Cambio de actitud y comunicación persuasiva: claves para comprender los procesos de captación y conversión a sectas

Referencia de la publicación original: Carmona Gallego, A., Marco Macarro, M.J., Paz Rodríguez, J.I., & Sánchez Medina, J.A. (1989). Cambio de actitud y comunicación persuasiva: claves para comprender los procesos de captación y conversión a sectas. Apuntes de Psicología, 28-29, 33-37.En este trabajo se considera a las sectas como un problema de salud pública. Para comprender esta idea es necesario romper con la noción clásica de que su peligrosidad viene dada por su ideología. El problema radica más bien en su organización y en las técnicas que emplean. Vistas desde esta perspectiva son fácilmente abordables por la psicología, ya que ésta posee desarrollos teóricos que nos permiten su estudio

sRNAbench and sRNAtoolbox 2022 update: accurate miRNA and sncRNA profiling for model and non-model organisms

European Union [765492 to M.H.]; Spanish Government [AGL2017-88702-C2-2-R to M.H.]; Chair 'Doctors Galera-Requena in cancer stem cell research' (to J.A.M.); Tromsoforskningsstiftelse (TFS) [20 SG BF 'MIRevolution' to B.F.]; Stichting Cancer Center Amsterdam [CCA2021-9-77 to C.G]; TKI-Health Holland ['AQrate' project to C.G. and M.P.]. This publication is part of a project that has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No. 765492.The NCBI Sequence Read Archive currently hosts microRNA sequencing data for over 800 different species, evidencing the existence of a broad taxonomic distribution in the field of small RNA research. Simultaneously, the number of samples per miRNA-seq study continues to increase resulting in a vast amount of data that requires accurate, fast and user-friendly analysis methods. Since the previous release of sRNAtoolbox in 2019, 55 000 sRNAbench jobs have been submitted which has motivated many improvements in its usability and the scope of the underlying annotation database. With this update, users can upload an unlimited number of samples or import them from Google Drive, Dropbox or URLs. Micro- and small RNA profiling can now be carried out using high-confidence Metazoan and plant specific databases, MirGeneDB and PmiREN respectively, together with genome assemblies and libraries from 441 Ensembl species. The new results page includes straightforward sample annotation to allow downstream differential expression analysis with sRNAde. Unassigned reads can also be explored by means of a new tool that performsmapping to microbial references, which can reveal contamination events or biologically meaningful findings as we describe in the example. sRNAtoolbox is available at: https://arn.ugr.es/srnatoolbox/.European Commission 765492Spanish GovernmentEuropean Commission AGL2017-88702-C2-2-RChair 'Doctors Galera-Requena in cancer stem cell research'Stichting Cancer Center Amsterdam CCA2021-9-77Tromsoforskningsstiftelse (TFS) ['MIRevolution'] 20 SG BFTKI-Health Holland ['AQrate' project

Informe GEM Provincia de Sevilla 2019-2020

El estudio y la investigación sobre la incidencia de los procesos emprendedores en la provincia de Sevilla continúa siendo una prioridad para la Diputación de Sevilla, a través de Prodetur, que desarrolla de esta forma uno de sus principales puntos de su objeto y finalidad social. Tras los resultados del primer informe emitido por la red de investigadores del GEM la pasada anualidad, continuamos apoyando esta importante labor que permite detectar y valorar la actualidad de la actividad emprendedora en Sevilla y su comparativa a nivel autonómico y estatal. El documento que se presenta contiene estudios sobre los principales aspectos del emprendimiento en la provincia de Sevilla, abarcando líneas de investigación tales como actividades, oportunidades, capacidad de creación de empresas, obstáculos, facilidades, o recomendaciones, todo ello situado en el entorno territorial de influencia. El análisis de la situación de partida permite analizar los resultados y potenciar la cultura innovadora y emprendedora, imprescindibles para garantizar el avance social y económico en nuestro territorio. Este año, los informes sobre temas monográficos tales como emprendimiento y género, emprendimiento rural, emprendimiento corporativo y otros se han visto condicionados en gran medida por la situación creada por el COVID19 hasta la fecha. Ante la grave crisis económica y productiva que la pandemia ha provocado es necesario profundizar en el estudio de la situación a corto plazo y colaborar con medidas reparadoras, entre las cuales, Prodetur ha desarrollado varias iniciativas urgentes para paliar en lo posible las consecuencias socioeconómicas que nos han sobrevenido, y que han supuesto un duro golpe a la dinámica empresarial y emprendedora.Universidad Pablo de Olavid

Informe GEM Provincia de Sevilla 2020-2021

El Informe GEM (Global Entrepreneurship Monitor) de la Provincia de Sevilla 2020-2021 ha sido realizado por un grupo de investigadores de la Universidad Pablo de Olavide y la Universidad de Sevilla. Desde GEM se elaboran anualmente informes de ámbito global, nacional, regional y local, gracias a una red de equipos de investigación en los países que participan en el observatorio. La metodología común que se sigue en todos estos ámbitos, permite la obtención de indicadores homogéneos sobre la actividad emprendedora y, por tanto, la comparación del fenómeno entre diferentes territorios y el análisis de su evolución a lo largo del tiempo.Universidad Pablo de Olavide. Departamento de Organización de Empresas y Marketin

Informe GEM Provincia de Sevilla 2021-2022

El Informe GEM (Global Entrepreneurship Monitor) de la Provincia de Sevilla 2021-2022 ha sido realizado por un grupo de investigadores de la Universidad Pablo de Olavide y la Universidad de Sevilla. Desde GEM se elaboran anualmente informes de ámbito global, nacional, regional y local, gracias a una red de equipos de investigación en los países que participan en el observatorio. La metodología común que se sigue en todos estos ámbitos, permite la obtención de indicadores homogéneos sobre la actividad emprendedora y, por tanto, la comparación del fenómeno entre diferentes territorios y el análisis de su evolución a lo largo del tiempo.Universidad Pablo de Olavide. Departamento de Organización de Empresas y Marketin

sRNAbench and sRNAtoolbox 2022 update: accurate miRNA and sncRNA profiling for model and non-model organisms

