Seafloor fault ruptures along the North Anatolia Fault in the Marmara Sea, Turkey: Link with the adjacent basin turbidite record

The relation between seafloor fault ruptures and the generation of turbidity currents was investigated to better understand the structural growth of tectonic basins with direct implications for earthquake hazard assessment. This study focuses on the Holocene earthquake record of transtensional basins in the Marmara Sea, Turkey, that are associated with the North Anatolian Fault system. The physical and chemical composition of three 10 m-long cores recovered from the Central Basin was studied at high-resolution and turbidite–homogenite units were identified. Turbidite–homogenite units (T–H units) are complex deposits that consist of a sharp basal contact and multiple fining upward beds of sand to coarse silt, above. All are capped by a 25 cm to 75 cm thick layer of medium to fine silt. A chronology developed from radiocarbon and short-lived radioisotopes allowed the correlation of these T–H units to the historical record of earthquakes that in Turkey goes back 2000 years. We found that the best location to recover the most complete sedimentation record is in the deepest part of a basin or “depocenter” where T–H units constitute ~ 80% of the sediments. A very good correlation was established between T–H units in Central Basin and proximal inferred historic epicentres along the central Marmara segment of the North Anatolia Fault that occurred in 1343, 860, 740, and 557 AD, and two more distal earthquakes that occurred in 268 and 1963 (or possibly1964). These sedimentation events can then be referred to as “seismo-turbidites”. The results when compared to findings from other transform basins in Marmara Sea reveal a very good correlation between T–H units and historic ruptures. Most importantly, there is a strong correlation between the inferred locations of historical earthquakes and the preservation of turbidite–homogenite units in the basin adjacent to the inferred rupture. The 740 AD earthquake correlates with T–H units in Izmit Gulf and Central Basin and could represent a multi-segment rupture of the NAF. Generally, T–H units appear to be clustered through the Holocene sections, suggesting temporal earthquake clustering in the Marmara Sea region. Such clustering may account for the lack of T–H units and hence large ruptures through the Central Basin since 1343

Seafloor fault ruptures along the North Anatolia Fault in the Marmara Sea, Turkey: Link with the adjacent basin turbidite record

The relation between seafloor fault ruptures and the generation of turbidity currents was investigated to better understand the structural growth of tectonic basins with direct implications for earthquake hazard assessment. This study focuses on the Holocene earthquake record of transtensional basins in the Marmara Sea, Turkey, that are associated with the North Anatolian Fault system. The physical and chemical composition of three 10 m-long cores recovered from the Central Basin was studied at high-resolution and turbidite–homogenite units were identified. Turbidite–homogenite units (T–H units) are complex deposits that consist of a sharp basal contact and multiple fining upward beds of sand to coarse silt, above. All are capped by a 25 cm to 75 cm thick layer of medium to fine silt. A chronology developed from radiocarbon and short-lived radioisotopes allowed the correlation of these T–H units to the historical record of earthquakes that in Turkey goes back 2000 years. We found that the best location to recover the most complete sedimentation record is in the deepest part of a basin or “depocenter” where T–H units constitute ~ 80% of the sediments. A very good correlation was established between T–H units in Central Basin and proximal inferred historic epicentres along the central Marmara segment of the North Anatolia Fault that occurred in 1343, 860, 740, and 557 AD, and two more distal earthquakes that occurred in 268 and 1963 (or possibly1964). These sedimentation events can then be referred to as “seismo-turbidites”. The results when compared to findings from other transform basins in Marmara Sea reveal a very good correlation between T–H units and historic ruptures. Most importantly, there is a strong correlation between the inferred locations of historical earthquakes and the preservation of turbidite–homogenite units in the basin adjacent to the inferred rupture. The 740 AD earthquake correlates with T–H units in Izmit Gulf and Central Basin and could represent a multi-segment rupture of the NAF. Generally, T–H units appear to be clustered through the Holocene sections, suggesting temporal earthquake clustering in the Marmara Sea region. Such clustering may account for the lack of T–H units and hence large ruptures through the Central Basin since 1343

