Evaluation of appendicitis risk prediction models in adults with suspected appendicitis

Background Appendicitis is the most common general surgical emergency worldwide, but its diagnosis remains challenging. The aim of this study was to determine whether existing risk prediction models can reliably identify patients presenting to hospital in the UK with acute right iliac fossa (RIF) pain who are at low risk of appendicitis. Methods A systematic search was completed to identify all existing appendicitis risk prediction models. Models were validated using UK data from an international prospective cohort study that captured consecutive patients aged 16–45 years presenting to hospital with acute RIF in March to June 2017. The main outcome was best achievable model specificity (proportion of patients who did not have appendicitis correctly classified as low risk) whilst maintaining a failure rate below 5 per cent (proportion of patients identified as low risk who actually had appendicitis). Results Some 5345 patients across 154 UK hospitals were identified, of which two‐thirds (3613 of 5345, 67·6 per cent) were women. Women were more than twice as likely to undergo surgery with removal of a histologically normal appendix (272 of 964, 28·2 per cent) than men (120 of 993, 12·1 per cent) (relative risk 2·33, 95 per cent c.i. 1·92 to 2·84; P < 0·001). Of 15 validated risk prediction models, the Adult Appendicitis Score performed best (cut‐off score 8 or less, specificity 63·1 per cent, failure rate 3·7 per cent). The Appendicitis Inflammatory Response Score performed best for men (cut‐off score 2 or less, specificity 24·7 per cent, failure rate 2·4 per cent). Conclusion Women in the UK had a disproportionate risk of admission without surgical intervention and had high rates of normal appendicectomy. Risk prediction models to support shared decision‐making by identifying adults in the UK at low risk of appendicitis were identified

Domesticating the Tourist Gaze in Thessaloniki's Prigipos

The article examines how Prigipos, a cafe´ in the northern Greek city of Thessaloniki,communicates Greek cosmological themes through the way it ‘stages’ urban memories.The staging suggests an ‘Oriental’ tourist-like flaˆnerie that matches, and is directed towards the cafe´’s physical and symbolic surroundings (notably, the TurkishConsulate, the adjacent paternal house of Turkey’s first President, Kemal Ataturk, butalso the old part of the city, historically populated by Greek refugees from AnatolianTurkey). My ethnographic eye is examined as constitutive of this flanerie, especially sinceI grew up in Thessaloniki. Through the employment of mixed research tools andmethods, I explore how Prigipos’s spectacular self-presentation replaced old migrantkafeneion culture with new aesthetic fusions to enable its global consumerist mobility. Atthe same time, the article argues that old ethno-national formulas are enmeshed inPrigipos’s design and narratives, endorsing a Thessalonikiote permutation of culture