The NCBI Sequence Read Archive currently hosts microRNA sequencing data for over 800 different species, evidencing the existence of a broad taxonomic distribution in the field of small RNA research. Simultaneously, the number of samples per miRNA-seq study continues to increase resulting in a vast amount of data that requires accurate, fast and user-friendly analysis methods. Since the previous release of sRNAtoolbox in 2019, 55 000 sRNAbench jobs have been submitted which has motivated many improvements in its usability and the scope of the underlying annotation database. With this update, users can upload an unlimited number of samples or import them from Google Drive, Dropbox or URLs. Micro- and small RNA profiling can now be carried out using high-confidence Metazoan and plant specific databases, MirGeneDB and PmiREN respectively, together with genome assemblies and libraries from 441 Ensembl species. The new results page includes straightforward sample annotation to allow downstream differential expression analysis with sRNAde. Unassigned reads can also be explored by means of a new tool that performs mapping to microbial references, which can reveal contamination events or biologically meaningful findings as we describe in the example. sRNAtoolbox is available at: https://arn.ugr.es/srnatoolbox/</a

Common Variation in the PIN1 Locus Increases the Genetic Risk to Suffer from Sertoli Cell-Only Syndrome

We aimed to analyze the role of the common genetic variants located in the PIN1 locus, a relevant prolyl isomerase required to control the proliferation of spermatogonial stem cells and the integrity of the blood–testis barrier, in the genetic risk of developing male infertility due to a severe spermatogenic failure (SPGF). Genotyping was performed using TaqMan genotyping assays for three PIN1 taggers (rs2287839, rs2233678 and rs62105751). The study cohort included 715 males diagnosed with SPGF and classified as suffering from non-obstructive azoospermia (NOA, n = 505) or severe oligospermia (SO, n = 210), and 1058 controls from the Iberian Peninsula. The allelic frequency differences between cases and controls were analyzed by the means of logistic regression models. A subtype specific genetic association with the subset of NOA patients classified as suffering from the Sertoli cell-only (SCO) syndrome was observed with the minor alleles showing strong risk effects for this subset (ORaddrs2287839 = 1.85 (1.17–2.93), ORaddrs2233678 = 1.62 (1.11–2.36), ORaddrs62105751 = 1.43 (1.06–1.93)). The causal variants were predicted to affect the binding of key transcription factors and to produce an altered PIN1 gene expression and isoform balance. In conclusion, common non-coding single-nucleotide polymorphisms located in PIN1 increase the genetic risk to develop SCO.Plan Andaluz de Investigacion, Desarrollo e Innovacion (PAIDI 2020) PY20_00212 P20_00583Spanish Ministry of Economy and Competitiveness through the Spanish National Plan for Scientific and Technical Research and Innovation SAF2016-78722-R PID2020-120157RB-I00Proyectos I + D + i del Programa Operativo FEDER 2020 B-CTS-584-UGR20 B-CTS-260-UGR20Spanish Government RYC-2014-16458Spanish Ministry of Economy and Competitiveness through the "Juan de la Cierva Incorporacion" program (MCIN/AEI) IJC2018038026-IEuropean CommissionMCIN/AEIFSE "El FSE invierte en tu futuro" FPU20/02926 BES-2017-081222Portuguese Foundation for Science and Technology (FCT) - European Social Funds (COMPETE-FEDER) Portuguese Foundation for Science and Technology IF/01262/2014FCT from the Portuguese State Budget of the Ministry for Science, Technology and High Education SFRH/BPD/120777/2016European Social Fund through the Programa Operacional do Capital HumanoPortuguese Foundation for Science and Technology European Commission UID/BIM/00009/2013 UIDB/UIDP/00009/2020Instituto de Salud Carlos III (FEDER funds/European Regional Development Fund (ERDF)-a way to build Europe) DTS18/00101Generalitat de Catalunya 2017SGR191SNS-Dpt. Salut Generalitat de Catalunya CES09/020 MCIN/AEI BES-2017-081222 PEstC/SAU/LA0003/2013 POCI-01-0145-FEDER-00727

CIBERER : Spanish national network for research on rare diseases: A highly productive collaborative initiative

Altres ajuts: Instituto de Salud Carlos III (ISCIII); Ministerio de Ciencia e Innovación.CIBER (Center for Biomedical Network Research; Centro de Investigación Biomédica En Red) is a public national consortium created in 2006 under the umbrella of the Spanish National Institute of Health Carlos III (ISCIII). This innovative research structure comprises 11 different specific areas dedicated to the main public health priorities in the National Health System. CIBERER, the thematic area of CIBER focused on rare diseases (RDs) currently consists of 75 research groups belonging to universities, research centers, and hospitals of the entire country. CIBERER's mission is to be a center prioritizing and favoring collaboration and cooperation between biomedical and clinical research groups, with special emphasis on the aspects of genetic, molecular, biochemical, and cellular research of RDs. This research is the basis for providing new tools for the diagnosis and therapy of low-prevalence diseases, in line with the International Rare Diseases Research Consortium (IRDiRC) objectives, thus favoring translational research between the scientific environment of the laboratory and the clinical setting of health centers. In this article, we intend to review CIBERER's 15-year journey and summarize the main results obtained in terms of internationalization, scientific production, contributions toward the discovery of new therapies and novel genes associated to diseases, cooperation with patients' associations and many other topics related to RD research