 2019We study which factors determine the Norwegian krone at the weekly frequency. We show the existence of a relation between the EURNOK depreciation rate and changes in oil prices, implied volatility indices, and the excess returns on carry trade and value FX investment strategies. In particular, our findings suggest that the Norwegian krone is exposed to global risks proxied by the implied volatility indices and carry trade factor, is not exposed to the momentum factor, and has a risk discount as proxied by the value factor

The Boltzmann-Gibbs distribution of money

To delo obravnava uporabo metod fizike na statističnih modelih za porazdelitev denarja, kot primer pristopa ekonofizike. V zaprtem gospodarskem sistemu se denar ohranja. Po analogiji z energijo mora ravnotežje verjetnostne porazdelitve denarja slediti Boltzmann-Gibbsovem zakonu, pri čemer je efektivna temperatura enaka povprečnemu znesku denarja na agenta. Numerične simulacije kažejo, da to drži vsaj takrat, ko je število agentov in povprečni znesek denarja na agenta velik. Glavni cilj diplomskega dela je ta rezultat dokazati.This paper is concerned with the application of the methods of physics to statistical models for money distribution as an example of the approach of econophysics. In a closed economic system, money is conserved. By analogy with energy, the equilibrium probability distribution of money must follow the exponential Boltzmann-Gibbs law characterized by an effective temperature equal to the average amount of money per economic agent. Numerical simulations suggest that at least when the number of agents and the average amount of money per agent are large, this is true. The main objective of this paper is to give a rigorous proof of this result

Newdelhijski virus kodravosti listov paradižnika

Status: Newdelhijski virus kodravosti listov paradižnika je virus iz rodu Begomovirus. Uvrščen je v Prilogo II/B Uredbe 2019/2072/EU