Examining the benefits of feedback: are monitoring skills implicated in successful performance?

The current set of experiments was designed to investigate whether monitoring skills are implicated in the effectiveness of receiving feedback on performance. This was examined by determining whether receiving feedback improves the retention of correct responses as well as improves memory performance (Experiment 1), whether participants detect and use false feedback (Experiment 2), and whether young children's memory performance improves from receiving feedback (Experiment 3). In addition, confidence ratings were taken as a measure of participants' ability to monitor their performance. The results revealed participants' confidence in their original responses influenced the effectiveness of feedback, and participants used the feedback to influence their memory and monitoring performance. These results imply participants' confidence influences the effects of receiving feedback

Longitudinal Assessment of Older Drivers in a DMV Setting

A brief battery of functional assessments designed to detect crash riskamong older drivers was developed and evaluated initially in 1999 in Marylandmotor vehicle licensing sites following the routine vision screening exam. Thisbattery contained a number of cognitive tests (e.g., UFOV® subtest 2, the closuresubtest of the Motor Free Visual Perception Test (MVPT), Trails A and B, cuedrecall, delayed recall), and several physical measures (e.g., Rapid Pace Walk,Head and Neck Rotation, Foot Tap, Arm Reach). Older adults (N=4,173; meanage = 69 years) were approached by the staff after license renewal and asked tohelp evaluate the brief battery. Of the 4,173 older adults approached at the fieldsites, 2,114 individuals 55-96 years of age participated. Subsequently, the originalsample of 2,114 participants was invited to come in once again, during their fiveyearlicense renewal cycle, and the functional tests were administered once again.To date, 939 individuals have completed the second screening evaluation. Anexamination of the crash data from the interval between assessments for theseindividuals indicates that the same cognitive measures are predictive of at-faultcrashes. Furthermore, approximately 10% of those passing the assessment in 1999are now failing the assessment in 2004. Performance-based cognitive measuresare predictive of future at-fault motor vehicle collisions among older adults.Cognitive performance, in particular, is a salient predictor of subsequent crashinvolvement among older adults. High-risk older drivers can be identified throughbrief, performance-based measures administered in a DMV setting

Volume 08

Introduction from Interim Dean Dr. Jennifer Apperson Indigenous Peoples and the Modern Era by Meghan Enzinna Who Says : How Selena Gomez and the Scene Attempt to Subvert the Popular Standards of Beauty by Casey Dawn Gailey Art by Raven Collins Meltdown on Social Media: Amy\u27s Baking Company Meets Kitchen Nightmares by Nathena Haddrill Art by Chiara Enriquez Design by Amelia Mcconnell Worth More Than a Thousand Words: A Visual Rhetorical Discussion of Virtual Reality by Examining Clouds Over Sidra by Alexander Morton Design by Emma Beckett The Sonata: An Analysis of Piano Sonata No. 14 in C Minor, K. 457 by Wolfgang Amadeus Mozart by Leah G. Parr Art by Briana Adhikusuma Skewed Perceptions of Masculinity in Chris Lynch\u27s Inexcusable by Taylor Embrey Photography by Rowan Davis Joy Like Short Grass : Death in James Dickey\u27s the Eagle\u27s Mile by Danielle Sisson Poster by Bianca Cherry Design by Melissa Cacho A Writer\u27s Evolution: Connecting Academic and Workplace Writing Within the Field of Nursing by Chloé Woodward Background and Research Designs on Service Dogs for Children with an Autism Spectrum Disorder by Catherine Rollins Photography by Carson Reeher Design by Landon Cooper Wallace Stevens: Meaning in Nature and Its Elements by Haley Vasquez Photography by Marlisha Stewart Building an Arcade Machine to Do Interdisciplinary Research into What Makes People Like Video Games by Eric Whitehead Poster by Sabrina Walker Design by James Bate

An Interprofessional Education Collaborative (IPEC) Competency-focused Workshop to Optimize Team Performance