The sedimentary imprint of Pleistocene glacio-eustasy: Implications for global correlations of seismic sequences

We evaluate lithofacies, chronology, and seismic sequences from the Canterbury Basin, New Zealand passive continental slope (Integrated Ocean Drilling Program [IODP] Expedition 317 Site U1352 and environs) and compare this with slope sequences from the New Jersey passive margin. Our goal is to understand continental slope sedimentation in response to glacio-eustasy and test the concepts of sequence stratigraphy. High-resolution geochemical elemental and lithostratigraphic analyses were calibrated to a chronology constructed from benthic foramininferal oxygen isotopes for the past ~1.8 m.y. We identify lithofacies successions by their unique geochemical and lithologic signature and correlate them with marine isotope stages (MIS) at Milankovitch 100 k.y. (MIS 1–12) and 41 k.y. (MIS 13–63) periods. Eight seismic sequence boundaries (U13–U19) were identified from high-resolution multichannel seismic data, providing a seismic stratigraphic framework. Except for MIS 1–5 and MIS 54–55, there are 2–16 MIS stages and a comparable number of lithofacies contained within each seismic sequence, indicating that it took one to several glacio-eustatic cycles to build each seismic stratigraphic sequence. These findings support prior results obtained by the Ocean Drilling Program (ODP) Leg 174A on the New Jersey continental slope. On both margins, there is a strong correlation between seismic sequences, lithofacies, and MIS, thus linking them to glacio-eustasy. However, the correlation between MIS and seismic sequences is not one-to-one, and Pleistocene seismic sequences on the two margins are not synchronous. Local conditions, including differences in sedimentation rates and creation of accommodation space, strongly influenced sediment preservation at each location, revealing that high-frequency Pleistocene seismic sequences need not correlate globally

Spatial Variations in a Condensed Interval between Estuarine and Open-Marine Settings: Holocene Hudson River Estuary and Adjacent Continental Shelf

An interval of stratigraphic condensation extending for 300 km from the fluvially dominated Hudson River estuary to the adjacent continental shelf reveals stratal relationships within an unconformity-related depositional sequence that are commonly difficult to resolve in seismic reflection profiles and outcrop. High-resolution side-scan sonar and bathymetry, more than 100 sediment cores ∼2 m long, and radioisotope (14C, 137Cs) age control show that much of the valley was filled by ca. 3 to 1 ka. The present rate of sediment accumulation averages 1 mm/yr, corresponding with a sea-level rise of ∼1.2 mm/yr relative to local bedrock. Condensation is manifested today by sedimentary bypass in most parts of the estuary and by the trapping of available sediment (1.2–5.6 × 105 t/yr [metric tons]) along narrow reaches and primarily in the vicinity of the estuarine turbidity maximum, a part of the estuary located upstream of the salinity intrusion ∼25 km from the mouth (3.0 × 105 t/yr). Shelf condensation is due to sediment starvation. The condensed interval merges updip with a nascent sequence boundary as the estuary reaches its final filling phase and downdip with the sequence boundary that developed at the Last Glacial Maximum. Delta progradation may take place as available shelf accommodation is filled, but such sediments are expected to be removed once sea level begins to fall. This sedimentation pattern, in which a condensed interval merges with different sequence boundaries, is consistent with the stratigraphic record of the Atlantic margin back to the Paleogene and may be typical of sediment-starved margins

Estuarine Processes and Their Stratigraphic Record: Paleosalinity and Sedimentation Changes in the Hudson Estuary (North America)

