326 research outputs found

    Perceptions of Educational Leadership Faculty Regarding Open Access Publishing

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    There is a dearth of research on the perceptions of faculty members in educational leadership regarding open access publications. This reality may exist because of a lack of funding for educational leadership research, financial obstacles, tenure demands, or reputation concerns. It may be that there are simply fewer established open access publishers with reputable impact factors to encourage publication by members in the field. The current study seeks to answer the following question: “What are the perceptions of educational leadership faculty members in UCEA about open access publishing?” The results are based on responses from 180 faculty members in the field of educational leadership

    Creating the essential links for educating the evidence-based medical practitioner of the 21st century

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    A new postgraduate Medical (MBBS) program at the University of Queensland has been the catalyst for the development of a range of University of Queensland (UQ) Cybrary initiatives, in areas of information resources, services and support. Over the past seven years the UQ Cybrary has successfully integrated library services into the problem-based learning and the e-learning environment of the MBBS Program. Information and communications technology developments have been harnessed by the Cybrary to support the needs of the Program which are dispersed throughout the vast state of Queensland. In particular, there has been a focus on using information and communications technology (ICT) to provide efficient and equitable access for all those involved with UQ city and rural health education. The Cybrary has risen to the challenge of providing information services and resources to support evidence-based practice (EBP) and lifelong learning, ultimately contributing towards achieving an outstanding medical workforce for the 21st Century. This paper will outline how the UQ Cybrary has addressed these issues, particularly in the areas of integration of online materials in the e-learning environment, the development and delivery of tailored information literacy programs and the use of ICT to support access to information and services

    Marshall Space Flight Center Technology Capabilities for Use in Space Situational Awareness Activities

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    Marshall performs research, integrates information, matures technologies, and enhances science to bring together a diverse portfolio of products and services of interest for Space Situational Awareness (SSA) and Space Asset Management (SAM), all of which can be accessed through partnerships with Marshall. Integrated Space Situational Awareness and Asset Management (ISSAAM) is an initiative of NASA's Marshall Space Flight Center to improve space situational awareness and space asset management through technical innovation, collaboration, and cooperation with U.S. Government agencies and the global space community. Marshall Space Flight Center provides solutions for complex issues with in-depth capabilities, a broad range of experience, and expertise unique in the world, and all available in one convenient location. NASA has longstanding guidelines that are used to assess space objects. Specifically, Marshall Space Flight Center has the capabilities, facilities and expertise to address the challenges that space objects, such as near-Earth objects (NEO) or Orbital Debris pose. ISSAAM's three pronged approach brings together vital information and in-depth tools working simultaneously toward examining the complex problems encountered in space situational awareness. Marshall's role in managing, understanding and planning includes many projects grouped under each prong area: Database/Analyses/Visualization; Detection/Tracking/ Mitigation/Removal. These are not limited to those listed below

    Archaeological Survey of Proposed Houston Arboretum & Nature Center Improvements, Harris County, Texas

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    On behalf of Design Workshop, Inc. and the Houston Arboretum & Nature Center (HANC), SWCA Environmental Consultants (SWCA) conducted an intensive archaeological survey of the proposed HANC improvements in Harris County, Texas. The portion of the HANC to be affected by the proposed improvements consists of an approximately 55-acre area (project area) located in the northern third of the overall 155-acre HANC. Archaeological investigations were conducted in compliance with the Antiquities Code of Texas under Antiquities Permit No. 7592 and with guidelines set forth by the Texas Historical Commission (THC). The background literature review revealed that no cultural resources surveys had been conducted within the boundaries of the project area, although 12 cultural resources surveys had been conducted within 1 mile of the project area. In addition, five archaeological sites (41HR614, 41HR617, 41HR791, 41HR885, and 41HR1158), five historic structures, and two cemeteries were found to be located within a 1-mile radius of the boundary of the HANC. Site 41HR614, representing the intact remains of a WWI training facility, Camp Logan, has been recorded as a State Antiquities Landmark, and site 41HR617, a prehistoric lithic scatter has been recorded as potentially eligible for State Antiquities Landmark designation. One historic structure, the Meachum and Mellinger House, has been listed on the National Register of Historic Places (NRHP). During the field investigation, a team of two archaeologists examined only those portions of the HANC where construction activities were anticipated. In accordance with THC standards, SWCA excavated 59 shovel tests within the project area. One new historic archaeological site (41HR1181), representing an early twentieth-century historic dump, was identified and delineated. A second locus of scattered brick was also identified; however, the locus contained no other artifacts and appeared to be displaced. This locus was recorded as Isolated Find 1. In addition, an SWCA architectural historian completed an architectural evaluation of the Houston Arboretum Visitor Center, a potentially historic structure designed by noted Houston architect Hugo Victor Neuhaus, Jr., that has been significantly modified in the past. SWCA conducted a non-collection survey; therefore, no cultural materials will be curated. The original survey documentation will be curated with the Texas State University Center for Archaeological Studies. In accordance with the Antiquities Code of Texas, SWCA has made a reasonable and good faith effort to identify significant cultural resources within the project area. No properties listed or otherwise eligible for listing in the NRHP, or eligible for official designation as a State Antiquities Landmark, were identified within the project area. Consequently, SWCA recommends no further archaeological investigation, and that the project be allowed to proceed