We aimed to strengthen interprofessional (IP) teams’ competence in collaborative practice through a workshop series. Objectives included: 1) examine personal and professional values, and roles and their impact on collaborative practice, 2) apply relationship building principles to perform effectively as a team, 3) integrate quality improvement tools into work processes to aid team-based care. Published Core Competencies for IP Collaborative Practice delineate professionals\u27 skills in the art and science of working collaboratively, yet few professionals have had training to develop these skills. IP teams from academic and community-based settings, including long-term, acute, and ambulatory care, were recruited to participate in classroom-based workshops. Sixteen faculty from 7 professions developed three, 3-hour workshops. During the sessions, active learning strategies challenged teams to analyze their current practice. Between sessions, teams applied principles in completing application exercises. Session 1 addressed the domains of values/ethics and roles/responsibilities, session 2 addressed communication and teamwork, and session 3 introduced novel tools to evaluate and improve outcomes. Over two years, 42 participants from 10 teams representing 15 professions attended the workshops. Faculty used mixed method evaluations combining novel and existing scales. Participants rated (a) the overall impact of the workshop and (b) expectations for applying new knowledge to enhance team performance on 3-point scales. Mean ratings were high for workshop 1 (2.75, 2.78); 2 (2.82, 2.85); and 3 (2.75, 2.75). Forty-one participants rated themselves as competent on the individual workshop objectives. All participants would recommend the workshop to colleagues. The workshops were well received, resulted in improved self-reported competence, and high intention of applying what they learned to improve patient outcomes. In this age of complex medical systems the key to improved outcomes is better IP teamwork. We plan to offer the workshops semiannually with additional study to assess actual impact on work practice. Objectives: 1) Examine personal and professional values, and roles and their impact on collaborative practice. 2) Apply relationship building principles to perform effectively as a team. 3) Integrate quality improvement tools into work processes to aid team-based care

Being user-oriented: convergences, divergences, and the potentials for systematic dialogue between disciplines and between researchers, designers, and providers

The challenge this panel addresses is drawn from intersecting literature reviews and critical commentaries focusing on: 1) user studies in multiple fields; and 2) the difficulties of bringing different disciplines and perspectives to bear on user‐oriented research, design, and practice. 1 The challenge is that while we have made some progress in collaborative work, we have some distance to go to become user‐oriented in inter‐disciplinary and inter‐perspective ways. The varieties of our approaches and solutions are, as some observers suggest, an increasing cacophony. One major difficulty is that most discussions are solution‐oriented, offering arguments of this sort ‐‐ if only we addressed users in this way… Each solution becomes yet another addition to the cacophony. This panel implements a central approach documented for its utility by communication researchers and long used by communication mediators and negotiators ‐‐ that of focusing not on communication but rather on meta‐communication: communicating about communication. The intent in the context of this panel is to help us refocus attention from too frequent polarizations between alternative solutions to the possibility of coming to understand what is behind the alternatives and where they point to experientially‐based convergences and divergences, both of which might potentially contribute to synergies. The background project for this panel comes from a series of in‐depth interviews with expert researchers, designers, and providers in three field groupings ‐‐ library and information science; human computer interaction/information technology; and communication and media studies. One set of interviews involved 5‐hour focus groups with directors of academic and public libraries serving 44 colleges and universities in central Ohio; the second involved one‐on‐one interviews averaging 50 minutes with 81 nationally‐internationally known experts in the 3 fields, 25‐27 interviews per field. Using Dervin\u27s Sense‐Making Methodological approach to interviewing, the expert interviews of both kinds asked each interviewee: what he/she considered to be the big unanswered questions about users and what explained why the questions have not been answered; and, what he/she saw as hindering versus helping in attempts to communicate about users across disciplinary and perspective gaps. 2 The panel consists of six teams, two from each field. Prior to the panel presentation at ASIST, each team will have read the set of interviews and completed impressionistic essays of what patterns and themes they saw as emerging. At this stage, team members will purposively not homogenize their differences and most will write solo‐authored essays that will be placed on a web‐site accessible to ASIST members prior to the November meeting. In addition, at least one systematic analysis will be completed and available online. 3 At the ASIST panel, each team\u27s leader will present a brief and intentionally provocative impressionist account of what his/her team came to understand about our struggles communicating across fields and perspectives about users. Again, each team will purposively not homogenize its own differences in viewpoints, but rather highlight them as fodder for discussion. A major purpose will be to invite audience members to join the panel in discussion. At least 20 minutes will be left open for this purpose