Paleosalinity estimates and rates of sedimentation inferred from core samples from the Hudson estuary for the interval between 6.4 and 1.3 ka indicate a possible role for the estuarine turbidity maximum (ETM) in influencing patterns of estuarine sedimentation at centennial to millennial time scales. Currently in the estuary, sedimentation is localized via sediment trapping particularly in the vicinity of the ETM, 13–26 km upstream from Battery Park (FBP) at the southern tip of Manhattan, in water depths greater than 4 m, and on the western side of the estuary. Data presented in this paper are from cores located within the segment of the estuary 29–50 km FBP. Age constraints are provided by C-14 dating. Paleoenvironmental interpretations are based upon paleosalinity estimates, grain size variability, and sedimentary structures. Paleosalinity was inferred on the basis of foraminiferal biofacies analysis and a new method for estimating summertime paleosalinity using oxygen isotope measurements in bivalve shell material. The isotopic analysis of a narrow size fraction (1.0–1.7 mm) representing summer growth of a single bivalve species (Gemma gemma) reduces the uncertainty related to annual changes in temperature. Data from ∼45 km FBP indicate a gradual decrease in summertime paleosalinity between 6.4 and 2.0 ka from 25–20‰ to 15–10‰ (the latter is similar to present-day values). These results are consistent with the conclusion of an earlier low-resolution study. Sedimentation rates are generally low and are similar to the rate of sea-level rise in the Hudson River. Lowest sedimentation rates are noted in short (lower than 2 m) cores from north of the Tappan Zee Bridge (40–50 km FBP from 2.4 ka to present); in shallow water (∼2 m at mean low water, core SD-11) ∼45 km FBP; and on the eastern side of the estuary from ∼50 to 29 km FBP. Exceptions are high sedimentation rates (up to four times background) observed in cores from the western flats (SD 30, ∼45 km FBP, 4.9 to 3.4 ka) in water depths of 4 m and from the western part of the main channel (P21.7 core, ∼32 km FBP, greater than 2.3 to ∼1.3 ka). We hypothesize that the observed pattern in sediment accumulation relates to a location for the ETM some 20 km upstream of its present position at 3 ka. Downstream migration of the ETM since 3 ka is ascribed to shoaling of the estuary, effectively squeezing the marine saltwater wedge in the same direction, and off marginal flats into the channel. Such shoaling would have enhanced the role of waves in mixing marine and fresher surface water, and reduced the effect of the ETM in focusing sediment accumulation. The results of this study are consistent with the idea that at any time, estuarine sedimentation is highly localized, suggesting a more complex depositional pattern than previously indicated in estuarine stratigraphic models

Integrative Acoustic Mapping Reveals Hudson River Sediment Processes and Habitats

Rivers and estuaries around the world are the focus of human settlements and activities. Needs for clean water, ecosystem preservation, commercial navigation, industrial development, and recreational access compete for the use of estuaries, and management of these resources requires a detailed understanding of estuarine morphology and sediment dynamics. This article presents an overview of the first estuary-wide study of a heavily used estuary, the Hudson River, based on high-resolution acoustic mapping of the river bottom. The integration of three high-resolution acoustic methods with extensive sampling reveals an unexpected complexity of bottom features and allows detailed classification of the benthic environment in terms of riverbed morphology, sediment type, and sedimentary processes

Indonesian Throughflow drove Australian climate from humid Pliocene to arid Pleistocene

Late Miocene to mid-Pleistocene sedimentary proxy records reveal that northwest Australia underwent an abrupt transition from dry to humid climate conditions at 5.5 million years (Ma), likely receiving year-round rainfall, but after ~3.3 Ma, climate shifted toward an increasingly seasonal precipitation regime. The progressive constriction of the Indonesian Throughflow likely decreased continental humidity and transferred control of northwest Australian climate from the Pacific to the Indian Ocean, leading to drier conditions punctuated by monsoonal precipitation. The northwest dust pathway and fully established seasonal and orbitally controlled precipitation were in place by ~2.4 Ma, well after the intensification of Northern Hemisphere glaciation. The transition from humid to arid conditions was driven by changes in Pacific and Indian Ocean circulation and regional atmospheric moisture transport, influenced by the emerging Maritime Continent. We conclude that the Maritime Continent is the switchboard modulating teleconnections between tropical and high-latitude climate systems

Development of an improved blood-stage malaria vaccine targeting the essential RH5-CyRPA-RIPR invasion complex

