CONSTRAINT ROBUST PORTFOLIO SELECTION BY MULTIOBJECTIVE EVOLUTIONARY GENETIC ALGORITHM

The problem of portfolio selection is a very challenging problem in computational finance and has received a lot of attention in last few decades. Selecting an asset and optimal weighting of it from a set of available assets is a critical issue for which the decision maker takes several aspects into consideration. Different constraints like cardinality constraints, minimum buy in thresholds and maximum limit constraint are associated with assets selection. Financial returns associated are often strongly non-Gaussian in character, and exhibit multivariate outliers. Taking these constraints into consideration and with the presence of these outliers we consider a multi-objective problem where the percentage of each available asset is so selected that the total profit of the portfolio is maximized while total risk is minimized. Nondominated Sorting Genetic Algorithm-II is used for solving this multiobjective portfolio selection problem. Performance of the proposed algorithm is carried out by performing different numerical experiments using real-world data

Electronic and Band Structure Calculation of Wurtzite CdS Using GGA and GGA+U functionals

The wurtzite (wz) structure of CdS is analyzed using density functional theory within the generalized gradient approximation (GGA) and Hubbard correction (GGA+U). The total energy convergence evaluation is carried out concerning energy cut-off (ecutwfc) and k-point sampling. The geometry optimization of wz-CdS is calculated using the total energy and force minimization process, which is based on the Broyden Fletcher Goldfarb Shanno (BFGS) optimization algorithm. Bulk modulus and lattice parameters are estimated to ensure accuracy of the calculations. The electronic band structure, density of states (DOS), and projected density of states (PDOS) of wz-CdS are analyzed. The band structure calculation shows CdS as direct band gap semiconductor. The electronic correlation in CdS is altered by varying U-parameters of valence orbitals of Cd and S. The alteration of electronic correlation results in convergence of the band gap to the experimental value 2.4 eV. The alteration of U-parameter affects substantially the density of states near the band edges

Intern’s knowledge of clinical pharmacology and therapeutics at Puducherry: a cross-sectional study

Background: Internship is the intermediate period between under-graduation and general practice. The dexterity of health professional relies upon prescribing practices. Clinical pharmacology and therapeutics (CPT) is a crucial discipline for interns to acquire safe and rational prescription of drugs. Cultivating sound knowledge about CPT during under graduation is, henceforth, mandatory.Aims and objectives:To assess whether the undergraduate CPT teaching and internship training had prepared interns adequately for safe and rational prescription.To assess the awareness and reporting of adverse drug reaction (ADR).Methods: 110 interns were enrolled after obtaining informed written consent. A structured questionnaire was given to them including basic demographic information, undergraduate CPT teaching, experience of ADR and any deficiency in the under-graduate CPT teaching.Results: Response rate was 91 % in which 53 were males and 47 females. 81 considered themselves aware of CPT. 56% & 57% interns were able to prescribe drug safely and rationally respectively. Without supervision, they were confident to prescribe antacids (93%), vitamins and minerals (90%), NSAIDS (85%), antihistamines (82%), antibiotics (75%), antiemetics (62%) and antiasthmatics (52%). Only 22% had reported ADR and opined that it could lead to hospitalization (51%), prolonged hospital stay (33%), morbidity (16%) and death (21%). According to interns, the topics where more emphasis needed were ADR, dosage calculation, pediatric and emergency medicine and therapeutic drug monitoring during undergraduate CPT teaching.Conclusion: CPT teaching should be improved at undergraduate level for safe and rational prescribing including ADR monitoring, ADR reporting and dosage calculation

Attribute Based Secured and Efficient Cloud Storage Middleware for Mobile Cloud Computing using PDP

Today handheld devices are playing more vital roles in the people�s daily lives with the fast development of wireless technology. All these devices use Internet for fetching & accessing services. Many current applications are being deployed on Cloud to save hardware & software cost. Mobile cloud has become remarkable cloud service model; in which, mobile devices are used as the information collecting and processing nodes for the cloud infrastructure. Cloud has become the pervasive digital platform for many network applications in their quest to provide a single unified digital platform. In this paper, we present insignificant Cloud-based storage framework. This framework will provide an easy-to-use file navigation service for attribute-based fill querying. Simultaneously, it incorporates an effective structure for users to verify their data integrity, which can relieve much load from mobile devices. Experimental simulations show that the proposed framework is effective to provide flexible data sharing in mobile computing environments