H-NS plays a role in expression of Acinetobacter baumannii virulence features

Acinetobacter baumannii has become a major problem in the clinical setting with the prevalence of infections caused by multidrug-resistant strains on the increase. Nevertheless, only a limited number of molecular mechanisms involved in the success of A. baumannii as a human pathogen have been described. In this study, we examined the virulence features of a hypermotile derivative of A. baumannii strain ATCC 17978, which was found to display enhanced adherence to human pneumocytes and elevated levels of lethality toward Caenorhabditis elegans nematodes. Analysis of cellular lipids revealed modifications to the fatty acid composition, providing a possible explanation for the observed changes in hydrophobicity and subsequent alteration in adherence and motility. Comparison of the genome sequences of the hypermotile variant and parental strain revealed that an insertion sequence had disrupted an hns-like gene in the variant. This gene encodes a homologue of the histone-like nucleoid structuring (H-NS) protein, a known global transcriptional repressor. Transcriptome analysis identified the global effects of this mutation on gene expression, with major changes seen in the autotransporter Ata, a type VI secretion system, and a type I pilus cluster. Interestingly, isolation and analysis of a second independent hypermotile ATCC 17978 variant revealed a mutation to a residue within the DNA binding region of H-NS. Taken together, these mutants indicate that the phenotypic and transcriptomic differences seen are due to loss of regulatory control effected by H-NS.This work was supported by project grant 535053 to M.H.B. and I.T.P. from the National Health and Medical Research Council, Australia. B.A.E. is the recipient of a School of Biological Sciences Endeavor International Postgraduate Research Scholarship, and K.A.H. is supported by an APD fellowship from the Australian Research Council (DP110102680)

The X-ray Polarization Probe mission concept

The X-ray Polarization Probe (XPP) is a second generation X-ray polarimeter following up on the Imaging X-ray Polarimetry Explorer (IXPE). The XPP will offer true broadband polarimetery over the wide 0.2-60 keV bandpass in addition to imaging polarimetry from 2-8 keV. The extended energy bandpass and improvements in sensitivity will enable the simultaneous measurement of the polarization of several emission components. These measurements will give qualitatively new information about how compact objects work, and will probe fundamental physics, i.e. strong-field quantum electrodynamics and strong gravity.Comment: submitted to Astrophysics Decadal Survey as a State of the Profession white pape

Finding Diagnostically Useful Patterns in Quantitative Phenotypic Data.

Trio-based whole-exome sequence (WES) data have established confident genetic diagnoses in ∼40% of previously undiagnosed individuals recruited to the Deciphering Developmental Disorders (DDD) study. Here we aim to use the breadth of phenotypic information recorded in DDD to augment diagnosis and disease variant discovery in probands. Median Euclidean distances (mEuD) were employed as a simple measure of similarity of quantitative phenotypic data within sets of ≥10 individuals with plausibly causative de novo mutations (DNM) in 28 different developmental disorder genes. 13/28 (46.4%) showed significant similarity for growth or developmental milestone metrics, 10/28 (35.7%) showed similarity in HPO term usage, and 12/28 (43%) showed no phenotypic similarity. Pairwise comparisons of individuals with high-impact inherited variants to the 32 individuals with causative DNM in ANKRD11 using only growth z-scores highlighted 5 likely causative inherited variants and two unrecognized DNM resulting in an 18% diagnostic uplift for this gene. Using an independent approach, naive Bayes classification of growth and developmental data produced reasonably discriminative models for the 24 DNM genes with sufficiently complete data. An unsupervised naive Bayes classification of 6,993 probands with WES data and sufficient phenotypic information defined 23 in silico syndromes (ISSs) and was used to test a "phenotype first" approach to the discovery of causative genotypes using WES variants strictly filtered on allele frequency, mutation consequence, and evidence of constraint in humans. This highlighted heterozygous de novo nonsynonymous variants in SPTBN2 as causative in three DDD probands

Prevalence and architecture of de novo mutations in developmental disorders.

The genomes of individuals with severe, undiagnosed developmental disorders are enriched in damaging de novo mutations (DNMs) in developmentally important genes. Here we have sequenced the exomes of 4,293 families containing individuals with developmental disorders, and meta-analysed these data with data from another 3,287 individuals with similar disorders. We show that the most important factors influencing the diagnostic yield of DNMs are the sex of the affected individual, the relatedness of their parents, whether close relatives are affected and the parental ages. We identified 94 genes enriched in damaging DNMs, including 14 that previously lacked compelling evidence of involvement in developmental disorders. We have also characterized the phenotypic diversity among these disorders. We estimate that 42% of our cohort carry pathogenic DNMs in coding sequences; approximately half of these DNMs disrupt gene function and the remainder result in altered protein function. We estimate that developmental disorders caused by DNMs have an average prevalence of 1 in 213 to 1 in 448 births, depending on parental age. Given current global demographics, this equates to almost 400,000 children born per year