    Potato Leafhopper Control in South Dakota Alfalfa

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    Potato leafhoppers migrate into South Dakota each year and are capable of causing extensive damage to first-year and established alfalfa stands. This pest is difficult to detect, and it often damages alfalfa before producers are aware of its presence. Potato leafhoppers can be especially damaging to newly seeded alfalfa stands

    Race does not explain genetic heterogeneity in pharmacogenomic pathways

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    Polymorphic alleles in the human genome have been identified as affecting numerous drug responses. Currently, genotyping of all patients before starting a drug regimen is impractical. Since many polymorphisms occur at varying rates in different racial groups, we investigated whether a patient's race could predict presence of drug-relevant genetic variants well enough to be used as a substitute for individual genotyping

    wuHMM: a robust algorithm to detect DNA copy number variation using long oligonucleotide microarray data

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    Copy number variants (CNVs) are currently defined as genomic sequences that are polymorphic in copy number and range in length from 1000 to several million base pairs. Among current array-based CNV detection platforms, long-oligonucleotide arrays promise the highest resolution. However, the performance of currently available analytical tools suffers when applied to these data because of the lower signal:noise ratio inherent in oligonucleotide-based hybridization assays. We have developed wuHMM, an algorithm for mapping CNVs from array comparative genomic hybridization (aCGH) platforms comprised of 385 000 to more than 3 million probes. wuHMM is unique in that it can utilize sequence divergence information to reduce the false positive rate (FPR). We apply wuHMM to 385K-aCGH, 2.1M-aCGH and 3.1M-aCGH experiments comparing the 129X1/SvJ and C57BL/6J inbred mouse genomes. We assess wuHMM's performance on the 385K platform by comparison to the higher resolution platforms and we independently validate 10 CNVs. The method requires no training data and is robust with respect to changes in algorithm parameters. At a FPR of <10%, the algorithm can detect CNVs with five probes on the 385K platform and three on the 2.1M and 3.1M platforms, resulting in effective resolutions of 24 kb, 2–5 kb and 1 kb, respectively

    A population of large neurons in laminae III and IV of the rat spinal cord that have long dorsal dendrites and lack the neurokinin 1 receptor

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    The dorsal horn of the rat spinal cord contains a population of large neurons with cell bodies in laminae III or IV, that express the neurokinin 1 receptor (NK1r) and have long dorsal dendrites that branch extensively within the superficial laminae. In this study, we have identified a separate population of neurons that have similar dendritic morphology, but lack the NK1r. These cells also differ from the NK1r-expressing neurons in that they have significantly fewer contacts from substance P-containing axons and are not retrogradely labelled following injection of tracer into the caudal ventrolateral medulla. We also provide evidence that these cells do not belong to the postsynaptic dorsal column pathway or the spinothalamic tract. It is therefore likely that these cells do not have supraspinal projections. They may provide a route through which information transmitted by C fibres that lack neuropeptides is conveyed to deeper laminae. The present findings demonstrate the need for caution when attempting to classify neurons solely on the basis of somatodendritic morphology

    Key Lessons Learned from Moffitt's Molecular Tumor Board: The Clinical Genomics Action Committee Experience

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    The increasing practicality of genomic sequencing technology has led to its incorporation into routine clinical practice. Successful identification and targeting of driver genomic alterations that provide proliferative and survival advantages to tumor cells have led to approval and ongoing development of several targeted cancer therapies. Within many major cancer centers, molecular tumor boards are constituted to shepherd precision medicine into clinical practice
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