Reticulocyte-binding protein homologue 5 (RH5), a leading blood-stage Plasmodium falciparum malaria vaccine target, interacts with cysteine-rich protective antigen (CyRPA) and RH5-interacting protein (RIPR) to form an essential heterotrimeric “RCR-complex”. We investigate whether RCR-complex vaccination can improve upon RH5 alone. Using monoclonal antibodies (mAbs) we show that parasite growth-inhibitory epitopes on each antigen are surface-exposed on the RCR-complex and that mAb pairs targeting different antigens can function additively or synergistically. However, immunisation of female rats with the RCR-complex fails to outperform RH5 alone due to immuno-dominance of RIPR coupled with inferior potency of anti-RIPR polyclonal IgG. We identify that all growth-inhibitory antibody epitopes of RIPR cluster within the C-terminal EGF-like domains and that a fusion of these domains to CyRPA, called “R78C”, combined with RH5, improves the level of in vitro parasite growth inhibition compared to RH5 alone. These preclinical data justify the advancement of the RH5.1 + R78C/Matrix-M™ vaccine candidate to Phase 1 clinical trial

Evidence for widespread creep on the flanks of the Sea of Marmara transform basin from marine geophysical data

"Wave" fields have long been recognized in marine sediments on the flanks of basins and oceans in both tectonically active and inactive environments. The origin of "waves" (hereafter called undulations) is controversial; competing models ascribe them to depositional processes, gravity-driven downslope creep or collapse, and/or tectonic shortening. Here we analyze pervasive undulation fields identified in swath bathymetry and new high-resolution multichannel seismic (MCS) reflection data from the Sea of Marmara, Turkey. Although they exhibit some of the classical features of sediment waves, the following distinctive characteristics exclude a purely depositional origin: (1) parallelism between the crests of the undulations and bathymetric contours over a wide range of orientations, (2) steep flanks of the undulations (up to ∼40°), and (3) increases in undulations amplitude with depth. We argue that the undulations are folds formed by gravity-driven downslope creep that have been augmented by depositional processes. These creep folds develop over long time periods (≥0.5 m.y.) and stand in contrast to geologically instantaneous collapse. Stratigraphic growth on the upslope limbs indicates that deposition contributes to the formation and upslope migration of the folds. The temporal and spatial evolution of the creep folds is clearly related to rapid tilting in this tectonically active transform basin

Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos

Prior GWAS have identified loci associated with red blood cell (RBC) traits in populations of European, African, and Asian ancestry. These studies have not included individuals with an Amerindian ancestral background, such as Hispanics/Latinos, nor evaluated the full spectrum of genomic variation beyond single nucleotide variants. Using a custom genotyping array enriched for Amerindian ancestral content and 1000 Genomes imputation, we performed GWAS in 12,502 participants of Hispanic Community Health Study and Study of Latinos (HCHS/SOL) for hematocrit, hemoglobin, RBC count, RBC distribution width (RDW), and RBC indices. Approximately 60% of previously reported RBC trait loci generalized to HCHS/SOL Hispanics/Latinos, including African ancestral alpha- and beta-globin gene variants. In addition to the known 3.8kb alpha-globin copy number variant, we identified an Amerindian ancestral association in an alpha-globin regulatory region on chromosome 16p13.3 for mean corpuscular volume and mean corpuscular hemoglobin. We also discovered and replicated three genome-wide significant variants in previously unreported loci for RDW (SLC12A2 rs17764730, PSMB5 rs941718), and hematocrit (PROX1 rs3754140). Among the proxy variants at the SLC12A2 locus we identified rs3812049, located in a bi-directional promoter between SLC12A2 (which encodes a red cell membrane ion-transport protein) and an upstream anti-sense long-noncoding RNA, LINC01184, as the likely causal variant. We further demonstrate that disruption of the regulatory element harboring rs3812049 affects transcription of SLC12A2 and LINC01184 in human erythroid progenitor cells. Together, these results reinforce the importance of genetic study of diverse ancestral populations, in particular Hispanics/Latinos