Simulation of Fingering Phenomena in Fluid Flow through Fracture Porous Media with Inclination and Gravitational Effect

Here we have studied the fingering phenomena in fluid flow through fracture porous media with inclination and gravitational effect and investigate the applicability of Adomian decomposition method to the nonlinear partial differential equation arising in this phenomena and prove the convergence of Adomian decomposition scheme, which leads to an abstract result and an analytical approximate solution to the equation. Finally developed a simulation result of saturation of wetting phase with and without considering the inclination effect for some interesting choices of parametric data value and studied the recovery rate of the oil reservoir with dimensionless time

Simulation of Imbibition Phenomena in Fluid Flow through Fractured Heterogeneous Porous Media with Different Porous Materials

In this paper, the counter – current imbibition phenomenon in a fractured heterogeneous porous media is studied with the consideration of different types of porous materials like volcanic sand and fine sand and Adomian decomposition method is applied to find the saturation of wetting phase and the recovery rate of the reservoir. A simulation result is developed to study the saturation of wetting phase in volcanic as well as in fine sand with the recovery rate of the oil reservoir with the choices of some interesting parametric value. This problem has a great importance in the oil recovery process

Synthesis dependent characteristics of Sr1-xMnxTiO3 (x=0.03, 0.05, 0.07 and 0.09)

Sr1-xMnxTiO3 (where x = 0.03, 0.05, 0.07 and 0.09) was synthesized via different routes that include solid-state, oxalate precipitation and freeze drying. In oxalate precipitation technique, compositions corresponding to 3 and 5 mol % doping of Mn were monophasic whereas the higher compositions revealed the presence of the secondary phases such as MnO, Mn3O4 etc., as confirmed by high resolution X-ray diffraction (XRD) studies. The decomposition behavior of the precursors prepared using oxalate precipitation method corresponding to the above mentioned compositions was studied. Nanopowders of compositions pertaining to 5 to 9 mol % of Mn doping were obtained using freeze-drying technique. The average crystallite size of these nanopowders was found to be in the 35 to 65 nm range. The microstructural studies carried out on the sintered ceramics, fabricated using powders synthesized by different routes established the fine grained nature (< 1 microm) of the one obtained by freeze drying method. Raman scattering studies were carried out in order to complement the observations made from XRD regarding the phase purity. The dielectric properties of the ceramics obtained by different synthesis routes were studied in the 80 - 300 K temperature range at 100 kHz and the effect of grain size has been discussed.Comment: 38 pages, 4 tables, 13 figure

Chlorpromazine induced ocular myasthenia gravis

Drug induced bilateral ptosis is a very rare adverse drug reaction. Here we report a case of ten year old male child with chlorpromazine induced bilateral ptosis due to ocular myasthenia

Identification of a suitable clustering method and allocation strategy for core set development in salt stress tolerant rice (Oryza sativa) germplasm

Preserving genetic diversity in repository of germplasm is essential for crop breeding programs. However, maintenance and protection of all the germplasms in gene bank is difficult due to its voluminous size. Hence the development of core set with minimum number of germplasm representing maximum genetic diversity of the population has become an alternative. From the available clustering methods and allocation strategies, identifying a suitable combination is essential for the development of species-specific core set. In the present study, data on 219 salt stress tolerant rice (Oryza sativa L.) germplasm accessions with 14 phenotypic traits and 2915 genome wide Single Nucleotide Polymorphisms (SNPs) is considered to identify a suitable combination of clustering method and allocation strategy for core set development. Eight different combinations consisting of two clustering methods, viz. Ward’s and UPGMA along with four different allocation strategies, viz. L, D, LD and NY allocation with three level of sampling intensities (20%, 25% and 30%) have been tried. Based on the study carried out during 2013-14 at Indian Agricultural Statistics Research Institute, New Delhi, it is concluded that the Ward’s clustering method with NY allocation, irrespective of sampling intensity, is suitable for developing core set with maximum diversity